Evaluation of microvascular density in Barrett’s associated neoplasia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-01

AUTHORS

Vani J A Konda, John Hart, Shang Lin, Maria Tretiakova, Ilyssa O Gordon, Lucas Campbell, Anirudh Kulkarni, Marc Bissonnette, Stefan Seewald, Irving Waxman

ABSTRACT

Angiogenesis has an important role in the carcinogenesis of esophageal adenocarcinoma, however, the diagnostic and prognostic utility of microvascular density counts have not been clinically established. The aim of this study is to assess the correlation between microvascular density and disease progression of non-dysplastic Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and invasive carcinoma in the superficial aspects of the tissue. Archival histological specimens from two referral centers for Barrett's esophagus and esophageal cancer were selected for review. A total of 160 regions marked according to histological grade were assessed with digitally interactive software to measure microvascular density. This was quantified in three levels: 0-50, 50-100 and 100-150 μm. In the areas of gastric cardia, Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and cancer, microvascular density was significantly different (P<0.0001) among the five groups in the most superficial 150 μm of the mucosa. Furthermore, when examining the pairwise difference between the groups, there was a significant difference between cancer and each of the lower grades of histology (P<0.05) and between high-grade dysplasia and each of the lower grades of histology (P<0.05). These statistically significant differences were preserved in examining the depth at the most superficial 50 μm. We have used digital pathology to demonstrate a significant and stepwise increase in microvascular density, which supports the hypothesis that angiogenesis has a key role in Barrett's carcinogenesis. Furthermore, the differences in the most superficial mucosal layers are consistent with findings of increased vascularity by depth-restricted imaging modalities. More... »

PAGES

125

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/modpathol.2012.146

DOI

http://dx.doi.org/10.1038/modpathol.2012.146

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015042399

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22918163


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Barrett Esophagus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Esophageal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microvessels", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neovascularization, Pathologic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Precancerous Conditions", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Center for Endoscopic Research and Therapeutics, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Konda", 
        "givenName": "Vani J A", 
        "id": "sg:person.016211107751.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016211107751.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hart", 
        "givenName": "John", 
        "id": "sg:person.0765605004.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765605004.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Health Studies, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Shang", 
        "id": "sg:person.01201250420.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201250420.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tretiakova", 
        "givenName": "Maria", 
        "id": "sg:person.0777063763.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777063763.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gordon", 
        "givenName": "Ilyssa O", 
        "id": "sg:person.01357170643.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357170643.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campbell", 
        "givenName": "Lucas", 
        "id": "sg:person.07500266133.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07500266133.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kulkarni", 
        "givenName": "Anirudh", 
        "id": "sg:person.011742014211.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011742014211.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Department of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bissonnette", 
        "givenName": "Marc", 
        "id": "sg:person.01274626215.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274626215.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Klinik Hirslanden", 
          "id": "https://www.grid.ac/institutes/grid.417546.5", 
          "name": [
            "Section of Gastroenterology, Klinik Hirslanden, Zurich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seewald", 
        "givenName": "Stefan", 
        "id": "sg:person.01357134332.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357134332.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chicago Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.412578.d", 
          "name": [
            "Center for Endoscopic Research and Therapeutics, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Waxman", 
        "givenName": "Irving", 
        "id": "sg:person.01330023502.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330023502.40"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1136/gut.2008.157461", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003224479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10620-011-1990-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016422044", 
          "https://doi.org/10.1007/s10620-011-1990-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mog.0b013e32833ad5c4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016439722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mog.0b013e32833ad5c4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016439722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mog.0b013e32833ad5c4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016439722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gie.2005.10.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016686873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cgh.2006.05.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019704244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2005.01.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028532517"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gie.2011.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029293287"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2003.07.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029850415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1746.2008.05440.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034119274"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbio.201100022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039320985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181d38f0a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039442353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181d38f0a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039442353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181d38f0a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039442353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mtc.2003.203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043799367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mtc.2003.203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043799367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-004-7286-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043901165", 
          "https://doi.org/10.1007/s00268-004-7286-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path709>3.0.co;2-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048207099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0046-8177(99)90135-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049859166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0030-1256632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057221581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2008-1077718", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057567841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2002.09.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203117"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-01", 
    "datePublishedReg": "2013-01-01", 
    "description": "Angiogenesis has an important role in the carcinogenesis of esophageal adenocarcinoma, however, the diagnostic and prognostic utility of microvascular density counts have not been clinically established. The aim of this study is to assess the correlation between microvascular density and disease progression of non-dysplastic Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and invasive carcinoma in the superficial aspects of the tissue. Archival histological specimens from two referral centers for Barrett's esophagus and esophageal cancer were selected for review. A total of 160 regions marked according to histological grade were assessed with digitally interactive software to measure microvascular density. This was quantified in three levels: 0-50, 50-100 and 100-150\u2009\u03bcm. In the areas of gastric cardia, Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and cancer, microvascular density was significantly different (P<0.0001) among the five groups in the most superficial 150\u2009\u03bcm of the mucosa. Furthermore, when examining the pairwise difference between the groups, there was a significant difference between cancer and each of the lower grades of histology (P<0.05) and between high-grade dysplasia and each of the lower grades of histology (P<0.05). These statistically significant differences were preserved in examining the depth at the most superficial 50\u2009\u03bcm. We have used digital pathology to demonstrate a significant and stepwise increase in microvascular density, which supports the hypothesis that angiogenesis has a key role in Barrett's carcinogenesis. Furthermore, the differences in the most superficial mucosal layers are consistent with findings of increased vascularity by depth-restricted imaging modalities.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/modpathol.2012.146", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1098208", 
        "issn": [
          "0893-3952", 
          "1530-0285"
        ], 
        "name": "Modern Pathology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "name": "Evaluation of microvascular density in Barrett\u2019s associated neoplasia", 
    "pagination": "125", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "47aada93a494c9872a8c294f2985c09691f0bf1c8c926846409588fedd806d3e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22918163"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8806605"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/modpathol.2012.146"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1015042399"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/modpathol.2012.146", 
      "https://app.dimensions.ai/details/publication/pub.1015042399"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000436.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/modpathol2012146"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2012.146'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2012.146'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2012.146'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/modpathol.2012.146'


 

This table displays all metadata directly associated to this object as RDF triples.

226 TRIPLES      21 PREDICATES      55 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/modpathol.2012.146 schema:about N23fc74c86c64447aaf993431bfeb6445
2 N3238314cb0ae47ec8cccc77ac2e7f366
3 N4d0fe04e447c43a58b331dc524c96c42
4 N89590abb292b4830bfb29629351fd39c
5 Na3ce28125b324f6b8e8d2012c86ec144
6 Nc037ede5c74942649ab0d24e406f19f1
7 Nc66563b918624e1fac150fe397bb54ec
8 Nf10ee6e34a5c4ab38a9fdc6c535fa1a3
9 anzsrc-for:11
10 anzsrc-for:1103
11 schema:author Nbbd764031e8a407eb7aafaa4a3e66191
12 schema:citation sg:pub.10.1007/s00268-004-7286-7
13 sg:pub.10.1007/s10620-011-1990-6
14 https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path709>3.0.co;2-f
15 https://doi.org/10.1002/jbio.201100022
16 https://doi.org/10.1016/j.cgh.2006.05.010
17 https://doi.org/10.1016/j.ejso.2003.07.002
18 https://doi.org/10.1016/j.ejso.2005.01.006
19 https://doi.org/10.1016/j.gie.2005.10.044
20 https://doi.org/10.1016/j.gie.2011.04.004
21 https://doi.org/10.1016/s0046-8177(99)90135-1
22 https://doi.org/10.1055/s-0030-1256632
23 https://doi.org/10.1055/s-2008-1077718
24 https://doi.org/10.1067/mtc.2003.203
25 https://doi.org/10.1097/mog.0b013e32833ad5c4
26 https://doi.org/10.1097/pas.0b013e3181d38f0a
27 https://doi.org/10.1111/j.1440-1746.2008.05440.x
28 https://doi.org/10.1136/gut.2008.157461
29 https://doi.org/10.1200/jco.2002.09.011
30 schema:datePublished 2013-01
31 schema:datePublishedReg 2013-01-01
32 schema:description Angiogenesis has an important role in the carcinogenesis of esophageal adenocarcinoma, however, the diagnostic and prognostic utility of microvascular density counts have not been clinically established. The aim of this study is to assess the correlation between microvascular density and disease progression of non-dysplastic Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and invasive carcinoma in the superficial aspects of the tissue. Archival histological specimens from two referral centers for Barrett's esophagus and esophageal cancer were selected for review. A total of 160 regions marked according to histological grade were assessed with digitally interactive software to measure microvascular density. This was quantified in three levels: 0-50, 50-100 and 100-150 μm. In the areas of gastric cardia, Barrett's esophagus, low-grade dysplasia, high-grade dysplasia and cancer, microvascular density was significantly different (P<0.0001) among the five groups in the most superficial 150 μm of the mucosa. Furthermore, when examining the pairwise difference between the groups, there was a significant difference between cancer and each of the lower grades of histology (P<0.05) and between high-grade dysplasia and each of the lower grades of histology (P<0.05). These statistically significant differences were preserved in examining the depth at the most superficial 50 μm. We have used digital pathology to demonstrate a significant and stepwise increase in microvascular density, which supports the hypothesis that angiogenesis has a key role in Barrett's carcinogenesis. Furthermore, the differences in the most superficial mucosal layers are consistent with findings of increased vascularity by depth-restricted imaging modalities.
33 schema:genre research_article
34 schema:inLanguage en
35 schema:isAccessibleForFree true
36 schema:isPartOf Ne00d58ebc0404eed82fd4586b84a878d
37 Nf1a62f78043144fbb11d35d5e11267ae
38 sg:journal.1098208
39 schema:name Evaluation of microvascular density in Barrett’s associated neoplasia
40 schema:pagination 125
41 schema:productId N1cf112f248a543be8831b14006b0e848
42 N6523c04d064f46868d51afb7422b3786
43 Nb7adaef59d864a4192d514978a356254
44 Nbbb4941fd2de41829aeb6385cdaa89ce
45 Nbea8b246a5e9426894799805af2381e9
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015042399
47 https://doi.org/10.1038/modpathol.2012.146
48 schema:sdDatePublished 2019-04-10T17:20
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher N4d81dcc3b9144e61bbe6c96763df25ea
51 schema:url https://www.nature.com/articles/modpathol2012146
52 sgo:license sg:explorer/license/
53 sgo:sdDataset articles
54 rdf:type schema:ScholarlyArticle
55 N1cf112f248a543be8831b14006b0e848 schema:name pubmed_id
56 schema:value 22918163
57 rdf:type schema:PropertyValue
58 N23fc74c86c64447aaf993431bfeb6445 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
59 schema:name Neovascularization, Pathologic
60 rdf:type schema:DefinedTerm
61 N3238314cb0ae47ec8cccc77ac2e7f366 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Esophageal Neoplasms
63 rdf:type schema:DefinedTerm
64 N4b3f55ca156f43cd88a77a94a625616b rdf:first sg:person.01201250420.67
65 rdf:rest N5ef90cd6ec834a39a9140efd9a7bc6f5
66 N4d0fe04e447c43a58b331dc524c96c42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Humans
68 rdf:type schema:DefinedTerm
69 N4d81dcc3b9144e61bbe6c96763df25ea schema:name Springer Nature - SN SciGraph project
70 rdf:type schema:Organization
71 N5ef90cd6ec834a39a9140efd9a7bc6f5 rdf:first sg:person.0777063763.37
72 rdf:rest Nad51fea3e6d544f781686129f2ecd3ab
73 N62639ce173ec4f44aed04b6db0da3f1c rdf:first sg:person.07500266133.73
74 rdf:rest Nd3e23c7f8dc143dabbd1b95206de6600
75 N6523c04d064f46868d51afb7422b3786 schema:name nlm_unique_id
76 schema:value 8806605
77 rdf:type schema:PropertyValue
78 N70dedcdf9897468d8781c843f31da464 rdf:first sg:person.01330023502.40
79 rdf:rest rdf:nil
80 N89590abb292b4830bfb29629351fd39c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Carcinoma
82 rdf:type schema:DefinedTerm
83 N9b93cd3312be42c79804f8dba2172210 rdf:first sg:person.01274626215.06
84 rdf:rest Nf1207f3bd3ee421690443ff413fb574f
85 Na3ce28125b324f6b8e8d2012c86ec144 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Disease Progression
87 rdf:type schema:DefinedTerm
88 Nad51fea3e6d544f781686129f2ecd3ab rdf:first sg:person.01357170643.35
89 rdf:rest N62639ce173ec4f44aed04b6db0da3f1c
90 Nb7adaef59d864a4192d514978a356254 schema:name doi
91 schema:value 10.1038/modpathol.2012.146
92 rdf:type schema:PropertyValue
93 Nbbb4941fd2de41829aeb6385cdaa89ce schema:name readcube_id
94 schema:value 47aada93a494c9872a8c294f2985c09691f0bf1c8c926846409588fedd806d3e
95 rdf:type schema:PropertyValue
96 Nbbd764031e8a407eb7aafaa4a3e66191 rdf:first sg:person.016211107751.32
97 rdf:rest Nde11fe204143435aab29dbac8c06c2f8
98 Nbea8b246a5e9426894799805af2381e9 schema:name dimensions_id
99 schema:value pub.1015042399
100 rdf:type schema:PropertyValue
101 Nc037ede5c74942649ab0d24e406f19f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Barrett Esophagus
103 rdf:type schema:DefinedTerm
104 Nc66563b918624e1fac150fe397bb54ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Microvessels
106 rdf:type schema:DefinedTerm
107 Nd3e23c7f8dc143dabbd1b95206de6600 rdf:first sg:person.011742014211.47
108 rdf:rest N9b93cd3312be42c79804f8dba2172210
109 Nde11fe204143435aab29dbac8c06c2f8 rdf:first sg:person.0765605004.87
110 rdf:rest N4b3f55ca156f43cd88a77a94a625616b
111 Ne00d58ebc0404eed82fd4586b84a878d schema:issueNumber 1
112 rdf:type schema:PublicationIssue
113 Nf10ee6e34a5c4ab38a9fdc6c535fa1a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Precancerous Conditions
115 rdf:type schema:DefinedTerm
116 Nf1207f3bd3ee421690443ff413fb574f rdf:first sg:person.01357134332.00
117 rdf:rest N70dedcdf9897468d8781c843f31da464
118 Nf1a62f78043144fbb11d35d5e11267ae schema:volumeNumber 26
119 rdf:type schema:PublicationVolume
120 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
121 schema:name Medical and Health Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
124 schema:name Clinical Sciences
125 rdf:type schema:DefinedTerm
126 sg:journal.1098208 schema:issn 0893-3952
127 1530-0285
128 schema:name Modern Pathology
129 rdf:type schema:Periodical
130 sg:person.011742014211.47 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
131 schema:familyName Kulkarni
132 schema:givenName Anirudh
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011742014211.47
134 rdf:type schema:Person
135 sg:person.01201250420.67 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
136 schema:familyName Lin
137 schema:givenName Shang
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201250420.67
139 rdf:type schema:Person
140 sg:person.01274626215.06 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
141 schema:familyName Bissonnette
142 schema:givenName Marc
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274626215.06
144 rdf:type schema:Person
145 sg:person.01330023502.40 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
146 schema:familyName Waxman
147 schema:givenName Irving
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330023502.40
149 rdf:type schema:Person
150 sg:person.01357134332.00 schema:affiliation https://www.grid.ac/institutes/grid.417546.5
151 schema:familyName Seewald
152 schema:givenName Stefan
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357134332.00
154 rdf:type schema:Person
155 sg:person.01357170643.35 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
156 schema:familyName Gordon
157 schema:givenName Ilyssa O
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357170643.35
159 rdf:type schema:Person
160 sg:person.016211107751.32 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
161 schema:familyName Konda
162 schema:givenName Vani J A
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016211107751.32
164 rdf:type schema:Person
165 sg:person.07500266133.73 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
166 schema:familyName Campbell
167 schema:givenName Lucas
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07500266133.73
169 rdf:type schema:Person
170 sg:person.0765605004.87 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
171 schema:familyName Hart
172 schema:givenName John
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765605004.87
174 rdf:type schema:Person
175 sg:person.0777063763.37 schema:affiliation https://www.grid.ac/institutes/grid.412578.d
176 schema:familyName Tretiakova
177 schema:givenName Maria
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777063763.37
179 rdf:type schema:Person
180 sg:pub.10.1007/s00268-004-7286-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043901165
181 https://doi.org/10.1007/s00268-004-7286-7
182 rdf:type schema:CreativeWork
183 sg:pub.10.1007/s10620-011-1990-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016422044
184 https://doi.org/10.1007/s10620-011-1990-6
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path709>3.0.co;2-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1048207099
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1002/jbio.201100022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039320985
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.cgh.2006.05.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019704244
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/j.ejso.2003.07.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029850415
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/j.ejso.2005.01.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028532517
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.gie.2005.10.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016686873
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.gie.2011.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029293287
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/s0046-8177(99)90135-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049859166
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1055/s-0030-1256632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057221581
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1055/s-2008-1077718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057567841
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1067/mtc.2003.203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043799367
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1097/mog.0b013e32833ad5c4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016439722
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1097/pas.0b013e3181d38f0a schema:sameAs https://app.dimensions.ai/details/publication/pub.1039442353
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1111/j.1440-1746.2008.05440.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034119274
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1136/gut.2008.157461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003224479
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1200/jco.2002.09.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203117
217 rdf:type schema:CreativeWork
218 https://www.grid.ac/institutes/grid.412578.d schema:alternateName University of Chicago Medical Center
219 schema:name Center for Endoscopic Research and Therapeutics, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA
220 Department of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA
221 Department of Health Studies, University of Chicago Medical Center, Chicago, IL, USA
222 Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA
223 rdf:type schema:Organization
224 https://www.grid.ac/institutes/grid.417546.5 schema:alternateName Klinik Hirslanden
225 schema:name Section of Gastroenterology, Klinik Hirslanden, Zurich, Switzerland
226 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...