Mechanisms of apoptotic phosphatidylserine exposure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-11

AUTHORS

Guillermo Mariño, Guido Kroemer

ABSTRACT

It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells. More... »

PAGES

1247

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/cr.2013.115

DOI

http://dx.doi.org/10.1038/cr.2013.115

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037332180

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23979019


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