Stem cell collection in patients with multiple myeloma: impact of induction therapy and mobilization regimen View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-05-03

AUTHORS

A Nazha, R Cook, D T Vogl, P A Mangan, M Gardler, K Hummel, K Cunningham, S M Luger, D L Porter, S Schuster, U O'Doherty, D Siegel, E A Stadtmauer

ABSTRACT

Lenalidomide is an active treatment for multiple myeloma (MM) and is increasingly used as part of the initial treatment of this disease. Recent reports have suggested decreases in the number of CD34+ cells collected and increases in the failure rate among patients whose initial therapy contained lenalidomide when mobilized with G-CSF alone. A retrospective data analysis of 364 patients with MM who underwent stem cell mobilization and attempted harvest at the Hospital of the University of Pennsylvania between January 2002 and December 2007 was performed. Forty-three of the patients received lenalidomide in their induction regimen, and were mobilized with either CY and G-CSF or G-CSF alone. The number of apheresis cycles and the failure rate were lower, whereas the mean number of collected stem cells was higher in patients who were mobilized with CY and G-CSF in comparison with G-CSF alone. This suggests that lenalidomide does not prevent the harvest of adequate numbers of CD34 cells for autologous stem cell transplant, but mobilization with G-CSF and CY may be required to obtain adequate numbers of stem cells. Finally, in our study, the number of lenalidomide cycles did not correlate with stem cell yield. More... »

PAGES

59-63

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bmt.2010.63

DOI

http://dx.doi.org/10.1038/bmt.2010.63

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041512897

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20421869


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD34", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Component Removal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cyclophosphamide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Granulocyte Colony-Stimulating Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Mobilization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lenalidomide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Medical Records", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multiple Myeloma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peripheral Blood Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Remission Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thalidomide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation Conditioning", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Autologous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nazha", 
        "givenName": "A", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cook", 
        "givenName": "R", 
        "id": "sg:person.01175252676.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175252676.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vogl", 
        "givenName": "D T", 
        "id": "sg:person.01154427341.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154427341.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mangan", 
        "givenName": "P A", 
        "id": "sg:person.01342007330.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342007330.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gardler", 
        "givenName": "M", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hummel", 
        "givenName": "K", 
        "id": "sg:person.0726540325.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726540325.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cunningham", 
        "givenName": "K", 
        "id": "sg:person.0634210376.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634210376.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Luger", 
        "givenName": "S M", 
        "id": "sg:person.012415664717.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012415664717.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Porter", 
        "givenName": "D L", 
        "id": "sg:person.0707416147.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707416147.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schuster", 
        "givenName": "S", 
        "id": "sg:person.011060364477.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011060364477.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "O'Doherty", 
        "givenName": "U", 
        "id": "sg:person.0626647504.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626647504.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siegel", 
        "givenName": "D", 
        "id": "sg:person.014314214442.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014314214442.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.412701.1", 
          "name": [
            "Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stadtmauer", 
        "givenName": "E A", 
        "id": "sg:person.01044042041.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044042041.97"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.leu.2404801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011029060", 
          "https://doi.org/10.1038/sj.leu.2404801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2405035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027346890", 
          "https://doi.org/10.1038/sj.leu.2405035"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-05-03", 
    "datePublishedReg": "2010-05-03", 
    "description": "Lenalidomide is an active treatment for multiple myeloma (MM) and is increasingly used as part of the initial treatment of this disease. Recent reports have suggested decreases in the number of CD34+ cells collected and increases in the failure rate among patients whose initial therapy contained lenalidomide when mobilized with G-CSF alone. A retrospective data analysis of 364 patients with MM who underwent stem cell mobilization and attempted harvest at the Hospital of the University of Pennsylvania between January 2002 and December 2007 was performed. Forty-three of the patients received lenalidomide in their induction regimen, and were mobilized with either CY and G-CSF or G-CSF alone. The number of apheresis cycles and the failure rate were lower, whereas the mean number of collected stem cells was higher in patients who were mobilized with CY and G-CSF in comparison with G-CSF alone. This suggests that lenalidomide does not prevent the harvest of adequate numbers of CD34 cells for autologous stem cell transplant, but mobilization with G-CSF and CY may be required to obtain adequate numbers of stem cells. Finally, in our study, the number of lenalidomide cycles did not correlate with stem cell yield.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/bmt.2010.63", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1096890", 
        "issn": [
          "0268-3369", 
          "1476-5365"
        ], 
        "name": "Bone Marrow Transplantation", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "46"
      }
    ], 
    "keywords": [
      "multiple myeloma", 
      "autologous stem cell transplant", 
      "collected stem cells", 
      "stem cell transplant", 
      "number of CD34", 
      "stem cell mobilization", 
      "retrospective data analysis", 
      "stem cell yield", 
      "lenalidomide cycles", 
      "initial therapy", 
      "induction therapy", 
      "induction regimen", 
      "stem cells", 
      "initial treatment", 
      "mobilization regimen", 
      "active treatment", 
      "failure rate", 
      "cell transplant", 
      "adequate number", 
      "cell mobilization", 
      "apheresis cycles", 
      "patients", 
      "cell collection", 
      "lenalidomide", 
      "CD34 cells", 
      "CSF", 
      "mean number", 
      "regimen", 
      "myeloma", 
      "University of Pennsylvania", 
      "therapy", 
      "recent reports", 
      "treatment", 
      "cells", 
      "transplant", 
      "hospital", 
      "cell yield", 
      "mobilization", 
      "disease", 
      "CD34", 
      "report", 
      "rate", 
      "number", 
      "Cys", 
      "decrease", 
      "data analysis", 
      "study", 
      "increase", 
      "cycle", 
      "Pennsylvania", 
      "impact", 
      "comparison", 
      "analysis", 
      "collection", 
      "part", 
      "University", 
      "harvest", 
      "yield"
    ], 
    "name": "Stem cell collection in patients with multiple myeloma: impact of induction therapy and mobilization regimen", 
    "pagination": "59-63", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1041512897"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/bmt.2010.63"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "20421869"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/bmt.2010.63", 
      "https://app.dimensions.ai/details/publication/pub.1041512897"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_514.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/bmt.2010.63"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.63'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.63'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.63'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.63'


 

This table displays all metadata directly associated to this object as RDF triples.

282 TRIPLES      22 PREDICATES      104 URIs      94 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/bmt.2010.63 schema:about N0240a0365a8a4db6bb744dc3043c102c
2 N0f05949e1bae4bf3804a46cd87f01ab0
3 N12fb3b4c2b344bdca83bd12a4b1b8436
4 N2e5b29e306e74466824e5b4a1e343487
5 N2f7d8547a6cd403aae7423bde2e58641
6 N3201fbed9b624c72a3aac0d4de7856c4
7 N64a22c80d62d4dbfa7267764cade6e29
8 N6e88aed9de094cb9aa6f1ef3724a056c
9 N6fee5b7ad7794bb4b7f928fdc8839534
10 N79806f6a78f94414bdff0b025999ed88
11 N8f26259a609248d6b4f7dd4c5c1a3c80
12 Nbd1e19ede3924671a2aefd0a5c621582
13 Nbe9a0cb620d5459cb99c84ead978d70f
14 Nc036349b89ce4b14969f6374dfa552d7
15 Nd0a26f1660d5478f96b1e81af6ba4ed6
16 Nd1ba3c83443e48eba81f5e8cd15ad6e7
17 Ne6948508b8044f41b2f96b1c0593ee73
18 Nfa55eef122f54e28ae7092f0da7b0c28
19 anzsrc-for:11
20 anzsrc-for:1102
21 schema:author N808c730abfed48bdb84934b7b0ab5af5
22 schema:citation sg:pub.10.1038/sj.leu.2404801
23 sg:pub.10.1038/sj.leu.2405035
24 schema:datePublished 2010-05-03
25 schema:datePublishedReg 2010-05-03
26 schema:description Lenalidomide is an active treatment for multiple myeloma (MM) and is increasingly used as part of the initial treatment of this disease. Recent reports have suggested decreases in the number of CD34+ cells collected and increases in the failure rate among patients whose initial therapy contained lenalidomide when mobilized with G-CSF alone. A retrospective data analysis of 364 patients with MM who underwent stem cell mobilization and attempted harvest at the Hospital of the University of Pennsylvania between January 2002 and December 2007 was performed. Forty-three of the patients received lenalidomide in their induction regimen, and were mobilized with either CY and G-CSF or G-CSF alone. The number of apheresis cycles and the failure rate were lower, whereas the mean number of collected stem cells was higher in patients who were mobilized with CY and G-CSF in comparison with G-CSF alone. This suggests that lenalidomide does not prevent the harvest of adequate numbers of CD34 cells for autologous stem cell transplant, but mobilization with G-CSF and CY may be required to obtain adequate numbers of stem cells. Finally, in our study, the number of lenalidomide cycles did not correlate with stem cell yield.
27 schema:genre article
28 schema:inLanguage en
29 schema:isAccessibleForFree true
30 schema:isPartOf N76096885256e4c74bbb184892d7c53af
31 N877e4cf74eed4e058646b2e7c70f43db
32 sg:journal.1096890
33 schema:keywords CD34
34 CD34 cells
35 CSF
36 Cys
37 Pennsylvania
38 University
39 University of Pennsylvania
40 active treatment
41 adequate number
42 analysis
43 apheresis cycles
44 autologous stem cell transplant
45 cell collection
46 cell mobilization
47 cell transplant
48 cell yield
49 cells
50 collected stem cells
51 collection
52 comparison
53 cycle
54 data analysis
55 decrease
56 disease
57 failure rate
58 harvest
59 hospital
60 impact
61 increase
62 induction regimen
63 induction therapy
64 initial therapy
65 initial treatment
66 lenalidomide
67 lenalidomide cycles
68 mean number
69 mobilization
70 mobilization regimen
71 multiple myeloma
72 myeloma
73 number
74 number of CD34
75 part
76 patients
77 rate
78 recent reports
79 regimen
80 report
81 retrospective data analysis
82 stem cell mobilization
83 stem cell transplant
84 stem cell yield
85 stem cells
86 study
87 therapy
88 transplant
89 treatment
90 yield
91 schema:name Stem cell collection in patients with multiple myeloma: impact of induction therapy and mobilization regimen
92 schema:pagination 59-63
93 schema:productId N1c158359ab9d47e09da8fd61b0cb434f
94 N7f03a42bffee43efbd66ca1ab4c45974
95 Nfee5c6e58c204c4aa8623a7028cfda80
96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041512897
97 https://doi.org/10.1038/bmt.2010.63
98 schema:sdDatePublished 2021-12-01T19:23
99 schema:sdLicense https://scigraph.springernature.com/explorer/license/
100 schema:sdPublisher Naf4783daa7e64d31a592feec30923f9a
101 schema:url https://doi.org/10.1038/bmt.2010.63
102 sgo:license sg:explorer/license/
103 sgo:sdDataset articles
104 rdf:type schema:ScholarlyArticle
105 N0240a0365a8a4db6bb744dc3043c102c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Medical Records
107 rdf:type schema:DefinedTerm
108 N0f05949e1bae4bf3804a46cd87f01ab0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Blood Component Removal
110 rdf:type schema:DefinedTerm
111 N11f138cdb81d4c918def72db3319fe69 rdf:first sg:person.0707416147.15
112 rdf:rest Na6ddcb1bfccc4f8582f148be6d8dc39a
113 N12fb3b4c2b344bdca83bd12a4b1b8436 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Humans
115 rdf:type schema:DefinedTerm
116 N1c158359ab9d47e09da8fd61b0cb434f schema:name dimensions_id
117 schema:value pub.1041512897
118 rdf:type schema:PropertyValue
119 N2e5b29e306e74466824e5b4a1e343487 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Peripheral Blood Stem Cell Transplantation
121 rdf:type schema:DefinedTerm
122 N2f7d8547a6cd403aae7423bde2e58641 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Antigens, CD34
124 rdf:type schema:DefinedTerm
125 N3201fbed9b624c72a3aac0d4de7856c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Multiple Myeloma
127 rdf:type schema:DefinedTerm
128 N32fbde7349424431abaac2833a3b7648 rdf:first N663dfcd9999040f889dc305a82abd685
129 rdf:rest N72b48f29d2c945d4877ae87aef80237d
130 N64a22c80d62d4dbfa7267764cade6e29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Retrospective Studies
132 rdf:type schema:DefinedTerm
133 N663dfcd9999040f889dc305a82abd685 schema:affiliation grid-institutes:grid.412701.1
134 schema:familyName Gardler
135 schema:givenName M
136 rdf:type schema:Person
137 N6a0bc3ef01d1418f8ea73c9baa74b409 rdf:first sg:person.012415664717.68
138 rdf:rest N11f138cdb81d4c918def72db3319fe69
139 N6d142f5efdc84b679a3f9f0280a5cf02 rdf:first sg:person.01342007330.30
140 rdf:rest N32fbde7349424431abaac2833a3b7648
141 N6e88aed9de094cb9aa6f1ef3724a056c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Lenalidomide
143 rdf:type schema:DefinedTerm
144 N6fee5b7ad7794bb4b7f928fdc8839534 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Remission Induction
146 rdf:type schema:DefinedTerm
147 N72b48f29d2c945d4877ae87aef80237d rdf:first sg:person.0726540325.99
148 rdf:rest N822c0401c9804075bccb82616c1eeb07
149 N7322fe218526491a836c3773d67d7f77 schema:affiliation grid-institutes:grid.412701.1
150 schema:familyName Nazha
151 schema:givenName A
152 rdf:type schema:Person
153 N7588aa9f44a548d4bd40eafdee4daf1e rdf:first sg:person.01154427341.76
154 rdf:rest N6d142f5efdc84b679a3f9f0280a5cf02
155 N76096885256e4c74bbb184892d7c53af schema:volumeNumber 46
156 rdf:type schema:PublicationVolume
157 N79806f6a78f94414bdff0b025999ed88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Treatment Outcome
159 rdf:type schema:DefinedTerm
160 N7f03a42bffee43efbd66ca1ab4c45974 schema:name doi
161 schema:value 10.1038/bmt.2010.63
162 rdf:type schema:PropertyValue
163 N808c730abfed48bdb84934b7b0ab5af5 rdf:first N7322fe218526491a836c3773d67d7f77
164 rdf:rest Na3cf3f0137d14873af245e79c325d958
165 N822c0401c9804075bccb82616c1eeb07 rdf:first sg:person.0634210376.05
166 rdf:rest N6a0bc3ef01d1418f8ea73c9baa74b409
167 N877e4cf74eed4e058646b2e7c70f43db schema:issueNumber 1
168 rdf:type schema:PublicationIssue
169 N8f26259a609248d6b4f7dd4c5c1a3c80 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Thalidomide
171 rdf:type schema:DefinedTerm
172 N96af3f0adeb147d2a67b2b23d995558d rdf:first sg:person.01044042041.97
173 rdf:rest rdf:nil
174 Na3cf3f0137d14873af245e79c325d958 rdf:first sg:person.01175252676.87
175 rdf:rest N7588aa9f44a548d4bd40eafdee4daf1e
176 Na6ddcb1bfccc4f8582f148be6d8dc39a rdf:first sg:person.011060364477.44
177 rdf:rest Nac4f8e18f17344bd937afc107a741731
178 Nac4f8e18f17344bd937afc107a741731 rdf:first sg:person.0626647504.50
179 rdf:rest Nce881913ea874233b7284f8f01f858dd
180 Naf4783daa7e64d31a592feec30923f9a schema:name Springer Nature - SN SciGraph project
181 rdf:type schema:Organization
182 Nbd1e19ede3924671a2aefd0a5c621582 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Granulocyte Colony-Stimulating Factor
184 rdf:type schema:DefinedTerm
185 Nbe9a0cb620d5459cb99c84ead978d70f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Cyclophosphamide
187 rdf:type schema:DefinedTerm
188 Nc036349b89ce4b14969f6374dfa552d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Antineoplastic Agents
190 rdf:type schema:DefinedTerm
191 Nce881913ea874233b7284f8f01f858dd rdf:first sg:person.014314214442.02
192 rdf:rest N96af3f0adeb147d2a67b2b23d995558d
193 Nd0a26f1660d5478f96b1e81af6ba4ed6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Drug Therapy, Combination
195 rdf:type schema:DefinedTerm
196 Nd1ba3c83443e48eba81f5e8cd15ad6e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Transplantation Conditioning
198 rdf:type schema:DefinedTerm
199 Ne6948508b8044f41b2f96b1c0593ee73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Transplantation, Autologous
201 rdf:type schema:DefinedTerm
202 Nfa55eef122f54e28ae7092f0da7b0c28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Hematopoietic Stem Cell Mobilization
204 rdf:type schema:DefinedTerm
205 Nfee5c6e58c204c4aa8623a7028cfda80 schema:name pubmed_id
206 schema:value 20421869
207 rdf:type schema:PropertyValue
208 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
209 schema:name Medical and Health Sciences
210 rdf:type schema:DefinedTerm
211 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
212 schema:name Cardiorespiratory Medicine and Haematology
213 rdf:type schema:DefinedTerm
214 sg:journal.1096890 schema:issn 0268-3369
215 1476-5365
216 schema:name Bone Marrow Transplantation
217 schema:publisher Springer Nature
218 rdf:type schema:Periodical
219 sg:person.01044042041.97 schema:affiliation grid-institutes:grid.412701.1
220 schema:familyName Stadtmauer
221 schema:givenName E A
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044042041.97
223 rdf:type schema:Person
224 sg:person.011060364477.44 schema:affiliation grid-institutes:grid.412701.1
225 schema:familyName Schuster
226 schema:givenName S
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011060364477.44
228 rdf:type schema:Person
229 sg:person.01154427341.76 schema:affiliation grid-institutes:grid.412701.1
230 schema:familyName Vogl
231 schema:givenName D T
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154427341.76
233 rdf:type schema:Person
234 sg:person.01175252676.87 schema:affiliation grid-institutes:grid.412701.1
235 schema:familyName Cook
236 schema:givenName R
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175252676.87
238 rdf:type schema:Person
239 sg:person.012415664717.68 schema:affiliation grid-institutes:grid.412701.1
240 schema:familyName Luger
241 schema:givenName S M
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012415664717.68
243 rdf:type schema:Person
244 sg:person.01342007330.30 schema:affiliation grid-institutes:grid.412701.1
245 schema:familyName Mangan
246 schema:givenName P A
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342007330.30
248 rdf:type schema:Person
249 sg:person.014314214442.02 schema:affiliation grid-institutes:grid.412701.1
250 schema:familyName Siegel
251 schema:givenName D
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014314214442.02
253 rdf:type schema:Person
254 sg:person.0626647504.50 schema:affiliation grid-institutes:grid.412701.1
255 schema:familyName O'Doherty
256 schema:givenName U
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626647504.50
258 rdf:type schema:Person
259 sg:person.0634210376.05 schema:affiliation grid-institutes:grid.412701.1
260 schema:familyName Cunningham
261 schema:givenName K
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634210376.05
263 rdf:type schema:Person
264 sg:person.0707416147.15 schema:affiliation grid-institutes:grid.412701.1
265 schema:familyName Porter
266 schema:givenName D L
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707416147.15
268 rdf:type schema:Person
269 sg:person.0726540325.99 schema:affiliation grid-institutes:grid.412701.1
270 schema:familyName Hummel
271 schema:givenName K
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726540325.99
273 rdf:type schema:Person
274 sg:pub.10.1038/sj.leu.2404801 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011029060
275 https://doi.org/10.1038/sj.leu.2404801
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/sj.leu.2405035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027346890
278 https://doi.org/10.1038/sj.leu.2405035
279 rdf:type schema:CreativeWork
280 grid-institutes:grid.412701.1 schema:alternateName Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA
281 schema:name Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA
282 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...