Caregiver opinions about fragile X population screening View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-01

AUTHORS

Donald B. Bailey, Ellen Bishop, Melissa Raspa, Debra Skinner

ABSTRACT

PURPOSE: We sought to determine caregiver perceptions about population screening for fragile X and to examine factors potentially associated with support for screening. METHODS: We asked 1,099 caregivers of a child with fragile X syndrome or a fragile X carrier to rate whether free, voluntary screening should be offered preconception, prenatally, neonatally, or when problems occur. Caregivers chose a preferred time for screening, reported whether screening would affect parent-child bonding, indicated preferences for carrier detection, and gave reasons for their choices. RESULTS: Caregivers endorsed all forms of screening, but prenatal screening was less strongly endorsed than preconception or postnatal screening. Most (79%) preferred preconception carrier testing, allowing more options when making reproductive decisions. Most thought that screening should also disclose carrier status and believed a positive screen would not negatively affect parent-child bonding. Maternal education, caregiver depression, family impact, and severity of disability were not associated with screening opinions, but parents who only had carrier children were less likely to endorse prenatal screening. CONCLUSION: Caregivers of children with fragile X widely endorse screening. However, because different parents will make different choices, screening may need to be offered at multiple times with careful consideration of consent and informed decision-making. More... »

PAGES

115

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/gim.0b013e31822ebaa6

DOI

http://dx.doi.org/10.1038/gim.0b013e31822ebaa6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033474893

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22237440


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