Caspase-3-dependent apoptosis in cardiac myxoma: not associated with human papillomavirus or Epstein–Barr virus View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-06

AUTHORS

Chi-Hsiao Yeh, Chyong-Huey Lai, Hsin-Chiung Lin, Hsueh-Hua Wu, Jaw-Ji Chu, Ngan-Ming Tseng, Pao-Hsien Chu, Pyng-Jing Lin, Shang L Huang, Shih-Ming Jung, Tzu-Fang Shiu

ABSTRACT

Cardiac myxoma is the most common tumor of the heart, has a variable clinical presentation and immunohistochemical profile. Viral infections, such as herpes simplex virus, human papillomavirus (HPV), and Epstein-Barr virus (EBV), may play an important role in the causes of cardiac myxoma. This investigation will demonstrate caspase-3-dependent apoptosis in cardiac myxoma without HPV or EBV infection. This study included 15 patients with cardiac myxoma, who were treated with surgical excision of the lesion. Data were collected on detailed clinical parameters. Terminal deoxynucleotidyl transferase nick-end labeling assay, electrophoresis, and caspase-3 immunohistochemical studies were performed to characterize apoptosis. Genechip containing 39 subtypes was used to elucidate HPV; and polymerase chain reaction to detect LMP-1 gene of EBV. The patient population comprised of eight (53%) women and seven (47%) men. The mean age of patient participants was 45 years, with an age range of 30-70 years. All patient cases were sporadic myxomas rather than familial myxomas. The patient presentations included dyspnea (53%), asymptomatic (27%), stroke (7%), chest pain (7%), and fever (7%). All lesions were located in the left atrium. The individual patient cases of myxoma did not differ in location or clinical event in terms of pathological scores, such as vascular proliferation, inflammation, cellularity, hyaline, calcification, or thrombosis. Cardiac myxoma is characterized by apoptosis through caspase-dependent pathway. HPV or EBV was not detected in any of the study patient samples. In conclusion, no viral genomes of HPV or EBV were detected in these 15 patients. This study demonstrates that caspase-3-dependent apoptosis in cardiac myxoma is not dependent on concurrence of previous HPV and/or EBV infection. More... »

PAGES

822

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/modpathol.3800364

DOI

http://dx.doi.org/10.1038/modpathol.3800364

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038329365

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15696123


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apoptosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Caspase 3", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Caspases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epstein-Barr Virus Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Herpesvirus 4, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Situ Nick-End Labeling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myxoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Papillomaviridae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Papillomavirus Infections", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Division of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yeh", 
        "givenName": "Chi-Hsiao", 
        "id": "sg:person.013105446000.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013105446000.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lai", 
        "givenName": "Chyong-Huey", 
        "id": "sg:person.015460764715.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015460764715.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Hsin-Chiung", 
        "id": "sg:person.01123216324.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123216324.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "The Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wu", 
        "givenName": "Hsueh-Hua", 
        "id": "sg:person.01063053447.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063053447.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Division of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chu", 
        "givenName": "Jaw-Ji", 
        "id": "sg:person.01033705161.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033705161.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Department of Radiation Oncology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tseng", 
        "givenName": "Ngan-Ming", 
        "id": "sg:person.01325707502.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325707502.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "The Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chu", 
        "givenName": "Pao-Hsien", 
        "id": "sg:person.016666024317.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016666024317.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Division of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Pyng-Jing", 
        "id": "sg:person.0603250155.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603250155.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "Shang L", 
        "id": "sg:person.0615465045.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615465045.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jung", 
        "givenName": "Shih-Ming", 
        "id": "sg:person.01055103124.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055103124.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chang Gung Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413801.f", 
          "name": [
            "The Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shiu", 
        "givenName": "Tzu-Fang", 
        "id": "sg:person.01305560124.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305560124.47"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1080/13550280390173427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002506702", 
          "https://doi.org/10.1080/13550280390173427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-8258(91)90238-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009288911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jgm.583", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009868407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.160.5.602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011035803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003226-200103000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011046079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003226-200103000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011046079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198906013202202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011629842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000065609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015966631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1054-8807(02)00112-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016099869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1054-8807(02)00112-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016099869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1368-5031.2004.00118.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016732945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-8278(03)00385-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020614745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-8278(03)00385-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020614745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.285.14.1841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021484913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.123.5.1379", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022828471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.123.5.1379", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022828471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/excr.2001.5274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025266541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9440(10)63595-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026246576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005537-200306000-00025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026954245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005537-200306000-00025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026954245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s007050170048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028286623", 
          "https://doi.org/10.1007/s007050170048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mhj.2000.107176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030662354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1368-5031.2004.00042.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032871807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.66.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036833993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199512143332407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039052560"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.200324509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039331625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcp/100.6.671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041684888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-0670-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043663480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1100369", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047274383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1048-891x.2004.14418.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048540420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2613.2001.iep195.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050633135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1309/rvup-qmu3-5x6w-3cq1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052135828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005792-200105000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053268801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005792-200105000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053268801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00430-003-0213-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053646949", 
          "https://doi.org/10.1007/s00430-003-0213-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1076/ceyr.26.3.165.14899", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058249917"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/vir.0.80140-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060400444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2741/962", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070916847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-132-8-200004180-00028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073704087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074263437", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074741984", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075175862", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082894952", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-06", 
    "datePublishedReg": "2005-06-01", 
    "description": "Cardiac myxoma is the most common tumor of the heart, has a variable clinical presentation and immunohistochemical profile. Viral infections, such as herpes simplex virus, human papillomavirus (HPV), and Epstein-Barr virus (EBV), may play an important role in the causes of cardiac myxoma. This investigation will demonstrate caspase-3-dependent apoptosis in cardiac myxoma without HPV or EBV infection. This study included 15 patients with cardiac myxoma, who were treated with surgical excision of the lesion. Data were collected on detailed clinical parameters. Terminal deoxynucleotidyl transferase nick-end labeling assay, electrophoresis, and caspase-3 immunohistochemical studies were performed to characterize apoptosis. Genechip containing 39 subtypes was used to elucidate HPV; and polymerase chain reaction to detect LMP-1 gene of EBV. The patient population comprised of eight (53%) women and seven (47%) men. The mean age of patient participants was 45 years, with an age range of 30-70 years. All patient cases were sporadic myxomas rather than familial myxomas. The patient presentations included dyspnea (53%), asymptomatic (27%), stroke (7%), chest pain (7%), and fever (7%). All lesions were located in the left atrium. The individual patient cases of myxoma did not differ in location or clinical event in terms of pathological scores, such as vascular proliferation, inflammation, cellularity, hyaline, calcification, or thrombosis. Cardiac myxoma is characterized by apoptosis through caspase-dependent pathway. HPV or EBV was not detected in any of the study patient samples. In conclusion, no viral genomes of HPV or EBV were detected in these 15 patients. This study demonstrates that caspase-3-dependent apoptosis in cardiac myxoma is not dependent on concurrence of previous HPV and/or EBV infection.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/modpathol.3800364", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1098208", 
        "issn": [
          "0893-3952", 
          "1530-0285"
        ], 
        "name": "Modern Pathology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "name": "Caspase-3-dependent apoptosis in cardiac myxoma: not associated with human papillomavirus or Epstein\u2013Barr virus", 
    "pagination": "822", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b6964e514a36b38fd59800a9d00be22265dd4b5089b65b4f3bf52904704f0270"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15696123"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8806605"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/modpathol.3800364"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1038329365"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/modpathol.3800364", 
      "https://app.dimensions.ai/details/publication/pub.1038329365"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87088_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/3800364"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/modpathol.3800364'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/modpathol.3800364'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/modpathol.3800364'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/modpathol.3800364'


 

This table displays all metadata directly associated to this object as RDF triples.

326 TRIPLES      21 PREDICATES      84 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/modpathol.3800364 schema:about N003e1398f44a4ecfb6bbba2cda31b35a
2 N04ae80c883da45f0bcbcd680ddc106c5
3 N158332f3a6dc40d4981dbeb87cd7ef2a
4 N2140ce088d2e44bab8f7a6593a0d7308
5 N24e173bbd26e42a3b98dc3abd8f487fa
6 N25be2e4a87b64fd9b26a6237421c59e2
7 N2e9f989d14484c5e8235420ce5f7bba1
8 N3969eb8bd65249e5921e5dc52597f766
9 N3a49ee6b428d496c919001d21b3f513b
10 N3add51a869914b9992e4bafbf39e775f
11 N421ad3258faa453aa95b1b7dc6fb0b79
12 N4f894b31347646a8adc73b4aeb3c4c17
13 N5093b6906cb74bb7aea1a8e8d715d8aa
14 N5c4f35811fad4bf1a727f62b6a990df9
15 N8bf935baa74b4384a28af62f54a7f7e7
16 Nd51bedcdea9b43e0ba6c17b11f359656
17 Nef699e0da374432c99341e61d02663c7
18 Nf7a4a963aa94401588a76c7a11e763be
19 anzsrc-for:11
20 anzsrc-for:1102
21 schema:author N67832163e47548cc945cdf2af064a8d0
22 schema:citation sg:pub.10.1007/s00430-003-0213-y
23 sg:pub.10.1007/s007050170048
24 sg:pub.10.1080/13550280390173427
25 https://app.dimensions.ai/details/publication/pub.1074263437
26 https://app.dimensions.ai/details/publication/pub.1074741984
27 https://app.dimensions.ai/details/publication/pub.1075175862
28 https://app.dimensions.ai/details/publication/pub.1082894952
29 https://doi.org/10.1001/archinte.160.5.602
30 https://doi.org/10.1001/jama.285.14.1841
31 https://doi.org/10.1002/eji.200324509
32 https://doi.org/10.1002/jgm.583
33 https://doi.org/10.1006/excr.2001.5274
34 https://doi.org/10.1016/0090-8258(91)90238-z
35 https://doi.org/10.1016/s0002-9440(10)63595-x
36 https://doi.org/10.1016/s0168-8278(03)00385-4
37 https://doi.org/10.1016/s1054-8807(02)00112-6
38 https://doi.org/10.1056/nejm198906013202202
39 https://doi.org/10.1056/nejm199512143332407
40 https://doi.org/10.1067/mhj.2000.107176
41 https://doi.org/10.1076/ceyr.26.3.165.14899
42 https://doi.org/10.1093/ajcp/100.6.671
43 https://doi.org/10.1097/00003226-200103000-00010
44 https://doi.org/10.1097/00005537-200306000-00025
45 https://doi.org/10.1097/00005792-200105000-00002
46 https://doi.org/10.1099/vir.0.80140-0
47 https://doi.org/10.1111/j.1048-891x.2004.14418.x
48 https://doi.org/10.1111/j.1365-2613.2001.iep195.x
49 https://doi.org/10.1111/j.1368-5031.2004.00042.x
50 https://doi.org/10.1111/j.1368-5031.2004.00118.x
51 https://doi.org/10.1126/science.1100369
52 https://doi.org/10.1158/1078-0432.ccr-0670-3
53 https://doi.org/10.1159/000065609
54 https://doi.org/10.1253/circj.66.1
55 https://doi.org/10.1309/rvup-qmu3-5x6w-3cq1
56 https://doi.org/10.1378/chest.123.5.1379
57 https://doi.org/10.2741/962
58 https://doi.org/10.7326/0003-4819-132-8-200004180-00028
59 schema:datePublished 2005-06
60 schema:datePublishedReg 2005-06-01
61 schema:description Cardiac myxoma is the most common tumor of the heart, has a variable clinical presentation and immunohistochemical profile. Viral infections, such as herpes simplex virus, human papillomavirus (HPV), and Epstein-Barr virus (EBV), may play an important role in the causes of cardiac myxoma. This investigation will demonstrate caspase-3-dependent apoptosis in cardiac myxoma without HPV or EBV infection. This study included 15 patients with cardiac myxoma, who were treated with surgical excision of the lesion. Data were collected on detailed clinical parameters. Terminal deoxynucleotidyl transferase nick-end labeling assay, electrophoresis, and caspase-3 immunohistochemical studies were performed to characterize apoptosis. Genechip containing 39 subtypes was used to elucidate HPV; and polymerase chain reaction to detect LMP-1 gene of EBV. The patient population comprised of eight (53%) women and seven (47%) men. The mean age of patient participants was 45 years, with an age range of 30-70 years. All patient cases were sporadic myxomas rather than familial myxomas. The patient presentations included dyspnea (53%), asymptomatic (27%), stroke (7%), chest pain (7%), and fever (7%). All lesions were located in the left atrium. The individual patient cases of myxoma did not differ in location or clinical event in terms of pathological scores, such as vascular proliferation, inflammation, cellularity, hyaline, calcification, or thrombosis. Cardiac myxoma is characterized by apoptosis through caspase-dependent pathway. HPV or EBV was not detected in any of the study patient samples. In conclusion, no viral genomes of HPV or EBV were detected in these 15 patients. This study demonstrates that caspase-3-dependent apoptosis in cardiac myxoma is not dependent on concurrence of previous HPV and/or EBV infection.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree true
65 schema:isPartOf Na3d21157dff44bbaa8b2c154ce18c418
66 Nf2dab6cd8cac4ee5b82c54bcdd4bb8a1
67 sg:journal.1098208
68 schema:name Caspase-3-dependent apoptosis in cardiac myxoma: not associated with human papillomavirus or Epstein–Barr virus
69 schema:pagination 822
70 schema:productId N0b46a116603f4020ae02da54d064ec4d
71 N9265c82a8a6b4aac9620b69e0ab1b924
72 Nab973a5a56514b389ce67ef374d650d9
73 Nb5235c6500ef41a8bce9a8eb964a9023
74 Nf0a1fbd774e247eda651b36e311e59fb
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038329365
76 https://doi.org/10.1038/modpathol.3800364
77 schema:sdDatePublished 2019-04-11T12:22
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher Ne4772892d5884682999f39da9025cc93
80 schema:url https://www.nature.com/articles/3800364
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N003e1398f44a4ecfb6bbba2cda31b35a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Apoptosis
86 rdf:type schema:DefinedTerm
87 N04ae80c883da45f0bcbcd680ddc106c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Adult
89 rdf:type schema:DefinedTerm
90 N0b46a116603f4020ae02da54d064ec4d schema:name doi
91 schema:value 10.1038/modpathol.3800364
92 rdf:type schema:PropertyValue
93 N109c4c98b80b4539ba48783967e8cead rdf:first sg:person.01325707502.94
94 rdf:rest Ncd94f5034eb9465db41196b222ab1d8a
95 N1226ff2e7d2541dda88aac715c79adf7 rdf:first sg:person.01063053447.71
96 rdf:rest N6768514e4a974314b25cce05b333034b
97 N158332f3a6dc40d4981dbeb87cd7ef2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Middle Aged
99 rdf:type schema:DefinedTerm
100 N198867cc7e3b431a8e69f01c8f270b26 rdf:first sg:person.015460764715.11
101 rdf:rest N7672edd77ba943a9b5cc29494d2ce6cf
102 N2140ce088d2e44bab8f7a6593a0d7308 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Aged
104 rdf:type schema:DefinedTerm
105 N24e173bbd26e42a3b98dc3abd8f487fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name In Situ Nick-End Labeling
107 rdf:type schema:DefinedTerm
108 N25be2e4a87b64fd9b26a6237421c59e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Epstein-Barr Virus Infections
110 rdf:type schema:DefinedTerm
111 N2e9f989d14484c5e8235420ce5f7bba1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Female
113 rdf:type schema:DefinedTerm
114 N3969eb8bd65249e5921e5dc52597f766 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Herpesvirus 4, Human
116 rdf:type schema:DefinedTerm
117 N3a49ee6b428d496c919001d21b3f513b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Immunohistochemistry
119 rdf:type schema:DefinedTerm
120 N3add51a869914b9992e4bafbf39e775f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Papillomaviridae
122 rdf:type schema:DefinedTerm
123 N421ad3258faa453aa95b1b7dc6fb0b79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Caspase 3
125 rdf:type schema:DefinedTerm
126 N4f894b31347646a8adc73b4aeb3c4c17 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Heart Neoplasms
128 rdf:type schema:DefinedTerm
129 N5093b6906cb74bb7aea1a8e8d715d8aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Caspases
131 rdf:type schema:DefinedTerm
132 N546e4e9bd2eb40e3826767d85ccabe2b rdf:first sg:person.0615465045.04
133 rdf:rest Nd79c3d7f6a324769af8bf507350b4e1b
134 N5c4f35811fad4bf1a727f62b6a990df9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Male
136 rdf:type schema:DefinedTerm
137 N6768514e4a974314b25cce05b333034b rdf:first sg:person.01033705161.19
138 rdf:rest N109c4c98b80b4539ba48783967e8cead
139 N67832163e47548cc945cdf2af064a8d0 rdf:first sg:person.013105446000.39
140 rdf:rest N198867cc7e3b431a8e69f01c8f270b26
141 N7672edd77ba943a9b5cc29494d2ce6cf rdf:first sg:person.01123216324.65
142 rdf:rest N1226ff2e7d2541dda88aac715c79adf7
143 N8bf935baa74b4384a28af62f54a7f7e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Humans
145 rdf:type schema:DefinedTerm
146 N9265c82a8a6b4aac9620b69e0ab1b924 schema:name readcube_id
147 schema:value b6964e514a36b38fd59800a9d00be22265dd4b5089b65b4f3bf52904704f0270
148 rdf:type schema:PropertyValue
149 Na3d21157dff44bbaa8b2c154ce18c418 schema:volumeNumber 18
150 rdf:type schema:PublicationVolume
151 Nab973a5a56514b389ce67ef374d650d9 schema:name pubmed_id
152 schema:value 15696123
153 rdf:type schema:PropertyValue
154 Nb5235c6500ef41a8bce9a8eb964a9023 schema:name dimensions_id
155 schema:value pub.1038329365
156 rdf:type schema:PropertyValue
157 Ncd94f5034eb9465db41196b222ab1d8a rdf:first sg:person.016666024317.12
158 rdf:rest Nef2fe8602fcf423fb92fcdc408d29143
159 Nd51bedcdea9b43e0ba6c17b11f359656 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Papillomavirus Infections
161 rdf:type schema:DefinedTerm
162 Nd79c3d7f6a324769af8bf507350b4e1b rdf:first sg:person.01055103124.19
163 rdf:rest Nfbd8398f5482458d86ece94bf4c62cc9
164 Ne4772892d5884682999f39da9025cc93 schema:name Springer Nature - SN SciGraph project
165 rdf:type schema:Organization
166 Nef2fe8602fcf423fb92fcdc408d29143 rdf:first sg:person.0603250155.09
167 rdf:rest N546e4e9bd2eb40e3826767d85ccabe2b
168 Nef699e0da374432c99341e61d02663c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name DNA, Viral
170 rdf:type schema:DefinedTerm
171 Nf0a1fbd774e247eda651b36e311e59fb schema:name nlm_unique_id
172 schema:value 8806605
173 rdf:type schema:PropertyValue
174 Nf2dab6cd8cac4ee5b82c54bcdd4bb8a1 schema:issueNumber 6
175 rdf:type schema:PublicationIssue
176 Nf7a4a963aa94401588a76c7a11e763be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Myxoma
178 rdf:type schema:DefinedTerm
179 Nfbd8398f5482458d86ece94bf4c62cc9 rdf:first sg:person.01305560124.47
180 rdf:rest rdf:nil
181 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
182 schema:name Medical and Health Sciences
183 rdf:type schema:DefinedTerm
184 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
185 schema:name Cardiorespiratory Medicine and Haematology
186 rdf:type schema:DefinedTerm
187 sg:journal.1098208 schema:issn 0893-3952
188 1530-0285
189 schema:name Modern Pathology
190 rdf:type schema:Periodical
191 sg:person.01033705161.19 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
192 schema:familyName Chu
193 schema:givenName Jaw-Ji
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033705161.19
195 rdf:type schema:Person
196 sg:person.01055103124.19 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
197 schema:familyName Jung
198 schema:givenName Shih-Ming
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055103124.19
200 rdf:type schema:Person
201 sg:person.01063053447.71 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
202 schema:familyName Wu
203 schema:givenName Hsueh-Hua
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063053447.71
205 rdf:type schema:Person
206 sg:person.01123216324.65 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
207 schema:familyName Lin
208 schema:givenName Hsin-Chiung
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123216324.65
210 rdf:type schema:Person
211 sg:person.01305560124.47 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
212 schema:familyName Shiu
213 schema:givenName Tzu-Fang
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305560124.47
215 rdf:type schema:Person
216 sg:person.013105446000.39 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
217 schema:familyName Yeh
218 schema:givenName Chi-Hsiao
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013105446000.39
220 rdf:type schema:Person
221 sg:person.01325707502.94 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
222 schema:familyName Tseng
223 schema:givenName Ngan-Ming
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325707502.94
225 rdf:type schema:Person
226 sg:person.015460764715.11 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
227 schema:familyName Lai
228 schema:givenName Chyong-Huey
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015460764715.11
230 rdf:type schema:Person
231 sg:person.016666024317.12 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
232 schema:familyName Chu
233 schema:givenName Pao-Hsien
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016666024317.12
235 rdf:type schema:Person
236 sg:person.0603250155.09 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
237 schema:familyName Lin
238 schema:givenName Pyng-Jing
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603250155.09
240 rdf:type schema:Person
241 sg:person.0615465045.04 schema:affiliation https://www.grid.ac/institutes/grid.413801.f
242 schema:familyName Huang
243 schema:givenName Shang L
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615465045.04
245 rdf:type schema:Person
246 sg:pub.10.1007/s00430-003-0213-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1053646949
247 https://doi.org/10.1007/s00430-003-0213-y
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/s007050170048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028286623
250 https://doi.org/10.1007/s007050170048
251 rdf:type schema:CreativeWork
252 sg:pub.10.1080/13550280390173427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002506702
253 https://doi.org/10.1080/13550280390173427
254 rdf:type schema:CreativeWork
255 https://app.dimensions.ai/details/publication/pub.1074263437 schema:CreativeWork
256 https://app.dimensions.ai/details/publication/pub.1074741984 schema:CreativeWork
257 https://app.dimensions.ai/details/publication/pub.1075175862 schema:CreativeWork
258 https://app.dimensions.ai/details/publication/pub.1082894952 schema:CreativeWork
259 https://doi.org/10.1001/archinte.160.5.602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011035803
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1001/jama.285.14.1841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021484913
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1002/eji.200324509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039331625
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1002/jgm.583 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009868407
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1006/excr.2001.5274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025266541
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/0090-8258(91)90238-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1009288911
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0002-9440(10)63595-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026246576
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/s0168-8278(03)00385-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020614745
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/s1054-8807(02)00112-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016099869
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1056/nejm198906013202202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011629842
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1056/nejm199512143332407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039052560
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1067/mhj.2000.107176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030662354
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1076/ceyr.26.3.165.14899 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058249917
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1093/ajcp/100.6.671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041684888
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1097/00003226-200103000-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011046079
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1097/00005537-200306000-00025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026954245
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1097/00005792-200105000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053268801
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1099/vir.0.80140-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060400444
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1111/j.1048-891x.2004.14418.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048540420
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1111/j.1365-2613.2001.iep195.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050633135
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1111/j.1368-5031.2004.00042.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032871807
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1111/j.1368-5031.2004.00118.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016732945
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1126/science.1100369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047274383
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1158/1078-0432.ccr-0670-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043663480
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1159/000065609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015966631
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1253/circj.66.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036833993
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1309/rvup-qmu3-5x6w-3cq1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052135828
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1378/chest.123.5.1379 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022828471
314 rdf:type schema:CreativeWork
315 https://doi.org/10.2741/962 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070916847
316 rdf:type schema:CreativeWork
317 https://doi.org/10.7326/0003-4819-132-8-200004180-00028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073704087
318 rdf:type schema:CreativeWork
319 https://www.grid.ac/institutes/grid.413801.f schema:alternateName Chang Gung Memorial Hospital
320 schema:name Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
321 Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
322 Department of Radiation Oncology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
323 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
324 Division of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
325 The Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
326 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...