Ontology type: schema:ScholarlyArticle Open Access: True
2015-02-03
AUTHORSJiachao Zhang, Zhuang Guo, Zhengsheng Xue, Zhihong Sun, Menghui Zhang, Lifeng Wang, Guoyang Wang, Fang Wang, Jie Xu, Hongfang Cao, Haiyan Xu, Qiang Lv, Zhi Zhong, Yongfu Chen, Sudu Qimuge, Bilige Menghe, Yi Zheng, Liping Zhao, Wei Chen, Heping Zhang
ABSTRACTStructural profiling of healthy human gut microbiota across heterogeneous populations is necessary for benchmarking and characterizing the potential ecosystem services provided by particular gut symbionts for maintaining the health of their hosts. Here we performed a large structural survey of fecal microbiota in 314 healthy young adults, covering 20 rural and urban cohorts from 7 ethnic groups living in 9 provinces throughout China. Canonical analysis of unweighted UniFrac principal coordinates clustered the subjects mainly by their ethnicities/geography and less so by lifestyles. Nine predominant genera, all of which are known to contain short-chain fatty acid producers, co-occurred in all individuals and collectively represented nearly half of the total sequences. Interestingly, species-level compositional profiles within these nine genera still discriminated the subjects according to their ethnicities/geography and lifestyles. Therefore, a phylogenetically diverse core of gut microbiota at the genus level may be commonly shared by distinctive healthy populations as functionally indispensable ecosystem service providers for the hosts. More... »
PAGES1979-1990
http://scigraph.springernature.com/pub.10.1038/ismej.2015.11
DOIhttp://dx.doi.org/10.1038/ismej.2015.11
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/25647347
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414 TRIPLES
21 PREDICATES
118 URIs
94 LITERALS
29 BLANK NODES