Double-blind, placebo-controlled pilot trial of anthocyanin-rich purple sweet potato beverage on serum hepatic biomarker levels in healthy Caucasians with borderline ... View Full Text


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Article Info

DATE

2017-02

AUTHORS

T Oki, M Kano, F Ishikawa, K Goto, O Watanabe, I Suda

ABSTRACT

The objective is to evaluate the efficacy of anthocyanin-rich purple-fleshed sweet potato (PSP) beverage on the serum levels of gamma-glutamyl transferase (GGT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in healthy Caucasians with borderline hepatitis. Forty healthy Caucasians (41-69 years) consumed three bottles of the PSP beverage (177 mg anthocyanins per 125-ml bottle) or placebo (1.3 mg) per day for 8 weeks. Thirty-nine subjects completed the study and two subjects were excluded from statistical analysis. GGT levels in the PSP group on days 15 and 43 were lower (P=0.077 and 0.038, respectively), AST levels in the PSP group on days 29 and 43 were lower (P=0.010 and 0.045, respectively) and ALT level in the PSP group on day 43 was lower (P=0.037) than in the placebo group. The PSP beverage did not induce clinically relevant changes in other blood and clinical chemistry parameters. More... »

PAGES

290

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ejcn.2016.153

DOI

http://dx.doi.org/10.1038/ejcn.2016.153

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014025460

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27530473


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