Measles virus causes immunogenic cell death in human melanoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-01

AUTHORS

Oliver G Donnelly, Fiona Errington-Mais, Lynette Steele, Elizabeth Hadac, Victoria Jennings, Karen Scott, Howard Peach, Roger M Phillips, Jacquelyn Bond, Hardev Pandha, Kevin Harrington, Richard Vile, Stephen Russell, Peter Selby, Alan A Melcher

ABSTRACT

Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma. This study demonstrates the efficacy of MV against human melanoma. It is increasingly recognised that an essential component of therapy with OV is the recruitment of host antitumour immune responses, both innate and adaptive. MV-mediated melanoma cell death is an inflammatory process, causing the release of inflammatory cytokines including type-1 interferons and the potent danger signal HMGB1. Here, using human in vitro models, we demonstrate that MV enhances innate antitumour activity, and that MV-mediated melanoma cell death is capable of stimulating a melanoma-specific adaptive immune response. More... »

PAGES

7

References to SciGraph publications

  • 2008-07. HMGB1: Endogenous Danger Signaling in MOLECULAR MEDICINE
  • 2004-10. Toll-like receptor control of the adaptive immune responses in NATURE IMMUNOLOGY
  • 2011-02. Synergistic anti-tumor effects between oncolytic vaccinia virus and paclitaxel are mediated by the IFN response and HMGB1 in GENE THERAPY
  • 2008-10. Chemical control of protein stability and function in living mice in NATURE MEDICINE
  • 2009. Measles Virus-Induced Immunosuppression in MEASLES
  • 2010-08. Demonstration of anti-tumor activity of oncolytic measles virus strains in a malignant pleural effusion breast cancer model in BREAST CANCER RESEARCH AND TREATMENT
  • 2006-01. Fusogenic membrane glycoprotein-mediated tumour cell fusion activates human dendritic cells for enhanced IL-12 production and T-cell priming in GENE THERAPY
  • 2002-07. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation in NATURE
  • 2008-07. Interferon-β therapy for malignant melanoma: the dose is crucial for inhibition of proliferation and induction of apoptosis of melanoma cells in ARCHIVES OF DERMATOLOGICAL RESEARCH
  • 2000-07. Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus in NATURE MEDICINE
  • 2007-04. Three-dimensional culture models of normal and malignant breast epithelial cells in NATURE METHODS
  • 2008-06. Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial in GENE THERAPY
  • 2006-02. Innate immune recognition of viral infection in NATURE IMMUNOLOGY
  • 2010-08. Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy in CANCER GENE THERAPY
  • 2010-03. Local and Distant Immunity Induced by Intralesional Vaccination with an Oncolytic Herpes Virus Encoding GM-CSF in Patients with Stage IIIc and IV Melanoma in ANNALS OF SURGICAL ONCOLOGY
  • 2010-02. Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma in GENE THERAPY
  • 2009. Measles Virus and CD46 in MEASLES
  • 2008-09. Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma in GENE THERAPY
  • 2009-12. Dynamics of multiple myeloma tumor therapy with a recombinant measles virus in CANCER GENE THERAPY
  • 2011-12. Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming in MOLECULAR CANCER
  • 2005-04. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal in NATURE REVIEWS IMMUNOLOGY
  • 2006-11. Recombinant Measles Virus Induces Cytolysis of Cutaneous T-Cell Lymphoma In Vitro and In Vivo in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2007-08-19. Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy in NATURE MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/gt.2011.205

    DOI

    http://dx.doi.org/10.1038/gt.2011.205

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1016314128

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22170342


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