Dietary antioxidant capacity and concentration of adiponectin in apparently healthy adults: the ATTICA study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-02

AUTHORS

P Detopoulou, D B Panagiotakos, C Chrysohoou, E Fragopoulou, T Nomikos, S Antonopoulou, C Pitsavos, C Stefanadis

ABSTRACT

BACKGROUND/OBJECTIVES: This study aimed at evaluating the relationship of adiponectin concentration with total dietary antioxidant capacity in free-living, apparently healthy adults from the ATTICA study. SUBJECTS/METHODS: A random subsample from the ATTICA study, consisting of 310 men (40+/-11 years) and 222 women (38+/-12 years), was selected. Adiponectin, along with other inflammatory markers, was measured in fasting participants. Dietary habits were evaluated using a food frequency questionnaire and the dietary antioxidant capacity was based on published values of Italian foods measured by three different assays: ferric-reducing antioxidant power (FRAP), total radical-trapping antioxidant parameters (TRAP) and trolox-equivalent antioxidant capacity (TEAC). RESULTS: Positive associations were observed between dietary antioxidant capacity and adiponectin concentration, as assessed with FRAP (b+/-s.e.=0.012+/-0.005, P=0.018 per 1 mmol Fe (II)/day), TRAP (b+/-s.e.=0.030+/-0.013, P=0.017 per 1 mmol trolox equivalent/day) and TEAC (b+/-s.e.=0.025+/-0.012, P=0.042, per 1 mmol trolox equivalent/day) in multiadjusted analysis. Moreover, a negative relation of dietary antioxidant indices with inflammatory markers was revealed. CONCLUSIONS: Diets with high antioxidant capacity are related to increased adiponectin levels. An adiponectin-mediated route through which antioxidant-rich foods exert beneficial effects against inflammation and cardiovascular diseases can be thus hypothesized. More... »

PAGES

ejcn2009130

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ejcn.2009.130

DOI

http://dx.doi.org/10.1038/ejcn.2009.130

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044593126

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19904292


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