Amphibian skin microbiota exhibits temporal variation in community structure but stability of predicted Bd-inhibitory function View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-04-07

AUTHORS

Molly C Bletz, R G Bina Perl, Bianca TC Bobowski, Laura M Japke, Christoph C Tebbe, Anja B Dohrmann, Sabin Bhuju, Robert Geffers, Michael Jarek, Miguel Vences

ABSTRACT

Host-associated microbiomes are increasingly recognized to contribute to host disease resistance; the temporal dynamics of their community structure and function, however, are poorly understood. We investigated the cutaneous bacterial communities of three newt species, Ichthyosaura alpestris, Lissotriton vulgaris and Triturus cristatus, at approximately weekly intervals for 3 months using 16S ribosomal RNA amplicon sequencing. We hypothesized cutaneous microbiota would vary across time, and that such variation would be linked to changes in predicted fungal-inhibitory function. We observed significant temporal variation within the aquatic phase, and also between aquatic and terrestrial phase newts. By keeping T. cristatus in mesocosms, we demonstrated that structural changes occurred similarly across individuals, highlighting the non-stochastic nature of the bacterial community succession. Temporal changes were mainly associated with fluctuations in relative abundance rather than full turnover of bacterial operational taxonomic units (OTUs). Newt skin microbe fluctuations were not correlated with that of pond microbiota; however, a portion of community variation was explained by environmental temperature. Using a database of amphibian skin bacteria that inhibit the pathogen Batrachochytrium dendrobatidis (Bd), we found that the proportion of reads associated with ‘potentially’ Bd-inhibitory OTUs did not vary temporally for two of three newt species, suggesting that protective function may be maintained despite temporal variation in community structure. More... »

PAGES

1521-1534

References to SciGraph publications

  • 2012-10-23. Tolerance of fungal infection in European water frogs exposed to Batrachochytrium dendrobatidis after experimental reduction of innate immune defenses in BMC VETERINARY RESEARCH
  • 2010-05-05. A new vision of immunity: homeostasis of the superorganism in MUCOSAL IMMUNOLOGY
  • 2012-06-25. Epithelial antimicrobial defence of the skin and intestine in NATURE REVIEWS IMMUNOLOGY
  • 2014-05-23. Amphibian skin may select for rare environmental microbes in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2011-10-27. Disconnect of microbial structure and function: enzyme activities and bacterial communities in nascent stream corridors in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2011-05-30. Moving pictures of the human microbiome in GENOME BIOLOGY
  • 2016-09-27. Cutaneous Bacterial Communities of a Poisonous Salamander: a Perspective from Life Stages, Body Parts and Environmental Conditions in MICROBIAL ECOLOGY
  • 2013-04-11. A meta-analysis of changes in bacterial and archaeal communities with time in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2016-01-08. Skin bacterial diversity of Panamanian frogs is associated with host susceptibility and presence of Batrachochytrium dendrobatidis in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2007-03-26. The role of microorganisms in coral health, disease and evolution in NATURE REVIEWS MICROBIOLOGY
  • 2014-11-12. Uncoupling of microbial community structure and function in decomposing litter across beech forest ecosystems in Central Europe in SCIENTIFIC REPORTS
  • 2007-10-17. An ecological and evolutionary perspective on human–microbe mutualism and disease in NATURE
  • 2013-12-12. Microbial community dynamics and effect of environmental microbial reservoirs on red-backed salamanders (Plethodon cinereus) in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2013-07-19. Experimental evidence for a cost of resistance to the fungal pathogen, Batrachochytrium dendrobatidis, for the palmate newt, Lissotriton helveticus in BMC ECOLOGY
  • 2014-12-16. Bacteria–bacteria interactions within the microbiota of the ancestral metazoan Hydra contribute to fungal resistance in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2011-03-16. The skin microbiome in NATURE REVIEWS MICROBIOLOGY
  • 2007-05-01. Synchrony in aquatic microbial community dynamics in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2009-03-26. Skin microbes on frogs prevent morbidity and mortality caused by a lethal skin fungus in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2010-04-11. QIIME allows analysis of high-throughput community sequencing data in NATURE METHODS
  • 2011-09-29. Co-habiting amphibian species harbor unique skin bacterial communities in wild populations in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2013-01-01. Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing in NATURE METHODS
  • 2006-01-21. Amphibian Pathogen Batrachochytrium dendrobatidis Is Inhibited by the Cutaneous Bacteria of Amphibian Species in ECOHEALTH
  • 2011-06-24. Metagenomic biomarker discovery and explanation in GENOME BIOLOGY
  • 2015-11-13. Inhibitory bacteria reduce fungi on early life stages of endangered Colorado boreal toads (Anaxyrus boreas) in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2006-10-24. Response of Microbial Community Composition and Function to Soil Climate Change in MICROBIAL ECOLOGY
  • 2012-12-20. Members of native coral microbiota inhibit glycosidases and thwart colonization of coral mucus by an opportunistic pathogen in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2016-12-05. High taxonomic variability despite stable functional structure across microbial communities in NATURE ECOLOGY & EVOLUTION
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    http://scigraph.springernature.com/pub.10.1038/ismej.2017.41

    DOI

    http://dx.doi.org/10.1038/ismej.2017.41

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1084537563

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28387770


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    344 schema:name Genomanalytik, Helmholtz Zentrum für Infektionsforschung, Braunschweig, Germany
    345 rdf:type schema:Organization
     




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