Effect of indomethacin on glomerular permselectivity and hemodynamics in nephrotoxic serum nephritis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1989-07

AUTHORS

Joel Neugarten, Arthur Kozin, Karen Cook

ABSTRACT

The present study was undertaken to determine the effects of prostaglandin synthesis inhibition on glomerular hemodynamics in nephrotoxic serum nephritis and to elucidate the mechanisms by which prostaglandin synthesis inhibition reduces proteinuria in nephritic rats. Dextran sieving studies were performed before and after intravenous administration of indomethacin to control rats and to nephritic rats with heavy proteinuria. Indomethacin did not significantly alter mean arterial pressure, glomerular filtration rate or proteinuria in control rats nor were significant changes in dextran sieving observed. By contrast, in nephritic rats indomethacin significantly reduced glomerular filtration rate (2.58 +/- 0.50 vs. 1.39 +/- 0.27 ml/min, P less than 0.001), proteinuria (0.198 +/- 0.079 vs. 0.048 +/- 0.019 mg/min, P less than 0.05) and filtration rate-corrected proteinuria (0.059 +/- 0.033 vs. 0.031 +/- 0.013 mg/ml GFR, P less than 0.05). The fractional clearance of neutral dextrans with molecular radii exceeding 42 A were elevated above control values in nephritic rats (P less than 0.05). After administration of indomethacin, the fractional clearance of neutral dextrans uniformly declined toward control values and remained elevated only for molecular radii exceeding 54 A. Assessment of glomerular hemodynamics in nephritic rats before and after indomethacin showed significant declines in single nephron filtration rate (31.5 +/- 3.0 vs. 21.2 +/- 2.5 nl/min, P less than 0.02), glomerular plasma flow rate (99.5 +/- 6.7 vs. 68.5 +/- 7.8 nl/min, P less than 0.05) and glomerular ultrafiltration coefficient (0.0430 +/- 0.0033 vs. 0.0339 +/- 0.0032 nl.sec-1.mm Hg-1, p less than 0.05). Indomethacin did not significantly change these parameters in control rats.(ABSTRACT TRUNCATED AT 250 WORDS) More... »

PAGES

51-56

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ki.1989.160

DOI

http://dx.doi.org/10.1038/ki.1989.160

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051588526

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2478751


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Basement Membrane", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dextrans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hemodynamics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indomethacin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Function Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Glomerulus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nephritis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Permeability", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prostaglandins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Inbred Strains", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Montefiore Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240283.f", 
          "name": [
            "Department of Medicine, Renal and Hypertension Division, Montefiore Medical Center, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Neugarten", 
        "givenName": "Joel", 
        "id": "sg:person.01220213202.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220213202.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Albert Einstein College of Medicine", 
          "id": "https://www.grid.ac/institutes/grid.251993.5", 
          "name": [
            "Albert Einstein College of Medicine, Bronx, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kozin", 
        "givenName": "Arthur", 
        "id": "sg:person.01206371752.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206371752.34"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Cook", 
        "givenName": "Karen", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ki.1988.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010277632", 
          "https://doi.org/10.1038/ki.1988.8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0021-9673(01)85930-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013021391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0954-6820.1976.tb06701.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013143650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0954-6820.1976.tb06701.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013143650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1985.132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014992821", 
          "https://doi.org/10.1038/ki.1985.132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000166941", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018483013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci108396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019404212"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1982.163", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022459808", 
          "https://doi.org/10.1038/ki.1982.163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-2697(76)90527-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025529346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1987.147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031089315", 
          "https://doi.org/10.1038/ki.1987.147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000181478", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038403784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci107934", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041075524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci112384", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043411199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1982.23", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046451379", 
          "https://doi.org/10.1038/ki.1982.23"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1983.199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049631355", 
          "https://doi.org/10.1038/ki.1983.199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1979.133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051816411", 
          "https://doi.org/10.1038/ki.1979.133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-6980(85)90192-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052816317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(86)90910-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053014856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079796345", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajprenal.1987.252.5.f829", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079832293"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajprenal.1985.248.2.f240", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080034381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajprenal.1985.249.3.f374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080094712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080277998", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplegacy.1972.223.5.1178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080504803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplegacy.1971.220.1.148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081156046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081726561", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1989-07", 
    "datePublishedReg": "1989-07-01", 
    "description": "The present study was undertaken to determine the effects of prostaglandin synthesis inhibition on glomerular hemodynamics in nephrotoxic serum nephritis and to elucidate the mechanisms by which prostaglandin synthesis inhibition reduces proteinuria in nephritic rats. Dextran sieving studies were performed before and after intravenous administration of indomethacin to control rats and to nephritic rats with heavy proteinuria. Indomethacin did not significantly alter mean arterial pressure, glomerular filtration rate or proteinuria in control rats nor were significant changes in dextran sieving observed. By contrast, in nephritic rats indomethacin significantly reduced glomerular filtration rate (2.58 +/- 0.50 vs. 1.39 +/- 0.27 ml/min, P less than 0.001), proteinuria (0.198 +/- 0.079 vs. 0.048 +/- 0.019 mg/min, P less than 0.05) and filtration rate-corrected proteinuria (0.059 +/- 0.033 vs. 0.031 +/- 0.013 mg/ml GFR, P less than 0.05). The fractional clearance of neutral dextrans with molecular radii exceeding 42 A were elevated above control values in nephritic rats (P less than 0.05). After administration of indomethacin, the fractional clearance of neutral dextrans uniformly declined toward control values and remained elevated only for molecular radii exceeding 54 A. Assessment of glomerular hemodynamics in nephritic rats before and after indomethacin showed significant declines in single nephron filtration rate (31.5 +/- 3.0 vs. 21.2 +/- 2.5 nl/min, P less than 0.02), glomerular plasma flow rate (99.5 +/- 6.7 vs. 68.5 +/- 7.8 nl/min, P less than 0.05) and glomerular ultrafiltration coefficient (0.0430 +/- 0.0033 vs. 0.0339 +/- 0.0032 nl.sec-1.mm Hg-1, p less than 0.05). Indomethacin did not significantly change these parameters in control rats.(ABSTRACT TRUNCATED AT 250 WORDS)", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ki.1989.160", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1015319", 
        "issn": [
          "0085-2538", 
          "1523-1755"
        ], 
        "name": "Kidney International", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "36"
      }
    ], 
    "name": "Effect of indomethacin on glomerular permselectivity and hemodynamics in nephrotoxic serum nephritis", 
    "pagination": "51-56", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f5be275eb83d858c818b3c41b206a98220d957cf340578bb3f77eff8ffea65bb"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "2478751"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0323470"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ki.1989.160"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1051588526"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ki.1989.160", 
      "https://app.dimensions.ai/details/publication/pub.1051588526"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000426.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ki/journal/v36/n1/abs/ki1989160a.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ki.1989.160'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ki.1989.160'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ki.1989.160'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ki.1989.160'


 

This table displays all metadata directly associated to this object as RDF triples.

215 TRIPLES      21 PREDICATES      67 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ki.1989.160 schema:about N03997d9cf8f54042af9d24a45fce83f1
2 N2005b040f4d247f7a658b3ac1074baa5
3 N2fc0760fa76b485fa0128fb81c36c361
4 N3aa8b006d5a34830a54b9fbf013c074e
5 N3beb7b3483264bb48abf781583aa3900
6 N41faf67698364fd38bb942355e542490
7 N45ebd4248eae4ad996d12e5fd3a59023
8 N710de8824f324739b215988786797e6e
9 N8d86df3ac90748b7835a322790fa104a
10 Naf0d7c4cd2b248b8ae12874e5ac556dc
11 Ndd83488f2af84f50b8dfd27f26531934
12 Nf71f87e232314ca1b1e659b85cc6d9f8
13 Nf7e3fe27feb04996b0f97c607e4b61c7
14 anzsrc-for:11
15 anzsrc-for:1109
16 schema:author N4b0866566b8d4baf98df1ca26c8a281d
17 schema:citation sg:pub.10.1038/ki.1979.133
18 sg:pub.10.1038/ki.1982.163
19 sg:pub.10.1038/ki.1982.23
20 sg:pub.10.1038/ki.1983.199
21 sg:pub.10.1038/ki.1985.132
22 sg:pub.10.1038/ki.1987.147
23 sg:pub.10.1038/ki.1988.8
24 https://app.dimensions.ai/details/publication/pub.1079796345
25 https://app.dimensions.ai/details/publication/pub.1080277998
26 https://app.dimensions.ai/details/publication/pub.1081726561
27 https://doi.org/10.1016/0002-9343(86)90910-1
28 https://doi.org/10.1016/0003-2697(76)90527-3
29 https://doi.org/10.1016/0090-6980(85)90192-3
30 https://doi.org/10.1016/s0021-9673(01)85930-6
31 https://doi.org/10.1111/j.0954-6820.1976.tb06701.x
32 https://doi.org/10.1152/ajplegacy.1971.220.1.148
33 https://doi.org/10.1152/ajplegacy.1972.223.5.1178
34 https://doi.org/10.1152/ajprenal.1985.248.2.f240
35 https://doi.org/10.1152/ajprenal.1985.249.3.f374
36 https://doi.org/10.1152/ajprenal.1987.252.5.f829
37 https://doi.org/10.1159/000166941
38 https://doi.org/10.1159/000181478
39 https://doi.org/10.1172/jci107934
40 https://doi.org/10.1172/jci108396
41 https://doi.org/10.1172/jci112384
42 schema:datePublished 1989-07
43 schema:datePublishedReg 1989-07-01
44 schema:description The present study was undertaken to determine the effects of prostaglandin synthesis inhibition on glomerular hemodynamics in nephrotoxic serum nephritis and to elucidate the mechanisms by which prostaglandin synthesis inhibition reduces proteinuria in nephritic rats. Dextran sieving studies were performed before and after intravenous administration of indomethacin to control rats and to nephritic rats with heavy proteinuria. Indomethacin did not significantly alter mean arterial pressure, glomerular filtration rate or proteinuria in control rats nor were significant changes in dextran sieving observed. By contrast, in nephritic rats indomethacin significantly reduced glomerular filtration rate (2.58 +/- 0.50 vs. 1.39 +/- 0.27 ml/min, P less than 0.001), proteinuria (0.198 +/- 0.079 vs. 0.048 +/- 0.019 mg/min, P less than 0.05) and filtration rate-corrected proteinuria (0.059 +/- 0.033 vs. 0.031 +/- 0.013 mg/ml GFR, P less than 0.05). The fractional clearance of neutral dextrans with molecular radii exceeding 42 A were elevated above control values in nephritic rats (P less than 0.05). After administration of indomethacin, the fractional clearance of neutral dextrans uniformly declined toward control values and remained elevated only for molecular radii exceeding 54 A. Assessment of glomerular hemodynamics in nephritic rats before and after indomethacin showed significant declines in single nephron filtration rate (31.5 +/- 3.0 vs. 21.2 +/- 2.5 nl/min, P less than 0.02), glomerular plasma flow rate (99.5 +/- 6.7 vs. 68.5 +/- 7.8 nl/min, P less than 0.05) and glomerular ultrafiltration coefficient (0.0430 +/- 0.0033 vs. 0.0339 +/- 0.0032 nl.sec-1.mm Hg-1, p less than 0.05). Indomethacin did not significantly change these parameters in control rats.(ABSTRACT TRUNCATED AT 250 WORDS)
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree true
48 schema:isPartOf N5577f41545674486b043086991ecf176
49 Na0935449d915451286edf615c5ab49e6
50 sg:journal.1015319
51 schema:name Effect of indomethacin on glomerular permselectivity and hemodynamics in nephrotoxic serum nephritis
52 schema:pagination 51-56
53 schema:productId N6a6bb5a0f88c4ff4bea3cd3b7cb4880f
54 Nc98abb1d876a4a31ac1c68de650e05da
55 Nd99f28f6a7484b1fa650f426ff8ba97b
56 Ndc4f0a6b7030449abad12af6e0ead863
57 Ne98002cb5b4b471783f869c5bcb00da8
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051588526
59 https://doi.org/10.1038/ki.1989.160
60 schema:sdDatePublished 2019-04-10T16:29
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher N843bfa1e8fe4402294b4be8a6f969cf5
63 schema:url http://www.nature.com/ki/journal/v36/n1/abs/ki1989160a.html
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N03997d9cf8f54042af9d24a45fce83f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Rats
69 rdf:type schema:DefinedTerm
70 N2005b040f4d247f7a658b3ac1074baa5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Hemodynamics
72 rdf:type schema:DefinedTerm
73 N2fc0760fa76b485fa0128fb81c36c361 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Dextrans
75 rdf:type schema:DefinedTerm
76 N3aa8b006d5a34830a54b9fbf013c074e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Rats, Inbred Strains
78 rdf:type schema:DefinedTerm
79 N3beb7b3483264bb48abf781583aa3900 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Nephritis
81 rdf:type schema:DefinedTerm
82 N41faf67698364fd38bb942355e542490 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Kidney Function Tests
84 rdf:type schema:DefinedTerm
85 N45ebd4248eae4ad996d12e5fd3a59023 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Indomethacin
87 rdf:type schema:DefinedTerm
88 N4b0866566b8d4baf98df1ca26c8a281d rdf:first sg:person.01220213202.20
89 rdf:rest N5fbcfc2f9f334749919a01f9d8f28e05
90 N5577f41545674486b043086991ecf176 schema:issueNumber 1
91 rdf:type schema:PublicationIssue
92 N5fbcfc2f9f334749919a01f9d8f28e05 rdf:first sg:person.01206371752.34
93 rdf:rest Nd24f68c85dad48da8da795ddc6d49d8a
94 N6a6bb5a0f88c4ff4bea3cd3b7cb4880f schema:name nlm_unique_id
95 schema:value 0323470
96 rdf:type schema:PropertyValue
97 N6ea947a3d3d14b4a886f92605d28057f schema:familyName Cook
98 schema:givenName Karen
99 rdf:type schema:Person
100 N710de8824f324739b215988786797e6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Basement Membrane
102 rdf:type schema:DefinedTerm
103 N843bfa1e8fe4402294b4be8a6f969cf5 schema:name Springer Nature - SN SciGraph project
104 rdf:type schema:Organization
105 N8d86df3ac90748b7835a322790fa104a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Animals
107 rdf:type schema:DefinedTerm
108 Na0935449d915451286edf615c5ab49e6 schema:volumeNumber 36
109 rdf:type schema:PublicationVolume
110 Naf0d7c4cd2b248b8ae12874e5ac556dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Male
112 rdf:type schema:DefinedTerm
113 Nc98abb1d876a4a31ac1c68de650e05da schema:name readcube_id
114 schema:value f5be275eb83d858c818b3c41b206a98220d957cf340578bb3f77eff8ffea65bb
115 rdf:type schema:PropertyValue
116 Nd24f68c85dad48da8da795ddc6d49d8a rdf:first N6ea947a3d3d14b4a886f92605d28057f
117 rdf:rest rdf:nil
118 Nd99f28f6a7484b1fa650f426ff8ba97b schema:name dimensions_id
119 schema:value pub.1051588526
120 rdf:type schema:PropertyValue
121 Ndc4f0a6b7030449abad12af6e0ead863 schema:name pubmed_id
122 schema:value 2478751
123 rdf:type schema:PropertyValue
124 Ndd83488f2af84f50b8dfd27f26531934 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Kidney Glomerulus
126 rdf:type schema:DefinedTerm
127 Ne98002cb5b4b471783f869c5bcb00da8 schema:name doi
128 schema:value 10.1038/ki.1989.160
129 rdf:type schema:PropertyValue
130 Nf71f87e232314ca1b1e659b85cc6d9f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Prostaglandins
132 rdf:type schema:DefinedTerm
133 Nf7e3fe27feb04996b0f97c607e4b61c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Permeability
135 rdf:type schema:DefinedTerm
136 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
137 schema:name Medical and Health Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
140 schema:name Neurosciences
141 rdf:type schema:DefinedTerm
142 sg:journal.1015319 schema:issn 0085-2538
143 1523-1755
144 schema:name Kidney International
145 rdf:type schema:Periodical
146 sg:person.01206371752.34 schema:affiliation https://www.grid.ac/institutes/grid.251993.5
147 schema:familyName Kozin
148 schema:givenName Arthur
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206371752.34
150 rdf:type schema:Person
151 sg:person.01220213202.20 schema:affiliation https://www.grid.ac/institutes/grid.240283.f
152 schema:familyName Neugarten
153 schema:givenName Joel
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220213202.20
155 rdf:type schema:Person
156 sg:pub.10.1038/ki.1979.133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051816411
157 https://doi.org/10.1038/ki.1979.133
158 rdf:type schema:CreativeWork
159 sg:pub.10.1038/ki.1982.163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022459808
160 https://doi.org/10.1038/ki.1982.163
161 rdf:type schema:CreativeWork
162 sg:pub.10.1038/ki.1982.23 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046451379
163 https://doi.org/10.1038/ki.1982.23
164 rdf:type schema:CreativeWork
165 sg:pub.10.1038/ki.1983.199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049631355
166 https://doi.org/10.1038/ki.1983.199
167 rdf:type schema:CreativeWork
168 sg:pub.10.1038/ki.1985.132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014992821
169 https://doi.org/10.1038/ki.1985.132
170 rdf:type schema:CreativeWork
171 sg:pub.10.1038/ki.1987.147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031089315
172 https://doi.org/10.1038/ki.1987.147
173 rdf:type schema:CreativeWork
174 sg:pub.10.1038/ki.1988.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010277632
175 https://doi.org/10.1038/ki.1988.8
176 rdf:type schema:CreativeWork
177 https://app.dimensions.ai/details/publication/pub.1079796345 schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1080277998 schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1081726561 schema:CreativeWork
180 https://doi.org/10.1016/0002-9343(86)90910-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053014856
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/0003-2697(76)90527-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025529346
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/0090-6980(85)90192-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052816317
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/s0021-9673(01)85930-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013021391
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1111/j.0954-6820.1976.tb06701.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013143650
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1152/ajplegacy.1971.220.1.148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081156046
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1152/ajplegacy.1972.223.5.1178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080504803
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1152/ajprenal.1985.248.2.f240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080034381
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1152/ajprenal.1985.249.3.f374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080094712
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1152/ajprenal.1987.252.5.f829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079832293
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1159/000166941 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018483013
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1159/000181478 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038403784
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1172/jci107934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041075524
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1172/jci108396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019404212
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1172/jci112384 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043411199
209 rdf:type schema:CreativeWork
210 https://www.grid.ac/institutes/grid.240283.f schema:alternateName Montefiore Medical Center
211 schema:name Department of Medicine, Renal and Hypertension Division, Montefiore Medical Center, New York, USA
212 rdf:type schema:Organization
213 https://www.grid.ac/institutes/grid.251993.5 schema:alternateName Albert Einstein College of Medicine
214 schema:name Albert Einstein College of Medicine, Bronx, New York, USA
215 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...