Risk factors for invasive aspergillosis and related mortality in recipients of allogeneic SCT from alternative donors: an analysis of 306 ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-03-23

AUTHORS

M Mikulska, A M Raiola, B Bruno, E Furfaro, M T Van Lint, S Bregante, A Ibatici, V Del Bono, A Bacigalupo, C Viscoli

ABSTRACT

Invasive aspergillosis (IA) is a serious complication in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT), particularly from donors other than HLA-identical sibling. All 306 patients who underwent alternative donor HSCT between 01 January 1999 and 31 December 2006 were studied. Late IA was defined as occurring ⩾40 days after HSCT. The median follow-up was 284 days (range, 1–2709). Donors were matched unrelated (n=185), mismatched related (n=69), mismatched unrelated (n=35) and unrelated cord blood (n=17). According to European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria, 2 patients already had IA at HSCT, 23 had early IA and 20 had late IA (IA incidence 15%). Eight patients had proven and 37 probable IA. Multivariate analyses showed that significant predictors of IA were delayed neutrophil engraftment, extensive chronic GVHD (cGVHD), secondary neutropenia and relapse after transplant. Early IA was associated with active malignancy at HSCT, CMV reactivation and delayed lymphocyte engraftment. Late IA was predicted by cGVHD, steroid therapy, secondary neutropenia and relapse after HSCT. IA-related mortality among IA patients was 67% and was influenced by use of anti-thymocyte globulin, steroids, higher levels of creatinine, and lower levels of IgA and platelets. The outcome of IA depends on the severity of immunodeficiency and the status of the underlying disease. More... »

PAGES

361-370

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bmt.2009.39

DOI

http://dx.doi.org/10.1038/bmt.2009.39

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049041418

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19308042


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aspergillosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Marrow Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cord Blood Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunocompromised Host", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kaplan-Meier Estimate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuroaspergillosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pulmonary Aspergillosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Statistics as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation Conditioning", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Homologous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5606.5", 
          "name": [
            "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mikulska", 
        "givenName": "M", 
        "id": "sg:person.01272344176.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272344176.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raiola", 
        "givenName": "A M", 
        "id": "sg:person.01031146215.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031146215.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bruno", 
        "givenName": "B", 
        "id": "sg:person.01163575446.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163575446.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5606.5", 
          "name": [
            "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Furfaro", 
        "givenName": "E", 
        "id": "sg:person.0771772576.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771772576.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Lint", 
        "givenName": "M T", 
        "id": "sg:person.010030501524.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010030501524.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bregante", 
        "givenName": "S", 
        "id": "sg:person.01177671722.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177671722.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ibatici", 
        "givenName": "A", 
        "id": "sg:person.066234013.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.066234013.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5606.5", 
          "name": [
            "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Del Bono", 
        "givenName": "V", 
        "id": "sg:person.0763033015.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763033015.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bacigalupo", 
        "givenName": "A", 
        "id": "sg:person.01366466656.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366466656.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5606.5", 
          "name": [
            "Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Viscoli", 
        "givenName": "C", 
        "id": "sg:person.01241060757.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241060757.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.bmt.1705989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002468461", 
          "https://doi.org/10.1038/sj.bmt.1705989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1703332", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009348005", 
          "https://doi.org/10.1038/sj.bmt.1703332"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1705167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009238510", 
          "https://doi.org/10.1038/sj.bmt.1705167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1700737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001726939", 
          "https://doi.org/10.1038/sj.bmt.1700737"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-03-23", 
    "datePublishedReg": "2009-03-23", 
    "description": "Invasive aspergillosis (IA) is a serious complication in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT), particularly from donors other than HLA-identical sibling. All 306 patients who underwent alternative donor HSCT between 01 January 1999 and 31 December 2006 were studied. Late IA was defined as occurring \u2a7e40 days after HSCT. The median follow-up was 284 days (range, 1\u20132709). Donors were matched unrelated (n=185), mismatched related (n=69), mismatched unrelated (n=35) and unrelated cord blood (n=17). According to European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria, 2 patients already had IA at HSCT, 23 had early IA and 20 had late IA (IA incidence 15%). Eight patients had proven and 37 probable IA. Multivariate analyses showed that significant predictors of IA were delayed neutrophil engraftment, extensive chronic GVHD (cGVHD), secondary neutropenia and relapse after transplant. Early IA was associated with active malignancy at HSCT, CMV reactivation and delayed lymphocyte engraftment. Late IA was predicted by cGVHD, steroid therapy, secondary neutropenia and relapse after HSCT. IA-related mortality among IA patients was 67% and was influenced by use of anti-thymocyte globulin, steroids, higher levels of creatinine, and lower levels of IgA and platelets. The outcome of IA depends on the severity of immunodeficiency and the status of the underlying disease.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/bmt.2009.39", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1096890", 
        "issn": [
          "0268-3369", 
          "1476-5365"
        ], 
        "name": "Bone Marrow Transplantation", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "44"
      }
    ], 
    "keywords": [
      "haematopoietic stem cell transplantation", 
      "Late Invasive Aspergillosis", 
      "early invasive aspergillosis", 
      "invasive aspergillosis", 
      "chronic GVHD", 
      "secondary neutropenia", 
      "Cancer/Mycoses Study Group criteria", 
      "donor haematopoietic stem cell transplantation", 
      "allogeneic haematopoietic stem cell transplantation", 
      "Mycoses Study Group criteria", 
      "outcome of IA", 
      "unrelated cord blood", 
      "extensive chronic GVHD", 
      "severity of immunodeficiency", 
      "anti-thymocyte globulin", 
      "HLA-identical siblings", 
      "Study Group criteria", 
      "probable invasive aspergillosis", 
      "stem cell transplantation", 
      "active malignancy", 
      "CMV reactivation", 
      "steroid therapy", 
      "neutrophil engraftment", 
      "allogeneic SCT", 
      "underlying disease", 
      "serious complications", 
      "lymphocyte engraftment", 
      "cell transplantation", 
      "Group criteria", 
      "risk factors", 
      "cord blood", 
      "related mortality", 
      "IA patients", 
      "alternative donors", 
      "patients", 
      "European Organization", 
      "multivariate analysis", 
      "significant predictors", 
      "neutropenia", 
      "relapse", 
      "aspergillosis", 
      "engraftment", 
      "mortality", 
      "low levels", 
      "days", 
      "donors", 
      "GVHD", 
      "high levels", 
      "complications", 
      "transplantation", 
      "creatinine", 
      "transplant", 
      "malignancy", 
      "IgA", 
      "immunodeficiency", 
      "therapy", 
      "steroids", 
      "disease", 
      "blood", 
      "globulin", 
      "severity", 
      "recipients", 
      "outcomes", 
      "SCT", 
      "platelets", 
      "treatment", 
      "levels", 
      "predictors", 
      "siblings", 
      "reactivation", 
      "status", 
      "Related", 
      "factors", 
      "criteria", 
      "analysis", 
      "use", 
      "research", 
      "organization"
    ], 
    "name": "Risk factors for invasive aspergillosis and related mortality in recipients of allogeneic SCT from alternative donors: an analysis of 306 patients", 
    "pagination": "361-370", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1049041418"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/bmt.2009.39"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19308042"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/bmt.2009.39", 
      "https://app.dimensions.ai/details/publication/pub.1049041418"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T20:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_475.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/bmt.2009.39"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/bmt.2009.39'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/bmt.2009.39'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/bmt.2009.39'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/bmt.2009.39'


 

This table displays all metadata directly associated to this object as RDF triples.

317 TRIPLES      21 PREDICATES      131 URIs      119 LITERALS      31 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/bmt.2009.39 schema:about N0a82752afaf546c9ac331b8ce31e4c18
2 N0f160f42c802495f9f931b76f21c5e45
3 N2d48b4c5679f4ec5bb6a1777d0793838
4 N402e61a4c9c54ece85223578cb6b5190
5 N42c61bc78bd94b618c023db5b49924d6
6 N4c6af6826152435091198bc21c8ecd6a
7 N5438267c08484199979b5b603fb6e592
8 N650787c2e9d446d2a37db66795c41591
9 N6746a2a71f9844499a323176103a8edd
10 N7f5171d1c3034563a8c43908b6e9cfb3
11 N9942d789ae4b4acd9271fe8f23de6466
12 N9d54e13a86ef4b39846ac6f958d24af0
13 Na4277599d752420ea5e79d433b80bbf6
14 Na5666187a7204a7eb1b4811d3ba02b1a
15 Na591d4129719414ea2c455250a9e15c0
16 Nb21a52b4915545c6aced86e9f0e80db4
17 Nb55c90e1c91e4f5e95d39410c2800818
18 Nb879b3597d7345faaf3d77e482771ffa
19 Nbf71faa5dd9e45cd9255c13a0bf05650
20 Nc61428656be64f69bd334f42cabb33ff
21 Nc748594d4bdd4e049df592c7dc981236
22 Nca3720ab02fc4b68860e210179020314
23 Nd265a33f12264f818a19284740a51516
24 Nec4fe45cf823477a925f37815ee5ffc5
25 anzsrc-for:11
26 anzsrc-for:1103
27 schema:author Nb8e34b0f6baa4c48b6e7ec1743d64996
28 schema:citation sg:pub.10.1038/sj.bmt.1700737
29 sg:pub.10.1038/sj.bmt.1703332
30 sg:pub.10.1038/sj.bmt.1705167
31 sg:pub.10.1038/sj.bmt.1705989
32 schema:datePublished 2009-03-23
33 schema:datePublishedReg 2009-03-23
34 schema:description Invasive aspergillosis (IA) is a serious complication in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT), particularly from donors other than HLA-identical sibling. All 306 patients who underwent alternative donor HSCT between 01 January 1999 and 31 December 2006 were studied. Late IA was defined as occurring ⩾40 days after HSCT. The median follow-up was 284 days (range, 1–2709). Donors were matched unrelated (n=185), mismatched related (n=69), mismatched unrelated (n=35) and unrelated cord blood (n=17). According to European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria, 2 patients already had IA at HSCT, 23 had early IA and 20 had late IA (IA incidence 15%). Eight patients had proven and 37 probable IA. Multivariate analyses showed that significant predictors of IA were delayed neutrophil engraftment, extensive chronic GVHD (cGVHD), secondary neutropenia and relapse after transplant. Early IA was associated with active malignancy at HSCT, CMV reactivation and delayed lymphocyte engraftment. Late IA was predicted by cGVHD, steroid therapy, secondary neutropenia and relapse after HSCT. IA-related mortality among IA patients was 67% and was influenced by use of anti-thymocyte globulin, steroids, higher levels of creatinine, and lower levels of IgA and platelets. The outcome of IA depends on the severity of immunodeficiency and the status of the underlying disease.
35 schema:genre article
36 schema:isAccessibleForFree false
37 schema:isPartOf N43d1f0706d7c41ac9a8ae84c14510e02
38 N61f7506c243a4c7486f4cec537823775
39 sg:journal.1096890
40 schema:keywords CMV reactivation
41 Cancer/Mycoses Study Group criteria
42 European Organization
43 GVHD
44 Group criteria
45 HLA-identical siblings
46 IA patients
47 IgA
48 Late Invasive Aspergillosis
49 Mycoses Study Group criteria
50 Related
51 SCT
52 Study Group criteria
53 active malignancy
54 allogeneic SCT
55 allogeneic haematopoietic stem cell transplantation
56 alternative donors
57 analysis
58 anti-thymocyte globulin
59 aspergillosis
60 blood
61 cell transplantation
62 chronic GVHD
63 complications
64 cord blood
65 creatinine
66 criteria
67 days
68 disease
69 donor haematopoietic stem cell transplantation
70 donors
71 early invasive aspergillosis
72 engraftment
73 extensive chronic GVHD
74 factors
75 globulin
76 haematopoietic stem cell transplantation
77 high levels
78 immunodeficiency
79 invasive aspergillosis
80 levels
81 low levels
82 lymphocyte engraftment
83 malignancy
84 mortality
85 multivariate analysis
86 neutropenia
87 neutrophil engraftment
88 organization
89 outcome of IA
90 outcomes
91 patients
92 platelets
93 predictors
94 probable invasive aspergillosis
95 reactivation
96 recipients
97 relapse
98 related mortality
99 research
100 risk factors
101 secondary neutropenia
102 serious complications
103 severity
104 severity of immunodeficiency
105 siblings
106 significant predictors
107 status
108 stem cell transplantation
109 steroid therapy
110 steroids
111 therapy
112 transplant
113 transplantation
114 treatment
115 underlying disease
116 unrelated cord blood
117 use
118 schema:name Risk factors for invasive aspergillosis and related mortality in recipients of allogeneic SCT from alternative donors: an analysis of 306 patients
119 schema:pagination 361-370
120 schema:productId N9bfdf50922a4474e830ef26dc9bbb55f
121 Nae498bb7dbec4b61ac41b186e1015874
122 Ndc4a438ca5fa4da2ae9801313cee8b98
123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049041418
124 https://doi.org/10.1038/bmt.2009.39
125 schema:sdDatePublished 2022-11-24T20:53
126 schema:sdLicense https://scigraph.springernature.com/explorer/license/
127 schema:sdPublisher N4cf5e485789a4b178710e2511a492901
128 schema:url https://doi.org/10.1038/bmt.2009.39
129 sgo:license sg:explorer/license/
130 sgo:sdDataset articles
131 rdf:type schema:ScholarlyArticle
132 N02ac27cb8e0d46e6b19f399ec8f83ae2 rdf:first sg:person.01177671722.63
133 rdf:rest Nbebcab530f0d47f9b75826ff27c59231
134 N0a82752afaf546c9ac331b8ce31e4c18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Kaplan-Meier Estimate
136 rdf:type schema:DefinedTerm
137 N0f160f42c802495f9f931b76f21c5e45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Disease Progression
139 rdf:type schema:DefinedTerm
140 N2b43c69e866743bebcc3864903b91b39 rdf:first sg:person.01163575446.29
141 rdf:rest Nfb324723981e413ba3e34c4cad0834d1
142 N2d48b4c5679f4ec5bb6a1777d0793838 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Statistics as Topic
144 rdf:type schema:DefinedTerm
145 N31e0cdfc64e943c2a0a301354bec22c3 rdf:first sg:person.01031146215.05
146 rdf:rest N2b43c69e866743bebcc3864903b91b39
147 N402e61a4c9c54ece85223578cb6b5190 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Cord Blood Stem Cell Transplantation
149 rdf:type schema:DefinedTerm
150 N42c61bc78bd94b618c023db5b49924d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Transplantation, Homologous
152 rdf:type schema:DefinedTerm
153 N43d1f0706d7c41ac9a8ae84c14510e02 schema:issueNumber 6
154 rdf:type schema:PublicationIssue
155 N4c6af6826152435091198bc21c8ecd6a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Humans
157 rdf:type schema:DefinedTerm
158 N4cf5e485789a4b178710e2511a492901 schema:name Springer Nature - SN SciGraph project
159 rdf:type schema:Organization
160 N5438267c08484199979b5b603fb6e592 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Bone Marrow Diseases
162 rdf:type schema:DefinedTerm
163 N5b589ba29f72443da4210c65b81e1f41 rdf:first sg:person.0763033015.43
164 rdf:rest Ne6097e240b5f4062b61f7160a0f433f3
165 N61f7506c243a4c7486f4cec537823775 schema:volumeNumber 44
166 rdf:type schema:PublicationVolume
167 N650787c2e9d446d2a37db66795c41591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Neuroaspergillosis
169 rdf:type schema:DefinedTerm
170 N6746a2a71f9844499a323176103a8edd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Adolescent
172 rdf:type schema:DefinedTerm
173 N7f5171d1c3034563a8c43908b6e9cfb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Female
175 rdf:type schema:DefinedTerm
176 N9942d789ae4b4acd9271fe8f23de6466 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Incidence
178 rdf:type schema:DefinedTerm
179 N9bfdf50922a4474e830ef26dc9bbb55f schema:name dimensions_id
180 schema:value pub.1049041418
181 rdf:type schema:PropertyValue
182 N9d54e13a86ef4b39846ac6f958d24af0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Pulmonary Aspergillosis
184 rdf:type schema:DefinedTerm
185 Na4277599d752420ea5e79d433b80bbf6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Risk Factors
187 rdf:type schema:DefinedTerm
188 Na5666187a7204a7eb1b4811d3ba02b1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Retrospective Studies
190 rdf:type schema:DefinedTerm
191 Na591d4129719414ea2c455250a9e15c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Immunocompromised Host
193 rdf:type schema:DefinedTerm
194 Na97baf2a39fc4c4c952f08131315fb54 rdf:first sg:person.01241060757.05
195 rdf:rest rdf:nil
196 Nae498bb7dbec4b61ac41b186e1015874 schema:name pubmed_id
197 schema:value 19308042
198 rdf:type schema:PropertyValue
199 Nb21a52b4915545c6aced86e9f0e80db4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Adult
201 rdf:type schema:DefinedTerm
202 Nb55c90e1c91e4f5e95d39410c2800818 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Hematopoietic Stem Cell Transplantation
204 rdf:type schema:DefinedTerm
205 Nb879b3597d7345faaf3d77e482771ffa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Treatment Outcome
207 rdf:type schema:DefinedTerm
208 Nb8e34b0f6baa4c48b6e7ec1743d64996 rdf:first sg:person.01272344176.57
209 rdf:rest N31e0cdfc64e943c2a0a301354bec22c3
210 Nbebcab530f0d47f9b75826ff27c59231 rdf:first sg:person.066234013.16
211 rdf:rest N5b589ba29f72443da4210c65b81e1f41
212 Nbf71faa5dd9e45cd9255c13a0bf05650 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
213 schema:name Aspergillosis
214 rdf:type schema:DefinedTerm
215 Nc61428656be64f69bd334f42cabb33ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
216 schema:name Time Factors
217 rdf:type schema:DefinedTerm
218 Nc748594d4bdd4e049df592c7dc981236 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
219 schema:name Young Adult
220 rdf:type schema:DefinedTerm
221 Nca3720ab02fc4b68860e210179020314 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
222 schema:name Middle Aged
223 rdf:type schema:DefinedTerm
224 Nd265a33f12264f818a19284740a51516 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
225 schema:name Transplantation Conditioning
226 rdf:type schema:DefinedTerm
227 Ndc4a438ca5fa4da2ae9801313cee8b98 schema:name doi
228 schema:value 10.1038/bmt.2009.39
229 rdf:type schema:PropertyValue
230 Ne6097e240b5f4062b61f7160a0f433f3 rdf:first sg:person.01366466656.47
231 rdf:rest Na97baf2a39fc4c4c952f08131315fb54
232 Nec4fe45cf823477a925f37815ee5ffc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
233 schema:name Male
234 rdf:type schema:DefinedTerm
235 Nf8f9e36dc817452f8b72f3d26dfa7679 rdf:first sg:person.010030501524.54
236 rdf:rest N02ac27cb8e0d46e6b19f399ec8f83ae2
237 Nfb324723981e413ba3e34c4cad0834d1 rdf:first sg:person.0771772576.73
238 rdf:rest Nf8f9e36dc817452f8b72f3d26dfa7679
239 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
240 schema:name Medical and Health Sciences
241 rdf:type schema:DefinedTerm
242 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
243 schema:name Clinical Sciences
244 rdf:type schema:DefinedTerm
245 sg:journal.1096890 schema:issn 0268-3369
246 1476-5365
247 schema:name Bone Marrow Transplantation
248 schema:publisher Springer Nature
249 rdf:type schema:Periodical
250 sg:person.010030501524.54 schema:affiliation grid-institutes:grid.410345.7
251 schema:familyName Van Lint
252 schema:givenName M T
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010030501524.54
254 rdf:type schema:Person
255 sg:person.01031146215.05 schema:affiliation grid-institutes:grid.410345.7
256 schema:familyName Raiola
257 schema:givenName A M
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031146215.05
259 rdf:type schema:Person
260 sg:person.01163575446.29 schema:affiliation grid-institutes:grid.410345.7
261 schema:familyName Bruno
262 schema:givenName B
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163575446.29
264 rdf:type schema:Person
265 sg:person.01177671722.63 schema:affiliation grid-institutes:grid.410345.7
266 schema:familyName Bregante
267 schema:givenName S
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177671722.63
269 rdf:type schema:Person
270 sg:person.01241060757.05 schema:affiliation grid-institutes:grid.5606.5
271 schema:familyName Viscoli
272 schema:givenName C
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241060757.05
274 rdf:type schema:Person
275 sg:person.01272344176.57 schema:affiliation grid-institutes:grid.5606.5
276 schema:familyName Mikulska
277 schema:givenName M
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272344176.57
279 rdf:type schema:Person
280 sg:person.01366466656.47 schema:affiliation grid-institutes:grid.410345.7
281 schema:familyName Bacigalupo
282 schema:givenName A
283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366466656.47
284 rdf:type schema:Person
285 sg:person.066234013.16 schema:affiliation grid-institutes:grid.410345.7
286 schema:familyName Ibatici
287 schema:givenName A
288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.066234013.16
289 rdf:type schema:Person
290 sg:person.0763033015.43 schema:affiliation grid-institutes:grid.5606.5
291 schema:familyName Del Bono
292 schema:givenName V
293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763033015.43
294 rdf:type schema:Person
295 sg:person.0771772576.73 schema:affiliation grid-institutes:grid.5606.5
296 schema:familyName Furfaro
297 schema:givenName E
298 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771772576.73
299 rdf:type schema:Person
300 sg:pub.10.1038/sj.bmt.1700737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001726939
301 https://doi.org/10.1038/sj.bmt.1700737
302 rdf:type schema:CreativeWork
303 sg:pub.10.1038/sj.bmt.1703332 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009348005
304 https://doi.org/10.1038/sj.bmt.1703332
305 rdf:type schema:CreativeWork
306 sg:pub.10.1038/sj.bmt.1705167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009238510
307 https://doi.org/10.1038/sj.bmt.1705167
308 rdf:type schema:CreativeWork
309 sg:pub.10.1038/sj.bmt.1705989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002468461
310 https://doi.org/10.1038/sj.bmt.1705989
311 rdf:type schema:CreativeWork
312 grid-institutes:grid.410345.7 schema:alternateName Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy
313 schema:name Division of Haematology and HSCT, San Martino Hospital, Genoa, Italy
314 rdf:type schema:Organization
315 grid-institutes:grid.5606.5 schema:alternateName Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy
316 schema:name Division of Infectious Diseases, San Martino University Hospital and University of Genoa, Genoa, Italy
317 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...