A decision-making tool for exchange transfusions in infants with severe hyperbilirubinemia in resource-limited settings View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-03-03

AUTHORS

B O Olusanya, I F Iskander, T M Slusher, R P Wennberg

ABSTRACT

Late presentation and ineffective phototherapy account for excessive rates of avoidable exchange transfusions (ETs) in many low- and middle-income countries. Several system-based constraints sometimes limit the ability to provide timely ETs for all infants at risk of kernicterus, thus necessitating a treatment triage to optimize available resources. This article proposes a practical priority-setting model for term and near-term infants requiring ET after the first 48 h of life. The proposed model combines plasma/serum bilirubin estimation, clinical signs of acute bilirubin encephalopathy and neurotoxicity risk factors for predicting the risk of kernicterus based on available evidence in the literature. More... »

PAGES

338-341

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/jp.2016.25

DOI

http://dx.doi.org/10.1038/jp.2016.25

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046961298

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26938921


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207 grid-institutes:grid.414021.2 schema:alternateName Department of Pediatrics, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN, USA
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210 grid-institutes:grid.452302.2 schema:alternateName Centre for Healthy Start Initiative, Lagos, Nigeria
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213 grid-institutes:grid.7776.1 schema:alternateName Department of Pediatrics, Cairo University, Cairo, Egypt
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