Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-05

AUTHORS

Benjamin C Calhoun, Amy Sobel, Richard L White, Matt Gromet, Teresa Flippo, Terry Sarantou, Chad A Livasy

ABSTRACT

Flat epithelial atypia of the breast commonly co-exists with atypical ductal hyperplasia, lobular neoplasia, and indolent forms of invasive carcinomas such as tubular carcinoma. Most patients with pure flat epithelial atypia on core biopsy undergo surgical excision to evaluate for carcinoma in the adjacent breast tissue. Studies to date have reported varying upgrade rates with most recommending follow-up excision. These studies have often lacked detailed radiographic correlation, central review by breast pathologists and information regarding the biology of the carcinomas identified upon excision. In this study, we report the frequency of upgrade to invasive carcinoma or ductal carcinoma in situ in excision specimens following a diagnosis of pure flat epithelial atypia on core biopsy. Radiographic correlation is performed for each case and grade/receptor status of detected carcinomas is reported. Seventy-three (73) core biopsies containing pure flat epithelial atypia were identified from our files, meeting inclusion criteria for the study. In the subsequent excision biopsies, five (7%) cases contained invasive carcinoma or ductal carcinoma in situ and seventeen (23%) contained atypical ductal hyperplasia or lobular neoplasia. All of the ductal carcinoma in situ cases with estrogen receptor results were estrogen receptor positive and intermediate grade. The invasive tumors were small (pT1a) hormone receptor-positive, HER2-negative, low-grade invasive ductal or tubular carcinomas with negative sentinel lymph-node biopsies. No upgrades were identified in the 14 patients who had all of their calcifications removed by the stereotactic core biopsy. Our rate of upgrade to carcinoma, once cases with discordant imaging are excluded, is at the lower end of the range reported in the literature. Given the low upgrade rate and indolent nature of the carcinomas associated with flat epithelial atypia, case management may be individualized based on clinical and radiographic findings. Excision may not be necessary for patients without remaining calcifications following core biopsy. More... »

PAGES

670

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/modpathol.2014.159

DOI

http://dx.doi.org/10.1038/modpathol.2014.159

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041068575

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25412845


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biopsy, Large-Core Needle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Precancerous Conditions", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Levine Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.468189.a", 
          "name": [
            "Carolinas Pathology Group, Levine Cancer Institute, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Calhoun", 
        "givenName": "Benjamin C", 
        "id": "sg:person.010252703435.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010252703435.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Carolinas Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.239494.1", 
          "name": [
            "Charlotte Radiology, Carolinas Medical Center, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sobel", 
        "givenName": "Amy", 
        "id": "sg:person.0616076375.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616076375.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Levine Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.468189.a", 
          "name": [
            "Department of Surgery, Division of Surgical Oncology, Levine Cancer Institute, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Richard L", 
        "id": "sg:person.01177342226.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177342226.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Carolinas Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.239494.1", 
          "name": [
            "Charlotte Radiology, Carolinas Medical Center, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gromet", 
        "givenName": "Matt", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Levine Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.468189.a", 
          "name": [
            "Department of Surgery, Division of Surgical Oncology, Levine Cancer Institute, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Flippo", 
        "givenName": "Teresa", 
        "id": "sg:person.010346216553.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010346216553.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Levine Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.468189.a", 
          "name": [
            "Department of Surgery, Division of Surgical Oncology, Levine Cancer Institute, Charlotte, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sarantou", 
        "givenName": "Terry", 
        "id": "sg:person.0770003170.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770003170.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Carolinas Pathology Group, Levine Cancer Institute, Charlotte, NC, USA", 
            "Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Livasy", 
        "givenName": "Chad A", 
        "id": "sg:person.0707456700.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707456700.38"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ncponc0109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001904623", 
          "https://doi.org/10.1038/ncponc0109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncponc0109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001904623", 
          "https://doi.org/10.1038/ncponc0109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1309/ajcpldg6tt7vahph", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002200638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5858/arpa.2012-0297-oa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002595974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-197211000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006059513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-197211000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006059513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-011-1839-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006502771", 
          "https://doi.org/10.1007/s10549-011-1839-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.22408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007176956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.suronc.2009.08.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008133091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198501173120303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010245188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diii.2013.01.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010614467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.humpath.2006.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011341289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-011-2034-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013038864", 
          "https://doi.org/10.1245/s10434-011-2034-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2559.2010.03568.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013071724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2559.2010.03568.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013071724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clbc.2013.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017035533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000213368.41251.b9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017049656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000213368.41251.b9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017049656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000213368.41251.b9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017049656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-012-1312-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017132886", 
          "https://doi.org/10.1007/s00428-012-1312-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr1367", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017738976", 
          "https://doi.org/10.1186/bcr1367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.sembd.2006.06.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019315768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.23873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020366545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1097/01.mp.0000051930.68104.92", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020743244", 
          "https://doi.org/10.1097/01.mp.0000051930.68104.92"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.breast.2014.01.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022540804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e318233523f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023151898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e318233523f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023151898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.2009.21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023339482", 
          "https://doi.org/10.1038/modpathol.2009.21"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e318161d1a5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025042539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e318161d1a5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025042539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-194502000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025664760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-194502000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025664760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-012-2591-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025867608", 
          "https://doi.org/10.1245/s10434-012-2591-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjsurg.2004.06.037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027129322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030437381", 
          "https://doi.org/10.1038/modpathol.3800514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030437381", 
          "https://doi.org/10.1038/modpathol.3800514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5858/arpa.2013-0763-ed", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032396075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/tbj.12039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034649428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038084345", 
          "https://doi.org/10.1038/modpathol.3800014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038084345", 
          "https://doi.org/10.1038/modpathol.3800014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-012-1279-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038830976", 
          "https://doi.org/10.1007/s00428-012-1279-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e31819d0a4d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039318612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e31819d0a4d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039318612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e31819d0a4d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039318612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-012-2846-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039782251", 
          "https://doi.org/10.1245/s10434-012-2846-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00125480-200305000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042629803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00125480-200305000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042629803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000146013.76881.d9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046023790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000146013.76881.d9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046023790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2013.108415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046777432"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.humpath.2009.09.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046969801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr2624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048726884", 
          "https://doi.org/10.1186/bcr2624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr2624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048726884", 
          "https://doi.org/10.1186/bcr2624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-010-1208-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051588964", 
          "https://doi.org/10.1007/s10549-010-1208-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-010-1208-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051588964", 
          "https://doi.org/10.1007/s10549-010-1208-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000157295.93914.3b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051639767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000157295.93914.3b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051639767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.pas.0000157295.93914.3b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051639767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199812000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199812000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199812000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.11.7717", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069302092"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-05", 
    "datePublishedReg": "2015-05-01", 
    "description": "Flat epithelial atypia of the breast commonly co-exists with atypical ductal hyperplasia, lobular neoplasia, and indolent forms of invasive carcinomas such as tubular carcinoma. Most patients with pure flat epithelial atypia on core biopsy undergo surgical excision to evaluate for carcinoma in the adjacent breast tissue. Studies to date have reported varying upgrade rates with most recommending follow-up excision. These studies have often lacked detailed radiographic correlation, central review by breast pathologists and information regarding the biology of the carcinomas identified upon excision. In this study, we report the frequency of upgrade to invasive carcinoma or ductal carcinoma in situ in excision specimens following a diagnosis of pure flat epithelial atypia on core biopsy. Radiographic correlation is performed for each case and grade/receptor status of detected carcinomas is reported. Seventy-three (73) core biopsies containing pure flat epithelial atypia were identified from our files, meeting inclusion criteria for the study. In the subsequent excision biopsies, five (7%) cases contained invasive carcinoma or ductal carcinoma in situ and seventeen (23%) contained atypical ductal hyperplasia or lobular neoplasia. All of the ductal carcinoma in situ cases with estrogen receptor results were estrogen receptor positive and intermediate grade. The invasive tumors were small (pT1a) hormone receptor-positive, HER2-negative, low-grade invasive ductal or tubular carcinomas with negative sentinel lymph-node biopsies. No upgrades were identified in the 14 patients who had all of their calcifications removed by the stereotactic core biopsy. Our rate of upgrade to carcinoma, once cases with discordant imaging are excluded, is at the lower end of the range reported in the literature. Given the low upgrade rate and indolent nature of the carcinomas associated with flat epithelial atypia, case management may be individualized based on clinical and radiographic findings. Excision may not be necessary for patients without remaining calcifications following core biopsy. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/modpathol.2014.159", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1098208", 
        "issn": [
          "0893-3952", 
          "1530-0285"
        ], 
        "name": "Modern Pathology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "28"
      }
    ], 
    "name": "Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies", 
    "pagination": "670", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c3a2e9ca71f692dd264c53ca7f231135900d37b82294a3f9e3a1d2b8956cae37"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25412845"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8806605"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/modpathol.2014.159"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1041068575"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/modpathol.2014.159", 
      "https://app.dimensions.ai/details/publication/pub.1041068575"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000434.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/modpathol2014159"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2014.159'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2014.159'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2014.159'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2014.159'


 

This table displays all metadata directly associated to this object as RDF triples.

298 TRIPLES      21 PREDICATES      81 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/modpathol.2014.159 schema:about N108af180495549c0b82cb6d6f701e6ef
2 N17b01d9baf1443099e6dc5699b35863e
3 N2363a23569bc4bd18121c4988668f760
4 N2b3f042f3ca743e0878935f3dbda1124
5 N2daa8cad15df42828496c39b42b017f7
6 N608bfe0487004bc2ae93c5731c4e6f8e
7 N77b149d3ac6c4d74a67f7f517aede07c
8 Nbb306038069947a6ab7adeaecf8302d3
9 Nde785ee0c0bc405faf6e4ed19ec5afb1
10 Nf13e8de9185a43d29004e0d7e07785b0
11 anzsrc-for:11
12 anzsrc-for:1112
13 schema:author N5d87bf7e1e1b41c38c7218a5c3104242
14 schema:citation sg:pub.10.1007/s00428-012-1279-y
15 sg:pub.10.1007/s00428-012-1312-1
16 sg:pub.10.1007/s10549-010-1208-1
17 sg:pub.10.1007/s10549-011-1839-x
18 sg:pub.10.1038/modpathol.2009.21
19 sg:pub.10.1038/modpathol.3800014
20 sg:pub.10.1038/modpathol.3800514
21 sg:pub.10.1038/ncponc0109
22 sg:pub.10.1097/01.mp.0000051930.68104.92
23 sg:pub.10.1186/bcr1367
24 sg:pub.10.1186/bcr2624
25 sg:pub.10.1245/s10434-011-2034-3
26 sg:pub.10.1245/s10434-012-2591-0
27 sg:pub.10.1245/s10434-012-2846-9
28 https://doi.org/10.1001/jama.2013.108415
29 https://doi.org/10.1002/cncr.22408
30 https://doi.org/10.1002/cncr.23873
31 https://doi.org/10.1016/j.amjsurg.2004.06.037
32 https://doi.org/10.1016/j.breast.2014.01.013
33 https://doi.org/10.1016/j.clbc.2013.08.008
34 https://doi.org/10.1016/j.diii.2013.01.011
35 https://doi.org/10.1016/j.humpath.2006.08.008
36 https://doi.org/10.1016/j.humpath.2009.09.005
37 https://doi.org/10.1016/j.suronc.2009.08.002
38 https://doi.org/10.1053/j.sembd.2006.06.007
39 https://doi.org/10.1056/nejm198501173120303
40 https://doi.org/10.1097/00000478-199812000-00009
41 https://doi.org/10.1097/00000658-194502000-00009
42 https://doi.org/10.1097/00000658-197211000-00022
43 https://doi.org/10.1097/00125480-200305000-00001
44 https://doi.org/10.1097/01.pas.0000146013.76881.d9
45 https://doi.org/10.1097/01.pas.0000157295.93914.3b
46 https://doi.org/10.1097/01.pas.0000213368.41251.b9
47 https://doi.org/10.1097/pas.0b013e318161d1a5
48 https://doi.org/10.1097/pas.0b013e31819d0a4d
49 https://doi.org/10.1097/sla.0b013e318233523f
50 https://doi.org/10.1111/j.1365-2559.2010.03568.x
51 https://doi.org/10.1111/tbj.12039
52 https://doi.org/10.1309/ajcpldg6tt7vahph
53 https://doi.org/10.2214/ajr.11.7717
54 https://doi.org/10.5858/arpa.2012-0297-oa
55 https://doi.org/10.5858/arpa.2013-0763-ed
56 schema:datePublished 2015-05
57 schema:datePublishedReg 2015-05-01
58 schema:description Flat epithelial atypia of the breast commonly co-exists with atypical ductal hyperplasia, lobular neoplasia, and indolent forms of invasive carcinomas such as tubular carcinoma. Most patients with pure flat epithelial atypia on core biopsy undergo surgical excision to evaluate for carcinoma in the adjacent breast tissue. Studies to date have reported varying upgrade rates with most recommending follow-up excision. These studies have often lacked detailed radiographic correlation, central review by breast pathologists and information regarding the biology of the carcinomas identified upon excision. In this study, we report the frequency of upgrade to invasive carcinoma or ductal carcinoma in situ in excision specimens following a diagnosis of pure flat epithelial atypia on core biopsy. Radiographic correlation is performed for each case and grade/receptor status of detected carcinomas is reported. Seventy-three (73) core biopsies containing pure flat epithelial atypia were identified from our files, meeting inclusion criteria for the study. In the subsequent excision biopsies, five (7%) cases contained invasive carcinoma or ductal carcinoma in situ and seventeen (23%) contained atypical ductal hyperplasia or lobular neoplasia. All of the ductal carcinoma in situ cases with estrogen receptor results were estrogen receptor positive and intermediate grade. The invasive tumors were small (pT1a) hormone receptor-positive, HER2-negative, low-grade invasive ductal or tubular carcinomas with negative sentinel lymph-node biopsies. No upgrades were identified in the 14 patients who had all of their calcifications removed by the stereotactic core biopsy. Our rate of upgrade to carcinoma, once cases with discordant imaging are excluded, is at the lower end of the range reported in the literature. Given the low upgrade rate and indolent nature of the carcinomas associated with flat epithelial atypia, case management may be individualized based on clinical and radiographic findings. Excision may not be necessary for patients without remaining calcifications following core biopsy.
59 schema:genre research_article
60 schema:inLanguage en
61 schema:isAccessibleForFree true
62 schema:isPartOf N71a3c20ed4254e10868f339d06232679
63 Nd13de2c3c5f84600827a2359e741e478
64 sg:journal.1098208
65 schema:name Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies
66 schema:pagination 670
67 schema:productId N185de87d9d0a412ba05604e2b57f24e5
68 N2dd29dad9ffa4d048a8202d4148dbb54
69 N8d63dac09eae43f29ac6795541351e97
70 Ncd04e706af9f4ec5b10ea1c52979ef62
71 Nd2830fd13314436ea77083733b4a1e24
72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041068575
73 https://doi.org/10.1038/modpathol.2014.159
74 schema:sdDatePublished 2019-04-10T19:46
75 schema:sdLicense https://scigraph.springernature.com/explorer/license/
76 schema:sdPublisher Ndb50eb40ae294e6da99f0d77462e35a4
77 schema:url https://www.nature.com/articles/modpathol2014159
78 sgo:license sg:explorer/license/
79 sgo:sdDataset articles
80 rdf:type schema:ScholarlyArticle
81 N108af180495549c0b82cb6d6f701e6ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Aged
83 rdf:type schema:DefinedTerm
84 N17b01d9baf1443099e6dc5699b35863e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Precancerous Conditions
86 rdf:type schema:DefinedTerm
87 N185de87d9d0a412ba05604e2b57f24e5 schema:name readcube_id
88 schema:value c3a2e9ca71f692dd264c53ca7f231135900d37b82294a3f9e3a1d2b8956cae37
89 rdf:type schema:PropertyValue
90 N2363a23569bc4bd18121c4988668f760 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Breast
92 rdf:type schema:DefinedTerm
93 N2b3f042f3ca743e0878935f3dbda1124 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Middle Aged
95 rdf:type schema:DefinedTerm
96 N2daa8cad15df42828496c39b42b017f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Breast Neoplasms
98 rdf:type schema:DefinedTerm
99 N2dd29dad9ffa4d048a8202d4148dbb54 schema:name dimensions_id
100 schema:value pub.1041068575
101 rdf:type schema:PropertyValue
102 N5d7c72e5eb1248c3a5ae21fc2936c2c9 rdf:first sg:person.01177342226.34
103 rdf:rest Nd44b51b05dcb4d5b9ef21521162f23ee
104 N5d87bf7e1e1b41c38c7218a5c3104242 rdf:first sg:person.010252703435.01
105 rdf:rest Nb0513d30f8c44764a4b0bb4b585905ae
106 N608bfe0487004bc2ae93c5731c4e6f8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Biopsy, Large-Core Needle
108 rdf:type schema:DefinedTerm
109 N71a3c20ed4254e10868f339d06232679 schema:issueNumber 5
110 rdf:type schema:PublicationIssue
111 N77b149d3ac6c4d74a67f7f517aede07c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Humans
113 rdf:type schema:DefinedTerm
114 N8d63dac09eae43f29ac6795541351e97 schema:name nlm_unique_id
115 schema:value 8806605
116 rdf:type schema:PropertyValue
117 Nb0513d30f8c44764a4b0bb4b585905ae rdf:first sg:person.0616076375.13
118 rdf:rest N5d7c72e5eb1248c3a5ae21fc2936c2c9
119 Nb9459573350b44d9ab5c341994544a40 rdf:first sg:person.0770003170.62
120 rdf:rest Nec411ed94190467c8073ce8b02a800b1
121 Nbb306038069947a6ab7adeaecf8302d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Female
123 rdf:type schema:DefinedTerm
124 Ncd04e706af9f4ec5b10ea1c52979ef62 schema:name doi
125 schema:value 10.1038/modpathol.2014.159
126 rdf:type schema:PropertyValue
127 Nd13de2c3c5f84600827a2359e741e478 schema:volumeNumber 28
128 rdf:type schema:PublicationVolume
129 Nd2830fd13314436ea77083733b4a1e24 schema:name pubmed_id
130 schema:value 25412845
131 rdf:type schema:PropertyValue
132 Nd31d1cdfee654d6196fc67de232dfde1 rdf:first sg:person.010346216553.04
133 rdf:rest Nb9459573350b44d9ab5c341994544a40
134 Nd44b51b05dcb4d5b9ef21521162f23ee rdf:first Nf5716eaa00804024b6e11b9efb1b1bd3
135 rdf:rest Nd31d1cdfee654d6196fc67de232dfde1
136 Ndb50eb40ae294e6da99f0d77462e35a4 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 Nde785ee0c0bc405faf6e4ed19ec5afb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Adult
140 rdf:type schema:DefinedTerm
141 Nec411ed94190467c8073ce8b02a800b1 rdf:first sg:person.0707456700.38
142 rdf:rest rdf:nil
143 Nf13e8de9185a43d29004e0d7e07785b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Carcinoma
145 rdf:type schema:DefinedTerm
146 Nf5716eaa00804024b6e11b9efb1b1bd3 schema:affiliation https://www.grid.ac/institutes/grid.239494.1
147 schema:familyName Gromet
148 schema:givenName Matt
149 rdf:type schema:Person
150 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
151 schema:name Medical and Health Sciences
152 rdf:type schema:DefinedTerm
153 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
154 schema:name Oncology and Carcinogenesis
155 rdf:type schema:DefinedTerm
156 sg:journal.1098208 schema:issn 0893-3952
157 1530-0285
158 schema:name Modern Pathology
159 rdf:type schema:Periodical
160 sg:person.010252703435.01 schema:affiliation https://www.grid.ac/institutes/grid.468189.a
161 schema:familyName Calhoun
162 schema:givenName Benjamin C
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010252703435.01
164 rdf:type schema:Person
165 sg:person.010346216553.04 schema:affiliation https://www.grid.ac/institutes/grid.468189.a
166 schema:familyName Flippo
167 schema:givenName Teresa
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010346216553.04
169 rdf:type schema:Person
170 sg:person.01177342226.34 schema:affiliation https://www.grid.ac/institutes/grid.468189.a
171 schema:familyName White
172 schema:givenName Richard L
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177342226.34
174 rdf:type schema:Person
175 sg:person.0616076375.13 schema:affiliation https://www.grid.ac/institutes/grid.239494.1
176 schema:familyName Sobel
177 schema:givenName Amy
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616076375.13
179 rdf:type schema:Person
180 sg:person.0707456700.38 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
181 schema:familyName Livasy
182 schema:givenName Chad A
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707456700.38
184 rdf:type schema:Person
185 sg:person.0770003170.62 schema:affiliation https://www.grid.ac/institutes/grid.468189.a
186 schema:familyName Sarantou
187 schema:givenName Terry
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770003170.62
189 rdf:type schema:Person
190 sg:pub.10.1007/s00428-012-1279-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1038830976
191 https://doi.org/10.1007/s00428-012-1279-y
192 rdf:type schema:CreativeWork
193 sg:pub.10.1007/s00428-012-1312-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017132886
194 https://doi.org/10.1007/s00428-012-1312-1
195 rdf:type schema:CreativeWork
196 sg:pub.10.1007/s10549-010-1208-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051588964
197 https://doi.org/10.1007/s10549-010-1208-1
198 rdf:type schema:CreativeWork
199 sg:pub.10.1007/s10549-011-1839-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006502771
200 https://doi.org/10.1007/s10549-011-1839-x
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/modpathol.2009.21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023339482
203 https://doi.org/10.1038/modpathol.2009.21
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/modpathol.3800014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038084345
206 https://doi.org/10.1038/modpathol.3800014
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/modpathol.3800514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030437381
209 https://doi.org/10.1038/modpathol.3800514
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/ncponc0109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001904623
212 https://doi.org/10.1038/ncponc0109
213 rdf:type schema:CreativeWork
214 sg:pub.10.1097/01.mp.0000051930.68104.92 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020743244
215 https://doi.org/10.1097/01.mp.0000051930.68104.92
216 rdf:type schema:CreativeWork
217 sg:pub.10.1186/bcr1367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017738976
218 https://doi.org/10.1186/bcr1367
219 rdf:type schema:CreativeWork
220 sg:pub.10.1186/bcr2624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048726884
221 https://doi.org/10.1186/bcr2624
222 rdf:type schema:CreativeWork
223 sg:pub.10.1245/s10434-011-2034-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013038864
224 https://doi.org/10.1245/s10434-011-2034-3
225 rdf:type schema:CreativeWork
226 sg:pub.10.1245/s10434-012-2591-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025867608
227 https://doi.org/10.1245/s10434-012-2591-0
228 rdf:type schema:CreativeWork
229 sg:pub.10.1245/s10434-012-2846-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039782251
230 https://doi.org/10.1245/s10434-012-2846-9
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1001/jama.2013.108415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046777432
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/cncr.22408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007176956
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1002/cncr.23873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020366545
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/j.amjsurg.2004.06.037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027129322
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/j.breast.2014.01.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022540804
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.clbc.2013.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017035533
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.diii.2013.01.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010614467
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/j.humpath.2006.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011341289
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/j.humpath.2009.09.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046969801
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/j.suronc.2009.08.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008133091
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1053/j.sembd.2006.06.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019315768
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1056/nejm198501173120303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010245188
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1097/00000478-199812000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060122735
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/00000658-194502000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025664760
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/00000658-197211000-00022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006059513
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1097/00125480-200305000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042629803
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1097/01.pas.0000146013.76881.d9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046023790
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1097/01.pas.0000157295.93914.3b schema:sameAs https://app.dimensions.ai/details/publication/pub.1051639767
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1097/01.pas.0000213368.41251.b9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017049656
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1097/pas.0b013e318161d1a5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025042539
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1097/pas.0b013e31819d0a4d schema:sameAs https://app.dimensions.ai/details/publication/pub.1039318612
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1097/sla.0b013e318233523f schema:sameAs https://app.dimensions.ai/details/publication/pub.1023151898
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1111/j.1365-2559.2010.03568.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013071724
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1111/tbj.12039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034649428
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1309/ajcpldg6tt7vahph schema:sameAs https://app.dimensions.ai/details/publication/pub.1002200638
281 rdf:type schema:CreativeWork
282 https://doi.org/10.2214/ajr.11.7717 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069302092
283 rdf:type schema:CreativeWork
284 https://doi.org/10.5858/arpa.2012-0297-oa schema:sameAs https://app.dimensions.ai/details/publication/pub.1002595974
285 rdf:type schema:CreativeWork
286 https://doi.org/10.5858/arpa.2013-0763-ed schema:sameAs https://app.dimensions.ai/details/publication/pub.1032396075
287 rdf:type schema:CreativeWork
288 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
289 schema:name Carolinas Pathology Group, Levine Cancer Institute, Charlotte, NC, USA
290 Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
291 rdf:type schema:Organization
292 https://www.grid.ac/institutes/grid.239494.1 schema:alternateName Carolinas Medical Center
293 schema:name Charlotte Radiology, Carolinas Medical Center, Charlotte, NC, USA
294 rdf:type schema:Organization
295 https://www.grid.ac/institutes/grid.468189.a schema:alternateName Levine Cancer Institute
296 schema:name Carolinas Pathology Group, Levine Cancer Institute, Charlotte, NC, USA
297 Department of Surgery, Division of Surgical Oncology, Levine Cancer Institute, Charlotte, NC, USA
298 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...