Neuropsychological and behavioral effects of postnatal dexamethasone in extremely low birth weight preterm children at early school age View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-02

AUTHORS

K C Crotty, M D Ahronovich, I S Baron, R Baker, K Erickson, F R Litman

ABSTRACT

OBJECTIVE: To study postnatal dexamethasone treatment effects on cognitive, neuropsychological and behavioral functioning at early school age in preterm children. STUDY DESIGN: We recruited 222 children born between 1998 and 2003: 114 extremely low birth weight (<1000 g; 60 dexamethasone-treated; 54 untreated) and 108 term-born. Data were analyzed using multivariate methods. RESULT: Preterm performed below term-born on all measures. Dexamethasone-treated performed below dexamethasone-untreated in immediate visual memory, visual-motor integration, mathematical skill and motor dexterity. However, stepwise regression indicated that medical and sociodemographic factors other than dexamethasone contributed to preterm group differences. CONCLUSION: Dexamethasone alone does not explain neurocognitive impairment in preterm children. Medical and sociodemographic factors (illness severity, male gender and parental education) are influential. Prospective longitudinal neuropsychological and behavioral study from preschool to school age that considers medical and sociodemographic variables will best address effects of dexamethasone exposure. More... »

PAGES

jp201162

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/jp.2011.62

DOI

http://dx.doi.org/10.1038/jp.2011.62

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023953229

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21546939


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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/jp.2011.62'


 

This table displays all metadata directly associated to this object as RDF triples.

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