Nephrotoxic serum nephritis with hypertension: Amelioration by antihypertensive therapy View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1985-08

AUTHORS

Joel Neugarten, Bernard Kaminetsky, Helen Feiner, Robert G. Schacht, David T. Liu, David S. Baldwin

ABSTRACT

We have examined the effects of antihypertensive therapy on glomerular dynamics and on the clinical and morphologic features of a model of nephrotoxic serum nephritis (NSN) in which hypertension occurs. NSN was induced in uninephrectomized male Sprague Dawley rats, which drank 0.9% sodium chloride ad libitum. One-half were assigned randomly to a treated group whose blood pressure was normalized on a regimen of reserpine, hydralazine, and hydrochlorothiazide. Hypertension continued throughout the 6 weeks of study in untreated rats (blood pressure 148 +/- 5 vs. 103 +/- 3 mm Hg in treated rats, P less than 0.01). Urinary protein excretion was greater (437 +/- 110 vs. 254 +/- 81 mg/24 hr, P less than 0.005), and serum albumin lower (1.6 +/- 0.4 vs. 2.9 +/- 0.3 g/dl, P less than 0.01) in hypertensive animals. Diffuse glomerular endo- and extracapillary proliferation and arteriolar medial hypertrophy were observed frequently in nephritic rats with untreated hypertension. By contrast, structural abnormalities were limited primarily to focal segmental proliferation involving fewer than one-third of glomeruli in the absence of vascular changes in treated normotensive rats. Micropuncture studies performed 8 to 16 days after induction of nephritis showed a reduction in glomerular capillary pressure (46 +/- 1 vs. 55 +/- 1 mm Hg, P less than 0.001), glomerular plasma flow rate (115 +/- 20 vs. 160 +/- 20 nl/min, P less than 0.01), and single nephron filtration rate (42 +/- 4 vs. 56 +/- 5 nl/min, P less than 0.001) with antihypertensive treatment, suggesting that a hemodynamic mechanism may have been responsible for enhanced glomerular injury in the hypertensive nephritic animals. More... »

PAGES

135-139

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ki.1985.132

DOI

http://dx.doi.org/10.1038/ki.1985.132

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014992821

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3834224


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antihypertensive Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dietary Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glomerular Filtration Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydralazine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrochlorothiazide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension, Renal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Glomerulus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nephritis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Inbred Strains", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Circulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reserpine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Neugarten", 
        "givenName": "Joel", 
        "id": "sg:person.01220213202.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220213202.20"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kaminetsky", 
        "givenName": "Bernard", 
        "type": "Person"
      }, 
      {
        "familyName": "Feiner", 
        "givenName": "Helen", 
        "id": "sg:person.0775033253.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775033253.52"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Schacht", 
        "givenName": "Robert G.", 
        "id": "sg:person.01025603601.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025603601.83"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Liu", 
        "givenName": "David T.", 
        "type": "Person"
      }, 
      {
        "familyName": "Baldwin", 
        "givenName": "David S.", 
        "id": "sg:person.01243277047.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243277047.34"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0002-9343(83)90873-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002484645"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1982.17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002978414", 
          "https://doi.org/10.1038/ki.1982.17"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.70.6.615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007997791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1982.163", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022459808", 
          "https://doi.org/10.1038/ki.1982.163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1983.143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023906878", 
          "https://doi.org/10.1038/ki.1983.143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1983.162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033261661", 
          "https://doi.org/10.1038/ki.1983.162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198209093071104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040743632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci107934", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041075524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(77)90344-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048124882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1977.76", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048455888", 
          "https://doi.org/10.1038/ki.1977.76"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1983.199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049631355", 
          "https://doi.org/10.1038/ki.1983.199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1984.66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053297298", 
          "https://doi.org/10.1038/ki.1984.66"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplegacy.1974.227.5.1045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080347386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081610618", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081625515", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082172521", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajprenal.1981.241.1.f85", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082239567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083278678", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1985-08", 
    "datePublishedReg": "1985-08-01", 
    "description": "We have examined the effects of antihypertensive therapy on glomerular dynamics and on the clinical and morphologic features of a model of nephrotoxic serum nephritis (NSN) in which hypertension occurs. NSN was induced in uninephrectomized male Sprague Dawley rats, which drank 0.9% sodium chloride ad libitum. One-half were assigned randomly to a treated group whose blood pressure was normalized on a regimen of reserpine, hydralazine, and hydrochlorothiazide. Hypertension continued throughout the 6 weeks of study in untreated rats (blood pressure 148 +/- 5 vs. 103 +/- 3 mm Hg in treated rats, P less than 0.01). Urinary protein excretion was greater (437 +/- 110 vs. 254 +/- 81 mg/24 hr, P less than 0.005), and serum albumin lower (1.6 +/- 0.4 vs. 2.9 +/- 0.3 g/dl, P less than 0.01) in hypertensive animals. Diffuse glomerular endo- and extracapillary proliferation and arteriolar medial hypertrophy were observed frequently in nephritic rats with untreated hypertension. By contrast, structural abnormalities were limited primarily to focal segmental proliferation involving fewer than one-third of glomeruli in the absence of vascular changes in treated normotensive rats. Micropuncture studies performed 8 to 16 days after induction of nephritis showed a reduction in glomerular capillary pressure (46 +/- 1 vs. 55 +/- 1 mm Hg, P less than 0.001), glomerular plasma flow rate (115 +/- 20 vs. 160 +/- 20 nl/min, P less than 0.01), and single nephron filtration rate (42 +/- 4 vs. 56 +/- 5 nl/min, P less than 0.001) with antihypertensive treatment, suggesting that a hemodynamic mechanism may have been responsible for enhanced glomerular injury in the hypertensive nephritic animals.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ki.1985.132", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1015319", 
        "issn": [
          "0085-2538", 
          "1523-1755"
        ], 
        "name": "Kidney International", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "28"
      }
    ], 
    "name": "Nephrotoxic serum nephritis with hypertension: Amelioration by antihypertensive therapy", 
    "pagination": "135-139", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "476e39c201c6a2a314b6615e9d9d9e8e7c7bc53039dede30022a698236e9b6f3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "3834224"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0323470"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ki.1985.132"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1014992821"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ki.1985.132", 
      "https://app.dimensions.ai/details/publication/pub.1014992821"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000422.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ki/journal/v28/n2/abs/ki1985132a.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ki.1985.132'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ki.1985.132'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ki.1985.132'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ki.1985.132'


 

This table displays all metadata directly associated to this object as RDF triples.

210 TRIPLES      21 PREDICATES      62 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ki.1985.132 schema:about N19df98fc7b9948e19cccc6c67c303326
2 N34337d137fd341b5895f2314c60781be
3 N3b7bb335a3a64a8891c613e6cac66755
4 N3bd974bc4dad44e6989ed1a3701b8075
5 N575c4d13cd68472cbd41cf99bfe73865
6 N64e1785629674360898380142af580f9
7 N6cfdf7ea58cc499d8220f03d6ab66034
8 N70967df965644e4d9250a928509ea93b
9 N7688bce9f843498a8d8ade939521885a
10 N81d04e78dc5f43e495dcb10033c7beec
11 N88986475474e450facc52be3e546940e
12 N8a5809e35a254b97854e2e9ee041f6df
13 Nae0066f0800748c39ad336d57835ac23
14 Nbee0357eae0546dbaa41120e44bc317f
15 Ne0d9601d025e42259d7121a7f07b7eda
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nfb7e4cb9912e4733800c6efa84e250d2
19 schema:citation sg:pub.10.1038/ki.1977.76
20 sg:pub.10.1038/ki.1982.163
21 sg:pub.10.1038/ki.1982.17
22 sg:pub.10.1038/ki.1983.143
23 sg:pub.10.1038/ki.1983.162
24 sg:pub.10.1038/ki.1983.199
25 sg:pub.10.1038/ki.1984.66
26 https://app.dimensions.ai/details/publication/pub.1081610618
27 https://app.dimensions.ai/details/publication/pub.1081625515
28 https://app.dimensions.ai/details/publication/pub.1082172521
29 https://app.dimensions.ai/details/publication/pub.1083278678
30 https://doi.org/10.1016/0002-9343(77)90344-8
31 https://doi.org/10.1016/0002-9343(83)90873-2
32 https://doi.org/10.1056/nejm198209093071104
33 https://doi.org/10.1084/jem.70.6.615
34 https://doi.org/10.1152/ajplegacy.1974.227.5.1045
35 https://doi.org/10.1152/ajprenal.1981.241.1.f85
36 https://doi.org/10.1172/jci107934
37 schema:datePublished 1985-08
38 schema:datePublishedReg 1985-08-01
39 schema:description We have examined the effects of antihypertensive therapy on glomerular dynamics and on the clinical and morphologic features of a model of nephrotoxic serum nephritis (NSN) in which hypertension occurs. NSN was induced in uninephrectomized male Sprague Dawley rats, which drank 0.9% sodium chloride ad libitum. One-half were assigned randomly to a treated group whose blood pressure was normalized on a regimen of reserpine, hydralazine, and hydrochlorothiazide. Hypertension continued throughout the 6 weeks of study in untreated rats (blood pressure 148 +/- 5 vs. 103 +/- 3 mm Hg in treated rats, P less than 0.01). Urinary protein excretion was greater (437 +/- 110 vs. 254 +/- 81 mg/24 hr, P less than 0.005), and serum albumin lower (1.6 +/- 0.4 vs. 2.9 +/- 0.3 g/dl, P less than 0.01) in hypertensive animals. Diffuse glomerular endo- and extracapillary proliferation and arteriolar medial hypertrophy were observed frequently in nephritic rats with untreated hypertension. By contrast, structural abnormalities were limited primarily to focal segmental proliferation involving fewer than one-third of glomeruli in the absence of vascular changes in treated normotensive rats. Micropuncture studies performed 8 to 16 days after induction of nephritis showed a reduction in glomerular capillary pressure (46 +/- 1 vs. 55 +/- 1 mm Hg, P less than 0.001), glomerular plasma flow rate (115 +/- 20 vs. 160 +/- 20 nl/min, P less than 0.01), and single nephron filtration rate (42 +/- 4 vs. 56 +/- 5 nl/min, P less than 0.001) with antihypertensive treatment, suggesting that a hemodynamic mechanism may have been responsible for enhanced glomerular injury in the hypertensive nephritic animals.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree true
43 schema:isPartOf N70ca97e388604c6a8be810b7683c36f7
44 Ne757906d37c141ca81da125d7bce64ca
45 sg:journal.1015319
46 schema:name Nephrotoxic serum nephritis with hypertension: Amelioration by antihypertensive therapy
47 schema:pagination 135-139
48 schema:productId N09544afa0f314f98bac26f3f129523bd
49 N6e759a1b86ed4a65a13d55f03b77af19
50 N7dfec331850f4fe0b7aa0cad9cc99d73
51 N7f4c2d98da0f4aad9fa2cf7868086a2d
52 Na4f2a9cd73824479b0c72585425394c3
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014992821
54 https://doi.org/10.1038/ki.1985.132
55 schema:sdDatePublished 2019-04-10T18:08
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher Nec317fc5041d4eacac55b9da2971f58e
58 schema:url http://www.nature.com/ki/journal/v28/n2/abs/ki1985132a.html
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N09544afa0f314f98bac26f3f129523bd schema:name doi
63 schema:value 10.1038/ki.1985.132
64 rdf:type schema:PropertyValue
65 N15c4f670001e4896956805bae2e92c57 schema:familyName Liu
66 schema:givenName David T.
67 rdf:type schema:Person
68 N19df98fc7b9948e19cccc6c67c303326 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Hydrochlorothiazide
70 rdf:type schema:DefinedTerm
71 N22f601770387402f88318b9344700296 rdf:first sg:person.01243277047.34
72 rdf:rest rdf:nil
73 N34337d137fd341b5895f2314c60781be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Kidney Glomerulus
75 rdf:type schema:DefinedTerm
76 N3b7bb335a3a64a8891c613e6cac66755 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Glomerular Filtration Rate
78 rdf:type schema:DefinedTerm
79 N3bd974bc4dad44e6989ed1a3701b8075 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Reserpine
81 rdf:type schema:DefinedTerm
82 N575c4d13cd68472cbd41cf99bfe73865 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Hydralazine
84 rdf:type schema:DefinedTerm
85 N5e6721cb03134b6d9767b6f96cb7d9aa rdf:first sg:person.0775033253.52
86 rdf:rest N8b7ba80286cb44ccb1fd0dd41c551ca4
87 N62095d1f7a594bc0897fb7bcc44d19ac schema:familyName Kaminetsky
88 schema:givenName Bernard
89 rdf:type schema:Person
90 N64e1785629674360898380142af580f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Male
92 rdf:type schema:DefinedTerm
93 N6cfdf7ea58cc499d8220f03d6ab66034 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Rats, Inbred Strains
95 rdf:type schema:DefinedTerm
96 N6e759a1b86ed4a65a13d55f03b77af19 schema:name pubmed_id
97 schema:value 3834224
98 rdf:type schema:PropertyValue
99 N70967df965644e4d9250a928509ea93b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Antihypertensive Agents
101 rdf:type schema:DefinedTerm
102 N70ca97e388604c6a8be810b7683c36f7 schema:issueNumber 2
103 rdf:type schema:PublicationIssue
104 N7688bce9f843498a8d8ade939521885a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Rats
106 rdf:type schema:DefinedTerm
107 N7dfec331850f4fe0b7aa0cad9cc99d73 schema:name readcube_id
108 schema:value 476e39c201c6a2a314b6615e9d9d9e8e7c7bc53039dede30022a698236e9b6f3
109 rdf:type schema:PropertyValue
110 N7f4c2d98da0f4aad9fa2cf7868086a2d schema:name dimensions_id
111 schema:value pub.1014992821
112 rdf:type schema:PropertyValue
113 N81d04e78dc5f43e495dcb10033c7beec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Kidney
115 rdf:type schema:DefinedTerm
116 N88986475474e450facc52be3e546940e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Animals
118 rdf:type schema:DefinedTerm
119 N8a5809e35a254b97854e2e9ee041f6df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Dietary Proteins
121 rdf:type schema:DefinedTerm
122 N8b7ba80286cb44ccb1fd0dd41c551ca4 rdf:first sg:person.01025603601.83
123 rdf:rest Na8b45f37de0241659eb677e6d0d70bda
124 Na4f2a9cd73824479b0c72585425394c3 schema:name nlm_unique_id
125 schema:value 0323470
126 rdf:type schema:PropertyValue
127 Na8b45f37de0241659eb677e6d0d70bda rdf:first N15c4f670001e4896956805bae2e92c57
128 rdf:rest N22f601770387402f88318b9344700296
129 Nac62a7db1e87440386f55a2cb6aa8d08 rdf:first N62095d1f7a594bc0897fb7bcc44d19ac
130 rdf:rest N5e6721cb03134b6d9767b6f96cb7d9aa
131 Nae0066f0800748c39ad336d57835ac23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Nephritis
133 rdf:type schema:DefinedTerm
134 Nbee0357eae0546dbaa41120e44bc317f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Renal Circulation
136 rdf:type schema:DefinedTerm
137 Ne0d9601d025e42259d7121a7f07b7eda schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Hypertension, Renal
139 rdf:type schema:DefinedTerm
140 Ne757906d37c141ca81da125d7bce64ca schema:volumeNumber 28
141 rdf:type schema:PublicationVolume
142 Nec317fc5041d4eacac55b9da2971f58e schema:name Springer Nature - SN SciGraph project
143 rdf:type schema:Organization
144 Nfb7e4cb9912e4733800c6efa84e250d2 rdf:first sg:person.01220213202.20
145 rdf:rest Nac62a7db1e87440386f55a2cb6aa8d08
146 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
147 schema:name Medical and Health Sciences
148 rdf:type schema:DefinedTerm
149 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
150 schema:name Clinical Sciences
151 rdf:type schema:DefinedTerm
152 sg:journal.1015319 schema:issn 0085-2538
153 1523-1755
154 schema:name Kidney International
155 rdf:type schema:Periodical
156 sg:person.01025603601.83 schema:familyName Schacht
157 schema:givenName Robert G.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025603601.83
159 rdf:type schema:Person
160 sg:person.01220213202.20 schema:familyName Neugarten
161 schema:givenName Joel
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220213202.20
163 rdf:type schema:Person
164 sg:person.01243277047.34 schema:familyName Baldwin
165 schema:givenName David S.
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243277047.34
167 rdf:type schema:Person
168 sg:person.0775033253.52 schema:familyName Feiner
169 schema:givenName Helen
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775033253.52
171 rdf:type schema:Person
172 sg:pub.10.1038/ki.1977.76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048455888
173 https://doi.org/10.1038/ki.1977.76
174 rdf:type schema:CreativeWork
175 sg:pub.10.1038/ki.1982.163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022459808
176 https://doi.org/10.1038/ki.1982.163
177 rdf:type schema:CreativeWork
178 sg:pub.10.1038/ki.1982.17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002978414
179 https://doi.org/10.1038/ki.1982.17
180 rdf:type schema:CreativeWork
181 sg:pub.10.1038/ki.1983.143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023906878
182 https://doi.org/10.1038/ki.1983.143
183 rdf:type schema:CreativeWork
184 sg:pub.10.1038/ki.1983.162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033261661
185 https://doi.org/10.1038/ki.1983.162
186 rdf:type schema:CreativeWork
187 sg:pub.10.1038/ki.1983.199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049631355
188 https://doi.org/10.1038/ki.1983.199
189 rdf:type schema:CreativeWork
190 sg:pub.10.1038/ki.1984.66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053297298
191 https://doi.org/10.1038/ki.1984.66
192 rdf:type schema:CreativeWork
193 https://app.dimensions.ai/details/publication/pub.1081610618 schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1081625515 schema:CreativeWork
195 https://app.dimensions.ai/details/publication/pub.1082172521 schema:CreativeWork
196 https://app.dimensions.ai/details/publication/pub.1083278678 schema:CreativeWork
197 https://doi.org/10.1016/0002-9343(77)90344-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048124882
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/0002-9343(83)90873-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002484645
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1056/nejm198209093071104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040743632
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1084/jem.70.6.615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007997791
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1152/ajplegacy.1974.227.5.1045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080347386
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1152/ajprenal.1981.241.1.f85 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082239567
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1172/jci107934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041075524
210 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...