Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-04

AUTHORS

Jai-Hyun Kim, Tomasz Tuziak, Limei Hu, Zhi Wang, Jolanta Bondaruk, MiSook Kim, Gregory Fuller, Colin Dinney, Herbert Barton Grossman, Keith Baggerly, Wei Zhang, Bogdan Czerniak

ABSTRACT

Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival. More... »

PAGES

532

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/labinvest.3700250

DOI

http://dx.doi.org/10.1038/labinvest.3700250

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017472931

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15778693


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Complementary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multigene Family", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotide Array Sequence Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reverse Transcriptase Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Bladder Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Jai-Hyun", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tuziak", 
        "givenName": "Tomasz", 
        "id": "sg:person.01175340240.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175340240.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Limei", 
        "id": "sg:person.016205341247.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016205341247.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Zhi", 
        "id": "sg:person.0702713543.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702713543.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bondaruk", 
        "givenName": "Jolanta", 
        "id": "sg:person.0737211130.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737211130.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "MiSook", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuller", 
        "givenName": "Gregory", 
        "id": "sg:person.013732343337.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732343337.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dinney", 
        "givenName": "Colin", 
        "id": "sg:person.012610632077.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012610632077.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grossman", 
        "givenName": "Herbert Barton", 
        "id": "sg:person.01020612040.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020612040.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Biostatistics and Applied Mathematics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baggerly", 
        "givenName": "Keith", 
        "id": "sg:person.0731747000.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731747000.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Wei", 
        "id": "sg:person.012724545020.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012724545020.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Czerniak", 
        "givenName": "Bogdan", 
        "id": "sg:person.0635271651.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635271651.60"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.onc.1204612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000444160", 
          "https://doi.org/10.1038/sj.onc.1204612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1204612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000444160", 
          "https://doi.org/10.1038/sj.onc.1204612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001246428", 
          "https://doi.org/10.1038/sj.onc.1201044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001246428", 
          "https://doi.org/10.1038/sj.onc.1201044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/canjclin.54.1.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001408630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-03-3620", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005461901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.03.118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006309480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1750-3639.2002.tb00426.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006415372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1007403503", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-59871-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007403503", 
          "https://doi.org/10.1007/978-3-642-59871-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-59871-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007403503", 
          "https://doi.org/10.1007/978-3-642-59871-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/94.17.1320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009989679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcb.240501314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010918080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcb.240501314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010918080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0046-8177(92)90285-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011295893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/93.6.413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011728937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-4295(77)90227-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016061438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.12.994", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016348735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018653167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5347(05)63991-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021735475"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024660747", 
          "https://doi.org/10.1038/sj.onc.1202385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024660747", 
          "https://doi.org/10.1038/sj.onc.1202385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.20204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025558586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/29.4.6166661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029463505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/29.4.6166661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029463505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/300149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038315851", 
          "https://doi.org/10.1038/300149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.3780315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041334550", 
          "https://doi.org/10.1038/labinvest.3780315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.3780315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041334550", 
          "https://doi.org/10.1038/labinvest.3780315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.20095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041460872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199101103240211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043838552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.11778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044745311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044852770", 
          "https://doi.org/10.1038/ng1061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044852770", 
          "https://doi.org/10.1038/ng1061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1974.03230160009002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045610845"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(01)00968-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051113271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.227.3.281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054130555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/106652701753307539", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059204913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2144/01311st01", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074852712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074880622", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074993564", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075019600", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075198249", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075214729", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083119795", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083232606", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083251764", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083360550", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-04", 
    "datePublishedReg": "2005-04-01", 
    "description": "Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/labinvest.3700250", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2626451", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2472268", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2440171", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2688897", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1017964", 
        "issn": [
          "0023-6837", 
          "1530-0307"
        ], 
        "name": "Laboratory Investigation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "85"
      }
    ], 
    "name": "Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways", 
    "pagination": "532", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "533f6050ec65b2bc51369053f64ac8b199dfbcce8d739288e188137aa58d8bae"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15778693"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0376617"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/labinvest.3700250"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1017472931"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/labinvest.3700250", 
      "https://app.dimensions.ai/details/publication/pub.1017472931"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78934_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/3700250"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'


 

This table displays all metadata directly associated to this object as RDF triples.

303 TRIPLES      21 PREDICATES      77 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/labinvest.3700250 schema:about N3894c1b3ef7649a0afb44d333d499b80
2 N39b36ac52c3c4318959365f61112ed18
3 N4c1aa5a05c3348e384708ac240ceec45
4 N79013efca7a2461484d7acc166615a00
5 N7ed2640843564510a7e6f20ae405acfc
6 Na14b28ecac5a4c2a835a5bd8dc3073bb
7 Ncf94afcfe96b483f83d66807a5a4da00
8 Nd160df44685749a094b9979314b02dd8
9 anzsrc-for:11
10 anzsrc-for:1112
11 schema:author Nb96e0c60445543ed871ec3a23471723f
12 schema:citation sg:pub.10.1007/978-3-642-59871-5
13 sg:pub.10.1038/300149a0
14 sg:pub.10.1038/labinvest.3780315
15 sg:pub.10.1038/ng1061
16 sg:pub.10.1038/sj.onc.1201044
17 sg:pub.10.1038/sj.onc.1202385
18 sg:pub.10.1038/sj.onc.1204612
19 https://app.dimensions.ai/details/publication/pub.1007403503
20 https://app.dimensions.ai/details/publication/pub.1074880622
21 https://app.dimensions.ai/details/publication/pub.1074993564
22 https://app.dimensions.ai/details/publication/pub.1075019600
23 https://app.dimensions.ai/details/publication/pub.1075198249
24 https://app.dimensions.ai/details/publication/pub.1075214729
25 https://app.dimensions.ai/details/publication/pub.1083119795
26 https://app.dimensions.ai/details/publication/pub.1083232606
27 https://app.dimensions.ai/details/publication/pub.1083251764
28 https://app.dimensions.ai/details/publication/pub.1083360550
29 https://doi.org/10.1001/jama.1974.03230160009002
30 https://doi.org/10.1001/jama.227.3.281
31 https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n
32 https://doi.org/10.1002/cncr.11778
33 https://doi.org/10.1002/cncr.20095
34 https://doi.org/10.1002/ijc.20204
35 https://doi.org/10.1002/jcb.240501314
36 https://doi.org/10.1016/0046-8177(92)90285-b
37 https://doi.org/10.1016/0090-4295(77)90227-8
38 https://doi.org/10.1016/s0022-5347(05)63991-2
39 https://doi.org/10.1016/s0090-4295(01)00968-2
40 https://doi.org/10.1056/nejm199101103240211
41 https://doi.org/10.1089/106652701753307539
42 https://doi.org/10.1093/jnci/93.6.413
43 https://doi.org/10.1093/jnci/94.17.1320
44 https://doi.org/10.1097/00005392-199902000-00106
45 https://doi.org/10.1111/j.1750-3639.2002.tb00426.x
46 https://doi.org/10.1158/0008-5472.can-03-3620
47 https://doi.org/10.1177/29.4.6166661
48 https://doi.org/10.1200/jco.2004.03.118
49 https://doi.org/10.1200/jco.2004.12.994
50 https://doi.org/10.2144/01311st01
51 https://doi.org/10.3322/canjclin.54.1.8
52 schema:datePublished 2005-04
53 schema:datePublishedReg 2005-04-01
54 schema:description Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival.
55 schema:genre research_article
56 schema:inLanguage en
57 schema:isAccessibleForFree true
58 schema:isPartOf Nd7ff1589ce7b4abf9114c4138dcbffef
59 Nf1c636e057e841dca5d107393f56d4a5
60 sg:journal.1017964
61 schema:name Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways
62 schema:pagination 532
63 schema:productId N0a5f61b440ee49d085d613e0edd98af2
64 N5e67b82af8c94b2d8923f15173c3f8ce
65 N5fe9fd92bb504706ac0074e4438cca62
66 Nb205c0a0a90942589742d2fdbaf7313d
67 Nfc3186d2e93d4040bb8f78355a58b21d
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017472931
69 https://doi.org/10.1038/labinvest.3700250
70 schema:sdDatePublished 2019-04-11T13:17
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher Nf92984fbb71b4e518f792151659462a8
73 schema:url https://www.nature.com/articles/3700250
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N0a5f61b440ee49d085d613e0edd98af2 schema:name readcube_id
78 schema:value 533f6050ec65b2bc51369053f64ac8b199dfbcce8d739288e188137aa58d8bae
79 rdf:type schema:PropertyValue
80 N0db8f0323e4242b39be698afbccc1757 rdf:first sg:person.0731747000.61
81 rdf:rest N77d67fedc5de44d38ac8d1faddf5fecc
82 N1024d080b476491e986dfeb26d3c4c91 rdf:first sg:person.0635271651.60
83 rdf:rest rdf:nil
84 N3894c1b3ef7649a0afb44d333d499b80 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Transcription, Genetic
86 rdf:type schema:DefinedTerm
87 N39b36ac52c3c4318959365f61112ed18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Reverse Transcriptase Polymerase Chain Reaction
89 rdf:type schema:DefinedTerm
90 N40ccde8d376449a797e69ed0fdeed17b rdf:first sg:person.01175340240.51
91 rdf:rest Nc99d0e40f2f94ea9b376cc4edec4e87b
92 N4508f85996834b40bf784db84c3a0682 rdf:first sg:person.013732343337.08
93 rdf:rest Nee1c02eb503f4fdbb9c72ffa66f0d676
94 N4c1aa5a05c3348e384708ac240ceec45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Immunohistochemistry
96 rdf:type schema:DefinedTerm
97 N5e67b82af8c94b2d8923f15173c3f8ce schema:name pubmed_id
98 schema:value 15778693
99 rdf:type schema:PropertyValue
100 N5fe9fd92bb504706ac0074e4438cca62 schema:name nlm_unique_id
101 schema:value 0376617
102 rdf:type schema:PropertyValue
103 N77d67fedc5de44d38ac8d1faddf5fecc rdf:first sg:person.012724545020.23
104 rdf:rest N1024d080b476491e986dfeb26d3c4c91
105 N79013efca7a2461484d7acc166615a00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name DNA, Complementary
107 rdf:type schema:DefinedTerm
108 N7ed2640843564510a7e6f20ae405acfc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Urinary Bladder Neoplasms
110 rdf:type schema:DefinedTerm
111 N869c53d84a184ec2a4568377ef722b7f rdf:first sg:person.0737211130.77
112 rdf:rest Nc187c8edb7d6433fb49628d979996398
113 Na14b28ecac5a4c2a835a5bd8dc3073bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Humans
115 rdf:type schema:DefinedTerm
116 Na77c890de8a64f9b8e47bd1b783c7f29 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
117 schema:familyName Kim
118 schema:givenName Jai-Hyun
119 rdf:type schema:Person
120 Naacdde3bb03a4de4879d70151f275a65 rdf:first sg:person.01020612040.52
121 rdf:rest N0db8f0323e4242b39be698afbccc1757
122 Nb205c0a0a90942589742d2fdbaf7313d schema:name dimensions_id
123 schema:value pub.1017472931
124 rdf:type schema:PropertyValue
125 Nb96e0c60445543ed871ec3a23471723f rdf:first Na77c890de8a64f9b8e47bd1b783c7f29
126 rdf:rest N40ccde8d376449a797e69ed0fdeed17b
127 Nc187c8edb7d6433fb49628d979996398 rdf:first Ncba96a60175b41cd97c7019daf65fc81
128 rdf:rest N4508f85996834b40bf784db84c3a0682
129 Nc99d0e40f2f94ea9b376cc4edec4e87b rdf:first sg:person.016205341247.35
130 rdf:rest Nf718b8caeb08495f9d180bc95a7cd88d
131 Ncba96a60175b41cd97c7019daf65fc81 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
132 schema:familyName Kim
133 schema:givenName MiSook
134 rdf:type schema:Person
135 Ncf94afcfe96b483f83d66807a5a4da00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Multigene Family
137 rdf:type schema:DefinedTerm
138 Nd160df44685749a094b9979314b02dd8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Oligonucleotide Array Sequence Analysis
140 rdf:type schema:DefinedTerm
141 Nd7ff1589ce7b4abf9114c4138dcbffef schema:volumeNumber 85
142 rdf:type schema:PublicationVolume
143 Nee1c02eb503f4fdbb9c72ffa66f0d676 rdf:first sg:person.012610632077.22
144 rdf:rest Naacdde3bb03a4de4879d70151f275a65
145 Nf1c636e057e841dca5d107393f56d4a5 schema:issueNumber 4
146 rdf:type schema:PublicationIssue
147 Nf718b8caeb08495f9d180bc95a7cd88d rdf:first sg:person.0702713543.67
148 rdf:rest N869c53d84a184ec2a4568377ef722b7f
149 Nf92984fbb71b4e518f792151659462a8 schema:name Springer Nature - SN SciGraph project
150 rdf:type schema:Organization
151 Nfc3186d2e93d4040bb8f78355a58b21d schema:name doi
152 schema:value 10.1038/labinvest.3700250
153 rdf:type schema:PropertyValue
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
158 schema:name Oncology and Carcinogenesis
159 rdf:type schema:DefinedTerm
160 sg:grant.2440171 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
161 rdf:type schema:MonetaryGrant
162 sg:grant.2472268 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
163 rdf:type schema:MonetaryGrant
164 sg:grant.2626451 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
165 rdf:type schema:MonetaryGrant
166 sg:grant.2688897 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
167 rdf:type schema:MonetaryGrant
168 sg:journal.1017964 schema:issn 0023-6837
169 1530-0307
170 schema:name Laboratory Investigation
171 rdf:type schema:Periodical
172 sg:person.01020612040.52 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
173 schema:familyName Grossman
174 schema:givenName Herbert Barton
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020612040.52
176 rdf:type schema:Person
177 sg:person.01175340240.51 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
178 schema:familyName Tuziak
179 schema:givenName Tomasz
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175340240.51
181 rdf:type schema:Person
182 sg:person.012610632077.22 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
183 schema:familyName Dinney
184 schema:givenName Colin
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012610632077.22
186 rdf:type schema:Person
187 sg:person.012724545020.23 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
188 schema:familyName Zhang
189 schema:givenName Wei
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012724545020.23
191 rdf:type schema:Person
192 sg:person.013732343337.08 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
193 schema:familyName Fuller
194 schema:givenName Gregory
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732343337.08
196 rdf:type schema:Person
197 sg:person.016205341247.35 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
198 schema:familyName Hu
199 schema:givenName Limei
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016205341247.35
201 rdf:type schema:Person
202 sg:person.0635271651.60 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
203 schema:familyName Czerniak
204 schema:givenName Bogdan
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635271651.60
206 rdf:type schema:Person
207 sg:person.0702713543.67 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
208 schema:familyName Wang
209 schema:givenName Zhi
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702713543.67
211 rdf:type schema:Person
212 sg:person.0731747000.61 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
213 schema:familyName Baggerly
214 schema:givenName Keith
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731747000.61
216 rdf:type schema:Person
217 sg:person.0737211130.77 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
218 schema:familyName Bondaruk
219 schema:givenName Jolanta
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737211130.77
221 rdf:type schema:Person
222 sg:pub.10.1007/978-3-642-59871-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007403503
223 https://doi.org/10.1007/978-3-642-59871-5
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/300149a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038315851
226 https://doi.org/10.1038/300149a0
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/labinvest.3780315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041334550
229 https://doi.org/10.1038/labinvest.3780315
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/ng1061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044852770
232 https://doi.org/10.1038/ng1061
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/sj.onc.1201044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001246428
235 https://doi.org/10.1038/sj.onc.1201044
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/sj.onc.1202385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024660747
238 https://doi.org/10.1038/sj.onc.1202385
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/sj.onc.1204612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000444160
241 https://doi.org/10.1038/sj.onc.1204612
242 rdf:type schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1007403503 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1074880622 schema:CreativeWork
245 https://app.dimensions.ai/details/publication/pub.1074993564 schema:CreativeWork
246 https://app.dimensions.ai/details/publication/pub.1075019600 schema:CreativeWork
247 https://app.dimensions.ai/details/publication/pub.1075198249 schema:CreativeWork
248 https://app.dimensions.ai/details/publication/pub.1075214729 schema:CreativeWork
249 https://app.dimensions.ai/details/publication/pub.1083119795 schema:CreativeWork
250 https://app.dimensions.ai/details/publication/pub.1083232606 schema:CreativeWork
251 https://app.dimensions.ai/details/publication/pub.1083251764 schema:CreativeWork
252 https://app.dimensions.ai/details/publication/pub.1083360550 schema:CreativeWork
253 https://doi.org/10.1001/jama.1974.03230160009002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045610845
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1001/jama.227.3.281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054130555
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n schema:sameAs https://app.dimensions.ai/details/publication/pub.1018653167
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1002/cncr.11778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044745311
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1002/cncr.20095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041460872
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1002/ijc.20204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025558586
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1002/jcb.240501314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010918080
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/0046-8177(92)90285-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1011295893
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/0090-4295(77)90227-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016061438
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0022-5347(05)63991-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021735475
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/s0090-4295(01)00968-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051113271
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1056/nejm199101103240211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043838552
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1089/106652701753307539 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059204913
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1093/jnci/93.6.413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011728937
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1093/jnci/94.17.1320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009989679
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1097/00005392-199902000-00106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060216290
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1111/j.1750-3639.2002.tb00426.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006415372
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1158/0008-5472.can-03-3620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005461901
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1177/29.4.6166661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029463505
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1200/jco.2004.03.118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006309480
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1200/jco.2004.12.994 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016348735
294 rdf:type schema:CreativeWork
295 https://doi.org/10.2144/01311st01 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074852712
296 rdf:type schema:CreativeWork
297 https://doi.org/10.3322/canjclin.54.1.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001408630
298 rdf:type schema:CreativeWork
299 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
300 schema:name Department of Biostatistics and Applied Mathematics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
301 Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
302 Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
303 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...