Breast feeding in infancy and arterial endothelial function later in life. The Cardiovascular Risk in Young Finns Study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-02-20

AUTHORS

M J Järvisalo, N Hutri-Kähönen, M Juonala, V Mikkilä, L Räsänen, T Lehtimäki, J Viikari, O T Raitakari

ABSTRACT

Background/Objectives:Breast feeding in infancy may be associated with reduced cardiovascular morbidity in adulthood. We examined the association between breast feeding in infancy and arterial function and structure in adulthood in a population-based cohort of Finnish adults.Subjects/Methods:Noninvasive ultrasound was used to measure brachial artery flow-mediated dilatation (FMD), carotid artery intima-media thickness (IMT) and carotid artery compliance (CAC) in 1667 young adults participating in the Cardiovascular Risk in Young Finns Study with data on early nutrition.Results:Maximal FMD was higher in breast-fed men compared to formula-fed men (7.2±4.0 vs 5.9±3.4%, P=0.029) while no differences were seen between breast-fed and formula-fed women (8.9±4.5 vs 8.8±5.0%, P=0.84). In men, the multivariable correlates of FMD included the group variable for breast feeding (P=0.014), birth weight (P=0.043), waist circumference (P<0.001) and baseline brachial artery diameter (P<0.001). In women, the multivariable correlates of FMD were birth weight (P=0.02), waist circumference (P<0.001) and brachial artery baseline diameter (P<0.001). Breast feeding was not significantly associated with IMT or CAC in multivariable models.Conclusions:Adult men who have been breast fed have better brachial endothelial function compared to men who have been formula fed. More... »

PAGES

640-645

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ejcn.2008.17

DOI

http://dx.doi.org/10.1038/ejcn.2008.17

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041637646

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18285807


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