A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-01

AUTHORS

M L Budarf, P Goyette, G Boucher, J Lian, R R Graham, J O Claudio, T Hudson, D Gladman, A E Clarke, J E Pope, C Peschken, C D Smith, J Hanly, E Rich, G Boire, S G Barr, M Zummer, P R Fortin, J Wither, J D Rioux

ABSTRACT

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Multiple genetic and environmental factors contribute to the pathogenesis of this disease. Recent genome-wide association studies have added substantially to the number of genes associated with SLE. To replicate some of these susceptibility loci, single-nucleotide polymorphisms reported to be associated to SLE were evaluated in a cohort of 245 well-phenotyped Canadian SLE trios. Our results replicate previously reported associations to alleles of interferon regulatory factor 5 (IRF5), major histocompatibility complex (MHC), tumor necrosis factor (ligand) superfamily member 4 (TNFSF4), Kell blood group complex subunit-related family member 6 (XKR6), B-cell scaffold protein with ankyrin repeats 1 (BANK1), protein tyrosine phosphatase non-receptor type 22 (PTPN22), ubiquitin-conjugating enzyme E2L 3 (UBE2L3) and islet cell autoantigen 1 (ICA1). We also identify putative associations to cytotoxic T-lymphocyte-associated protein 4 (CTLA4), a gene associated with several autoimmune disorders, and ERBB3, a locus on 12q13 that was previously reported to be associated with type 1 diabetes. This study confirms the existence of multiple genetic risk factors for SLE, and supports the notion that some risk factors for SLE are shared with other inflammatory disorders. More... »

PAGES

51

References to SciGraph publications

  • 2008-02. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus in NATURE GENETICS
  • 2007-07. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility in NATURE GENETICS
  • 2004-05. Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors in NATURE IMMUNOLOGY
  • 2006-10. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC in NATURE GENETICS
  • 2003-05. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease in NATURE
  • 2007-02. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 in NATURE GENETICS
  • 2004-08. Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2001-05. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease in NATURE
  • 2009-01. Detecting shared pathogenesis from the shared genetics of immune-related diseases in NATURE REVIEWS GENETICS
  • 2007-07. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes in NATURE GENETICS
  • 2007-08. Targeting HER proteins in cancer therapy and the role of the non-target HER3 in BRITISH JOURNAL OF CANCER
  • 2009-11. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus in NATURE GENETICS
  • 2008-09. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus in NATURE GENETICS
  • 2008-08. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease in NATURE GENETICS
  • 2007-06-07. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls in NATURE
  • 2007-07. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 in NATURE GENETICS
  • 2006-05. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus in NATURE GENETICS
  • 2001-10. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease in NATURE GENETICS
  • 2007-05. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis in NATURE GENETICS
  • 2001-05. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease in NATURE
  • 2007-09. Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus in NATURE GENETICS
  • 2008-02. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci in NATURE GENETICS
  • 2009-11. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus in NATURE GENETICS
  • 2008-01. Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus in NATURE GENETICS
  • 2009-07. Recent insights into the genetic basis of systemic lupus erythematosus in GENES & IMMUNITY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/gene.2010.47

    DOI

    http://dx.doi.org/10.1038/gene.2010.47

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002800222

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20962850


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