Impact of Chromoscopy on Adenoma Detection in Patients With Lynch Syndrome: A Prospective, Multicenter, Blinded, Tandem Colonoscopy Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-02

AUTHORS

Gabriel Rahmi, Thierry Lecomte, David Malka, Thibault Maniere, Marc Le Rhun, Rosine Guimbaud, Marie-Georges Lapalus, Anne Le Sidaner, Driffa Moussata, Olivier Caron, Jean-Pierre Barbieux, Marianne Gaudric, Emmanuel Coron, Karl Barange, Thierry Ponchon, Denis Sautereau, Elia Samaha, Jean-Christophe Saurin, Stanislas Chaussade, Pierre Laurent-Puig, Gilles Chatellier, Christophe Cellier

ABSTRACT

OBJECTIVES: In Lynch syndrome, flat and diminutive adenomas are particularly prone to malignant transformation, but they can be missed by standard colonoscopy. It is not known whether chromocolonoscopy is able to detect more adenomas than standard colonoscopy in patients with Lynch syndrome. METHODS: We conducted a prospective, multicenter, randomized trial to compare standard colonoscopy with standard colonoscopy followed by pancolonic chromoscopy with indigo carmine in patients with a proven germline mutation in a mismatch-repair gene related to Lynch syndrome and who were undergoing screening or surveillance colonoscopy. Standard colonoscopy was used first to detect visible lesions. Colonoscopy with chromoscopy was then performed by a second gastroenterologist (blinded to the findings of the first colonoscopy) to detect additional lesions. The primary end point was the number of patients in whom at least one adenoma was detected. RESULTS: A total of 78 eligible patients (median age, 45 years) were enrolled at 10 centers from July 2008 to August 2009. Significantly more patients with at least one adenoma were identified by chromocolonoscopy (32/78 (41%)) than by standard colonoscopy (18/78 (23%); P<0.001). The percentage of patients in whom at least one additional adenoma was detected during the chromoscopy was 31% (24/78). Overall, chromocolonoscopy plus colonoscopy detected a total of 55 adenomas in 32 patients (mean number of adenomas detected per patient: 0.7 vs. standard colonoscopy alone: 0.3; P<0.001). CONCLUSION: The results support the proposition that chromocolonoscopy may significantly improve the detection rate of colorectal adenomas in patients undergoing screening or surveillance colonoscopy for Lynch syndrome. More... »

PAGES

288

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ajg.2014.423

DOI

http://dx.doi.org/10.1038/ajg.2014.423

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039230642

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25601014


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colon", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colonoscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms, Hereditary Nonpolyposis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coloring Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Early Detection of Cancer", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indigo Carmine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rectum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Single-Blind Method", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rahmi", 
        "givenName": "Gabriel", 
        "id": "sg:person.0712633225.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712633225.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Tours", 
          "id": "https://www.grid.ac/institutes/grid.411167.4", 
          "name": [
            "Universit\u00e9 Fran\u00e7ois-Rabelais, Paris, France", 
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie et de Canc\u00e9rologie digestive, CHRU de Tours, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lecomte", 
        "givenName": "Thierry", 
        "id": "sg:person.01143615757.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143615757.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "D\u00e9partement de M\u00e9decine Oncologique, Unit\u00e9 d\u2019oncologie digestive, Institut Gustave Roussy, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Malka", 
        "givenName": "David", 
        "id": "sg:person.01030003625.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030003625.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maniere", 
        "givenName": "Thibault", 
        "id": "sg:person.01311000146.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311000146.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nantes", 
          "id": "https://www.grid.ac/institutes/grid.277151.7", 
          "name": [
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie, CHU de Nantes, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le Rhun", 
        "givenName": "Marc", 
        "id": "sg:person.01113775334.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113775334.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.11417.32", 
          "name": [
            "Service d\u2019oncologie, H\u00f4pital Purpan, Toulouse, France", 
            "Universit\u00e9 de Toulouse 3 University, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guimbaud", 
        "givenName": "Rosine", 
        "id": "sg:person.0750667273.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750667273.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital \u00c9douard-Herriot", 
          "id": "https://www.grid.ac/institutes/grid.412180.e", 
          "name": [
            "F\u00e9d\u00e9ration des Sp\u00e9cialit\u00e9s Digestives, H\u00f4pital Edouard Herriot, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lapalus", 
        "givenName": "Marie-Georges", 
        "id": "sg:person.01220624633.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220624633.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Universitaire Dupuytren", 
          "id": "https://www.grid.ac/institutes/grid.412212.6", 
          "name": [
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie, CHU Dupuytren, Limoges, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le Sidaner", 
        "givenName": "Anne", 
        "id": "sg:person.0775144626.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775144626.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Lyon Sud", 
          "id": "https://www.grid.ac/institutes/grid.411430.3", 
          "name": [
            "Service de Gastroent\u00e9rologie, H\u00f4pital Lyon Sud, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moussata", 
        "givenName": "Driffa", 
        "id": "sg:person.01072350333.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072350333.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Service d\u2019oncog\u00e9n\u00e9tique, Institut Gustave Roussy, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Caron", 
        "givenName": "Olivier", 
        "id": "sg:person.0710070200.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710070200.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Tours", 
          "id": "https://www.grid.ac/institutes/grid.411167.4", 
          "name": [
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie et de Canc\u00e9rologie digestive, CHRU de Tours, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barbieux", 
        "givenName": "Jean-Pierre", 
        "id": "sg:person.0620776176.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620776176.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Cochin", 
          "id": "https://www.grid.ac/institutes/grid.411784.f", 
          "name": [
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Cochin, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gaudric", 
        "givenName": "Marianne", 
        "id": "sg:person.0614507153.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614507153.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nantes", 
          "id": "https://www.grid.ac/institutes/grid.277151.7", 
          "name": [
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie, CHU de Nantes, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coron", 
        "givenName": "Emmanuel", 
        "id": "sg:person.01262617543.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262617543.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Purpan", 
          "id": "https://www.grid.ac/institutes/grid.414282.9", 
          "name": [
            "Service d'H\u00e9pato-gastroent\u00e9rologie, H\u00f4pital Purpan, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barange", 
        "givenName": "Karl", 
        "id": "sg:person.0742236160.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742236160.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital \u00c9douard-Herriot", 
          "id": "https://www.grid.ac/institutes/grid.412180.e", 
          "name": [
            "F\u00e9d\u00e9ration des Sp\u00e9cialit\u00e9s Digestives, H\u00f4pital Edouard Herriot, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ponchon", 
        "givenName": "Thierry", 
        "id": "sg:person.0713137561.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713137561.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Universitaire Dupuytren", 
          "id": "https://www.grid.ac/institutes/grid.412212.6", 
          "name": [
            "Service d\u2019H\u00e9pato-gastroent\u00e9rologie, CHU Dupuytren, Limoges, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sautereau", 
        "givenName": "Denis", 
        "id": "sg:person.01124674270.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124674270.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Samaha", 
        "givenName": "Elia", 
        "id": "sg:person.01105177062.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105177062.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Lyon Sud", 
          "id": "https://www.grid.ac/institutes/grid.411430.3", 
          "name": [
            "Service de Gastroent\u00e9rologie, H\u00f4pital Lyon Sud, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saurin", 
        "givenName": "Jean-Christophe", 
        "id": "sg:person.01076514673.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076514673.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Cochin", 
          "id": "https://www.grid.ac/institutes/grid.411784.f", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Cochin, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chaussade", 
        "givenName": "Stanislas", 
        "id": "sg:person.01352122365.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352122365.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Unit\u00e9 d\u2019oncog\u00e9n\u00e9tique, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Laurent-Puig", 
        "givenName": "Pierre", 
        "id": "sg:person.01021346341.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021346341.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Unit\u00e9 d\u2019\u00e9pid\u00e9miologie et de recherche clinique, H\u00f4pital europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chatellier", 
        "givenName": "Gilles", 
        "id": "sg:person.0610327425.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610327425.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Universit\u00e9 Paris Descartes, Paris, France; Paris Sorbonne Cit\u00e9, Paris, France", 
            "Assistance Publique des H\u00f4pitaux de Paris, Service de Gastroent\u00e9rologie, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cellier", 
        "givenName": "Christophe", 
        "id": "sg:person.0646114471.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646114471.00"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.cgh.2009.12.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005494811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02469505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007024979", 
          "https://doi.org/10.1007/bf02469505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2005.41481.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007032224", 
          "https://doi.org/10.1111/j.1572-0241.2005.41481.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2005.41481.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007032224", 
          "https://doi.org/10.1111/j.1572-0241.2005.41481.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2006.03.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008047834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2010.120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008693613", 
          "https://doi.org/10.1038/ajg.2010.120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2010.120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008693613", 
          "https://doi.org/10.1038/ajg.2010.120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gie.2007.05.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010223219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2007.128926", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011740152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.23.7784", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014351293"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-0004.2008.01035.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014533851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1542-3565(05)00403-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015548185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2006.00390.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016915146", 
          "https://doi.org/10.1111/j.1572-0241.2006.00390.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2006.00390.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016915146", 
          "https://doi.org/10.1111/j.1572-0241.2006.00390.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2003.029868", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017200521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1940-6207.capr-08-0096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018780370"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1940-6207.capr-08-0098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019154514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.296.12.1507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019575764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(90)90323-s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020551378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/gast.1996.v110.pm8612988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021087329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5085(97)70214-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021317691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ssu.2980110607", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021812203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncponc0248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022774609", 
          "https://doi.org/10.1038/ncponc0248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncponc0248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022774609", 
          "https://doi.org/10.1038/ncponc0248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncponc0248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022774609", 
          "https://doi.org/10.1038/ncponc0248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2011.743", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023653811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5107(02)70034-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027566148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5107(02)70034-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027566148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2010.229534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030119497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2007.08.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031382674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmg.2007.048991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033601684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.52.8.1140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038999172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2005.05.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040390083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5085(00)70168-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040475844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.50.2.228", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043467728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2009.07.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043552607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cgh.2009.10.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043953477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2007.13.2795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044416609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(95)91016-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046740712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(95)91016-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046740712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa055498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048137196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(00)02086-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051434998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.47.2.251", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053264246"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0950-3528(89)90021-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053629094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gastro.2005.05.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054735469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0028-1119628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057134971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/82.22.1769", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059816159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2000.18.11.2193", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074645666"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-02", 
    "datePublishedReg": "2015-02-01", 
    "description": "OBJECTIVES: In Lynch syndrome, flat and diminutive adenomas are particularly prone to malignant transformation, but they can be missed by standard colonoscopy. It is not known whether chromocolonoscopy is able to detect more adenomas than standard colonoscopy in patients with Lynch syndrome.\nMETHODS: We conducted a prospective, multicenter, randomized trial to compare standard colonoscopy with standard colonoscopy followed by pancolonic chromoscopy with indigo carmine in patients with a proven germline mutation in a mismatch-repair gene related to Lynch syndrome and who were undergoing screening or surveillance colonoscopy. Standard colonoscopy was used first to detect visible lesions. Colonoscopy with chromoscopy was then performed by a second gastroenterologist (blinded to the findings of the first colonoscopy) to detect additional lesions. The primary end point was the number of patients in whom at least one adenoma was detected.\nRESULTS: A total of 78 eligible patients (median age, 45 years) were enrolled at 10 centers from July 2008 to August 2009. Significantly more patients with at least one adenoma were identified by chromocolonoscopy (32/78 (41%)) than by standard colonoscopy (18/78 (23%); P<0.001). The percentage of patients in whom at least one additional adenoma was detected during the chromoscopy was 31% (24/78). Overall, chromocolonoscopy plus colonoscopy detected a total of 55 adenomas in 32 patients (mean number of adenomas detected per patient: 0.7 vs. standard colonoscopy alone: 0.3; P<0.001).\nCONCLUSION: The results support the proposition that chromocolonoscopy may significantly improve the detection rate of colorectal adenomas in patients undergoing screening or surveillance colonoscopy for Lynch syndrome.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ajg.2014.423", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019809", 
        "issn": [
          "0002-9270", 
          "1572-0241"
        ], 
        "name": "The American Journal of Gastroenterology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "110"
      }
    ], 
    "name": "Impact of Chromoscopy on Adenoma Detection in Patients With Lynch Syndrome: A Prospective, Multicenter, Blinded, Tandem Colonoscopy Study", 
    "pagination": "288", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "badf8bd0394af23b272a38358f580ee21ae442c6d4458909525868ff440987f5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25601014"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0421030"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ajg.2014.423"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039230642"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ajg.2014.423", 
      "https://app.dimensions.ai/details/publication/pub.1039230642"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000357_0000000357/records_99320_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/ajg2014423"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ajg.2014.423'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ajg.2014.423'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ajg.2014.423'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ajg.2014.423'


 

This table displays all metadata directly associated to this object as RDF triples.

442 TRIPLES      21 PREDICATES      86 URIs      37 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ajg.2014.423 schema:about N02f5c56402454488b6ac70ef7bce45f2
2 N094cc63a37134132aa6890d9e54e9ec6
3 N0a9f22accea847baab631d4685c0b24c
4 N24e3410a20eb436f8df1e13e1fca5af1
5 N2508e07f75b6450aa672626a48ca074a
6 N2ebfac9f24924af9ab9d0c063458d045
7 N4472884cc029405f9566444c67b0fc17
8 N4544792bce6b40f199e336e38eeb1103
9 N7a36117c9a024314b65be50a2421b8b5
10 N7cef4f54ce3d4181b85babb2f4c55657
11 N89ff5bd9f80f45e49a90a58404381038
12 N8a287431d61c40aca1ed2e439fc8d4de
13 N9d617145387940ffa8d62d279cfc5140
14 Nb9fcb6111b894bbea2a8177c9f0f1812
15 Nbb9614bdf8d5471394c0a0485faeb2e9
16 Nf39bca4f00854f77a75dac43764555e9
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author Nd1b7a56e716d40edb626b9578b25b3a6
20 schema:citation sg:pub.10.1007/bf02469505
21 sg:pub.10.1038/ajg.2010.120
22 sg:pub.10.1038/ncponc0248
23 sg:pub.10.1111/j.1572-0241.2005.41481.x
24 sg:pub.10.1111/j.1572-0241.2006.00390.x
25 https://doi.org/10.1001/jama.2011.743
26 https://doi.org/10.1001/jama.296.12.1507
27 https://doi.org/10.1002/ssu.2980110607
28 https://doi.org/10.1016/0016-5085(90)90323-s
29 https://doi.org/10.1016/0950-3528(89)90021-3
30 https://doi.org/10.1016/j.cgh.2009.10.003
31 https://doi.org/10.1016/j.cgh.2009.12.008
32 https://doi.org/10.1016/j.gastro.2005.05.011
33 https://doi.org/10.1016/j.gie.2007.05.029
34 https://doi.org/10.1016/s0016-5085(00)70168-5
35 https://doi.org/10.1016/s0016-5085(97)70214-2
36 https://doi.org/10.1016/s0016-5107(02)70034-5
37 https://doi.org/10.1016/s0140-6736(00)02086-9
38 https://doi.org/10.1016/s0140-6736(95)91016-6
39 https://doi.org/10.1016/s1542-3565(05)00403-9
40 https://doi.org/10.1053/gast.1996.v110.pm8612988
41 https://doi.org/10.1053/j.gastro.2005.05.011
42 https://doi.org/10.1053/j.gastro.2006.03.018
43 https://doi.org/10.1053/j.gastro.2007.08.019
44 https://doi.org/10.1053/j.gastro.2009.07.039
45 https://doi.org/10.1055/s-0028-1119628
46 https://doi.org/10.1056/nejmoa055498
47 https://doi.org/10.1093/jnci/82.22.1769
48 https://doi.org/10.1111/j.1399-0004.2008.01035.x
49 https://doi.org/10.1136/gut.2003.029868
50 https://doi.org/10.1136/gut.2007.128926
51 https://doi.org/10.1136/gut.2010.229534
52 https://doi.org/10.1136/gut.47.2.251
53 https://doi.org/10.1136/gut.50.2.228
54 https://doi.org/10.1136/gut.52.8.1140
55 https://doi.org/10.1136/jmg.2007.048991
56 https://doi.org/10.1158/1940-6207.capr-08-0096
57 https://doi.org/10.1158/1940-6207.capr-08-0098
58 https://doi.org/10.1200/jco.2000.18.11.2193
59 https://doi.org/10.1200/jco.2007.13.2795
60 https://doi.org/10.1200/jco.2009.23.7784
61 schema:datePublished 2015-02
62 schema:datePublishedReg 2015-02-01
63 schema:description OBJECTIVES: In Lynch syndrome, flat and diminutive adenomas are particularly prone to malignant transformation, but they can be missed by standard colonoscopy. It is not known whether chromocolonoscopy is able to detect more adenomas than standard colonoscopy in patients with Lynch syndrome. METHODS: We conducted a prospective, multicenter, randomized trial to compare standard colonoscopy with standard colonoscopy followed by pancolonic chromoscopy with indigo carmine in patients with a proven germline mutation in a mismatch-repair gene related to Lynch syndrome and who were undergoing screening or surveillance colonoscopy. Standard colonoscopy was used first to detect visible lesions. Colonoscopy with chromoscopy was then performed by a second gastroenterologist (blinded to the findings of the first colonoscopy) to detect additional lesions. The primary end point was the number of patients in whom at least one adenoma was detected. RESULTS: A total of 78 eligible patients (median age, 45 years) were enrolled at 10 centers from July 2008 to August 2009. Significantly more patients with at least one adenoma were identified by chromocolonoscopy (32/78 (41%)) than by standard colonoscopy (18/78 (23%); P<0.001). The percentage of patients in whom at least one additional adenoma was detected during the chromoscopy was 31% (24/78). Overall, chromocolonoscopy plus colonoscopy detected a total of 55 adenomas in 32 patients (mean number of adenomas detected per patient: 0.7 vs. standard colonoscopy alone: 0.3; P<0.001). CONCLUSION: The results support the proposition that chromocolonoscopy may significantly improve the detection rate of colorectal adenomas in patients undergoing screening or surveillance colonoscopy for Lynch syndrome.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree false
67 schema:isPartOf N2c94826575f64cdfb81e4e54c3396d0d
68 Nf6ff3a99ba254ea8a4b8ae778c11a856
69 sg:journal.1019809
70 schema:name Impact of Chromoscopy on Adenoma Detection in Patients With Lynch Syndrome: A Prospective, Multicenter, Blinded, Tandem Colonoscopy Study
71 schema:pagination 288
72 schema:productId N7cee276209394cb99ccca03c58166f3f
73 Na5bcda8ea10c4cb08a5c14527ed817ce
74 Nd643b3bbc7d342529a6dfff899a21f53
75 Nfa1e8646f7f44becab112ba76611ef03
76 Nfcb4dace45994f578ae334a7ed6ffb5e
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039230642
78 https://doi.org/10.1038/ajg.2014.423
79 schema:sdDatePublished 2019-04-11T11:31
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher Nbdab45b950194df2802baf0e4619be8f
82 schema:url https://www.nature.com/articles/ajg2014423
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N02f5c56402454488b6ac70ef7bce45f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Male
88 rdf:type schema:DefinedTerm
89 N032c38a4d9c14c439a73040415987a35 rdf:first sg:person.01021346341.79
90 rdf:rest Ndcc05cca3239401bb6e95e8b77ea6c80
91 N077487db415948f1a448cd6410881acb rdf:first sg:person.01105177062.10
92 rdf:rest N60b86e5c20c448aab387c3bc915aea2d
93 N094cc63a37134132aa6890d9e54e9ec6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Female
95 rdf:type schema:DefinedTerm
96 N0976529057c7463398fb6fdb56321f55 rdf:first sg:person.01124674270.94
97 rdf:rest N077487db415948f1a448cd6410881acb
98 N0a9f22accea847baab631d4685c0b24c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Colorectal Neoplasms, Hereditary Nonpolyposis
100 rdf:type schema:DefinedTerm
101 N0bc27ab4eaa44a32a878c7ed60164dc5 rdf:first sg:person.01352122365.10
102 rdf:rest N032c38a4d9c14c439a73040415987a35
103 N162b0278a9d84703b8570af918924a23 rdf:first sg:person.0710070200.11
104 rdf:rest N562cccf488be4bbd9efecb10a548a1d1
105 N24e3410a20eb436f8df1e13e1fca5af1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Middle Aged
107 rdf:type schema:DefinedTerm
108 N2508e07f75b6450aa672626a48ca074a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Coloring Agents
110 rdf:type schema:DefinedTerm
111 N2c94826575f64cdfb81e4e54c3396d0d schema:issueNumber 2
112 rdf:type schema:PublicationIssue
113 N2ebfac9f24924af9ab9d0c063458d045 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Early Detection of Cancer
115 rdf:type schema:DefinedTerm
116 N4050a043f16b4e0f8a7ee8b5a8ef4eff rdf:first sg:person.0614507153.52
117 rdf:rest Naad85930da284c758cf00b41078681a3
118 N4472884cc029405f9566444c67b0fc17 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Colon
120 rdf:type schema:DefinedTerm
121 N4544792bce6b40f199e336e38eeb1103 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Humans
123 rdf:type schema:DefinedTerm
124 N45877255f5c348c09042cba25874dc63 rdf:first sg:person.0775144626.51
125 rdf:rest N4d08cd4741d54b7fad08cec234c5feff
126 N4d08cd4741d54b7fad08cec234c5feff rdf:first sg:person.01072350333.41
127 rdf:rest N162b0278a9d84703b8570af918924a23
128 N4d3dbb3dea7d4fd8ba9652deb40c34b5 rdf:first sg:person.01113775334.59
129 rdf:rest Ne958522afd7c429c929afbf13285cb31
130 N53aff39018ef4c648a39c7dd2dbd077a rdf:first sg:person.01030003625.43
131 rdf:rest Ncbf302655a3a4ed183464464ac37cdc2
132 N562cccf488be4bbd9efecb10a548a1d1 rdf:first sg:person.0620776176.34
133 rdf:rest N4050a043f16b4e0f8a7ee8b5a8ef4eff
134 N60b86e5c20c448aab387c3bc915aea2d rdf:first sg:person.01076514673.63
135 rdf:rest N0bc27ab4eaa44a32a878c7ed60164dc5
136 N6634667eb75d4cc5a1cd263dcf6f1570 rdf:first sg:person.01143615757.53
137 rdf:rest N53aff39018ef4c648a39c7dd2dbd077a
138 N7a36117c9a024314b65be50a2421b8b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Rectum
140 rdf:type schema:DefinedTerm
141 N7cee276209394cb99ccca03c58166f3f schema:name doi
142 schema:value 10.1038/ajg.2014.423
143 rdf:type schema:PropertyValue
144 N7cef4f54ce3d4181b85babb2f4c55657 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Indigo Carmine
146 rdf:type schema:DefinedTerm
147 N89a66993a7ef4922967329ed85ed3538 rdf:first sg:person.0646114471.00
148 rdf:rest rdf:nil
149 N89ff5bd9f80f45e49a90a58404381038 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Adult
151 rdf:type schema:DefinedTerm
152 N8a287431d61c40aca1ed2e439fc8d4de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Carcinoma
154 rdf:type schema:DefinedTerm
155 N8d43b90f831b4d0a81812705d105727b rdf:first sg:person.0713137561.47
156 rdf:rest N0976529057c7463398fb6fdb56321f55
157 N9d617145387940ffa8d62d279cfc5140 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Single-Blind Method
159 rdf:type schema:DefinedTerm
160 Na5bcda8ea10c4cb08a5c14527ed817ce schema:name pubmed_id
161 schema:value 25601014
162 rdf:type schema:PropertyValue
163 Naa971957a9e542b8b75c0a15eee56296 rdf:first sg:person.0742236160.59
164 rdf:rest N8d43b90f831b4d0a81812705d105727b
165 Naad85930da284c758cf00b41078681a3 rdf:first sg:person.01262617543.38
166 rdf:rest Naa971957a9e542b8b75c0a15eee56296
167 Nb9fcb6111b894bbea2a8177c9f0f1812 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Colonoscopy
169 rdf:type schema:DefinedTerm
170 Nbb9614bdf8d5471394c0a0485faeb2e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Colorectal Neoplasms
172 rdf:type schema:DefinedTerm
173 Nbdab45b950194df2802baf0e4619be8f schema:name Springer Nature - SN SciGraph project
174 rdf:type schema:Organization
175 Ncbf302655a3a4ed183464464ac37cdc2 rdf:first sg:person.01311000146.55
176 rdf:rest N4d3dbb3dea7d4fd8ba9652deb40c34b5
177 Nd1b7a56e716d40edb626b9578b25b3a6 rdf:first sg:person.0712633225.57
178 rdf:rest N6634667eb75d4cc5a1cd263dcf6f1570
179 Nd643b3bbc7d342529a6dfff899a21f53 schema:name readcube_id
180 schema:value badf8bd0394af23b272a38358f580ee21ae442c6d4458909525868ff440987f5
181 rdf:type schema:PropertyValue
182 Ndcc05cca3239401bb6e95e8b77ea6c80 rdf:first sg:person.0610327425.04
183 rdf:rest N89a66993a7ef4922967329ed85ed3538
184 Ne958522afd7c429c929afbf13285cb31 rdf:first sg:person.0750667273.97
185 rdf:rest Nfccc2a2525ea47618cda000892464e8f
186 Nf39bca4f00854f77a75dac43764555e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Adenoma
188 rdf:type schema:DefinedTerm
189 Nf6ff3a99ba254ea8a4b8ae778c11a856 schema:volumeNumber 110
190 rdf:type schema:PublicationVolume
191 Nfa1e8646f7f44becab112ba76611ef03 schema:name dimensions_id
192 schema:value pub.1039230642
193 rdf:type schema:PropertyValue
194 Nfcb4dace45994f578ae334a7ed6ffb5e schema:name nlm_unique_id
195 schema:value 0421030
196 rdf:type schema:PropertyValue
197 Nfccc2a2525ea47618cda000892464e8f rdf:first sg:person.01220624633.24
198 rdf:rest N45877255f5c348c09042cba25874dc63
199 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
200 schema:name Medical and Health Sciences
201 rdf:type schema:DefinedTerm
202 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
203 schema:name Clinical Sciences
204 rdf:type schema:DefinedTerm
205 sg:journal.1019809 schema:issn 0002-9270
206 1572-0241
207 schema:name The American Journal of Gastroenterology
208 rdf:type schema:Periodical
209 sg:person.01021346341.79 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
210 schema:familyName Laurent-Puig
211 schema:givenName Pierre
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021346341.79
213 rdf:type schema:Person
214 sg:person.01030003625.43 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
215 schema:familyName Malka
216 schema:givenName David
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030003625.43
218 rdf:type schema:Person
219 sg:person.01072350333.41 schema:affiliation https://www.grid.ac/institutes/grid.411430.3
220 schema:familyName Moussata
221 schema:givenName Driffa
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072350333.41
223 rdf:type schema:Person
224 sg:person.01076514673.63 schema:affiliation https://www.grid.ac/institutes/grid.411430.3
225 schema:familyName Saurin
226 schema:givenName Jean-Christophe
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076514673.63
228 rdf:type schema:Person
229 sg:person.01105177062.10 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
230 schema:familyName Samaha
231 schema:givenName Elia
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105177062.10
233 rdf:type schema:Person
234 sg:person.01113775334.59 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
235 schema:familyName Le Rhun
236 schema:givenName Marc
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113775334.59
238 rdf:type schema:Person
239 sg:person.01124674270.94 schema:affiliation https://www.grid.ac/institutes/grid.412212.6
240 schema:familyName Sautereau
241 schema:givenName Denis
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124674270.94
243 rdf:type schema:Person
244 sg:person.01143615757.53 schema:affiliation https://www.grid.ac/institutes/grid.411167.4
245 schema:familyName Lecomte
246 schema:givenName Thierry
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143615757.53
248 rdf:type schema:Person
249 sg:person.01220624633.24 schema:affiliation https://www.grid.ac/institutes/grid.412180.e
250 schema:familyName Lapalus
251 schema:givenName Marie-Georges
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220624633.24
253 rdf:type schema:Person
254 sg:person.01262617543.38 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
255 schema:familyName Coron
256 schema:givenName Emmanuel
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262617543.38
258 rdf:type schema:Person
259 sg:person.01311000146.55 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
260 schema:familyName Maniere
261 schema:givenName Thibault
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311000146.55
263 rdf:type schema:Person
264 sg:person.01352122365.10 schema:affiliation https://www.grid.ac/institutes/grid.411784.f
265 schema:familyName Chaussade
266 schema:givenName Stanislas
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352122365.10
268 rdf:type schema:Person
269 sg:person.0610327425.04 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
270 schema:familyName Chatellier
271 schema:givenName Gilles
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610327425.04
273 rdf:type schema:Person
274 sg:person.0614507153.52 schema:affiliation https://www.grid.ac/institutes/grid.411784.f
275 schema:familyName Gaudric
276 schema:givenName Marianne
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614507153.52
278 rdf:type schema:Person
279 sg:person.0620776176.34 schema:affiliation https://www.grid.ac/institutes/grid.411167.4
280 schema:familyName Barbieux
281 schema:givenName Jean-Pierre
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620776176.34
283 rdf:type schema:Person
284 sg:person.0646114471.00 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
285 schema:familyName Cellier
286 schema:givenName Christophe
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646114471.00
288 rdf:type schema:Person
289 sg:person.0710070200.11 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
290 schema:familyName Caron
291 schema:givenName Olivier
292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710070200.11
293 rdf:type schema:Person
294 sg:person.0712633225.57 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
295 schema:familyName Rahmi
296 schema:givenName Gabriel
297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712633225.57
298 rdf:type schema:Person
299 sg:person.0713137561.47 schema:affiliation https://www.grid.ac/institutes/grid.412180.e
300 schema:familyName Ponchon
301 schema:givenName Thierry
302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713137561.47
303 rdf:type schema:Person
304 sg:person.0742236160.59 schema:affiliation https://www.grid.ac/institutes/grid.414282.9
305 schema:familyName Barange
306 schema:givenName Karl
307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742236160.59
308 rdf:type schema:Person
309 sg:person.0750667273.97 schema:affiliation https://www.grid.ac/institutes/grid.11417.32
310 schema:familyName Guimbaud
311 schema:givenName Rosine
312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750667273.97
313 rdf:type schema:Person
314 sg:person.0775144626.51 schema:affiliation https://www.grid.ac/institutes/grid.412212.6
315 schema:familyName Le Sidaner
316 schema:givenName Anne
317 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775144626.51
318 rdf:type schema:Person
319 sg:pub.10.1007/bf02469505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007024979
320 https://doi.org/10.1007/bf02469505
321 rdf:type schema:CreativeWork
322 sg:pub.10.1038/ajg.2010.120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008693613
323 https://doi.org/10.1038/ajg.2010.120
324 rdf:type schema:CreativeWork
325 sg:pub.10.1038/ncponc0248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022774609
326 https://doi.org/10.1038/ncponc0248
327 rdf:type schema:CreativeWork
328 sg:pub.10.1111/j.1572-0241.2005.41481.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007032224
329 https://doi.org/10.1111/j.1572-0241.2005.41481.x
330 rdf:type schema:CreativeWork
331 sg:pub.10.1111/j.1572-0241.2006.00390.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016915146
332 https://doi.org/10.1111/j.1572-0241.2006.00390.x
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1001/jama.2011.743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023653811
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1001/jama.296.12.1507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019575764
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1002/ssu.2980110607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021812203
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1016/0016-5085(90)90323-s schema:sameAs https://app.dimensions.ai/details/publication/pub.1020551378
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/0950-3528(89)90021-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053629094
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/j.cgh.2009.10.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043953477
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/j.cgh.2009.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005494811
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/j.gastro.2005.05.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054735469
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/j.gie.2007.05.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010223219
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1016/s0016-5085(00)70168-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040475844
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1016/s0016-5085(97)70214-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021317691
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1016/s0016-5107(02)70034-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027566148
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1016/s0140-6736(00)02086-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051434998
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1016/s0140-6736(95)91016-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046740712
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1016/s1542-3565(05)00403-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015548185
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1053/gast.1996.v110.pm8612988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021087329
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1053/j.gastro.2005.05.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040390083
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1053/j.gastro.2006.03.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008047834
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1053/j.gastro.2007.08.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031382674
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1053/j.gastro.2009.07.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043552607
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1055/s-0028-1119628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057134971
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1056/nejmoa055498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048137196
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1093/jnci/82.22.1769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059816159
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1111/j.1399-0004.2008.01035.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014533851
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1136/gut.2003.029868 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017200521
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1136/gut.2007.128926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011740152
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1136/gut.2010.229534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030119497
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1136/gut.47.2.251 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053264246
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1136/gut.50.2.228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043467728
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1136/gut.52.8.1140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038999172
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1136/jmg.2007.048991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033601684
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1158/1940-6207.capr-08-0096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018780370
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1158/1940-6207.capr-08-0098 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019154514
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1200/jco.2000.18.11.2193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074645666
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1200/jco.2007.13.2795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044416609
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1200/jco.2009.23.7784 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014351293
405 rdf:type schema:CreativeWork
406 https://www.grid.ac/institutes/grid.11417.32 schema:alternateName University of Toulouse
407 schema:name Service d’oncologie, Hôpital Purpan, Toulouse, France
408 Université de Toulouse 3 University, Toulouse, France
409 rdf:type schema:Organization
410 https://www.grid.ac/institutes/grid.14925.3b schema:alternateName Institut Gustave Roussy
411 schema:name Département de Médecine Oncologique, Unité d’oncologie digestive, Institut Gustave Roussy, Villejuif, France
412 Service d’oncogénétique, Institut Gustave Roussy, Villejuif, France
413 rdf:type schema:Organization
414 https://www.grid.ac/institutes/grid.277151.7 schema:alternateName Centre Hospitalier Universitaire de Nantes
415 schema:name Service d’Hépato-gastroentérologie, CHU de Nantes, Nantes, France
416 rdf:type schema:Organization
417 https://www.grid.ac/institutes/grid.411167.4 schema:alternateName Centre Hospitalier Universitaire de Tours
418 schema:name Service d’Hépato-gastroentérologie et de Cancérologie digestive, CHRU de Tours, Paris, France
419 Université François-Rabelais, Paris, France
420 rdf:type schema:Organization
421 https://www.grid.ac/institutes/grid.411430.3 schema:alternateName Centre Hospitalier Lyon Sud
422 schema:name Service de Gastroentérologie, Hôpital Lyon Sud, Lyon, France
423 rdf:type schema:Organization
424 https://www.grid.ac/institutes/grid.411784.f schema:alternateName Hôpital Cochin
425 schema:name Assistance Publique des Hôpitaux de Paris, Service de Gastroentérologie, Hôpital Cochin, Paris, France
426 Université Paris Descartes, Paris, France; Paris Sorbonne Cité, Paris, France
427 rdf:type schema:Organization
428 https://www.grid.ac/institutes/grid.412180.e schema:alternateName Hôpital Édouard-Herriot
429 schema:name Fédération des Spécialités Digestives, Hôpital Edouard Herriot, Lyon, France
430 rdf:type schema:Organization
431 https://www.grid.ac/institutes/grid.412212.6 schema:alternateName Hôpital Universitaire Dupuytren
432 schema:name Service d’Hépato-gastroentérologie, CHU Dupuytren, Limoges, France
433 rdf:type schema:Organization
434 https://www.grid.ac/institutes/grid.414093.b schema:alternateName Hôpital Européen Georges-Pompidou
435 schema:name Assistance Publique des Hôpitaux de Paris, Service de Gastroentérologie, Hôpital Européen Georges Pompidou, Paris, France
436 Assistance Publique des Hôpitaux de Paris, Unité d’oncogénétique, Hôpital Européen Georges Pompidou, Paris, France
437 Assistance Publique des Hôpitaux de Paris, Unité d’épidémiologie et de recherche clinique, Hôpital européen Georges Pompidou, Paris, France
438 Université Paris Descartes, Paris, France; Paris Sorbonne Cité, Paris, France
439 rdf:type schema:Organization
440 https://www.grid.ac/institutes/grid.414282.9 schema:alternateName Hôpital Purpan
441 schema:name Service d'Hépato-gastroentérologie, Hôpital Purpan, Toulouse, France
442 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...