Clinical guide to fertility preservation in hematopoietic cell transplant recipients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-04

AUTHORS

S Joshi, B N Savani, E J Chow, M H Gilleece, J Halter, D A Jacobsohn, J Pidala, G P Quinn, J-Y Cahn, A A Jakubowski, N R Kamani, H M Lazarus, J D Rizzo, H C Schouten, G Socie, P Stratton, M L Sorror, A B Warwick, J R Wingard, A W Loren, N S Majhail

ABSTRACT

With broadening indications, more options for hematopoietic cell transplantation (HCT) and improvement in survival, the number of long-term HCT survivors is expected to increase steadily. Infertility is a frequent problem that long-term HCT survivors and their partners face and it can negatively impact on the quality of life. The most optimal time to address fertility issues is before the onset of therapy for the underlying disease; however, fertility preservation should also be addressed before HCT in all children and patients of reproductive age, with referral to a reproductive specialist for patients interested in fertility preservation. In vitro fertilization (IVF) and embryo cryopreservation, oocyte cryopreservation and ovarian tissue banking are acceptable methods for fertility preservation in adult women/pubertal females. Sperm banking is the preferred method for adult men/pubertal males. Frequent barriers to fertility preservation in HCT recipients may include the perception of lack of time to preserve fertility given an urgency to move ahead with transplant, lack of patient-physician discussion because of several factors (for example, time constraints, lack of knowledge), inadequate access to reproductive specialists, and costs and lack of insurance coverage for fertility preservation. There is a need to raise awareness in the medical community about fertility preservation in HCT recipients. More... »

PAGES

477

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bmt.2013.211

DOI

http://dx.doi.org/10.1038/bmt.2013.211

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045440735

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24419521


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613 rdf:type schema:Organization
614 https://www.grid.ac/institutes/grid.443984.6 schema:alternateName St James's University Hospital
615 schema:name Department of Haematology, St. James's University Hospital, Leeds, UK.
616 rdf:type schema:Organization
617 https://www.grid.ac/institutes/grid.468198.a schema:alternateName Moffitt Cancer Center
618 schema:name Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL, USA.
619 Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
620 rdf:type schema:Organization
621 https://www.grid.ac/institutes/grid.51462.34 schema:alternateName Memorial Sloan Kettering Cancer Center
622 schema:name Division of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
623 rdf:type schema:Organization
 




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