An objective biochemical assessment of therapeutic response in metastatic breast cancer: a study with external review of clinical data View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1990-01

AUTHORS

M R Williams, A Turkes, D Pearson, K Griffiths, R W Blamey

ABSTRACT

A series of tumour related markers have been examined in 179 patients receiving primary endocrine therapy for metastatic breast cancer. Significant correlations between therapeutic response (UICC criteria after 6 months of treatment) and appropriate alterations in serum concentrations of carcinoembryonic antigen, ferritin, c-reactive protein, orosomucoid and the erythrocyte sedimentation rate, have been observed when changes in these markers were examined only at high serum concentrations. By combining these five markers a 'therapeutic index' of response has been devised which can be employed at an early stage of treatment in more than 90% of patients, giving an overall sensitivity/specificity of 90%/78% for therapeutic response or disease stabilisation over a 6-month period. The design of an objective measurement of response, which is easy to perform, has the potential to replace the existing, largely subjective. UICC criteria for retrospective judgement of response, and may also be used to direct systemic endocrine therapy. More... »

PAGES

126

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bjc.1990.26

DOI

http://dx.doi.org/10.1038/bjc.1990.26

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029956355

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2137007


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Sedimentation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Buserelin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "C-Reactive Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoembryonic Antigen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ferritins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Goserelin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lung Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Megestrol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Megestrol Acetate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Orosomucoid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovariectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tamoxifen", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Nottingham City Hospital, UK."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Williams", 
        "givenName": "M R", 
        "id": "sg:person.0747422207.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747422207.13"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Turkes", 
        "givenName": "A", 
        "id": "sg:person.01204571037.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204571037.12"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Pearson", 
        "givenName": "D", 
        "id": "sg:person.01107407472.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107407472.00"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Griffiths", 
        "givenName": "K", 
        "id": "sg:person.01112542605.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112542605.67"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Blamey", 
        "givenName": "R W", 
        "id": "sg:person.015650304144.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015650304144.58"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/00000421-198306000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002920977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-198306000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002920977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1979.251", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003197872", 
          "https://doi.org/10.1038/bjc.1979.251"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1979.251", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003197872", 
          "https://doi.org/10.1038/bjc.1979.251"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jso.2930230109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004901648"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19830815)52:4<610::aid-cncr2820520406>3.0.co;2-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009910727"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011360956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197811)42:5<2182::aid-cncr2820420515>3.0.co;2-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011497743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014257454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-2964(77)90196-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016233259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-198005000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016929254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-198005000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016929254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-198005000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016929254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-4731(81)90275-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017928234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-4731(81)90275-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017928234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800700405", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021872960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197708)40:2<937::aid-cncr2820400252>3.0.co;2-d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022288012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800730925", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027544360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm197611252952207", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030853219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197405)33:5<1246::aid-cncr2820330509>3.0.co;2-o", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035055033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197805)41:5<1685::aid-cncr2820410507>3.0.co;2-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036288482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00361858", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038443137", 
          "https://doi.org/10.1007/bf00361858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4612-5808-7_11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041413984", 
          "https://doi.org/10.1007/978-1-4612-5808-7_11"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jcp.37.9.1027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043795291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(84)90995-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047356072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197706)39:6<2397::aid-cncr2820390614>3.0.co;2-n", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050883291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2008-1069606", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057560963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/51.4.1119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080564200"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081614111", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082162983", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082258981", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1990-01", 
    "datePublishedReg": "1990-01-01", 
    "description": "A series of tumour related markers have been examined in 179 patients receiving primary endocrine therapy for metastatic breast cancer. Significant correlations between therapeutic response (UICC criteria after 6 months of treatment) and appropriate alterations in serum concentrations of carcinoembryonic antigen, ferritin, c-reactive protein, orosomucoid and the erythrocyte sedimentation rate, have been observed when changes in these markers were examined only at high serum concentrations. By combining these five markers a 'therapeutic index' of response has been devised which can be employed at an early stage of treatment in more than 90% of patients, giving an overall sensitivity/specificity of 90%/78% for therapeutic response or disease stabilisation over a 6-month period. The design of an objective measurement of response, which is easy to perform, has the potential to replace the existing, largely subjective. UICC criteria for retrospective judgement of response, and may also be used to direct systemic endocrine therapy.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/bjc.1990.26", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1017082", 
        "issn": [
          "0007-0920", 
          "1532-1827"
        ], 
        "name": "British Journal of Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "61"
      }
    ], 
    "name": "An objective biochemical assessment of therapeutic response in metastatic breast cancer: a study with external review of clinical data", 
    "pagination": "126", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8eb56949b39c0d3392c82460e776e6166f789f8ad95a2eae01a0c13628c3af50"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "2137007"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0370635"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/bjc.1990.26"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1029956355"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/bjc.1990.26", 
      "https://app.dimensions.ai/details/publication/pub.1029956355"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:55", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000359_0000000359/records_29212_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/bjc199026"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/bjc.1990.26'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/bjc.1990.26'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/bjc.1990.26'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/bjc.1990.26'


 

This table displays all metadata directly associated to this object as RDF triples.

239 TRIPLES      21 PREDICATES      72 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/bjc.1990.26 schema:about N0baa04f8dbf84dc19ebdc9ed0ba1727a
2 N30e970f662454b1e9fb1dc5389962822
3 N3d6e0a3f5546402dbca59ea9bd0f756d
4 N449182102a9e46799d3bc21ab944df68
5 N495f6ad1c59347eea90d28d7394b626c
6 N564f17ce80664f80af5ccb7b36895416
7 N64129b2179a6456bbf885ef57d500cb6
8 N759d6ba660b64028a76a268e920f63a6
9 N8063ec680f61466487b83bf459452538
10 N993c7dfd6e2a486b85e7cd640dc15746
11 Na04bfb6bfc264c71800322a23de75c15
12 Nae85a76de28248bb94be4dda3b235563
13 Nb6870217c2f54b76a17a52245c181113
14 Ncfc3741bfce44b5b94f57717c88dcb4f
15 Ne84bea80d1a94aca8a943a9731222000
16 Neb9989d032614751bb3c66417a5d0c56
17 Nfe49d62a0e034b08939a9716cb9b139e
18 anzsrc-for:11
19 anzsrc-for:1112
20 schema:author N806aa1023ab84397960008cd66d1052e
21 schema:citation sg:pub.10.1007/978-1-4612-5808-7_11
22 sg:pub.10.1007/bf00361858
23 sg:pub.10.1038/bjc.1979.251
24 https://app.dimensions.ai/details/publication/pub.1081614111
25 https://app.dimensions.ai/details/publication/pub.1082162983
26 https://app.dimensions.ai/details/publication/pub.1082258981
27 https://doi.org/10.1002/1097-0142(197405)33:5<1246::aid-cncr2820330509>3.0.co;2-o
28 https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f
29 https://doi.org/10.1002/1097-0142(197706)39:6<2397::aid-cncr2820390614>3.0.co;2-n
30 https://doi.org/10.1002/1097-0142(197708)40:2<937::aid-cncr2820400252>3.0.co;2-d
31 https://doi.org/10.1002/1097-0142(197805)41:5<1685::aid-cncr2820410507>3.0.co;2-9
32 https://doi.org/10.1002/1097-0142(197811)42:5<2182::aid-cncr2820420515>3.0.co;2-7
33 https://doi.org/10.1002/1097-0142(19830815)52:4<610::aid-cncr2820520406>3.0.co;2-5
34 https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u
35 https://doi.org/10.1002/bjs.1800700405
36 https://doi.org/10.1002/bjs.1800730925
37 https://doi.org/10.1002/jso.2930230109
38 https://doi.org/10.1016/0014-2964(77)90196-7
39 https://doi.org/10.1016/0022-4731(81)90275-2
40 https://doi.org/10.1016/s0140-6736(84)90995-4
41 https://doi.org/10.1055/s-2008-1069606
42 https://doi.org/10.1056/nejm197611252952207
43 https://doi.org/10.1093/jnci/51.4.1119
44 https://doi.org/10.1097/00000421-198306000-00006
45 https://doi.org/10.1097/00000658-198005000-00012
46 https://doi.org/10.1136/jcp.37.9.1027
47 schema:datePublished 1990-01
48 schema:datePublishedReg 1990-01-01
49 schema:description A series of tumour related markers have been examined in 179 patients receiving primary endocrine therapy for metastatic breast cancer. Significant correlations between therapeutic response (UICC criteria after 6 months of treatment) and appropriate alterations in serum concentrations of carcinoembryonic antigen, ferritin, c-reactive protein, orosomucoid and the erythrocyte sedimentation rate, have been observed when changes in these markers were examined only at high serum concentrations. By combining these five markers a 'therapeutic index' of response has been devised which can be employed at an early stage of treatment in more than 90% of patients, giving an overall sensitivity/specificity of 90%/78% for therapeutic response or disease stabilisation over a 6-month period. The design of an objective measurement of response, which is easy to perform, has the potential to replace the existing, largely subjective. UICC criteria for retrospective judgement of response, and may also be used to direct systemic endocrine therapy.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf N4dea91c9bc8242a4a387626f5ef562a4
54 N7a3b1e840aa54af4b507b31b640d5c95
55 sg:journal.1017082
56 schema:name An objective biochemical assessment of therapeutic response in metastatic breast cancer: a study with external review of clinical data
57 schema:pagination 126
58 schema:productId N32b0f12a72754ad3935e06c1b1cc1953
59 N8e79052a779b44e19f5b9eb6f3e17c96
60 Ndaa218fc652f42e4b88ee1c742c3b2c9
61 Ne65c0667446e4f1381919ee73f2ae97c
62 Nf8c6e65de7d4422ba04000cdece6df02
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029956355
64 https://doi.org/10.1038/bjc.1990.26
65 schema:sdDatePublished 2019-04-11T11:55
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher Nf4b1782526674ca488a26ce072885509
68 schema:url https://www.nature.com/articles/bjc199026
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N0baa04f8dbf84dc19ebdc9ed0ba1727a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Ovariectomy
74 rdf:type schema:DefinedTerm
75 N0e26ffc4a7304d0c98689869395afcc1 rdf:first sg:person.01204571037.12
76 rdf:rest Nfc76a9212cd046aba40bbbf2ce91d807
77 N223a6a1b740d49b7bbb71b45282a3bed rdf:first sg:person.01112542605.67
78 rdf:rest N2d82f412dca1403b808ae710c4e33755
79 N2d82f412dca1403b808ae710c4e33755 rdf:first sg:person.015650304144.58
80 rdf:rest rdf:nil
81 N30e970f662454b1e9fb1dc5389962822 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Blood Sedimentation
83 rdf:type schema:DefinedTerm
84 N32b0f12a72754ad3935e06c1b1cc1953 schema:name doi
85 schema:value 10.1038/bjc.1990.26
86 rdf:type schema:PropertyValue
87 N3d6e0a3f5546402dbca59ea9bd0f756d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Breast Neoplasms
89 rdf:type schema:DefinedTerm
90 N449182102a9e46799d3bc21ab944df68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Goserelin
92 rdf:type schema:DefinedTerm
93 N495f6ad1c59347eea90d28d7394b626c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Bone Neoplasms
95 rdf:type schema:DefinedTerm
96 N4dea91c9bc8242a4a387626f5ef562a4 schema:volumeNumber 61
97 rdf:type schema:PublicationVolume
98 N564f17ce80664f80af5ccb7b36895416 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Ferritins
100 rdf:type schema:DefinedTerm
101 N64129b2179a6456bbf885ef57d500cb6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name C-Reactive Protein
103 rdf:type schema:DefinedTerm
104 N759d6ba660b64028a76a268e920f63a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Tamoxifen
106 rdf:type schema:DefinedTerm
107 N7a3b1e840aa54af4b507b31b640d5c95 schema:issueNumber 1
108 rdf:type schema:PublicationIssue
109 N8063ec680f61466487b83bf459452538 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Orosomucoid
111 rdf:type schema:DefinedTerm
112 N806aa1023ab84397960008cd66d1052e rdf:first sg:person.0747422207.13
113 rdf:rest N0e26ffc4a7304d0c98689869395afcc1
114 N8e79052a779b44e19f5b9eb6f3e17c96 schema:name dimensions_id
115 schema:value pub.1029956355
116 rdf:type schema:PropertyValue
117 N993c7dfd6e2a486b85e7cd640dc15746 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Humans
119 rdf:type schema:DefinedTerm
120 Na04bfb6bfc264c71800322a23de75c15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Megestrol
122 rdf:type schema:DefinedTerm
123 Nae85a76de28248bb94be4dda3b235563 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Lung Neoplasms
125 rdf:type schema:DefinedTerm
126 Nb6870217c2f54b76a17a52245c181113 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Biomarkers, Tumor
128 rdf:type schema:DefinedTerm
129 Ncfc3741bfce44b5b94f57717c88dcb4f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Megestrol Acetate
131 rdf:type schema:DefinedTerm
132 Ndaa218fc652f42e4b88ee1c742c3b2c9 schema:name readcube_id
133 schema:value 8eb56949b39c0d3392c82460e776e6166f789f8ad95a2eae01a0c13628c3af50
134 rdf:type schema:PropertyValue
135 Ne65c0667446e4f1381919ee73f2ae97c schema:name nlm_unique_id
136 schema:value 0370635
137 rdf:type schema:PropertyValue
138 Ne84bea80d1a94aca8a943a9731222000 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Female
140 rdf:type schema:DefinedTerm
141 Neb9989d032614751bb3c66417a5d0c56 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Buserelin
143 rdf:type schema:DefinedTerm
144 Nf4b1782526674ca488a26ce072885509 schema:name Springer Nature - SN SciGraph project
145 rdf:type schema:Organization
146 Nf8c6e65de7d4422ba04000cdece6df02 schema:name pubmed_id
147 schema:value 2137007
148 rdf:type schema:PropertyValue
149 Nfc76a9212cd046aba40bbbf2ce91d807 rdf:first sg:person.01107407472.00
150 rdf:rest N223a6a1b740d49b7bbb71b45282a3bed
151 Nfe49d62a0e034b08939a9716cb9b139e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Carcinoembryonic Antigen
153 rdf:type schema:DefinedTerm
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
158 schema:name Oncology and Carcinogenesis
159 rdf:type schema:DefinedTerm
160 sg:journal.1017082 schema:issn 0007-0920
161 1532-1827
162 schema:name British Journal of Cancer
163 rdf:type schema:Periodical
164 sg:person.01107407472.00 schema:familyName Pearson
165 schema:givenName D
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107407472.00
167 rdf:type schema:Person
168 sg:person.01112542605.67 schema:familyName Griffiths
169 schema:givenName K
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112542605.67
171 rdf:type schema:Person
172 sg:person.01204571037.12 schema:familyName Turkes
173 schema:givenName A
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204571037.12
175 rdf:type schema:Person
176 sg:person.015650304144.58 schema:familyName Blamey
177 schema:givenName R W
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015650304144.58
179 rdf:type schema:Person
180 sg:person.0747422207.13 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
181 schema:familyName Williams
182 schema:givenName M R
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747422207.13
184 rdf:type schema:Person
185 sg:pub.10.1007/978-1-4612-5808-7_11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041413984
186 https://doi.org/10.1007/978-1-4612-5808-7_11
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/bf00361858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038443137
189 https://doi.org/10.1007/bf00361858
190 rdf:type schema:CreativeWork
191 sg:pub.10.1038/bjc.1979.251 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003197872
192 https://doi.org/10.1038/bjc.1979.251
193 rdf:type schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1081614111 schema:CreativeWork
195 https://app.dimensions.ai/details/publication/pub.1082162983 schema:CreativeWork
196 https://app.dimensions.ai/details/publication/pub.1082258981 schema:CreativeWork
197 https://doi.org/10.1002/1097-0142(197405)33:5<1246::aid-cncr2820330509>3.0.co;2-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1035055033
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1011360956
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1002/1097-0142(197706)39:6<2397::aid-cncr2820390614>3.0.co;2-n schema:sameAs https://app.dimensions.ai/details/publication/pub.1050883291
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1002/1097-0142(197708)40:2<937::aid-cncr2820400252>3.0.co;2-d schema:sameAs https://app.dimensions.ai/details/publication/pub.1022288012
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1002/1097-0142(197805)41:5<1685::aid-cncr2820410507>3.0.co;2-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036288482
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1002/1097-0142(197811)42:5<2182::aid-cncr2820420515>3.0.co;2-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011497743
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1002/1097-0142(19830815)52:4<610::aid-cncr2820520406>3.0.co;2-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009910727
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1014257454
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1002/bjs.1800700405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021872960
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1002/bjs.1800730925 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027544360
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1002/jso.2930230109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004901648
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/0014-2964(77)90196-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016233259
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/0022-4731(81)90275-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017928234
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/s0140-6736(84)90995-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047356072
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1055/s-2008-1069606 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057560963
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1056/nejm197611252952207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030853219
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1093/jnci/51.4.1119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080564200
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1097/00000421-198306000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002920977
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1097/00000658-198005000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016929254
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1136/jcp.37.9.1027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043795291
236 rdf:type schema:CreativeWork
237 https://www.grid.ac/institutes/grid.412920.c schema:alternateName Nottingham City Hospital
238 schema:name Nottingham City Hospital, UK.
239 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...