Bioresponsive materials View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-01

AUTHORS

Yue Lu, Alex A. Aimetti, Robert Langer, Zhen Gu

ABSTRACT

‘Smart’ bioresponsive materials that are sensitive to biological signals or to pathological abnormalities, and interact with or are actuated by them, are appealing therapeutic platforms for the development of next-generation precision medications. Armed with a better understanding of various biologically responsive mechanisms, researchers have made innovations in the areas of materials chemistry, biomolecular engineering, pharmaceutical science, and micro- and nanofabrication to develop bioresponsive materials for a range of applications, including controlled drug delivery, diagnostics, tissue engineering and biomedical devices. This Review highlights recent advances in the design of smart materials capable of responding to the physiological environment, to biomarkers and to biological particulates. Key design principles, challenges and future directions, including clinical translation, of bioresponsive materials are also discussed. More... »

PAGES

natrevmats201675

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  • Identifiers

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    http://scigraph.springernature.com/pub.10.1038/natrevmats.2016.75

    DOI

    http://dx.doi.org/10.1038/natrevmats.2016.75

    DIMENSIONS

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