The use of an LH-RH agonist (ICI 118630, Zoladex) in advanced premenopausal breast cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1986-05

AUTHORS

M R Williams, K J Walker, A Turkes, R W Blamey, R I Nicholson

ABSTRACT

Fifty-three premenopausal patients presenting with advanced breast cancer have been treated with a potent new luteinising hormone-releasing hormone agonist Zoladex (ICI 118630) in a phase I clinical trial. On progression of disease 26 patients have undergone therapeutic oophorectomy. We present the clinical and endocrinological responses to treatment in 45 assessable patients. The response rate to Zoladex in this series was 31% and the ER status of the primary tumour was predictive of a response to the luteinising hormone-releasing hormone. More... »

PAGES

bjc1986106

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bjc.1986.106

DOI

http://dx.doi.org/10.1038/bjc.1986.106

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019490348

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2941044


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