Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-11

AUTHORS

K Kataoka, Y Nannya, H Iwata, S Seo, K Kumano, T Takahashi, R Nagai, M Kurokawa

ABSTRACT

Fluid retention is characteristic of veno-occlusive disease (VOD). We hypothesized that plasma brain natriuretic peptide (BNP), a neurohormone secreted in response to volume expansion, may be associated with VOD after hematopoietic stem cell transplantation (HSCT). BNP was measured before and weekly after HSCT in 46 recipients. Sixteen patients developed VOD. BNP concentrations were similar before and on day 0 in patients with and without VOD, but were significantly higher on day 7 and later in those with VOD. Patients with VOD had significantly higher peak BNP concentrations before engraftment than those without VOD (median, 634.4 versus 80.9 pg ml⁻¹; P=0.01). Multivariate analysis showed that VOD was independently associated with BNP elevation (odds ratio, 50.1; 95% CI: 5.2-478.4; P<0.01). Landmark analysis at day 7 showed that patients with peak BNP concentration of ≥ 180 pg ml⁻¹ had significantly worse 100-day survival than patients with peak BNP <180 pg ml⁻¹ (54 versus 91%; P<0.01). In multivariate analysis, BNP elevation before day 7 significantly predicted 100-day survival (hazard ratio 5.3; 95% CI: 1.1-24.3; P=0.03). These findings suggest that plasma BNP may serve as a diagnostic and prognostic marker of VOD. More... »

PAGES

1631

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bmt.2010.26

DOI

http://dx.doi.org/10.1038/bmt.2010.26

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039693238

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20173786


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatic Veno-Occlusive Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Natriuretic Peptide, Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Japan Society for the Promotion of Science", 
          "id": "https://www.grid.ac/institutes/grid.54432.34", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan", 
            "The Japan Society for the Promotion of Science, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kataoka", 
        "givenName": "K", 
        "id": "sg:person.01351121346.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351121346.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nannya", 
        "givenName": "Y", 
        "id": "sg:person.0741743646.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741743646.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwata", 
        "givenName": "H", 
        "id": "sg:person.01117156143.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117156143.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seo", 
        "givenName": "S", 
        "id": "sg:person.0713436676.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713436676.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412708.8", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan", 
            "Department of Cell Therapy and Transplantation Medicine, University of Tokyo Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumano", 
        "givenName": "K", 
        "id": "sg:person.0650522350.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650522350.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takahashi", 
        "givenName": "T", 
        "id": "sg:person.012171335164.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012171335164.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagai", 
        "givenName": "R", 
        "id": "sg:person.0772176333.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772176333.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412708.8", 
          "name": [
            "Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan", 
            "Department of Cell Therapy and Transplantation Medicine, University of Tokyo Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kurokawa", 
        "givenName": "M", 
        "id": "sg:person.01124305446.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124305446.95"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00002-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001041233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00002-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001041233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002770100331", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003150617", 
          "https://doi.org/10.1007/s002770100331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2002-04-1216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003577261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.472050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005176581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00062752-200311000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005876894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00062752-200311000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005876894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4065/78.5.589", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006383624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa031681", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006658635"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.101.6.1644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006971593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1702507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008368148", 
          "https://doi.org/10.1038/sj.bmt.1702507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1702507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008368148", 
          "https://doi.org/10.1038/sj.bmt.1702507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.677625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008479934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa020233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010471027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa011053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011170971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.2008.07165.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011537997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000114827.93410.d8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019228063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000114827.93410.d8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019228063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yjmcc.2004.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020878767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2169/internalmedicine.46.6188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023530366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.129.5.1349", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024620026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2005.00078.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026165994", 
          "https://doi.org/10.1111/j.1523-1755.2005.00078.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3317/jraas.2000.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032744835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3317/jraas.2000.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032744835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.52.10.1511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039235567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000259469.24364.31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042563268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000259469.24364.31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042563268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1026195332025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049488417", 
          "https://doi.org/10.1023/a:1026195332025"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/criticalvalues/2.2.30", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049588998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(03)13976-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051340263"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10245330600774991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058358131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/28.10.1519", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059487983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-118-4-199302150-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073697190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082422699", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1993.11.9.1729", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082771859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082878635", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.1997.273.6.h2678", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083199751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083296900", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-11", 
    "datePublishedReg": "2010-11-01", 
    "description": "Fluid retention is characteristic of veno-occlusive disease (VOD). We hypothesized that plasma brain natriuretic peptide (BNP), a neurohormone secreted in response to volume expansion, may be associated with VOD after hematopoietic stem cell transplantation (HSCT). BNP was measured before and weekly after HSCT in 46 recipients. Sixteen patients developed VOD. BNP concentrations were similar before and on day 0 in patients with and without VOD, but were significantly higher on day 7 and later in those with VOD. Patients with VOD had significantly higher peak BNP concentrations before engraftment than those without VOD (median, 634.4 versus 80.9 \u2009pg\u2009 ml\u207b\u00b9; P=0.01). Multivariate analysis showed that VOD was independently associated with BNP elevation (odds ratio, 50.1; 95% CI: 5.2-478.4; P<0.01). Landmark analysis at day 7 showed that patients with peak BNP concentration of \u2265 180 \u2009pg\u2009 ml\u207b\u00b9 had significantly worse 100-day survival than patients with peak BNP <180 \u2009pg\u2009 ml\u207b\u00b9 (54 versus 91%; P<0.01). In multivariate analysis, BNP elevation before day 7 significantly predicted 100-day survival (hazard ratio 5.3; 95% CI: 1.1-24.3; P=0.03). These findings suggest that plasma BNP may serve as a diagnostic and prognostic marker of VOD.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/bmt.2010.26", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1096890", 
        "issn": [
          "0268-3369", 
          "1476-5365"
        ], 
        "name": "Bone Marrow Transplantation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "45"
      }
    ], 
    "name": "Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation", 
    "pagination": "1631", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "bd14b23c6ac127593fa393ba5bbe3ffd0ccfcb5f36e2859efcd550026adafc77"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "20173786"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8702459"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/bmt.2010.26"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039693238"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/bmt.2010.26", 
      "https://app.dimensions.ai/details/publication/pub.1039693238"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89826_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/bmt201026"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.26'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.26'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.26'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/bmt.2010.26'


 

This table displays all metadata directly associated to this object as RDF triples.

280 TRIPLES      21 PREDICATES      75 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/bmt.2010.26 schema:about N1a43031eadd141b388fc18d26360916d
2 N1ca1a3a36df4486f93c7a9f71840dd18
3 N2e91e091d77e4f5987761c6ad9ee4c7d
4 N531adb9695364f9bad5c470e061883c8
5 N5967fd82be6a471586aa8373d04e1ecc
6 N69fc9ee2d7b24c84b78b0f68bdaa6854
7 N6a50a22c9f2e4fc4ae2990a4e51ec40e
8 N7fb007275b7a4789bd99671dbb864932
9 N9417c66695314051964a2d696a465b48
10 Na1224e0044964ce09ab81c6abc52c64a
11 Nb418927af3144560987170b66ff94527
12 Ncc5b10591d5c42fd87346a616ef19bb0
13 Ne19d3a1552b0406fbc04bbb79960f62e
14 Nee6ca5bc6f8f495faef43953d128290a
15 anzsrc-for:11
16 anzsrc-for:1109
17 schema:author N28f49eb405884de3b25e4db1da312006
18 schema:citation sg:pub.10.1007/s002770100331
19 sg:pub.10.1023/a:1026195332025
20 sg:pub.10.1038/sj.bmt.1702507
21 sg:pub.10.1111/j.1523-1755.2005.00078.x
22 https://app.dimensions.ai/details/publication/pub.1082422699
23 https://app.dimensions.ai/details/publication/pub.1082878635
24 https://app.dimensions.ai/details/publication/pub.1083296900
25 https://doi.org/10.1016/j.yjmcc.2004.01.001
26 https://doi.org/10.1016/s0140-6736(03)13976-1
27 https://doi.org/10.1016/s0268-960x(03)00002-x
28 https://doi.org/10.1056/nejmoa011053
29 https://doi.org/10.1056/nejmoa020233
30 https://doi.org/10.1056/nejmoa031681
31 https://doi.org/10.1080/10245330600774991
32 https://doi.org/10.1093/criticalvalues/2.2.30
33 https://doi.org/10.1093/cvr/28.10.1519
34 https://doi.org/10.1097/00062752-200311000-00010
35 https://doi.org/10.1097/01.ccm.0000114827.93410.d8
36 https://doi.org/10.1097/01.ccm.0000259469.24364.31
37 https://doi.org/10.1111/j.1365-2141.2008.07165.x
38 https://doi.org/10.1136/gut.52.10.1511
39 https://doi.org/10.1152/ajpheart.1997.273.6.h2678
40 https://doi.org/10.1161/circulationaha.104.472050
41 https://doi.org/10.1161/circulationaha.106.677625
42 https://doi.org/10.1182/blood-2002-04-1216
43 https://doi.org/10.1200/jco.1993.11.9.1729
44 https://doi.org/10.1378/chest.101.6.1644
45 https://doi.org/10.1378/chest.129.5.1349
46 https://doi.org/10.2169/internalmedicine.46.6188
47 https://doi.org/10.3317/jraas.2000.059
48 https://doi.org/10.4065/78.5.589
49 https://doi.org/10.7326/0003-4819-118-4-199302150-00003
50 schema:datePublished 2010-11
51 schema:datePublishedReg 2010-11-01
52 schema:description Fluid retention is characteristic of veno-occlusive disease (VOD). We hypothesized that plasma brain natriuretic peptide (BNP), a neurohormone secreted in response to volume expansion, may be associated with VOD after hematopoietic stem cell transplantation (HSCT). BNP was measured before and weekly after HSCT in 46 recipients. Sixteen patients developed VOD. BNP concentrations were similar before and on day 0 in patients with and without VOD, but were significantly higher on day 7 and later in those with VOD. Patients with VOD had significantly higher peak BNP concentrations before engraftment than those without VOD (median, 634.4 versus 80.9  pg  ml⁻¹; P=0.01). Multivariate analysis showed that VOD was independently associated with BNP elevation (odds ratio, 50.1; 95% CI: 5.2-478.4; P<0.01). Landmark analysis at day 7 showed that patients with peak BNP concentration of ≥ 180  pg  ml⁻¹ had significantly worse 100-day survival than patients with peak BNP <180  pg  ml⁻¹ (54 versus 91%; P<0.01). In multivariate analysis, BNP elevation before day 7 significantly predicted 100-day survival (hazard ratio 5.3; 95% CI: 1.1-24.3; P=0.03). These findings suggest that plasma BNP may serve as a diagnostic and prognostic marker of VOD.
53 schema:genre research_article
54 schema:inLanguage en
55 schema:isAccessibleForFree true
56 schema:isPartOf N448b69d34b76478e8a3160ee9b03e3e0
57 N85d0ca777a824ffea5e128ffaed6aacb
58 sg:journal.1096890
59 schema:name Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation
60 schema:pagination 1631
61 schema:productId N0b319aa20cf04089b0ea1a98da5c299d
62 N3bf3b32f097f46a2a2a991a7a142e1bc
63 N7dba0b406749415f9d78050c99115e28
64 N805ec5413d8946dcada6452a496b1859
65 Nae5191b079b54e169e3e8c5d24cda71a
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039693238
67 https://doi.org/10.1038/bmt.2010.26
68 schema:sdDatePublished 2019-04-11T10:04
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher N9a05fd6eb26b4db78c259d828ab68971
71 schema:url https://www.nature.com/articles/bmt201026
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N0416b3c035b7405da78114c2637d8603 rdf:first sg:person.01124305446.95
76 rdf:rest rdf:nil
77 N0b319aa20cf04089b0ea1a98da5c299d schema:name dimensions_id
78 schema:value pub.1039693238
79 rdf:type schema:PropertyValue
80 N16bb3b3a94854541bd0c5734926a965e rdf:first sg:person.0741743646.50
81 rdf:rest N1ff624e389614fc4a896cec19f522429
82 N1a43031eadd141b388fc18d26360916d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Humans
84 rdf:type schema:DefinedTerm
85 N1ca1a3a36df4486f93c7a9f71840dd18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Hematopoietic Stem Cell Transplantation
87 rdf:type schema:DefinedTerm
88 N1ff624e389614fc4a896cec19f522429 rdf:first sg:person.01117156143.59
89 rdf:rest N3f0563bda841446f81a0ca833ab243b1
90 N28f49eb405884de3b25e4db1da312006 rdf:first sg:person.01351121346.32
91 rdf:rest N16bb3b3a94854541bd0c5734926a965e
92 N2e91e091d77e4f5987761c6ad9ee4c7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Middle Aged
94 rdf:type schema:DefinedTerm
95 N3bb033e186694f6b92b5d38b35a425f9 rdf:first sg:person.012171335164.95
96 rdf:rest Nef9e17f35fc04a548f7c8c5bb98ed31e
97 N3bf3b32f097f46a2a2a991a7a142e1bc schema:name doi
98 schema:value 10.1038/bmt.2010.26
99 rdf:type schema:PropertyValue
100 N3f0563bda841446f81a0ca833ab243b1 rdf:first sg:person.0713436676.53
101 rdf:rest Nfab1ff12c67441b0a6c528c3d3c7a15d
102 N448b69d34b76478e8a3160ee9b03e3e0 schema:issueNumber 11
103 rdf:type schema:PublicationIssue
104 N531adb9695364f9bad5c470e061883c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Young Adult
106 rdf:type schema:DefinedTerm
107 N5967fd82be6a471586aa8373d04e1ecc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Natriuretic Peptide, Brain
109 rdf:type schema:DefinedTerm
110 N69fc9ee2d7b24c84b78b0f68bdaa6854 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Adolescent
112 rdf:type schema:DefinedTerm
113 N6a50a22c9f2e4fc4ae2990a4e51ec40e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Survival Rate
115 rdf:type schema:DefinedTerm
116 N7dba0b406749415f9d78050c99115e28 schema:name pubmed_id
117 schema:value 20173786
118 rdf:type schema:PropertyValue
119 N7fb007275b7a4789bd99671dbb864932 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Hepatic Veno-Occlusive Disease
121 rdf:type schema:DefinedTerm
122 N805ec5413d8946dcada6452a496b1859 schema:name nlm_unique_id
123 schema:value 8702459
124 rdf:type schema:PropertyValue
125 N85d0ca777a824ffea5e128ffaed6aacb schema:volumeNumber 45
126 rdf:type schema:PublicationVolume
127 N9417c66695314051964a2d696a465b48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Adult
129 rdf:type schema:DefinedTerm
130 N9a05fd6eb26b4db78c259d828ab68971 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 Na1224e0044964ce09ab81c6abc52c64a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Risk Factors
134 rdf:type schema:DefinedTerm
135 Nae5191b079b54e169e3e8c5d24cda71a schema:name readcube_id
136 schema:value bd14b23c6ac127593fa393ba5bbe3ffd0ccfcb5f36e2859efcd550026adafc77
137 rdf:type schema:PropertyValue
138 Nb418927af3144560987170b66ff94527 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Retrospective Studies
140 rdf:type schema:DefinedTerm
141 Ncc5b10591d5c42fd87346a616ef19bb0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Male
143 rdf:type schema:DefinedTerm
144 Ne19d3a1552b0406fbc04bbb79960f62e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Female
146 rdf:type schema:DefinedTerm
147 Nee6ca5bc6f8f495faef43953d128290a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Aged
149 rdf:type schema:DefinedTerm
150 Nef9e17f35fc04a548f7c8c5bb98ed31e rdf:first sg:person.0772176333.38
151 rdf:rest N0416b3c035b7405da78114c2637d8603
152 Nfab1ff12c67441b0a6c528c3d3c7a15d rdf:first sg:person.0650522350.37
153 rdf:rest N3bb033e186694f6b92b5d38b35a425f9
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
158 schema:name Neurosciences
159 rdf:type schema:DefinedTerm
160 sg:journal.1096890 schema:issn 0268-3369
161 1476-5365
162 schema:name Bone Marrow Transplantation
163 rdf:type schema:Periodical
164 sg:person.01117156143.59 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
165 schema:familyName Iwata
166 schema:givenName H
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117156143.59
168 rdf:type schema:Person
169 sg:person.01124305446.95 schema:affiliation https://www.grid.ac/institutes/grid.412708.8
170 schema:familyName Kurokawa
171 schema:givenName M
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124305446.95
173 rdf:type schema:Person
174 sg:person.012171335164.95 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
175 schema:familyName Takahashi
176 schema:givenName T
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012171335164.95
178 rdf:type schema:Person
179 sg:person.01351121346.32 schema:affiliation https://www.grid.ac/institutes/grid.54432.34
180 schema:familyName Kataoka
181 schema:givenName K
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351121346.32
183 rdf:type schema:Person
184 sg:person.0650522350.37 schema:affiliation https://www.grid.ac/institutes/grid.412708.8
185 schema:familyName Kumano
186 schema:givenName K
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650522350.37
188 rdf:type schema:Person
189 sg:person.0713436676.53 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
190 schema:familyName Seo
191 schema:givenName S
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713436676.53
193 rdf:type schema:Person
194 sg:person.0741743646.50 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
195 schema:familyName Nannya
196 schema:givenName Y
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741743646.50
198 rdf:type schema:Person
199 sg:person.0772176333.38 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
200 schema:familyName Nagai
201 schema:givenName R
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772176333.38
203 rdf:type schema:Person
204 sg:pub.10.1007/s002770100331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003150617
205 https://doi.org/10.1007/s002770100331
206 rdf:type schema:CreativeWork
207 sg:pub.10.1023/a:1026195332025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049488417
208 https://doi.org/10.1023/a:1026195332025
209 rdf:type schema:CreativeWork
210 sg:pub.10.1038/sj.bmt.1702507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008368148
211 https://doi.org/10.1038/sj.bmt.1702507
212 rdf:type schema:CreativeWork
213 sg:pub.10.1111/j.1523-1755.2005.00078.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026165994
214 https://doi.org/10.1111/j.1523-1755.2005.00078.x
215 rdf:type schema:CreativeWork
216 https://app.dimensions.ai/details/publication/pub.1082422699 schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1082878635 schema:CreativeWork
218 https://app.dimensions.ai/details/publication/pub.1083296900 schema:CreativeWork
219 https://doi.org/10.1016/j.yjmcc.2004.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020878767
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/s0140-6736(03)13976-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051340263
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/s0268-960x(03)00002-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001041233
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1056/nejmoa011053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011170971
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1056/nejmoa020233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010471027
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1056/nejmoa031681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006658635
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1080/10245330600774991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058358131
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1093/criticalvalues/2.2.30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049588998
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1093/cvr/28.10.1519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059487983
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1097/00062752-200311000-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005876894
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1097/01.ccm.0000114827.93410.d8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019228063
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1097/01.ccm.0000259469.24364.31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042563268
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1111/j.1365-2141.2008.07165.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011537997
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1136/gut.52.10.1511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039235567
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1152/ajpheart.1997.273.6.h2678 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083199751
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1161/circulationaha.104.472050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005176581
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1161/circulationaha.106.677625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008479934
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1182/blood-2002-04-1216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003577261
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1200/jco.1993.11.9.1729 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082771859
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1378/chest.101.6.1644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006971593
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1378/chest.129.5.1349 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024620026
260 rdf:type schema:CreativeWork
261 https://doi.org/10.2169/internalmedicine.46.6188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023530366
262 rdf:type schema:CreativeWork
263 https://doi.org/10.3317/jraas.2000.059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032744835
264 rdf:type schema:CreativeWork
265 https://doi.org/10.4065/78.5.589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006383624
266 rdf:type schema:CreativeWork
267 https://doi.org/10.7326/0003-4819-118-4-199302150-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073697190
268 rdf:type schema:CreativeWork
269 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
270 schema:name Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
271 Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
272 rdf:type schema:Organization
273 https://www.grid.ac/institutes/grid.412708.8 schema:alternateName University of Tokyo Hospital
274 schema:name Department of Cell Therapy and Transplantation Medicine, University of Tokyo Hospital, Tokyo, Japan
275 Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
276 rdf:type schema:Organization
277 https://www.grid.ac/institutes/grid.54432.34 schema:alternateName Japan Society for the Promotion of Science
278 schema:name Department of Hematology and Oncology, Cell Therapy and Transplantation Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
279 The Japan Society for the Promotion of Science, Tokyo, Japan
280 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...