Loss of partner and breast cancer prognosis — a population-based study, Denmark, 1994–2010 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-04

AUTHORS

M H Olsen, P E Bidstrup, K Frederiksen, N H Rod, M Grønbæk, S O Dalton, C Johansen

ABSTRACT

BACKGROUND: The extent to which experiencing a stressful life event influences breast cancer prognosis remains unknown, as the findings of the few previous epidemiological studies are inconsistent. This large population-based study examines the association between a common major life event, loss of a partner and breast cancer recurrence and all-cause mortality. METHODS: N=21,213 women diagnosed with a first primary breast cancer 1994-2006, who had a cohabiting partner in the 4 years before their breast cancer diagnosis, were followed for death and recurrence in population-based registers and clinical databases. Information on education, disposable income, comorbidity and prognostic risk factors were included in Cox regression analyses. RESULTS: Women who had lost a partner either before diagnosis or in subsequent years were not at significantly higher risk of recurrence or dying than women who had not lost a partner. CONCLUSION: Our results do not support the concern that experiencing a stressful life event, the loss of a partner, negatively affects prognosis of breast cancer. More... »

PAGES

1560

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bjc.2012.96

DOI

http://dx.doi.org/10.1038/bjc.2012.96

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042870915

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22433966


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