IL-17 cytokines in immunity and inflammation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-09

AUTHORS

Wei Jin, Chen Dong

ABSTRACT

Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In this review, we summarize the recent findings in IL-17 biology and the progress towards understanding the regulatory mechanisms of IL-17 expression and signaling mechanisms. This knowledge will benefit the development of novel immune modulators that enhance immunity to various infections and reduce inflammatory damage in infected patients. More... »

PAGES

e60

References to SciGraph publications

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  • Journal

    TITLE

    Emerging Microbes & Infections

    ISSUE

    9

    VOLUME

    2

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/emi.2013.58

    DOI

    http://dx.doi.org/10.1038/emi.2013.58

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015943835

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26038490


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