Monitoring propranolol treatment in periocular infantile haemangioma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-11

AUTHORS

R Burne, R Taylor

ABSTRACT

OBJECTIVE: To develop a tool for assessing amblyopic risk and monitoring the treatment effect of propranolol in periocular haemangioma management. METHODS: We present a study of nine children with periocular haemangioma who underwent propranolol treatment at York Hospital between 2009 and 2013.A proposed measure of amblyogenic risk based on the induced anisometropia resulting from a periocular haemangioma was calculated in the form of a single quantitative value, measured in dioptres. This calculation used published work and developed it to produce a new function, termed the delta defocus equivalent (DFE-∂).Refraction measurements were retrospectively collected from patients' notes in order to measure the trend of DFE-∂ over the treatment period with propranolol. RESULTS: The average DFE-∂ at commencement of propranolol was 1.54 (±0.62) D. The average at the end of treatment was 0.39 (±0.38) D. CONCLUSION: This work presents a possible tool for assessing amblyopic risk in cases of periocular infantile haemangioma. The DFE-∂ gives a measure in dioptres, which may represent the true amblyopic risk, and so be useful in supporting treatment decisions in paediatric ophthalmology. More... »

PAGES

1281-1285

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/eye.2014.237

DOI

http://dx.doi.org/10.1038/eye.2014.237

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043249771

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25323853


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