Ontology type: schema:ScholarlyArticle Open Access: True
2008-07
AUTHORSJ Lee, S Ma, D Heng, S K Chew, K Hughes, E S Tai
ABSTRACTThe current hypertension (HTN) guidelines recommend the assessment of other cardiovascular disease (CVD) risk factors in individuals with HTN for further management. Few studies in Asian populations have been published to identify the outcome of individuals with HTN and other CVD risk factors. This study aims to assess the effect of HTN alone, and in combination with other CVD risk factors on all-cause and CVD mortality. Three cross-sectional studies carried out in Singapore (baseline 1982--1995) consisting of 5830 persons were grouped by the absence or presence of HTN and CVD risk factors. They were followed-up (mean 14.1 years) by linkage with the National Death Register. Cox's proportional hazards model was used to obtain adjusted hazard ratios (HRs) for risk of mortality. HTN individuals with either <2 CVD risk factors (adjusted HR 1.4; 95% confidence interval (CI) 1.0-1.8) or > or =2 CVD risk factors (adjusted HR 2.3; 95% CI 1.9-3.0) were at increased risk of all-cause mortality compared to normotensive individuals. The findings were similar for CVD mortality. HTN individuals who also smoked or had diabetes were at highest risk of all-cause mortality, whereas those with elevated total cholesterol/high-density lipoprotein cholesterol, smoked or diabetes had the highest risk for CVD mortality. These findings show that in HTN individuals it is important to assess the presence of other CVD risk factors and manage accordingly. More... »
PAGES468
http://scigraph.springernature.com/pub.10.1038/jhh.2008.16
DOIhttp://dx.doi.org/10.1038/jhh.2008.16
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1031292409
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/18337755
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Public Health and Health Services",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cardiovascular Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "China",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cohort Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cross-Sectional Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Diabetes Complications",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Follow-Up Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hypercholesterolemia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hypertension",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "India",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Malaysia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prevalence",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Proportional Hazards Models",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Singapore",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Smoking",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "National University of Singapore",
"id": "https://www.grid.ac/institutes/grid.4280.e",
"name": [
"Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "J",
"id": "sg:person.01225125036.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225125036.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Ministry of Health",
"id": "https://www.grid.ac/institutes/grid.415698.7",
"name": [
"Ministry of Health, Singapore"
],
"type": "Organization"
},
"familyName": "Ma",
"givenName": "S",
"id": "sg:person.01244625416.94",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244625416.94"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Ministry of Health",
"id": "https://www.grid.ac/institutes/grid.415698.7",
"name": [
"Ministry of Health, Singapore"
],
"type": "Organization"
},
"familyName": "Heng",
"givenName": "D",
"id": "sg:person.015501727204.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015501727204.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Ministry of Health",
"id": "https://www.grid.ac/institutes/grid.415698.7",
"name": [
"Ministry of Health, Singapore"
],
"type": "Organization"
},
"familyName": "Chew",
"givenName": "S K",
"id": "sg:person.01036072552.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036072552.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National University of Singapore",
"id": "https://www.grid.ac/institutes/grid.4280.e",
"name": [
"Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"
],
"type": "Organization"
},
"familyName": "Hughes",
"givenName": "K",
"id": "sg:person.0632052477.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632052477.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Singapore General Hospital",
"id": "https://www.grid.ac/institutes/grid.163555.1",
"name": [
"Department of Endocrinology, Singapore General Hospital, Singapore"
],
"type": "Organization"
},
"familyName": "Tai",
"givenName": "E S",
"id": "sg:person.012151130377.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012151130377.17"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1097/00004872-200409000-00011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001921050"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200409000-00011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001921050"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1001602",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002649795",
"https://doi.org/10.1038/sj.jhh.1001602"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1001602",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002649795",
"https://doi.org/10.1038/sj.jhh.1001602"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(05)67185-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003174490"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jech.44.1.29",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005948428"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jech.51.4.394",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006258487"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.hyp.33.5.1130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009003596"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/hjh.0b013e3281fc975a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012616091"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/hjh.0b013e3281fc975a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012616091"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.289.19.2560",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013958161"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200018020-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014327092"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200018020-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014327092"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200101000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016896538"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200101000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016896538"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200101000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016896538"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archinte.1993.00410050036006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020205977"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200106000-00021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020882666"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200106000-00021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020882666"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200106000-00021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020882666"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1000949",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021503030",
"https://doi.org/10.1038/sj.jhh.1000949"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1000949",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021503030",
"https://doi.org/10.1038/sj.jhh.1000949"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archinte.161.12.1501",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022667486"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1291/hypres.28.901",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023555650",
"https://doi.org/10.1291/hypres.28.901"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.hjh.0000209973.67746.f0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032337863"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.hjh.0000209973.67746.f0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032337863"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.hjh.0000209973.67746.f0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032337863"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2796.1996.483819000.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034118802"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.amjmed.2005.09.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036047016"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200304000-00013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039134798"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004872-200304000-00013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039134798"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1001683",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039527092",
"https://doi.org/10.1038/sj.jhh.1001683"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1001683",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039527092",
"https://doi.org/10.1038/sj.jhh.1001683"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.jhh.1001683",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039527092",
"https://doi.org/10.1038/sj.jhh.1001683"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jech.44.1.24",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040941009"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm200001063420101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043646406"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(03)12948-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049195365"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(03)12948-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049195365"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/oxfordjournals.aje.a008878",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050157943"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archinte.153.5.598",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054114154"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.amjhyper.2004.06.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054726738"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.amjhyper.2004.12.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054726939"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.amjhyper.2005.03.740",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054727726"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/euhj.1998.1089",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057073803"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.cir.95.5.1132",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063337877"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2337/diacare.22.2.241",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070748635"
],
"type": "CreativeWork"
}
],
"datePublished": "2008-07",
"datePublishedReg": "2008-07-01",
"description": "The current hypertension (HTN) guidelines recommend the assessment of other cardiovascular disease (CVD) risk factors in individuals with HTN for further management. Few studies in Asian populations have been published to identify the outcome of individuals with HTN and other CVD risk factors. This study aims to assess the effect of HTN alone, and in combination with other CVD risk factors on all-cause and CVD mortality. Three cross-sectional studies carried out in Singapore (baseline 1982--1995) consisting of 5830 persons were grouped by the absence or presence of HTN and CVD risk factors. They were followed-up (mean 14.1 years) by linkage with the National Death Register. Cox's proportional hazards model was used to obtain adjusted hazard ratios (HRs) for risk of mortality. HTN individuals with either <2 CVD risk factors (adjusted HR 1.4; 95% confidence interval (CI) 1.0-1.8) or > or =2 CVD risk factors (adjusted HR 2.3; 95% CI 1.9-3.0) were at increased risk of all-cause mortality compared to normotensive individuals. The findings were similar for CVD mortality. HTN individuals who also smoked or had diabetes were at highest risk of all-cause mortality, whereas those with elevated total cholesterol/high-density lipoprotein cholesterol, smoked or diabetes had the highest risk for CVD mortality. These findings show that in HTN individuals it is important to assess the presence of other CVD risk factors and manage accordingly.",
"genre": "research_article",
"id": "sg:pub.10.1038/jhh.2008.16",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1098658",
"issn": [
"0950-9240",
"1476-5527"
],
"name": "Journal of Human Hypertension",
"type": "Periodical"
},
{
"issueNumber": "7",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "22"
}
],
"name": "Hypertension, concurrent cardiovascular risk factors and mortality: the Singapore Cardiovascular Cohort Study",
"pagination": "468",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"9512572bc5f448e99b63f2c46e29ebbe16b0b41a4eec67cbbce30de2757dce00"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"18337755"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"8811625"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/jhh.2008.16"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1031292409"
]
}
],
"sameAs": [
"https://doi.org/10.1038/jhh.2008.16",
"https://app.dimensions.ai/details/publication/pub.1031292409"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T17:19",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000425.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/jhh200816"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/jhh.2008.16'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/jhh.2008.16'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/jhh.2008.16'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/jhh.2008.16'
This table displays all metadata directly associated to this object as RDF triples.
279 TRIPLES
21 PREDICATES
78 URIs
39 LITERALS
27 BLANK NODES