Anti-Mullerian hormone and endometrial cancer: a multi-cohort study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-09-05

AUTHORS

Renée T Fortner, Helena Schock, Seungyoun Jung, Naomi E Allen, Alan A Arslan, Louise A Brinton, Brian L Egleston, Roni T Falk, Marc J Gunter, Kathy J Helzlsouer, Annika Idahl, Theron S Johnson, Rudolf Kaaks, Vittorio Krogh, Eva Lundin, Melissa A Merritt, Carmen Navarro, N Charlotte Onland-Moret, Domenico Palli, Xiao-Ou Shu, Patrick M Sluss, Paul N Staats, Antonia Trichopoulou, Elisabete Weiderpass, Anne Zeleniuch-Jacquotte, Wei Zheng, Joanne F Dorgan

ABSTRACT

BACKGROUND: The Mullerian ducts are the embryological precursors of the female reproductive tract, including the uterus; anti-Mullerian hormone (AMH) has a key role in the regulation of foetal sexual differentiation. Anti-Mullerian hormone inhibits endometrial tumour growth in experimental models by stimulating apoptosis and cell cycle arrest. To date, there are no prospective epidemiologic data on circulating AMH and endometrial cancer risk. METHODS: We investigated this association among women premenopausal at blood collection in a multicohort study including participants from eight studies located in the United States, Europe, and China. We identified 329 endometrial cancer cases and 339 matched controls. Anti-Mullerian hormone concentrations in blood were quantified using an enzyme-linked immunosorbent assay. Conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CI) across tertiles and for a doubling of AMH concentrations (ORlog2). Subgroup analyses were performed by ages at blood donation and diagnosis, oral contraceptive use, and tumour characteristics. RESULTS: Anti-Mullerian hormone was not associated with the risk of endometrial cancer overall (ORlog2: 1.07 (0.99-1.17)), or with any of the examined subgroups. CONCLUSIONS: Although experimental models implicate AMH in endometrial cancer growth inhibition, our findings do not support a role for circulating AMH in the aetiology of endometrial cancer. More... »

PAGES

1412-1418

Journal

TITLE

British Journal of Cancer

ISSUE

9

VOLUME

117

Author Affiliations

  • Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.
  • Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Departments of Population Health and Environmental Medicine, New York University School of Medicine, New York University Perlmutter Cancer Center, New York, NY, USA.
  • Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
  • Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.
  • Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.
  • Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
  • Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
  • Department of Medical Biosciences and Pathology, Umeå University, Umeå, Sweden.
  • Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
  • Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain.
  • Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.
  • Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Department of Community Medicine, The Arctic University of Norway, Tromsø, Norway.
  • Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/bjc.2017.299

    DOI

    http://dx.doi.org/10.1038/bjc.2017.299

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1091488956

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28873086


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adenocarcinoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Anti-Mullerian Hormone", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biomarkers, Tumor", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Case-Control Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "China", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Endometrial Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Europe", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Follow-Up Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasm Grading", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasm Staging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prognosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "United States", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fortner", 
            "givenName": "Ren\u00e9e T", 
            "id": "sg:person.01046601661.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601661.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schock", 
            "givenName": "Helena", 
            "id": "sg:person.013267060423.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013267060423.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.411024.2", 
              "name": [
                "Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jung", 
            "givenName": "Seungyoun", 
            "id": "sg:person.0733072362.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733072362.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.", 
              "id": "http://www.grid.ac/institutes/grid.4991.5", 
              "name": [
                "Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Allen", 
            "givenName": "Naomi E", 
            "id": "sg:person.0577003004.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577003004.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Departments of Population Health and Environmental Medicine, New York University School of Medicine, New York University Perlmutter Cancer Center, New York, NY, USA.", 
              "id": "http://www.grid.ac/institutes/grid.137628.9", 
              "name": [
                "Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA.", 
                "Departments of Population Health and Environmental Medicine, New York University School of Medicine, New York University Perlmutter Cancer Center, New York, NY, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Arslan", 
            "givenName": "Alan A", 
            "id": "sg:person.01066036510.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066036510.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.48336.3a", 
              "name": [
                "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brinton", 
            "givenName": "Louise A", 
            "id": "sg:person.01263622305.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263622305.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Fox Chase Cancer Center, Philadelphia, PA, USA.", 
              "id": "http://www.grid.ac/institutes/grid.249335.a", 
              "name": [
                "Fox Chase Cancer Center, Philadelphia, PA, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Egleston", 
            "givenName": "Brian L", 
            "id": "sg:person.01224770141.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224770141.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.48336.3a", 
              "name": [
                "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Falk", 
            "givenName": "Roni T", 
            "id": "sg:person.0677052347.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677052347.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.", 
              "id": "http://www.grid.ac/institutes/grid.17703.32", 
              "name": [
                "Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gunter", 
            "givenName": "Marc J", 
            "id": "sg:person.015307142637.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015307142637.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.48336.3a", 
              "name": [
                "Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Helzlsouer", 
            "givenName": "Kathy J", 
            "id": "sg:person.01347433150.60", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347433150.60"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Clinical Sciences, Obstetrics and Gynecology, Ume\u00e5 University, Ume\u00e5, Sweden.", 
              "id": "http://www.grid.ac/institutes/grid.12650.30", 
              "name": [
                "Department of Clinical Sciences, Obstetrics and Gynecology, Ume\u00e5 University, Ume\u00e5, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Idahl", 
            "givenName": "Annika", 
            "id": "sg:person.0577712567.79", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577712567.79"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Johnson", 
            "givenName": "Theron S", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kaaks", 
            "givenName": "Rudolf", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.", 
              "id": "http://www.grid.ac/institutes/grid.417893.0", 
              "name": [
                "Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Krogh", 
            "givenName": "Vittorio", 
            "id": "sg:person.01240347722.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240347722.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medical Biosciences and Pathology, Ume\u00e5 University, Ume\u00e5, Sweden.", 
              "id": "http://www.grid.ac/institutes/grid.12650.30", 
              "name": [
                "Department of Medical Biosciences and Pathology, Ume\u00e5 University, Ume\u00e5, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lundin", 
            "givenName": "Eva", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.", 
              "id": "http://www.grid.ac/institutes/grid.7445.2", 
              "name": [
                "Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Merritt", 
            "givenName": "Melissa A", 
            "id": "sg:person.01371677602.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371677602.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain.", 
              "id": "http://www.grid.ac/institutes/grid.10586.3a", 
              "name": [
                "Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia, Spain.", 
                "CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, Spain.", 
                "Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Navarro", 
            "givenName": "Carmen", 
            "id": "sg:person.01072173750.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072173750.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.", 
              "id": "http://www.grid.ac/institutes/grid.7692.a", 
              "name": [
                "Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Onland-Moret", 
            "givenName": "N Charlotte", 
            "id": "sg:person.01354721144.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354721144.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.", 
              "id": "http://www.grid.ac/institutes/grid.417623.5", 
              "name": [
                "Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Palli", 
            "givenName": "Domenico", 
            "id": "sg:person.010014537677.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010014537677.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.", 
              "id": "http://www.grid.ac/institutes/grid.152326.1", 
              "name": [
                "Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shu", 
            "givenName": "Xiao-Ou", 
            "id": "sg:person.015003472057.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015003472057.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Pathology, Harvard Medical School, Boston, MA, USA.", 
              "id": "http://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Department of Pathology, Harvard Medical School, Boston, MA, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sluss", 
            "givenName": "Patrick M", 
            "id": "sg:person.016473244277.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016473244277.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.411024.2", 
              "name": [
                "Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Staats", 
            "givenName": "Paul N", 
            "id": "sg:person.01236743701.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236743701.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.", 
              "id": "http://www.grid.ac/institutes/grid.5216.0", 
              "name": [
                "Hellenic Health Foundation, Athens, Greece.", 
                "WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Trichopoulou", 
            "givenName": "Antonia", 
            "id": "sg:person.01017060476.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017060476.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Community Medicine, The Arctic University of Norway, Troms\u00f8, Norway.", 
              "id": "http://www.grid.ac/institutes/grid.10919.30", 
              "name": [
                "Department of Research, Group of Etiological Cancer Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway.", 
                "Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.", 
                "Genetic Epidemiology Group, Folkh\u00e4lsan Research Center, Helsinki, Finland.", 
                "Department of Community Medicine, The Arctic University of Norway, Troms\u00f8, Norway."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weiderpass", 
            "givenName": "Elisabete", 
            "id": "sg:person.01317176547.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317176547.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.", 
              "id": "http://www.grid.ac/institutes/grid.137628.9", 
              "name": [
                "Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zeleniuch-Jacquotte", 
            "givenName": "Anne", 
            "id": "sg:person.01221174140.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221174140.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.", 
              "id": "http://www.grid.ac/institutes/grid.152326.1", 
              "name": [
                "Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zheng", 
            "givenName": "Wei", 
            "id": "sg:person.016425765167.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016425765167.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.", 
              "id": "http://www.grid.ac/institutes/grid.411024.2", 
              "name": [
                "Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dorgan", 
            "givenName": "Joanne F", 
            "id": "sg:person.010434673257.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010434673257.14"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s12672-016-0258-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008220408", 
              "https://doi.org/10.1007/s12672-016-0258-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1756-9966-33-46", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007303702", 
              "https://doi.org/10.1186/1756-9966-33-46"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10549-008-0270-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019731947", 
              "https://doi.org/10.1007/s10549-008-0270-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10552-014-0363-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018932147", 
              "https://doi.org/10.1007/s10552-014-0363-9"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-09-05", 
        "datePublishedReg": "2017-09-05", 
        "description": "BACKGROUND: The Mullerian ducts are the embryological precursors of the female reproductive tract, including the uterus; anti-Mullerian hormone (AMH) has a key role in the regulation of foetal sexual differentiation. Anti-Mullerian hormone inhibits endometrial tumour growth in experimental models by stimulating apoptosis and cell cycle arrest. To date, there are no prospective epidemiologic data on circulating AMH and endometrial cancer risk.\nMETHODS: We investigated this association among women premenopausal at blood collection in a multicohort study including participants from eight studies located in the United States, Europe, and China. We identified 329 endometrial cancer cases and 339 matched controls. Anti-Mullerian hormone concentrations in blood were quantified using an enzyme-linked immunosorbent assay. Conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CI) across tertiles and for a doubling of AMH concentrations (ORlog2). Subgroup analyses were performed by ages at blood donation and diagnosis, oral contraceptive use, and tumour characteristics.\nRESULTS: Anti-Mullerian hormone was not associated with the risk of endometrial cancer overall (ORlog2: 1.07 (0.99-1.17)), or with any of the examined subgroups.\nCONCLUSIONS: Although experimental models implicate AMH in endometrial cancer growth inhibition, our findings do not support a role for circulating AMH in the aetiology of endometrial cancer.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/bjc.2017.299", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2724385", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2755349", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2482411", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5072449", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2774057", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2439079", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4293719", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2481630", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2438790", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2438822", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3866507", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4054803", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2476474", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3802734", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2634377", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1017082", 
            "issn": [
              "0007-0920", 
              "1532-1827"
            ], 
            "name": "British Journal of Cancer", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "9", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "117"
          }
        ], 
        "keywords": [
          "anti-Mullerian hormone", 
          "endometrial cancer", 
          "odds ratio", 
          "anti-Mullerian hormone concentrations", 
          "experimental model", 
          "prospective epidemiologic data", 
          "endometrial cancer risk", 
          "endometrial cancer cases", 
          "oral contraceptive use", 
          "endometrial tumor growth", 
          "confidence intervals", 
          "conditional logistic regression", 
          "cancer growth inhibition", 
          "enzyme-linked immunosorbent", 
          "multi-cohort study", 
          "female reproductive tract", 
          "cancer overall", 
          "tumor characteristics", 
          "AMH concentrations", 
          "subgroup analysis", 
          "epidemiologic data", 
          "cell cycle arrest", 
          "multicohort study", 
          "cancer cases", 
          "contraceptive use", 
          "cancer risk", 
          "hormone concentrations", 
          "tumor growth", 
          "Mullerian ducts", 
          "blood donation", 
          "embryological precursors", 
          "blood collection", 
          "logistic regression", 
          "reproductive tract", 
          "hormone", 
          "cycle arrest", 
          "cancer", 
          "growth inhibition", 
          "sexual differentiation", 
          "risk", 
          "tertile", 
          "uterus", 
          "etiology", 
          "immunosorbent", 
          "diagnosis", 
          "blood", 
          "tract", 
          "study", 
          "women", 
          "key role", 
          "Overall", 
          "age", 
          "United States", 
          "subgroups", 
          "arrest", 
          "apoptosis", 
          "inhibition", 
          "duct", 
          "role", 
          "association", 
          "participants", 
          "donation", 
          "regression", 
          "concentration", 
          "findings", 
          "intervals", 
          "differentiation", 
          "control", 
          "cases", 
          "regulation", 
          "date", 
          "use", 
          "doubling", 
          "data", 
          "ratio", 
          "analysis", 
          "growth", 
          "model", 
          "characteristics", 
          "collection", 
          "precursors", 
          "Europe", 
          "state", 
          "China", 
          "foetal sexual differentiation", 
          "endometrial cancer overall", 
          "endometrial cancer growth inhibition"
        ], 
        "name": "Anti-Mullerian hormone and endometrial cancer: a multi-cohort study", 
        "pagination": "1412-1418", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1091488956"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/bjc.2017.299"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "28873086"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/bjc.2017.299", 
          "https://app.dimensions.ai/details/publication/pub.1091488956"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-01-01T18:45", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_733.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/bjc.2017.299"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/bjc.2017.299'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/bjc.2017.299'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/bjc.2017.299'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/bjc.2017.299'


     

    This table displays all metadata directly associated to this object as RDF triples.

    505 TRIPLES      22 PREDICATES      134 URIs      122 LITERALS      24 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/bjc.2017.299 schema:about N0b74ff0b22714e8c8d5f3e86454b45c3
    2 N38602c8e2b4843a38e8daa2f62d71669
    3 N50122ad7f54a42b4b29ef0cc8fdef7e6
    4 N6ffe982c39f94b47b6c3cbed0fe13680
    5 N729e680060174674baf2abce590ffafa
    6 N79ce8118d0764b9b94acd006f236c8d0
    7 N8a30d55f8462497fb018920ea05eaa78
    8 N8c5b948f9135477b83080bdcdfe1aa5d
    9 N9c8919ad1ea9405bb61658df0c1bc70c
    10 Nbb7e3f552ccd4bd8b2c2eef78cec66a6
    11 Nc7c603ac244e4353bdc7ac73bfc55313
    12 Ndf78a5a172fc402cbe99a46e45b53af3
    13 Ne83fa135608742518c22414f7f53d87c
    14 Nef13c11773bb429a86a8b3e1eefc819f
    15 Nf5798655645347b5adee1408acb329e3
    16 Nf7d85c309c3840d691123ba4c7f670ae
    17 Nf86ce6c8dd014653a7dc93b47526c114
    18 anzsrc-for:11
    19 anzsrc-for:1112
    20 schema:author Nddeb253147884ac98bc9235e0eb083b1
    21 schema:citation sg:pub.10.1007/s10549-008-0270-4
    22 sg:pub.10.1007/s10552-014-0363-9
    23 sg:pub.10.1007/s12672-016-0258-1
    24 sg:pub.10.1186/1756-9966-33-46
    25 schema:datePublished 2017-09-05
    26 schema:datePublishedReg 2017-09-05
    27 schema:description BACKGROUND: The Mullerian ducts are the embryological precursors of the female reproductive tract, including the uterus; anti-Mullerian hormone (AMH) has a key role in the regulation of foetal sexual differentiation. Anti-Mullerian hormone inhibits endometrial tumour growth in experimental models by stimulating apoptosis and cell cycle arrest. To date, there are no prospective epidemiologic data on circulating AMH and endometrial cancer risk. METHODS: We investigated this association among women premenopausal at blood collection in a multicohort study including participants from eight studies located in the United States, Europe, and China. We identified 329 endometrial cancer cases and 339 matched controls. Anti-Mullerian hormone concentrations in blood were quantified using an enzyme-linked immunosorbent assay. Conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CI) across tertiles and for a doubling of AMH concentrations (OR<sub>log2</sub>). Subgroup analyses were performed by ages at blood donation and diagnosis, oral contraceptive use, and tumour characteristics. RESULTS: Anti-Mullerian hormone was not associated with the risk of endometrial cancer overall (OR<sub>log2</sub>: 1.07 (0.99-1.17)), or with any of the examined subgroups. CONCLUSIONS: Although experimental models implicate AMH in endometrial cancer growth inhibition, our findings do not support a role for circulating AMH in the aetiology of endometrial cancer.
    28 schema:genre article
    29 schema:inLanguage en
    30 schema:isAccessibleForFree true
    31 schema:isPartOf N8808005c9df641ce9ebcaa1cc32aedb9
    32 N89a2b81c594e4274a988e0bb6fa0a802
    33 sg:journal.1017082
    34 schema:keywords AMH concentrations
    35 China
    36 Europe
    37 Mullerian ducts
    38 Overall
    39 United States
    40 age
    41 analysis
    42 anti-Mullerian hormone
    43 anti-Mullerian hormone concentrations
    44 apoptosis
    45 arrest
    46 association
    47 blood
    48 blood collection
    49 blood donation
    50 cancer
    51 cancer cases
    52 cancer growth inhibition
    53 cancer overall
    54 cancer risk
    55 cases
    56 cell cycle arrest
    57 characteristics
    58 collection
    59 concentration
    60 conditional logistic regression
    61 confidence intervals
    62 contraceptive use
    63 control
    64 cycle arrest
    65 data
    66 date
    67 diagnosis
    68 differentiation
    69 donation
    70 doubling
    71 duct
    72 embryological precursors
    73 endometrial cancer
    74 endometrial cancer cases
    75 endometrial cancer growth inhibition
    76 endometrial cancer overall
    77 endometrial cancer risk
    78 endometrial tumor growth
    79 enzyme-linked immunosorbent
    80 epidemiologic data
    81 etiology
    82 experimental model
    83 female reproductive tract
    84 findings
    85 foetal sexual differentiation
    86 growth
    87 growth inhibition
    88 hormone
    89 hormone concentrations
    90 immunosorbent
    91 inhibition
    92 intervals
    93 key role
    94 logistic regression
    95 model
    96 multi-cohort study
    97 multicohort study
    98 odds ratio
    99 oral contraceptive use
    100 participants
    101 precursors
    102 prospective epidemiologic data
    103 ratio
    104 regression
    105 regulation
    106 reproductive tract
    107 risk
    108 role
    109 sexual differentiation
    110 state
    111 study
    112 subgroup analysis
    113 subgroups
    114 tertile
    115 tract
    116 tumor characteristics
    117 tumor growth
    118 use
    119 uterus
    120 women
    121 schema:name Anti-Mullerian hormone and endometrial cancer: a multi-cohort study
    122 schema:pagination 1412-1418
    123 schema:productId N2a5f1c16cfb441a090c61010923d6bde
    124 N8838f4723ee0471d9c9569585c16215c
    125 Nec693a71ccfa4bceace66657db2adbeb
    126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091488956
    127 https://doi.org/10.1038/bjc.2017.299
    128 schema:sdDatePublished 2022-01-01T18:45
    129 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    130 schema:sdPublisher Na9e3af6dead94badbc78c1e75e941eb0
    131 schema:url https://doi.org/10.1038/bjc.2017.299
    132 sgo:license sg:explorer/license/
    133 sgo:sdDataset articles
    134 rdf:type schema:ScholarlyArticle
    135 N001b9643eb59418dae79251a6769c193 rdf:first sg:person.010014537677.09
    136 rdf:rest N764c03e34fd34da184e17caeac55c9b2
    137 N03685241f5434d0f92b9e29b93d4e8af rdf:first sg:person.0677052347.29
    138 rdf:rest Nb2051dccf0fc4192adcd40a73076eab7
    139 N09733fa01a9a4f9fa705d84b16743e95 rdf:first sg:person.010434673257.14
    140 rdf:rest rdf:nil
    141 N0b74ff0b22714e8c8d5f3e86454b45c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    142 schema:name Female
    143 rdf:type schema:DefinedTerm
    144 N0d4665e5b89d4df58673e0ad44b6c661 rdf:first sg:person.01347433150.60
    145 rdf:rest N7981d98feb6a48c883a1181bb284b02c
    146 N2a5f1c16cfb441a090c61010923d6bde schema:name dimensions_id
    147 schema:value pub.1091488956
    148 rdf:type schema:PropertyValue
    149 N3434259a586a4945a3d239d24ba9da74 rdf:first sg:person.01317176547.68
    150 rdf:rest N6933f215ba434c56a56883fea9938c4a
    151 N38602c8e2b4843a38e8daa2f62d71669 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Endometrial Neoplasms
    153 rdf:type schema:DefinedTerm
    154 N3da29575cc69442c94e19bbd19e40981 rdf:first sg:person.01371677602.75
    155 rdf:rest Ndd33b65e320b494f85c527f514f0f113
    156 N475ff9268521436cae13627074dd83b5 rdf:first sg:person.013267060423.27
    157 rdf:rest N6af280db050843d4b68a225c60f66888
    158 N4ddc9aad7768492b8bd9c1a734105dc6 rdf:first sg:person.01066036510.50
    159 rdf:rest Ncb0d5ccea11c45d7a5353f46537d2d9f
    160 N50122ad7f54a42b4b29ef0cc8fdef7e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Neoplasm Staging
    162 rdf:type schema:DefinedTerm
    163 N6933f215ba434c56a56883fea9938c4a rdf:first sg:person.01221174140.50
    164 rdf:rest N9ada3702d5ce45ee9c12d662b36df612
    165 N6af280db050843d4b68a225c60f66888 rdf:first sg:person.0733072362.09
    166 rdf:rest N9cd5771fc9da40a39b909789e1e24162
    167 N6ffe982c39f94b47b6c3cbed0fe13680 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    168 schema:name Adenocarcinoma
    169 rdf:type schema:DefinedTerm
    170 N729e680060174674baf2abce590ffafa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Europe
    172 rdf:type schema:DefinedTerm
    173 N764c03e34fd34da184e17caeac55c9b2 rdf:first sg:person.015003472057.84
    174 rdf:rest N8429988a18f241faadf339a938a090e8
    175 N780420a0e0a6426f8a5cfcb585af8d2e rdf:first N836a01411a18465e8f1911abb8daf364
    176 rdf:rest N3da29575cc69442c94e19bbd19e40981
    177 N7981d98feb6a48c883a1181bb284b02c rdf:first sg:person.0577712567.79
    178 rdf:rest Nd1eb5c51e5314d278092c7449a687064
    179 N79ce8118d0764b9b94acd006f236c8d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    180 schema:name Neoplasm Grading
    181 rdf:type schema:DefinedTerm
    182 N836a01411a18465e8f1911abb8daf364 schema:affiliation grid-institutes:grid.12650.30
    183 schema:familyName Lundin
    184 schema:givenName Eva
    185 rdf:type schema:Person
    186 N8429988a18f241faadf339a938a090e8 rdf:first sg:person.016473244277.87
    187 rdf:rest Nbcbbe2a7342945ac84c252732bd0e6f7
    188 N8808005c9df641ce9ebcaa1cc32aedb9 schema:issueNumber 9
    189 rdf:type schema:PublicationIssue
    190 N8838f4723ee0471d9c9569585c16215c schema:name pubmed_id
    191 schema:value 28873086
    192 rdf:type schema:PropertyValue
    193 N89a2b81c594e4274a988e0bb6fa0a802 schema:volumeNumber 117
    194 rdf:type schema:PublicationVolume
    195 N8a30d55f8462497fb018920ea05eaa78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    196 schema:name Follow-Up Studies
    197 rdf:type schema:DefinedTerm
    198 N8c5b948f9135477b83080bdcdfe1aa5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    199 schema:name Biomarkers, Tumor
    200 rdf:type schema:DefinedTerm
    201 N8ea072afec0f41eba32db7e127596b55 rdf:first sg:person.01240347722.67
    202 rdf:rest N780420a0e0a6426f8a5cfcb585af8d2e
    203 N9720aab6c5b942eebbf9849cb24e506a rdf:first sg:person.01017060476.31
    204 rdf:rest N3434259a586a4945a3d239d24ba9da74
    205 N99869c3cde5f4e4da00faa23ffa08ea4 rdf:first sg:person.01354721144.29
    206 rdf:rest N001b9643eb59418dae79251a6769c193
    207 N9ada3702d5ce45ee9c12d662b36df612 rdf:first sg:person.016425765167.70
    208 rdf:rest N09733fa01a9a4f9fa705d84b16743e95
    209 N9c8919ad1ea9405bb61658df0c1bc70c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    210 schema:name Prospective Studies
    211 rdf:type schema:DefinedTerm
    212 N9cd5771fc9da40a39b909789e1e24162 rdf:first sg:person.0577003004.68
    213 rdf:rest N4ddc9aad7768492b8bd9c1a734105dc6
    214 Na93ebd24b0b245f9bec69daf126963dd schema:affiliation grid-institutes:None
    215 schema:familyName Johnson
    216 schema:givenName Theron S
    217 rdf:type schema:Person
    218 Na9e3af6dead94badbc78c1e75e941eb0 schema:name Springer Nature - SN SciGraph project
    219 rdf:type schema:Organization
    220 Naa9c33252a574399a981b643c137ac45 rdf:first Nd5dd625c1e4f4c70b74cf4d8ff408dd9
    221 rdf:rest N8ea072afec0f41eba32db7e127596b55
    222 Nb2051dccf0fc4192adcd40a73076eab7 rdf:first sg:person.015307142637.30
    223 rdf:rest N0d4665e5b89d4df58673e0ad44b6c661
    224 Nb87fd044706e491397a3959f5176aa23 rdf:first sg:person.01224770141.97
    225 rdf:rest N03685241f5434d0f92b9e29b93d4e8af
    226 Nbb7e3f552ccd4bd8b2c2eef78cec66a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    227 schema:name Anti-Mullerian Hormone
    228 rdf:type schema:DefinedTerm
    229 Nbcbbe2a7342945ac84c252732bd0e6f7 rdf:first sg:person.01236743701.08
    230 rdf:rest N9720aab6c5b942eebbf9849cb24e506a
    231 Nc7c603ac244e4353bdc7ac73bfc55313 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    232 schema:name China
    233 rdf:type schema:DefinedTerm
    234 Ncb0d5ccea11c45d7a5353f46537d2d9f rdf:first sg:person.01263622305.88
    235 rdf:rest Nb87fd044706e491397a3959f5176aa23
    236 Nd1eb5c51e5314d278092c7449a687064 rdf:first Na93ebd24b0b245f9bec69daf126963dd
    237 rdf:rest Naa9c33252a574399a981b643c137ac45
    238 Nd5dd625c1e4f4c70b74cf4d8ff408dd9 schema:affiliation grid-institutes:None
    239 schema:familyName Kaaks
    240 schema:givenName Rudolf
    241 rdf:type schema:Person
    242 Ndd33b65e320b494f85c527f514f0f113 rdf:first sg:person.01072173750.77
    243 rdf:rest N99869c3cde5f4e4da00faa23ffa08ea4
    244 Nddeb253147884ac98bc9235e0eb083b1 rdf:first sg:person.01046601661.53
    245 rdf:rest N475ff9268521436cae13627074dd83b5
    246 Ndf78a5a172fc402cbe99a46e45b53af3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    247 schema:name Prognosis
    248 rdf:type schema:DefinedTerm
    249 Ne83fa135608742518c22414f7f53d87c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    250 schema:name Case-Control Studies
    251 rdf:type schema:DefinedTerm
    252 Nec693a71ccfa4bceace66657db2adbeb schema:name doi
    253 schema:value 10.1038/bjc.2017.299
    254 rdf:type schema:PropertyValue
    255 Nef13c11773bb429a86a8b3e1eefc819f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    256 schema:name United States
    257 rdf:type schema:DefinedTerm
    258 Nf5798655645347b5adee1408acb329e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    259 schema:name Humans
    260 rdf:type schema:DefinedTerm
    261 Nf7d85c309c3840d691123ba4c7f670ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    262 schema:name Middle Aged
    263 rdf:type schema:DefinedTerm
    264 Nf86ce6c8dd014653a7dc93b47526c114 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    265 schema:name Adult
    266 rdf:type schema:DefinedTerm
    267 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    268 schema:name Medical and Health Sciences
    269 rdf:type schema:DefinedTerm
    270 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    271 schema:name Oncology and Carcinogenesis
    272 rdf:type schema:DefinedTerm
    273 sg:grant.2438790 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    274 rdf:type schema:MonetaryGrant
    275 sg:grant.2438822 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    276 rdf:type schema:MonetaryGrant
    277 sg:grant.2439079 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    278 rdf:type schema:MonetaryGrant
    279 sg:grant.2476474 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    280 rdf:type schema:MonetaryGrant
    281 sg:grant.2481630 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    282 rdf:type schema:MonetaryGrant
    283 sg:grant.2482411 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    284 rdf:type schema:MonetaryGrant
    285 sg:grant.2634377 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    286 rdf:type schema:MonetaryGrant
    287 sg:grant.2724385 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    288 rdf:type schema:MonetaryGrant
    289 sg:grant.2755349 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    290 rdf:type schema:MonetaryGrant
    291 sg:grant.2774057 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    292 rdf:type schema:MonetaryGrant
    293 sg:grant.3802734 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    294 rdf:type schema:MonetaryGrant
    295 sg:grant.3866507 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    296 rdf:type schema:MonetaryGrant
    297 sg:grant.4054803 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    298 rdf:type schema:MonetaryGrant
    299 sg:grant.4293719 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    300 rdf:type schema:MonetaryGrant
    301 sg:grant.5072449 http://pending.schema.org/fundedItem sg:pub.10.1038/bjc.2017.299
    302 rdf:type schema:MonetaryGrant
    303 sg:journal.1017082 schema:issn 0007-0920
    304 1532-1827
    305 schema:name British Journal of Cancer
    306 schema:publisher Springer Nature
    307 rdf:type schema:Periodical
    308 sg:person.010014537677.09 schema:affiliation grid-institutes:grid.417623.5
    309 schema:familyName Palli
    310 schema:givenName Domenico
    311 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010014537677.09
    312 rdf:type schema:Person
    313 sg:person.01017060476.31 schema:affiliation grid-institutes:grid.5216.0
    314 schema:familyName Trichopoulou
    315 schema:givenName Antonia
    316 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017060476.31
    317 rdf:type schema:Person
    318 sg:person.010434673257.14 schema:affiliation grid-institutes:grid.411024.2
    319 schema:familyName Dorgan
    320 schema:givenName Joanne F
    321 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010434673257.14
    322 rdf:type schema:Person
    323 sg:person.01046601661.53 schema:affiliation grid-institutes:None
    324 schema:familyName Fortner
    325 schema:givenName Renée T
    326 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601661.53
    327 rdf:type schema:Person
    328 sg:person.01066036510.50 schema:affiliation grid-institutes:grid.137628.9
    329 schema:familyName Arslan
    330 schema:givenName Alan A
    331 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066036510.50
    332 rdf:type schema:Person
    333 sg:person.01072173750.77 schema:affiliation grid-institutes:grid.10586.3a
    334 schema:familyName Navarro
    335 schema:givenName Carmen
    336 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072173750.77
    337 rdf:type schema:Person
    338 sg:person.01221174140.50 schema:affiliation grid-institutes:grid.137628.9
    339 schema:familyName Zeleniuch-Jacquotte
    340 schema:givenName Anne
    341 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221174140.50
    342 rdf:type schema:Person
    343 sg:person.01224770141.97 schema:affiliation grid-institutes:grid.249335.a
    344 schema:familyName Egleston
    345 schema:givenName Brian L
    346 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224770141.97
    347 rdf:type schema:Person
    348 sg:person.01236743701.08 schema:affiliation grid-institutes:grid.411024.2
    349 schema:familyName Staats
    350 schema:givenName Paul N
    351 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236743701.08
    352 rdf:type schema:Person
    353 sg:person.01240347722.67 schema:affiliation grid-institutes:grid.417893.0
    354 schema:familyName Krogh
    355 schema:givenName Vittorio
    356 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240347722.67
    357 rdf:type schema:Person
    358 sg:person.01263622305.88 schema:affiliation grid-institutes:grid.48336.3a
    359 schema:familyName Brinton
    360 schema:givenName Louise A
    361 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263622305.88
    362 rdf:type schema:Person
    363 sg:person.01317176547.68 schema:affiliation grid-institutes:grid.10919.30
    364 schema:familyName Weiderpass
    365 schema:givenName Elisabete
    366 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317176547.68
    367 rdf:type schema:Person
    368 sg:person.013267060423.27 schema:affiliation grid-institutes:None
    369 schema:familyName Schock
    370 schema:givenName Helena
    371 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013267060423.27
    372 rdf:type schema:Person
    373 sg:person.01347433150.60 schema:affiliation grid-institutes:grid.48336.3a
    374 schema:familyName Helzlsouer
    375 schema:givenName Kathy J
    376 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347433150.60
    377 rdf:type schema:Person
    378 sg:person.01354721144.29 schema:affiliation grid-institutes:grid.7692.a
    379 schema:familyName Onland-Moret
    380 schema:givenName N Charlotte
    381 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354721144.29
    382 rdf:type schema:Person
    383 sg:person.01371677602.75 schema:affiliation grid-institutes:grid.7445.2
    384 schema:familyName Merritt
    385 schema:givenName Melissa A
    386 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371677602.75
    387 rdf:type schema:Person
    388 sg:person.015003472057.84 schema:affiliation grid-institutes:grid.152326.1
    389 schema:familyName Shu
    390 schema:givenName Xiao-Ou
    391 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015003472057.84
    392 rdf:type schema:Person
    393 sg:person.015307142637.30 schema:affiliation grid-institutes:grid.17703.32
    394 schema:familyName Gunter
    395 schema:givenName Marc J
    396 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015307142637.30
    397 rdf:type schema:Person
    398 sg:person.016425765167.70 schema:affiliation grid-institutes:grid.152326.1
    399 schema:familyName Zheng
    400 schema:givenName Wei
    401 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016425765167.70
    402 rdf:type schema:Person
    403 sg:person.016473244277.87 schema:affiliation grid-institutes:grid.38142.3c
    404 schema:familyName Sluss
    405 schema:givenName Patrick M
    406 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016473244277.87
    407 rdf:type schema:Person
    408 sg:person.0577003004.68 schema:affiliation grid-institutes:grid.4991.5
    409 schema:familyName Allen
    410 schema:givenName Naomi E
    411 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577003004.68
    412 rdf:type schema:Person
    413 sg:person.0577712567.79 schema:affiliation grid-institutes:grid.12650.30
    414 schema:familyName Idahl
    415 schema:givenName Annika
    416 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577712567.79
    417 rdf:type schema:Person
    418 sg:person.0677052347.29 schema:affiliation grid-institutes:grid.48336.3a
    419 schema:familyName Falk
    420 schema:givenName Roni T
    421 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677052347.29
    422 rdf:type schema:Person
    423 sg:person.0733072362.09 schema:affiliation grid-institutes:grid.411024.2
    424 schema:familyName Jung
    425 schema:givenName Seungyoun
    426 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733072362.09
    427 rdf:type schema:Person
    428 sg:pub.10.1007/s10549-008-0270-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019731947
    429 https://doi.org/10.1007/s10549-008-0270-4
    430 rdf:type schema:CreativeWork
    431 sg:pub.10.1007/s10552-014-0363-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018932147
    432 https://doi.org/10.1007/s10552-014-0363-9
    433 rdf:type schema:CreativeWork
    434 sg:pub.10.1007/s12672-016-0258-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008220408
    435 https://doi.org/10.1007/s12672-016-0258-1
    436 rdf:type schema:CreativeWork
    437 sg:pub.10.1186/1756-9966-33-46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007303702
    438 https://doi.org/10.1186/1756-9966-33-46
    439 rdf:type schema:CreativeWork
    440 grid-institutes:None schema:alternateName Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.
    441 schema:name Division of Cancer Epidemiology, German Cancer Research Cancer, Heidelberg, Germany.
    442 rdf:type schema:Organization
    443 grid-institutes:grid.10586.3a schema:alternateName Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain.
    444 schema:name CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
    445 Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia, Spain.
    446 Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain.
    447 rdf:type schema:Organization
    448 grid-institutes:grid.10919.30 schema:alternateName Department of Community Medicine, The Arctic University of Norway, Tromsø, Norway.
    449 schema:name Department of Community Medicine, The Arctic University of Norway, Tromsø, Norway.
    450 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    451 Department of Research, Group of Etiological Cancer Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway.
    452 Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland.
    453 rdf:type schema:Organization
    454 grid-institutes:grid.12650.30 schema:alternateName Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
    455 Department of Medical Biosciences and Pathology, Umeå University, Umeå, Sweden.
    456 schema:name Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
    457 Department of Medical Biosciences and Pathology, Umeå University, Umeå, Sweden.
    458 rdf:type schema:Organization
    459 grid-institutes:grid.137628.9 schema:alternateName Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.
    460 Departments of Population Health and Environmental Medicine, New York University School of Medicine, New York University Perlmutter Cancer Center, New York, NY, USA.
    461 schema:name Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA.
    462 Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.
    463 Departments of Population Health and Environmental Medicine, New York University School of Medicine, New York University Perlmutter Cancer Center, New York, NY, USA.
    464 rdf:type schema:Organization
    465 grid-institutes:grid.152326.1 schema:alternateName Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
    466 schema:name Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
    467 rdf:type schema:Organization
    468 grid-institutes:grid.17703.32 schema:alternateName Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.
    469 schema:name Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.
    470 rdf:type schema:Organization
    471 grid-institutes:grid.249335.a schema:alternateName Fox Chase Cancer Center, Philadelphia, PA, USA.
    472 schema:name Fox Chase Cancer Center, Philadelphia, PA, USA.
    473 rdf:type schema:Organization
    474 grid-institutes:grid.38142.3c schema:alternateName Department of Pathology, Harvard Medical School, Boston, MA, USA.
    475 schema:name Department of Pathology, Harvard Medical School, Boston, MA, USA.
    476 rdf:type schema:Organization
    477 grid-institutes:grid.411024.2 schema:alternateName Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
    478 Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
    479 schema:name Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
    480 Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
    481 rdf:type schema:Organization
    482 grid-institutes:grid.417623.5 schema:alternateName Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.
    483 schema:name Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.
    484 rdf:type schema:Organization
    485 grid-institutes:grid.417893.0 schema:alternateName Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
    486 schema:name Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
    487 rdf:type schema:Organization
    488 grid-institutes:grid.48336.3a schema:alternateName Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.
    489 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
    490 schema:name Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.
    491 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
    492 rdf:type schema:Organization
    493 grid-institutes:grid.4991.5 schema:alternateName Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
    494 schema:name Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
    495 rdf:type schema:Organization
    496 grid-institutes:grid.5216.0 schema:alternateName WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
    497 schema:name Hellenic Health Foundation, Athens, Greece.
    498 WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
    499 rdf:type schema:Organization
    500 grid-institutes:grid.7445.2 schema:alternateName Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
    501 schema:name Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
    502 rdf:type schema:Organization
    503 grid-institutes:grid.7692.a schema:alternateName Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
    504 schema:name Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
    505 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...