Interleukin 18 receptor 1 gene polymorphisms are associated with asthma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-09

AUTHORS

Guohua Zhu, Moira K B Whyte, Jorgen Vestbo, Karin Carlsen, Kai-Håkon Carlsen, Warren Lenney, Michael Silverman, Peter Helms, Sreekumar G Pillai

ABSTRACT

The interleukin 18 receptor (IL18R1) gene is a strong candidate gene for asthma. It has been implicated in the pathophysiology of asthma and maps to an asthma susceptibility locus on chromosome 2q12. The possibility of association between polymorphisms in IL18R1 and asthma was examined by genotyping seven SNPs in 294, 342 and 100 families from Denmark, United Kingdom and Norway and conducting family-based association analyses for asthma, atopic asthma and bronchial hyper-reactivity (BHR) phenotypes. Three SNPs in IL18R1 were associated with asthma (0.01131 < or = P < or = 0.01377), five with atopic asthma (0.00066 < or = P < or = 0.00405) and two with BHR (0.01450 < or = P < or = 0.03203) in the Danish population; two SNPs were associated with atopic asthma (0.00397 < or = P < or = 0.01481) and four with BHR (0.00435 < or = P < or = 0.03544) in the UK population; four SNPs showed associations with asthma (0.00015 < or = P < or = 0.03062), two with atopic asthma (0.01269 < or = P < or = 0.04042) and three with BHR (0.00259 < or = P < or = 0.01401) in the Norwegian population; five SNPs showed associations with asthma (0.00005 < or = P < or = 0.03744), five with atopic asthma (0.00001 < or = P < or = 0.04491) and three with BHR (0.03568 < or = P < or = 0.04778) in the combined population. Three intronic SNPs (rs1420099, rs1362348 and rs1974675) showed replicated association for at least one asthma-related phenotype. These results demonstrate significant association between polymorphisms in IL18R1 and asthma. More... »

PAGES

ejhg200867

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ejhg.2008.67

DOI

http://dx.doi.org/10.1038/ejhg.2008.67

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019119266

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18382474


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Asthma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Denmark", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Markers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haplotypes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interleukin-18 Receptor alpha Subunit", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Norway", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "United Kingdom", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "GlaxoSmithKline (United States)", 
          "id": "https://www.grid.ac/institutes/grid.418019.5", 
          "name": [
            "Genetics, GlaxoSmithKline, Research Triangle Park, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhu", 
        "givenName": "Guohua", 
        "id": "sg:person.01350001260.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350001260.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sheffield", 
          "id": "https://www.grid.ac/institutes/grid.11835.3e", 
          "name": [
            "Academic Unit of Respiratory Medicine, University of Sheffield, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Whyte", 
        "givenName": "Moira K B", 
        "id": "sg:person.012354533232.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012354533232.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hvidovre Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411905.8", 
          "name": [
            "Institute of Preventive Medicine, Kommunehospitalet, Copenhagen, Denmark", 
            "Department of Respiratory Medicine, Hvidovre University Hospital, Hvidovre, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vestbo", 
        "givenName": "Jorgen", 
        "id": "sg:person.0734042544.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734042544.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Oslo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.55325.34", 
          "name": [
            "Department of Pediatrics, Ullevaal University Hospital, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Carlsen", 
        "givenName": "Karin", 
        "id": "sg:person.012050133702.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012050133702.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Oslo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.55325.34", 
          "name": [
            "Department of Pediatrics, Ullevaal University Hospital, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Carlsen", 
        "givenName": "Kai-H\u00e5kon", 
        "id": "sg:person.013260533102.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013260533102.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Stoke University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.439344.d", 
          "name": [
            "Directorate of Child Health, Academic Department of Pediatrics, North Staffordshire Hospital, Stoke-on-Trent, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lenney", 
        "givenName": "Warren", 
        "id": "sg:person.01251716115.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251716115.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Leicester", 
          "id": "https://www.grid.ac/institutes/grid.9918.9", 
          "name": [
            "Division of Child Health, University of Leicester, Leicester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Silverman", 
        "givenName": "Michael", 
        "id": "sg:person.01011672751.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011672751.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Aberdeen Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416072.6", 
          "name": [
            "Department of Child Health, University of Aberdeen Royal Aberdeen Children's Hospital, Aberdeen, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Helms", 
        "givenName": "Peter", 
        "id": "sg:person.0636023040.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636023040.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "GlaxoSmithKline (United States)", 
          "id": "https://www.grid.ac/institutes/grid.418019.5", 
          "name": [
            "Genetics, GlaxoSmithKline, Research Triangle Park, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pillai", 
        "givenName": "Sreekumar G", 
        "id": "sg:person.01141130551.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141130551.53"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.gene.6364366", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002678409", 
          "https://doi.org/10.1038/sj.gene.6364366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6364366", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002678409", 
          "https://doi.org/10.1038/sj.gene.6364366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1744-313x.2006.00631.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006688288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bth457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008081196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.00031506", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009825388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1069424", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010139737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1999.5767", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010934720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9297(07)62946-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012441523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200102013440507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013736663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gepi.10295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013998858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.519702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014524096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mai.2002.122158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014887719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1398-9995.2004.00538.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015299188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1999.5806", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015738423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6364399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016129678", 
          "https://doi.org/10.1038/sj.gene.6364399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1359-6446(04)03321-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018585593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ejhg.5201532", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020320737", 
          "https://doi.org/10.1038/sj.ejhg.5201532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ejhg.5201532", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020320737", 
          "https://doi.org/10.1038/sj.ejhg.5201532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1398-9995.2005.00619.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025112226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1398-9995.2005.00619.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025112226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/7.9.1393", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025578066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ejhg.5200625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026220336", 
          "https://doi.org/10.1038/sj.ejhg.5200625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ejhg.5200625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026220336", 
          "https://doi.org/10.1038/sj.ejhg.5200625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1998.8236", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026748748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1165/ajrcmb.22.6.f191", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026778081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.immunol.19.1.423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028158775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-7613(00)80596-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028440125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1997.6665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029433408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2370.2004.00441.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029792759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0091-6749(99)70518-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040364088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0091-6749(99)70518-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040364088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.272.41.25737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040517762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.162.4.9909031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041072973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/77811", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045983463", 
          "https://doi.org/10.1038/77811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/77811", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045983463", 
          "https://doi.org/10.1038/77811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2005.04.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047137330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2222.2003.01739.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047450651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.2000.00836.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047464838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.2000.00836.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047464838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047659846", 
          "https://doi.org/10.1038/ng1071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047659846", 
          "https://doi.org/10.1038/ng1071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6364284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048759804", 
          "https://doi.org/10.1038/sj.gene.6364284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6364284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048759804", 
          "https://doi.org/10.1038/sj.gene.6364284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-3083.2000.00836.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056737871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/301904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058609501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/321191", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058623409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/381000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058673096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/429864", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058716362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00008571-200409000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060290148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00008571-200409000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060290148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00008571-200409000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060290148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074367336", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074367341", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.178.3.1948", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077353737"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-09", 
    "datePublishedReg": "2008-09-01", 
    "description": "The interleukin 18 receptor (IL18R1) gene is a strong candidate gene for asthma. It has been implicated in the pathophysiology of asthma and maps to an asthma susceptibility locus on chromosome 2q12. The possibility of association between polymorphisms in IL18R1 and asthma was examined by genotyping seven SNPs in 294, 342 and 100 families from Denmark, United Kingdom and Norway and conducting family-based association analyses for asthma, atopic asthma and bronchial hyper-reactivity (BHR) phenotypes. Three SNPs in IL18R1 were associated with asthma (0.01131 < or = P < or = 0.01377), five with atopic asthma (0.00066 < or = P < or = 0.00405) and two with BHR (0.01450 < or = P < or = 0.03203) in the Danish population; two SNPs were associated with atopic asthma (0.00397 < or = P < or = 0.01481) and four with BHR (0.00435 < or = P < or = 0.03544) in the UK population; four SNPs showed associations with asthma (0.00015 < or = P < or = 0.03062), two with atopic asthma (0.01269 < or = P < or = 0.04042) and three with BHR (0.00259 < or = P < or = 0.01401) in the Norwegian population; five SNPs showed associations with asthma (0.00005 < or = P < or = 0.03744), five with atopic asthma (0.00001 < or = P < or = 0.04491) and three with BHR (0.03568 < or = P < or = 0.04778) in the combined population. Three intronic SNPs (rs1420099, rs1362348 and rs1974675) showed replicated association for at least one asthma-related phenotype. These results demonstrate significant association between polymorphisms in IL18R1 and asthma.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ejhg.2008.67", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1103410", 
        "issn": [
          "1018-4813", 
          "1476-5438"
        ], 
        "name": "European Journal of Human Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "Interleukin 18 receptor 1 gene polymorphisms are associated with asthma", 
    "pagination": "ejhg200867", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5b18771be3c070e135223a68f0370ce6147a5f37ff4c6f52d569bf46e2b88eaf"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18382474"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9302235"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ejhg.2008.67"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019119266"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ejhg.2008.67", 
      "https://app.dimensions.ai/details/publication/pub.1019119266"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000424.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/ejhg200867"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ejhg.2008.67'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ejhg.2008.67'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ejhg.2008.67'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ejhg.2008.67'


 

This table displays all metadata directly associated to this object as RDF triples.

334 TRIPLES      21 PREDICATES      86 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ejhg.2008.67 schema:about N009f95f36cfa4fe089de018514bcb70d
2 N221c4ef7e9504b3aadd016b2f4dac6fd
3 N3b05bfbbd8604c99b4801005c7b76516
4 N518683fc306145409280fc3c56f20458
5 N5daba395524549789c28611531841caf
6 N67aa0d7dc233474c8b252510dfb99e0a
7 N75c15c9741b24704b112b83fd355cac4
8 N88d9ed0f9cc647ea86c9532825ca9f24
9 N95a777c910924bf79a0ea071b0fbbc15
10 Na4dbf237467a43a4b28bc5122b154214
11 Nae1d45e69dbc4889985df0100fe7be4e
12 Nd1bbcfab4e4c45a38d986082f68d3540
13 Nde7f2fa119604ef1b0f839352fb8414d
14 Ne09bc4ae97714967b6e0e5d93fc4cf5b
15 anzsrc-for:11
16 anzsrc-for:1102
17 schema:author N95a27f3e9a2d451e950cc1e2bcc0235b
18 schema:citation sg:pub.10.1038/77811
19 sg:pub.10.1038/ng1071
20 sg:pub.10.1038/sj.ejhg.5200625
21 sg:pub.10.1038/sj.ejhg.5201532
22 sg:pub.10.1038/sj.gene.6364284
23 sg:pub.10.1038/sj.gene.6364366
24 sg:pub.10.1038/sj.gene.6364399
25 https://app.dimensions.ai/details/publication/pub.1074367336
26 https://app.dimensions.ai/details/publication/pub.1074367341
27 https://doi.org/10.1002/gepi.10295
28 https://doi.org/10.1006/bbrc.1997.6665
29 https://doi.org/10.1006/bbrc.1998.8236
30 https://doi.org/10.1006/geno.1999.5767
31 https://doi.org/10.1006/geno.1999.5806
32 https://doi.org/10.1016/j.jaci.2005.04.039
33 https://doi.org/10.1016/s0002-9297(07)62946-2
34 https://doi.org/10.1016/s0091-6749(99)70518-x
35 https://doi.org/10.1016/s1074-7613(00)80596-8
36 https://doi.org/10.1016/s1359-6446(04)03321-5
37 https://doi.org/10.1046/j.1365-2222.2003.01739.x
38 https://doi.org/10.1046/j.1365-3083.2000.00836.x
39 https://doi.org/10.1056/nejm200102013440507
40 https://doi.org/10.1067/mai.2002.122158
41 https://doi.org/10.1074/jbc.272.41.25737
42 https://doi.org/10.1086/301904
43 https://doi.org/10.1086/321191
44 https://doi.org/10.1086/381000
45 https://doi.org/10.1086/429864
46 https://doi.org/10.1093/bioinformatics/bth457
47 https://doi.org/10.1093/hmg/7.9.1393
48 https://doi.org/10.1097/00008571-200409000-00007
49 https://doi.org/10.1111/j.1365-2370.2004.00441.x
50 https://doi.org/10.1111/j.1365-3083.2000.00836.x
51 https://doi.org/10.1111/j.1398-9995.2004.00538.x
52 https://doi.org/10.1111/j.1398-9995.2005.00619.x
53 https://doi.org/10.1111/j.1744-313x.2006.00631.x
54 https://doi.org/10.1126/science.1069424
55 https://doi.org/10.1146/annurev.immunol.19.1.423
56 https://doi.org/10.1161/circulationaha.104.519702
57 https://doi.org/10.1164/ajrccm.162.4.9909031
58 https://doi.org/10.1165/ajrcmb.22.6.f191
59 https://doi.org/10.1183/09031936.00031506
60 https://doi.org/10.4049/jimmunol.178.3.1948
61 schema:datePublished 2008-09
62 schema:datePublishedReg 2008-09-01
63 schema:description The interleukin 18 receptor (IL18R1) gene is a strong candidate gene for asthma. It has been implicated in the pathophysiology of asthma and maps to an asthma susceptibility locus on chromosome 2q12. The possibility of association between polymorphisms in IL18R1 and asthma was examined by genotyping seven SNPs in 294, 342 and 100 families from Denmark, United Kingdom and Norway and conducting family-based association analyses for asthma, atopic asthma and bronchial hyper-reactivity (BHR) phenotypes. Three SNPs in IL18R1 were associated with asthma (0.01131 < or = P < or = 0.01377), five with atopic asthma (0.00066 < or = P < or = 0.00405) and two with BHR (0.01450 < or = P < or = 0.03203) in the Danish population; two SNPs were associated with atopic asthma (0.00397 < or = P < or = 0.01481) and four with BHR (0.00435 < or = P < or = 0.03544) in the UK population; four SNPs showed associations with asthma (0.00015 < or = P < or = 0.03062), two with atopic asthma (0.01269 < or = P < or = 0.04042) and three with BHR (0.00259 < or = P < or = 0.01401) in the Norwegian population; five SNPs showed associations with asthma (0.00005 < or = P < or = 0.03744), five with atopic asthma (0.00001 < or = P < or = 0.04491) and three with BHR (0.03568 < or = P < or = 0.04778) in the combined population. Three intronic SNPs (rs1420099, rs1362348 and rs1974675) showed replicated association for at least one asthma-related phenotype. These results demonstrate significant association between polymorphisms in IL18R1 and asthma.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree true
67 schema:isPartOf Nb9f0724256f644eda2eed64700893900
68 Nff87e2196c3a49fbbadcb2ee06d9e3fd
69 sg:journal.1103410
70 schema:name Interleukin 18 receptor 1 gene polymorphisms are associated with asthma
71 schema:pagination ejhg200867
72 schema:productId N0df3a079a09845fcb7c96916f8d683e8
73 N20a5a22e95fe464d81c8b7e253ee1e0a
74 N62573d9749b5432193788eb6c5d23f97
75 Na8697779974e4052b06388e176ddcf0e
76 Ne4f8a91f4ebe4f3fba9482284e1ba61e
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019119266
78 https://doi.org/10.1038/ejhg.2008.67
79 schema:sdDatePublished 2019-04-10T18:56
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher N0bab6b9eee4c4a41a81f223d641c5e88
82 schema:url http://www.nature.com/articles/ejhg200867
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N009f95f36cfa4fe089de018514bcb70d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Adolescent
88 rdf:type schema:DefinedTerm
89 N0bab6b9eee4c4a41a81f223d641c5e88 schema:name Springer Nature - SN SciGraph project
90 rdf:type schema:Organization
91 N0df3a079a09845fcb7c96916f8d683e8 schema:name nlm_unique_id
92 schema:value 9302235
93 rdf:type schema:PropertyValue
94 N20a5a22e95fe464d81c8b7e253ee1e0a schema:name pubmed_id
95 schema:value 18382474
96 rdf:type schema:PropertyValue
97 N221c4ef7e9504b3aadd016b2f4dac6fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Norway
99 rdf:type schema:DefinedTerm
100 N385fde57840540b4a05013daa349de76 rdf:first sg:person.012354533232.13
101 rdf:rest N55f1681ee5cb4bb5834646526057d518
102 N3b05bfbbd8604c99b4801005c7b76516 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Genetic Markers
104 rdf:type schema:DefinedTerm
105 N518683fc306145409280fc3c56f20458 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Middle Aged
107 rdf:type schema:DefinedTerm
108 N55f1681ee5cb4bb5834646526057d518 rdf:first sg:person.0734042544.03
109 rdf:rest N9d8edcbe1e8646a3bc8728e0d5ac2b56
110 N5c80b4fddba44a6e9606a5400d0d8482 rdf:first sg:person.0636023040.07
111 rdf:rest Ne02f7e72154b4e8b869e68b8ef2f812b
112 N5daba395524549789c28611531841caf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Humans
114 rdf:type schema:DefinedTerm
115 N62573d9749b5432193788eb6c5d23f97 schema:name doi
116 schema:value 10.1038/ejhg.2008.67
117 rdf:type schema:PropertyValue
118 N67aa0d7dc233474c8b252510dfb99e0a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Female
120 rdf:type schema:DefinedTerm
121 N75c15c9741b24704b112b83fd355cac4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Asthma
123 rdf:type schema:DefinedTerm
124 N88d9ed0f9cc647ea86c9532825ca9f24 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Adult
126 rdf:type schema:DefinedTerm
127 N95a27f3e9a2d451e950cc1e2bcc0235b rdf:first sg:person.01350001260.48
128 rdf:rest N385fde57840540b4a05013daa349de76
129 N95a777c910924bf79a0ea071b0fbbc15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name United Kingdom
131 rdf:type schema:DefinedTerm
132 N9d8edcbe1e8646a3bc8728e0d5ac2b56 rdf:first sg:person.012050133702.15
133 rdf:rest Nfabade19b0394a3badeb5044afae6d71
134 Na4dbf237467a43a4b28bc5122b154214 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Interleukin-18 Receptor alpha Subunit
136 rdf:type schema:DefinedTerm
137 Na8697779974e4052b06388e176ddcf0e schema:name dimensions_id
138 schema:value pub.1019119266
139 rdf:type schema:PropertyValue
140 Nae1d45e69dbc4889985df0100fe7be4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Polymorphism, Single Nucleotide
142 rdf:type schema:DefinedTerm
143 Nb70879e596f346b68ceda31ed85af254 rdf:first sg:person.01011672751.26
144 rdf:rest N5c80b4fddba44a6e9606a5400d0d8482
145 Nb9f0724256f644eda2eed64700893900 schema:issueNumber 9
146 rdf:type schema:PublicationIssue
147 Nbd5b8f32be9a46fd8233f27564df8a3a rdf:first sg:person.01251716115.62
148 rdf:rest Nb70879e596f346b68ceda31ed85af254
149 Nd1bbcfab4e4c45a38d986082f68d3540 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Denmark
151 rdf:type schema:DefinedTerm
152 Nde7f2fa119604ef1b0f839352fb8414d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Haplotypes
154 rdf:type schema:DefinedTerm
155 Ne02f7e72154b4e8b869e68b8ef2f812b rdf:first sg:person.01141130551.53
156 rdf:rest rdf:nil
157 Ne09bc4ae97714967b6e0e5d93fc4cf5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Male
159 rdf:type schema:DefinedTerm
160 Ne4f8a91f4ebe4f3fba9482284e1ba61e schema:name readcube_id
161 schema:value 5b18771be3c070e135223a68f0370ce6147a5f37ff4c6f52d569bf46e2b88eaf
162 rdf:type schema:PropertyValue
163 Nfabade19b0394a3badeb5044afae6d71 rdf:first sg:person.013260533102.40
164 rdf:rest Nbd5b8f32be9a46fd8233f27564df8a3a
165 Nff87e2196c3a49fbbadcb2ee06d9e3fd schema:volumeNumber 16
166 rdf:type schema:PublicationVolume
167 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
168 schema:name Medical and Health Sciences
169 rdf:type schema:DefinedTerm
170 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
171 schema:name Cardiorespiratory Medicine and Haematology
172 rdf:type schema:DefinedTerm
173 sg:journal.1103410 schema:issn 1018-4813
174 1476-5438
175 schema:name European Journal of Human Genetics
176 rdf:type schema:Periodical
177 sg:person.01011672751.26 schema:affiliation https://www.grid.ac/institutes/grid.9918.9
178 schema:familyName Silverman
179 schema:givenName Michael
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011672751.26
181 rdf:type schema:Person
182 sg:person.01141130551.53 schema:affiliation https://www.grid.ac/institutes/grid.418019.5
183 schema:familyName Pillai
184 schema:givenName Sreekumar G
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141130551.53
186 rdf:type schema:Person
187 sg:person.012050133702.15 schema:affiliation https://www.grid.ac/institutes/grid.55325.34
188 schema:familyName Carlsen
189 schema:givenName Karin
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012050133702.15
191 rdf:type schema:Person
192 sg:person.012354533232.13 schema:affiliation https://www.grid.ac/institutes/grid.11835.3e
193 schema:familyName Whyte
194 schema:givenName Moira K B
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012354533232.13
196 rdf:type schema:Person
197 sg:person.01251716115.62 schema:affiliation https://www.grid.ac/institutes/grid.439344.d
198 schema:familyName Lenney
199 schema:givenName Warren
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251716115.62
201 rdf:type schema:Person
202 sg:person.013260533102.40 schema:affiliation https://www.grid.ac/institutes/grid.55325.34
203 schema:familyName Carlsen
204 schema:givenName Kai-Håkon
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013260533102.40
206 rdf:type schema:Person
207 sg:person.01350001260.48 schema:affiliation https://www.grid.ac/institutes/grid.418019.5
208 schema:familyName Zhu
209 schema:givenName Guohua
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350001260.48
211 rdf:type schema:Person
212 sg:person.0636023040.07 schema:affiliation https://www.grid.ac/institutes/grid.416072.6
213 schema:familyName Helms
214 schema:givenName Peter
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636023040.07
216 rdf:type schema:Person
217 sg:person.0734042544.03 schema:affiliation https://www.grid.ac/institutes/grid.411905.8
218 schema:familyName Vestbo
219 schema:givenName Jorgen
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734042544.03
221 rdf:type schema:Person
222 sg:pub.10.1038/77811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045983463
223 https://doi.org/10.1038/77811
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/ng1071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047659846
226 https://doi.org/10.1038/ng1071
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/sj.ejhg.5200625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026220336
229 https://doi.org/10.1038/sj.ejhg.5200625
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/sj.ejhg.5201532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020320737
232 https://doi.org/10.1038/sj.ejhg.5201532
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/sj.gene.6364284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048759804
235 https://doi.org/10.1038/sj.gene.6364284
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/sj.gene.6364366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002678409
238 https://doi.org/10.1038/sj.gene.6364366
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/sj.gene.6364399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016129678
241 https://doi.org/10.1038/sj.gene.6364399
242 rdf:type schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1074367336 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1074367341 schema:CreativeWork
245 https://doi.org/10.1002/gepi.10295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013998858
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1006/bbrc.1997.6665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029433408
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1006/bbrc.1998.8236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026748748
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1006/geno.1999.5767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010934720
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1006/geno.1999.5806 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015738423
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/j.jaci.2005.04.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047137330
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0002-9297(07)62946-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012441523
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s0091-6749(99)70518-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040364088
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/s1074-7613(00)80596-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028440125
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s1359-6446(04)03321-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018585593
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1046/j.1365-2222.2003.01739.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047450651
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1046/j.1365-3083.2000.00836.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1056737871
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1056/nejm200102013440507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013736663
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1067/mai.2002.122158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014887719
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1074/jbc.272.41.25737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040517762
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1086/301904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058609501
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1086/321191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058623409
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1086/381000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058673096
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1086/429864 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058716362
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1093/bioinformatics/bth457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008081196
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1093/hmg/7.9.1393 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025578066
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1097/00008571-200409000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060290148
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1111/j.1365-2370.2004.00441.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029792759
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1111/j.1365-3083.2000.00836.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047464838
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1111/j.1398-9995.2004.00538.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015299188
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1111/j.1398-9995.2005.00619.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025112226
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1111/j.1744-313x.2006.00631.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006688288
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1126/science.1069424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010139737
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1146/annurev.immunol.19.1.423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028158775
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1161/circulationaha.104.519702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014524096
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1164/ajrccm.162.4.9909031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041072973
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1165/ajrcmb.22.6.f191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026778081
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1183/09031936.00031506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009825388
310 rdf:type schema:CreativeWork
311 https://doi.org/10.4049/jimmunol.178.3.1948 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077353737
312 rdf:type schema:CreativeWork
313 https://www.grid.ac/institutes/grid.11835.3e schema:alternateName University of Sheffield
314 schema:name Academic Unit of Respiratory Medicine, University of Sheffield, Sheffield, UK
315 rdf:type schema:Organization
316 https://www.grid.ac/institutes/grid.411905.8 schema:alternateName Hvidovre Hospital
317 schema:name Department of Respiratory Medicine, Hvidovre University Hospital, Hvidovre, Denmark
318 Institute of Preventive Medicine, Kommunehospitalet, Copenhagen, Denmark
319 rdf:type schema:Organization
320 https://www.grid.ac/institutes/grid.416072.6 schema:alternateName Royal Aberdeen Children's Hospital
321 schema:name Department of Child Health, University of Aberdeen Royal Aberdeen Children's Hospital, Aberdeen, UK
322 rdf:type schema:Organization
323 https://www.grid.ac/institutes/grid.418019.5 schema:alternateName GlaxoSmithKline (United States)
324 schema:name Genetics, GlaxoSmithKline, Research Triangle Park, NC, USA
325 rdf:type schema:Organization
326 https://www.grid.ac/institutes/grid.439344.d schema:alternateName Royal Stoke University Hospital
327 schema:name Directorate of Child Health, Academic Department of Pediatrics, North Staffordshire Hospital, Stoke-on-Trent, UK
328 rdf:type schema:Organization
329 https://www.grid.ac/institutes/grid.55325.34 schema:alternateName Oslo University Hospital
330 schema:name Department of Pediatrics, Ullevaal University Hospital, Oslo, Norway
331 rdf:type schema:Organization
332 https://www.grid.ac/institutes/grid.9918.9 schema:alternateName University of Leicester
333 schema:name Division of Child Health, University of Leicester, Leicester, UK
334 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...