Mechanisms of apoptotic phosphatidylserine exposure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-11

AUTHORS

Guillermo Mariño, Guido Kroemer

ABSTRACT

It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells. More... »

PAGES

1247

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/cr.2013.115

DOI

http://dx.doi.org/10.1038/cr.2013.115

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037332180

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23979019


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Membrane", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phospholipid Transfer Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phospholipids", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Paris Descartes University", 
          "id": "https://www.grid.ac/institutes/grid.10992.33", 
          "name": [
            "INSERM, U848, F-94805 Villejuif, France", 
            "Universit\u00e9 Paris Descartes/Paris V, Sorbonne Paris Cit\u00e9, 75006 Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mari\u00f1o", 
        "givenName": "Guillermo", 
        "id": "sg:person.0765732226.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765732226.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM, U848, F-94805 Villejuif, France", 
            "Universit\u00e9 Paris Descartes/Paris V, Sorbonne Paris Cit\u00e9, 75006 Paris, France", 
            "Equipe 11 labellis\u00e9e par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, F-75006 Paris, France", 
            "P\u00f4le de Biologie, H\u00f4pital Europ\u00e9en Georges Pompidou, AP-HP, F-75015 Paris, France", 
            "Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, F-94805 Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kroemer", 
        "givenName": "Guido", 
        "id": "sg:person.0610375740.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610375740.57"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s1097-2765(00)80437-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009229085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1236758", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019935444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.biophys.093008.131234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026305745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09583", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027963928", 
          "https://doi.org/10.1038/nature09583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09583", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027963928", 
          "https://doi.org/10.1038/nature09583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/17135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031480889", 
          "https://doi.org/10.1038/17135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/17135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031480889", 
          "https://doi.org/10.1038/17135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032804444", 
          "https://doi.org/10.1038/ncb1574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032804444", 
          "https://doi.org/10.1038/ncb1574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11240", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047562121", 
          "https://doi.org/10.1038/nature11240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050353717", 
          "https://doi.org/10.1038/nrm2330"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-11", 
    "datePublishedReg": "2013-11-01", 
    "description": "It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells. ", 
    "genre": "non_research_article", 
    "id": "sg:pub.10.1038/cr.2013.115", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1107753", 
        "issn": [
          "1001-0602", 
          "1748-7838"
        ], 
        "name": "Cell Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "23"
      }
    ], 
    "name": "Mechanisms of apoptotic phosphatidylserine exposure", 
    "pagination": "1247", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b1d6281cc7a49f86c7fcada8dbbdd4ad338430df94da678a790b2d06cdf3bb59"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23979019"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9425763"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/cr.2013.115"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037332180"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/cr.2013.115", 
      "https://app.dimensions.ai/details/publication/pub.1037332180"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000434.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/cr2013115"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/cr.2013.115'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/cr.2013.115'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/cr.2013.115'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/cr.2013.115'


 

This table displays all metadata directly associated to this object as RDF triples.

137 TRIPLES      21 PREDICATES      43 URIs      27 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/cr.2013.115 schema:about N38f12722950347cc874c3a9247d91458
2 N6a3c1ac47bed4398a8d677c06de510e0
3 Na0ae4803c3cc4c44a65ed26cc3c36d9c
4 Na55c0065ca2541e0bc4c82377bd52232
5 Ncf96ec4e6c5f45879fffb35863de284e
6 Ne2212cf95d5d45c5b85f0d7fa699119a
7 anzsrc-for:06
8 anzsrc-for:0601
9 schema:author N0138bc5d7deb47029467902f1e75caf2
10 schema:citation sg:pub.10.1038/17135
11 sg:pub.10.1038/nature09583
12 sg:pub.10.1038/nature11240
13 sg:pub.10.1038/ncb1574
14 sg:pub.10.1038/nrm2330
15 https://doi.org/10.1016/s1097-2765(00)80437-2
16 https://doi.org/10.1126/science.1236758
17 https://doi.org/10.1146/annurev.biophys.093008.131234
18 schema:datePublished 2013-11
19 schema:datePublishedReg 2013-11-01
20 schema:description It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells.
21 schema:genre non_research_article
22 schema:inLanguage en
23 schema:isAccessibleForFree true
24 schema:isPartOf N0e9f3e1f2f7f4b659949588aabcaa219
25 Nd313278a362a465ebeae64be47da0691
26 sg:journal.1107753
27 schema:name Mechanisms of apoptotic phosphatidylserine exposure
28 schema:pagination 1247
29 schema:productId N33ddbe15d36b49ecab40cfb288900b34
30 N559002a7932c48b5b0da8d093f1bd6c9
31 N595c66ab271c472aa12026644774e7fb
32 Nb91bddaa146243688a7cace430b7e6b8
33 Ncfbc12c0b41f4ce88be4d37186fd8b21
34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037332180
35 https://doi.org/10.1038/cr.2013.115
36 schema:sdDatePublished 2019-04-10T17:20
37 schema:sdLicense https://scigraph.springernature.com/explorer/license/
38 schema:sdPublisher Nb988abada96549d68e6244c5782ba72d
39 schema:url https://www.nature.com/articles/cr2013115
40 sgo:license sg:explorer/license/
41 sgo:sdDataset articles
42 rdf:type schema:ScholarlyArticle
43 N0138bc5d7deb47029467902f1e75caf2 rdf:first sg:person.0765732226.52
44 rdf:rest N3915a4af37664ed2a10fd5d0fb41a628
45 N0e9f3e1f2f7f4b659949588aabcaa219 schema:issueNumber 11
46 rdf:type schema:PublicationIssue
47 N33ddbe15d36b49ecab40cfb288900b34 schema:name readcube_id
48 schema:value b1d6281cc7a49f86c7fcada8dbbdd4ad338430df94da678a790b2d06cdf3bb59
49 rdf:type schema:PropertyValue
50 N38f12722950347cc874c3a9247d91458 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
51 schema:name Cell Membrane
52 rdf:type schema:DefinedTerm
53 N3915a4af37664ed2a10fd5d0fb41a628 rdf:first sg:person.0610375740.57
54 rdf:rest rdf:nil
55 N559002a7932c48b5b0da8d093f1bd6c9 schema:name nlm_unique_id
56 schema:value 9425763
57 rdf:type schema:PropertyValue
58 N595c66ab271c472aa12026644774e7fb schema:name doi
59 schema:value 10.1038/cr.2013.115
60 rdf:type schema:PropertyValue
61 N6a3c1ac47bed4398a8d677c06de510e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Humans
63 rdf:type schema:DefinedTerm
64 Na0ae4803c3cc4c44a65ed26cc3c36d9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Phospholipids
66 rdf:type schema:DefinedTerm
67 Na55c0065ca2541e0bc4c82377bd52232 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Calcium
69 rdf:type schema:DefinedTerm
70 Nb91bddaa146243688a7cace430b7e6b8 schema:name dimensions_id
71 schema:value pub.1037332180
72 rdf:type schema:PropertyValue
73 Nb988abada96549d68e6244c5782ba72d schema:name Springer Nature - SN SciGraph project
74 rdf:type schema:Organization
75 Ncf96ec4e6c5f45879fffb35863de284e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Phospholipid Transfer Proteins
77 rdf:type schema:DefinedTerm
78 Ncfbc12c0b41f4ce88be4d37186fd8b21 schema:name pubmed_id
79 schema:value 23979019
80 rdf:type schema:PropertyValue
81 Nd313278a362a465ebeae64be47da0691 schema:volumeNumber 23
82 rdf:type schema:PublicationVolume
83 Ne2212cf95d5d45c5b85f0d7fa699119a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Animals
85 rdf:type schema:DefinedTerm
86 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
87 schema:name Biological Sciences
88 rdf:type schema:DefinedTerm
89 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
90 schema:name Biochemistry and Cell Biology
91 rdf:type schema:DefinedTerm
92 sg:journal.1107753 schema:issn 1001-0602
93 1748-7838
94 schema:name Cell Research
95 rdf:type schema:Periodical
96 sg:person.0610375740.57 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
97 schema:familyName Kroemer
98 schema:givenName Guido
99 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610375740.57
100 rdf:type schema:Person
101 sg:person.0765732226.52 schema:affiliation https://www.grid.ac/institutes/grid.10992.33
102 schema:familyName Mariño
103 schema:givenName Guillermo
104 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765732226.52
105 rdf:type schema:Person
106 sg:pub.10.1038/17135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031480889
107 https://doi.org/10.1038/17135
108 rdf:type schema:CreativeWork
109 sg:pub.10.1038/nature09583 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027963928
110 https://doi.org/10.1038/nature09583
111 rdf:type schema:CreativeWork
112 sg:pub.10.1038/nature11240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047562121
113 https://doi.org/10.1038/nature11240
114 rdf:type schema:CreativeWork
115 sg:pub.10.1038/ncb1574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032804444
116 https://doi.org/10.1038/ncb1574
117 rdf:type schema:CreativeWork
118 sg:pub.10.1038/nrm2330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050353717
119 https://doi.org/10.1038/nrm2330
120 rdf:type schema:CreativeWork
121 https://doi.org/10.1016/s1097-2765(00)80437-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009229085
122 rdf:type schema:CreativeWork
123 https://doi.org/10.1126/science.1236758 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019935444
124 rdf:type schema:CreativeWork
125 https://doi.org/10.1146/annurev.biophys.093008.131234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026305745
126 rdf:type schema:CreativeWork
127 https://www.grid.ac/institutes/grid.10992.33 schema:alternateName Paris Descartes University
128 schema:name INSERM, U848, F-94805 Villejuif, France
129 Université Paris Descartes/Paris V, Sorbonne Paris Cité, 75006 Paris, France
130 rdf:type schema:Organization
131 https://www.grid.ac/institutes/grid.14925.3b schema:alternateName Institut Gustave Roussy
132 schema:name Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, F-75006 Paris, France
133 INSERM, U848, F-94805 Villejuif, France
134 Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, F-94805 Villejuif, France
135 Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, F-75015 Paris, France
136 Université Paris Descartes/Paris V, Sorbonne Paris Cité, 75006 Paris, France
137 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...