Differences in Inflammatory Bowel Disease Phenotype between South Asians and Northern Europeans Living in North West London, UK View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-07

AUTHORS

David G Walker, Horace R T Williams, Stephen P Kane, Joel E Mawdsley, Jayantha Arnold, Ian McNeil, Huw J W Thomas, Julian P Teare, Ailsa L Hart, Maxton C L Pitcher, Julian R F Walters, Sara E Marshall, Timothy R Orchard

ABSTRACT

OBJECTIVES: The incidence and prevalence of inflammatory bowel disease (IBD) is increasing throughout Asia. Since the 1950s, there has been substantial migration from South Asia (India, Pakistan, and Bangladesh) to the United Kingdom. The aim of this study was to define the clinical phenotype of IBD in UK South Asians living in North West London, and to compare the results with a white Northern European IBD cohort. METHODS: The phenotypic details of 367 South Asian IBD patients (273 ulcerative colitis (UC) and 94 Crohn's disease (CD)), undergoing active follow-up in five North West London hospitals, were compared with those of 403 consecutively collected white Northern European IBD patients (188 UC and 215 CD). RESULTS: The phenotype of IBD differed significantly between the two populations. 63.0% of South Asian UC patients had extensive colitis compared with 42.5% of the Northern European cohort (P < 0.0001). Proctitis was uncommon in South Asian UC patients (9.9 vs. 26.1% in Northern European patients, P<0.0001). In the South Asian CD cohort, disease location was predominantly colonic (46.8%). CD behavior differed significantly between the groups, with less penetrating disease compared with Northern Europeans (P=0.01) and a reduced need for surgery (P=0.003). CONCLUSIONS: The phenotype of IBD in South Asians living in North West London is significantly different from that of a white Northern European IBD cohort. Knowledge of ethnic variations in disease phenotype may help to identify key genetic, environmental, and behavioral factors contributing to the development of IBD. More... »

PAGES

1281

References to SciGraph publications

  • 2007-06-07. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls in NATURE
  • 1999-10. The effects of migration on ulcerative colitis: a three-year prospective study among Europeans and first- and second-generation South Asians in Leicester (1991–1994) in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2008-08. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease in NATURE GENETICS
  • 2009-05. Crohn’s Disease in India: A Multicenter Study from a Country Where Tuberculosis Is Endemic in DIGESTIVE DISEASES AND SCIENCES
  • 2009-08. Distribution and Manifestations of Inflammatory Bowel Disease in Asians, Hispanics, and African Americans: A Systematic Review in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2007-02. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 in NATURE GENETICS
  • 2008-12. The effect of smoking after surgery for Crohn’s disease: a meta-analysis of observational studies in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2009-09. Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2004-09. Incidence of Inflammatory Bowel Disease is Rising and Abdominal Tuberculosis is Falling in Bangladeshis in East London, United Kingdom in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2008-01. Inflammatory Bowel Disease in the South Asian Population of Northwest England in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2007-11. The Role of Smoking in Crohn’s Disease as Defined by Clinical Variables in DIGESTIVE DISEASES AND SCIENCES
  • 1999-10. The effects of migration on ulcerative colitis: a three-year prospective study among Europeans and first- and second-generation South Asians in Leicester (1991–1994) in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2004-12. Differential Effects of NOD2 Variants on Crohn's Disease Risk and Phenotype in Diverse Populations: A Metaanalysis in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2003-02. Tobacco Consumption and Disease Duration Are Associated With Fistulizing and Stricturing Behaviors in the First 8 Years of Crohn's Disease in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ajg.2011.85

    DOI

    http://dx.doi.org/10.1038/ajg.2011.85

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1022465609

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21577243


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