Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-04

AUTHORS

Jai-Hyun Kim, Tomasz Tuziak, Limei Hu, Zhi Wang, Jolanta Bondaruk, MiSook Kim, Gregory Fuller, Colin Dinney, Herbert Barton Grossman, Keith Baggerly, Wei Zhang, Bogdan Czerniak

ABSTRACT

Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival. More... »

PAGES

532

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/labinvest.3700250

DOI

http://dx.doi.org/10.1038/labinvest.3700250

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017472931

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15778693


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Complementary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multigene Family", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotide Array Sequence Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reverse Transcriptase Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Bladder Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Jai-Hyun", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tuziak", 
        "givenName": "Tomasz", 
        "id": "sg:person.01175340240.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175340240.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Limei", 
        "id": "sg:person.016205341247.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016205341247.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Zhi", 
        "id": "sg:person.0702713543.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702713543.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bondaruk", 
        "givenName": "Jolanta", 
        "id": "sg:person.0737211130.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737211130.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "MiSook", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuller", 
        "givenName": "Gregory", 
        "id": "sg:person.013732343337.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732343337.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dinney", 
        "givenName": "Colin", 
        "id": "sg:person.012610632077.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012610632077.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grossman", 
        "givenName": "Herbert Barton", 
        "id": "sg:person.01020612040.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020612040.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Biostatistics and Applied Mathematics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baggerly", 
        "givenName": "Keith", 
        "id": "sg:person.0731747000.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731747000.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Wei", 
        "id": "sg:person.012724545020.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012724545020.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Czerniak", 
        "givenName": "Bogdan", 
        "id": "sg:person.0635271651.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635271651.60"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.onc.1204612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000444160", 
          "https://doi.org/10.1038/sj.onc.1204612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1204612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000444160", 
          "https://doi.org/10.1038/sj.onc.1204612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001246428", 
          "https://doi.org/10.1038/sj.onc.1201044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001246428", 
          "https://doi.org/10.1038/sj.onc.1201044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/canjclin.54.1.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001408630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-03-3620", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005461901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.03.118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006309480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1750-3639.2002.tb00426.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006415372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1007403503", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-59871-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007403503", 
          "https://doi.org/10.1007/978-3-642-59871-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-59871-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007403503", 
          "https://doi.org/10.1007/978-3-642-59871-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/94.17.1320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009989679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcb.240501314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010918080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcb.240501314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010918080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0046-8177(92)90285-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011295893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/93.6.413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011728937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-4295(77)90227-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016061438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.12.994", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016348735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018653167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5347(05)63991-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021735475"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024660747", 
          "https://doi.org/10.1038/sj.onc.1202385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024660747", 
          "https://doi.org/10.1038/sj.onc.1202385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.20204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025558586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/29.4.6166661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029463505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/29.4.6166661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029463505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/300149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038315851", 
          "https://doi.org/10.1038/300149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.3780315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041334550", 
          "https://doi.org/10.1038/labinvest.3780315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.3780315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041334550", 
          "https://doi.org/10.1038/labinvest.3780315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.20095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041460872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199101103240211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043838552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.11778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044745311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044852770", 
          "https://doi.org/10.1038/ng1061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044852770", 
          "https://doi.org/10.1038/ng1061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1974.03230160009002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045610845"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(01)00968-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051113271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.227.3.281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054130555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/106652701753307539", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059204913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005392-199902000-00106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060216290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2144/01311st01", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074852712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074880622", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074993564", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075019600", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075198249", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075214729", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083119795", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083232606", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083251764", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083360550", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-04", 
    "datePublishedReg": "2005-04-01", 
    "description": "Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/labinvest.3700250", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2626451", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2472268", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2440171", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2688897", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1017964", 
        "issn": [
          "0023-6837", 
          "1530-0307"
        ], 
        "name": "Laboratory Investigation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "85"
      }
    ], 
    "name": "Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways", 
    "pagination": "532", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "533f6050ec65b2bc51369053f64ac8b199dfbcce8d739288e188137aa58d8bae"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15778693"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0376617"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/labinvest.3700250"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1017472931"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/labinvest.3700250", 
      "https://app.dimensions.ai/details/publication/pub.1017472931"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78934_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/3700250"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/labinvest.3700250'


 

This table displays all metadata directly associated to this object as RDF triples.

303 TRIPLES      21 PREDICATES      77 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/labinvest.3700250 schema:about N060abc64dc25477c9c4e9f1cf82fcc94
2 N1e9c7290292a40e2a8d92535ff61d608
3 N2a5600f9c37c47cca80bf681a6bc6f4e
4 N616ca1565fe5481baf5baa681dadf029
5 Na66ecf653da1461fbcf2680ea413f5e6
6 Nb14b10122a3b4bda98bc316cc6fc3d04
7 Nd3f6b764d8dc4182a5ba39eff15f6af7
8 Ne009194770294122b71d3e40261dbb2b
9 anzsrc-for:11
10 anzsrc-for:1112
11 schema:author N9cf580acebd34b4b86452b723f5ce854
12 schema:citation sg:pub.10.1007/978-3-642-59871-5
13 sg:pub.10.1038/300149a0
14 sg:pub.10.1038/labinvest.3780315
15 sg:pub.10.1038/ng1061
16 sg:pub.10.1038/sj.onc.1201044
17 sg:pub.10.1038/sj.onc.1202385
18 sg:pub.10.1038/sj.onc.1204612
19 https://app.dimensions.ai/details/publication/pub.1007403503
20 https://app.dimensions.ai/details/publication/pub.1074880622
21 https://app.dimensions.ai/details/publication/pub.1074993564
22 https://app.dimensions.ai/details/publication/pub.1075019600
23 https://app.dimensions.ai/details/publication/pub.1075198249
24 https://app.dimensions.ai/details/publication/pub.1075214729
25 https://app.dimensions.ai/details/publication/pub.1083119795
26 https://app.dimensions.ai/details/publication/pub.1083232606
27 https://app.dimensions.ai/details/publication/pub.1083251764
28 https://app.dimensions.ai/details/publication/pub.1083360550
29 https://doi.org/10.1001/jama.1974.03230160009002
30 https://doi.org/10.1001/jama.227.3.281
31 https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n
32 https://doi.org/10.1002/cncr.11778
33 https://doi.org/10.1002/cncr.20095
34 https://doi.org/10.1002/ijc.20204
35 https://doi.org/10.1002/jcb.240501314
36 https://doi.org/10.1016/0046-8177(92)90285-b
37 https://doi.org/10.1016/0090-4295(77)90227-8
38 https://doi.org/10.1016/s0022-5347(05)63991-2
39 https://doi.org/10.1016/s0090-4295(01)00968-2
40 https://doi.org/10.1056/nejm199101103240211
41 https://doi.org/10.1089/106652701753307539
42 https://doi.org/10.1093/jnci/93.6.413
43 https://doi.org/10.1093/jnci/94.17.1320
44 https://doi.org/10.1097/00005392-199902000-00106
45 https://doi.org/10.1111/j.1750-3639.2002.tb00426.x
46 https://doi.org/10.1158/0008-5472.can-03-3620
47 https://doi.org/10.1177/29.4.6166661
48 https://doi.org/10.1200/jco.2004.03.118
49 https://doi.org/10.1200/jco.2004.12.994
50 https://doi.org/10.2144/01311st01
51 https://doi.org/10.3322/canjclin.54.1.8
52 schema:datePublished 2005-04
53 schema:datePublishedReg 2005-04-01
54 schema:description Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from preneoplasia along papillary and nonpapillary pathways. The expression profiles of 19 pairs of RNA samples from adjacent urothelium and tumors were analyzed using cDNA microarrays. For selected genes their expressions were verified on a cohort of 251 bladder cancer patients using tissue microarray and immunohistochemistry and were related to clinicopathological parameters including follow-up data. We identified alterations in seven gene clusters controlling proliferation, differentiation, and programmed cell death that were common for papillary and nonpapillary cancer. In contrast, genes controlling cellular and stromal interactions were altered in the nonpapillary cancer. The expression levels of only two genes from this group could be used to define an aggressive form of the disease. Tumors characterized by the low expression of e-cadherin and the high expression of DNA alpha-topoisomerase II had a high propensity for distant metastasis and were associated with poor survival.
55 schema:genre research_article
56 schema:inLanguage en
57 schema:isAccessibleForFree true
58 schema:isPartOf N3abdb131a4a44faba5e08a2a2e857640
59 Nb27dbab2f1d34c92a918f0bab77a223c
60 sg:journal.1017964
61 schema:name Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways
62 schema:pagination 532
63 schema:productId N5838270422be46a3b08964e9bd07dace
64 N95c158ee4b4c4867b47ada01568c2c15
65 N99a701a719374450bd018b1b8e223aa2
66 Na385d66535614ba38b25bdcdd45f33aa
67 Naadbd7e8150c4031bc0c1da070d31d66
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017472931
69 https://doi.org/10.1038/labinvest.3700250
70 schema:sdDatePublished 2019-04-11T13:17
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher N9893a69e5bd841caab5b7bda20b586cd
73 schema:url https://www.nature.com/articles/3700250
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N060abc64dc25477c9c4e9f1cf82fcc94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Multigene Family
79 rdf:type schema:DefinedTerm
80 N18e7fd8e6e6a4617a991633f2b98d2b1 rdf:first sg:person.016205341247.35
81 rdf:rest Ne8bfefebcba54ff98145f6100c69f0b0
82 N1a86feff789342cab94691d4e3047dc7 rdf:first sg:person.013732343337.08
83 rdf:rest N748ba19bc9744dbb907b5488778c9f84
84 N1e9c7290292a40e2a8d92535ff61d608 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Reverse Transcriptase Polymerase Chain Reaction
86 rdf:type schema:DefinedTerm
87 N2a5600f9c37c47cca80bf681a6bc6f4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name DNA, Complementary
89 rdf:type schema:DefinedTerm
90 N3abdb131a4a44faba5e08a2a2e857640 schema:volumeNumber 85
91 rdf:type schema:PublicationVolume
92 N3d9dee14539f4803a73365f1f2e93b6a rdf:first Ned50977661ad4501a04913e0aab2b86e
93 rdf:rest N1a86feff789342cab94691d4e3047dc7
94 N45c1b306a96346d0b19380fa9bf0c598 rdf:first sg:person.0731747000.61
95 rdf:rest N872357a421ec4a3f9b4dc06a3be9bfc7
96 N5794d802eeea4cd0899878b3fac20834 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
97 schema:familyName Kim
98 schema:givenName Jai-Hyun
99 rdf:type schema:Person
100 N5838270422be46a3b08964e9bd07dace schema:name nlm_unique_id
101 schema:value 0376617
102 rdf:type schema:PropertyValue
103 N5d460019224f41258317282877abb18a rdf:first sg:person.01020612040.52
104 rdf:rest N45c1b306a96346d0b19380fa9bf0c598
105 N5d949bf9e444466ab614acd60bc58146 rdf:first sg:person.0635271651.60
106 rdf:rest rdf:nil
107 N616ca1565fe5481baf5baa681dadf029 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Immunohistochemistry
109 rdf:type schema:DefinedTerm
110 N748ba19bc9744dbb907b5488778c9f84 rdf:first sg:person.012610632077.22
111 rdf:rest N5d460019224f41258317282877abb18a
112 N872357a421ec4a3f9b4dc06a3be9bfc7 rdf:first sg:person.012724545020.23
113 rdf:rest N5d949bf9e444466ab614acd60bc58146
114 N95c158ee4b4c4867b47ada01568c2c15 schema:name dimensions_id
115 schema:value pub.1017472931
116 rdf:type schema:PropertyValue
117 N9893a69e5bd841caab5b7bda20b586cd schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 N99a701a719374450bd018b1b8e223aa2 schema:name pubmed_id
120 schema:value 15778693
121 rdf:type schema:PropertyValue
122 N9cf580acebd34b4b86452b723f5ce854 rdf:first N5794d802eeea4cd0899878b3fac20834
123 rdf:rest Nfe6bb5950f4d421eaa59c6c49a705461
124 Na385d66535614ba38b25bdcdd45f33aa schema:name doi
125 schema:value 10.1038/labinvest.3700250
126 rdf:type schema:PropertyValue
127 Na66ecf653da1461fbcf2680ea413f5e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Urinary Bladder Neoplasms
129 rdf:type schema:DefinedTerm
130 Naadbd7e8150c4031bc0c1da070d31d66 schema:name readcube_id
131 schema:value 533f6050ec65b2bc51369053f64ac8b199dfbcce8d739288e188137aa58d8bae
132 rdf:type schema:PropertyValue
133 Nb14b10122a3b4bda98bc316cc6fc3d04 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Humans
135 rdf:type schema:DefinedTerm
136 Nb27dbab2f1d34c92a918f0bab77a223c schema:issueNumber 4
137 rdf:type schema:PublicationIssue
138 Ncfba8d23800a4247a64e6fc88b67631d rdf:first sg:person.0737211130.77
139 rdf:rest N3d9dee14539f4803a73365f1f2e93b6a
140 Nd3f6b764d8dc4182a5ba39eff15f6af7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Transcription, Genetic
142 rdf:type schema:DefinedTerm
143 Ne009194770294122b71d3e40261dbb2b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Oligonucleotide Array Sequence Analysis
145 rdf:type schema:DefinedTerm
146 Ne8bfefebcba54ff98145f6100c69f0b0 rdf:first sg:person.0702713543.67
147 rdf:rest Ncfba8d23800a4247a64e6fc88b67631d
148 Ned50977661ad4501a04913e0aab2b86e schema:affiliation https://www.grid.ac/institutes/grid.240145.6
149 schema:familyName Kim
150 schema:givenName MiSook
151 rdf:type schema:Person
152 Nfe6bb5950f4d421eaa59c6c49a705461 rdf:first sg:person.01175340240.51
153 rdf:rest N18e7fd8e6e6a4617a991633f2b98d2b1
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
158 schema:name Oncology and Carcinogenesis
159 rdf:type schema:DefinedTerm
160 sg:grant.2440171 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
161 rdf:type schema:MonetaryGrant
162 sg:grant.2472268 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
163 rdf:type schema:MonetaryGrant
164 sg:grant.2626451 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
165 rdf:type schema:MonetaryGrant
166 sg:grant.2688897 http://pending.schema.org/fundedItem sg:pub.10.1038/labinvest.3700250
167 rdf:type schema:MonetaryGrant
168 sg:journal.1017964 schema:issn 0023-6837
169 1530-0307
170 schema:name Laboratory Investigation
171 rdf:type schema:Periodical
172 sg:person.01020612040.52 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
173 schema:familyName Grossman
174 schema:givenName Herbert Barton
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020612040.52
176 rdf:type schema:Person
177 sg:person.01175340240.51 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
178 schema:familyName Tuziak
179 schema:givenName Tomasz
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175340240.51
181 rdf:type schema:Person
182 sg:person.012610632077.22 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
183 schema:familyName Dinney
184 schema:givenName Colin
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012610632077.22
186 rdf:type schema:Person
187 sg:person.012724545020.23 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
188 schema:familyName Zhang
189 schema:givenName Wei
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012724545020.23
191 rdf:type schema:Person
192 sg:person.013732343337.08 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
193 schema:familyName Fuller
194 schema:givenName Gregory
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732343337.08
196 rdf:type schema:Person
197 sg:person.016205341247.35 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
198 schema:familyName Hu
199 schema:givenName Limei
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016205341247.35
201 rdf:type schema:Person
202 sg:person.0635271651.60 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
203 schema:familyName Czerniak
204 schema:givenName Bogdan
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635271651.60
206 rdf:type schema:Person
207 sg:person.0702713543.67 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
208 schema:familyName Wang
209 schema:givenName Zhi
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702713543.67
211 rdf:type schema:Person
212 sg:person.0731747000.61 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
213 schema:familyName Baggerly
214 schema:givenName Keith
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731747000.61
216 rdf:type schema:Person
217 sg:person.0737211130.77 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
218 schema:familyName Bondaruk
219 schema:givenName Jolanta
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737211130.77
221 rdf:type schema:Person
222 sg:pub.10.1007/978-3-642-59871-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007403503
223 https://doi.org/10.1007/978-3-642-59871-5
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/300149a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038315851
226 https://doi.org/10.1038/300149a0
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/labinvest.3780315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041334550
229 https://doi.org/10.1038/labinvest.3780315
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/ng1061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044852770
232 https://doi.org/10.1038/ng1061
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/sj.onc.1201044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001246428
235 https://doi.org/10.1038/sj.onc.1201044
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/sj.onc.1202385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024660747
238 https://doi.org/10.1038/sj.onc.1202385
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/sj.onc.1204612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000444160
241 https://doi.org/10.1038/sj.onc.1204612
242 rdf:type schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1007403503 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1074880622 schema:CreativeWork
245 https://app.dimensions.ai/details/publication/pub.1074993564 schema:CreativeWork
246 https://app.dimensions.ai/details/publication/pub.1075019600 schema:CreativeWork
247 https://app.dimensions.ai/details/publication/pub.1075198249 schema:CreativeWork
248 https://app.dimensions.ai/details/publication/pub.1075214729 schema:CreativeWork
249 https://app.dimensions.ai/details/publication/pub.1083119795 schema:CreativeWork
250 https://app.dimensions.ai/details/publication/pub.1083232606 schema:CreativeWork
251 https://app.dimensions.ai/details/publication/pub.1083251764 schema:CreativeWork
252 https://app.dimensions.ai/details/publication/pub.1083360550 schema:CreativeWork
253 https://doi.org/10.1001/jama.1974.03230160009002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045610845
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1001/jama.227.3.281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054130555
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1002/(sici)1098-2264(200004)27:4<392::aid-gcc9>3.0.co;2-n schema:sameAs https://app.dimensions.ai/details/publication/pub.1018653167
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1002/cncr.11778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044745311
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1002/cncr.20095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041460872
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1002/ijc.20204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025558586
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1002/jcb.240501314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010918080
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/0046-8177(92)90285-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1011295893
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/0090-4295(77)90227-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016061438
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0022-5347(05)63991-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021735475
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/s0090-4295(01)00968-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051113271
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1056/nejm199101103240211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043838552
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1089/106652701753307539 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059204913
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1093/jnci/93.6.413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011728937
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1093/jnci/94.17.1320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009989679
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1097/00005392-199902000-00106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060216290
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1111/j.1750-3639.2002.tb00426.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006415372
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1158/0008-5472.can-03-3620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005461901
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1177/29.4.6166661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029463505
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1200/jco.2004.03.118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006309480
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1200/jco.2004.12.994 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016348735
294 rdf:type schema:CreativeWork
295 https://doi.org/10.2144/01311st01 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074852712
296 rdf:type schema:CreativeWork
297 https://doi.org/10.3322/canjclin.54.1.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001408630
298 rdf:type schema:CreativeWork
299 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
300 schema:name Department of Biostatistics and Applied Mathematics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
301 Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
302 Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
303 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...