Selection bias in case–control studies on household exposure to pesticides and childhood acute leukemia View Full Text


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Article Info

DATE

2010-06

AUTHORS

Jérémie Rudant, Jacqueline Clavel, Claire Infante-Rivard

ABSTRACT

The goal of this study was to investigate the potential for selection bias in published case-control studies on household exposure to pesticides and childhood acute leukemia; most studies have reported positive findings. Items to evaluate the potential for selection bias were first developed. They focused on the source populations that gave rise to cases and controls, the probabilistic selection of subjects from the source, and the losses of the subjects actually selected. A quantitative assessment of bias was also carried out. Potential sources of selection bias were found in all the studies, but none of them were observed across all the studies. Main sources of potential bias were a non-concurrent selection of controls with respect to cases, the use of control diagnoses possibly caused by pesticide exposure in hospital-based studies, and non-participation of selected eligible subjects. A quantitative assessment of bias concluded that non-participation alone could not explain the reported positive associations. We conclude that overall, selection bias, as a likely source of bias in these studies, does not seem to explain their positive findings. Our analysis provides arguments strengthening the conclusions on associations reported in earlier studies. More... »

PAGES

jes200961

References to SciGraph publications

  • 2000-04. Pesticide storage and use patterns in Minnesota households with children in JOURNAL OF EXPOSURE SCIENCE & ENVIRONMENTAL EPIDEMIOLOGY
  • 2002-04. Day-care, early common infections and childhood acute leukaemia: a multicentre French case–control study in BRITISH JOURNAL OF CANCER
  • 2006-05. Socio-demographic characteristics of UK families using pesticides and weed-killers in JOURNAL OF EXPOSURE SCIENCE & ENVIRONMENTAL EPIDEMIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/jes.2009.61

    DOI

    http://dx.doi.org/10.1038/jes.2009.61

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1001876488

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20010976


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    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/jes.2009.61'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/jes.2009.61'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/jes.2009.61'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/jes.2009.61'


     

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