Fatty acid control of growth of human cervical and endometrial cancer cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1990-04

AUTHORS

R P Gleeson, M Ayub, J T Wright, C B Wood, N A Habib, W P Soutter, M H Sullivan, J O White

ABSTRACT

Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity. More... »

PAGES

bjc1990113

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bjc.1990.113

DOI

http://dx.doi.org/10.1038/bjc.1990.113

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011353938

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2331435


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