Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-04-11

AUTHORS

Qiaoling Liu, Chen Jin, Yanyue Wang, Xiaohong Fang, Xiaobing Zhang, Zhuo Chen, Weihong Tan

ABSTRACT

Based on their unique advantages, increasing interest has been shown in the use of aptamers as target ligands for specific cancer cell recognition and targeted cancer therapy. Recently, the development of aptamer-conjugated nanomaterials has offered new therapeutic opportunities for cancer treatment with better efficacy and lower toxicity. We highlight some of the promising classes of aptamer-conjugated nanomaterials for the specific recognition of cancer cells and targeted cancer therapy. Recent developments in the use of novel strategies that enable sensitive and selective cancer cell recognition are introduced. In addition to targeted drug delivery for chemotherapy, we also review how aptamer-conjugated nanomaterials are being incorporated into emerging technologies with significant improvement in efficiency and selectivity in cancer treatment. More... »

PAGES

e95-e95

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/am.2014.12

DOI

http://dx.doi.org/10.1038/am.2014.12

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https://app.dimensions.ai/details/publication/pub.1011006201

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29619132


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186 schema:name Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, Changsha, China
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