Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1977-01

AUTHORS

R Peto, M C Pike, P Armitage, N E Breslow, D R Cox, S V Howard, N Mantel, K McPherson, J Peto, P G Smith

ABSTRACT

Part I of this report appeared in the previous issue (Br. J. Cancer (1976) 34,585), and discussed the design of randomized clinical trials. Part II now describes efficient methods of analysis of randomized clinical trials in which we wish to compare the duration of survival (or the time until some other untoward event first occurs) among different groups of patients. It is intended to enable physicians without statistical training either to analyse such data themselves using life tables, the logrank test and retrospective stratification, or, when such analyses are presented, to appreciate them more critically, but the discussion may also be of interest to statisticians who have not yet specialized in clinical trial analyses. More... »

PAGES

1-39

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/bjc.1977.1

DOI

http://dx.doi.org/10.1038/bjc.1977.1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027080276

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/831755


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