NOD2 Mutations and Anti-Saccharomyces cerevisiae Antibodies Are Risk Factors for Crohn's Disease in African Americans View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-02

AUTHORS

Themistocles Dassopoulos, Geoffrey C Nguyen, Monica Vladut Talor, Lisa Wu Datta, Kim L Isaacs, James D Lewis, Michael S Gold, John F Valentine, Duane T Smoot, Mary L Harris, Maria Oliva-Hemker, Theodore M Bayless, C Lynne Burek, Steven R Brant

ABSTRACT

OBJECTIVES: NOD2 mutations and anti-Saccharomyces cerevisiae antibodies (ASCAs) are established risk factors of Crohn's disease (CD) in whites but have not been assessed in African-American (AA) adults with CD. METHODS: AAs with CD and controls were recruited by the Mid-Atlantic African-American IBD Study as part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium. Genotyping for the three common CD NOD2 mutations (Leu1007fsinsC, G908R/2722g>c, and R702W/2104c>t) and ASCA enzyme-linked immunosorbent assays were performed in 183 AA CD patients and in 143 controls. Logistic regression was used to calculate adjusted odds ratios (ORs) for the association between ASCA and disease phenotype. RESULTS: ASCA sensitivity and specificity values were 70.5 and 70.4%, respectively. On univariate analysis, ASCA was significantly associated with younger age at diagnosis, ileal involvement, and complicated (stricturing/penetrating) behavior. On multivariate analysis, ASCA titer (per 25 Units) was associated with ileal involvement (OR 1.18, 95% confidence interval (CI): 1.04-1.34), complicated behavior (OR 1.13, 95% CI: 1.01-1.28), and surgery (hazard ratio: 1.11, 95% CI: 1.02-1.21). Cigarette smoking and CD family history were also significantly associated with surgery. NOD2 carriers (all heterozygotes) were more common among CD cases than controls (8.2 vs. 2.1%; OR 4.17%, 95% CI: 1.18-14.69). The NOD2 mutation population attributable risk was 6.2%. CONCLUSIONS: In comparison with whites, ASCA in AAs has a similar sensitivity but a lower specificity for CD. ASCA is associated with ileal involvement, complicated behavior, and surgery in AAs with CD. NOD2 is a risk gene for AA CD, although mutation frequency and population attributable risk are much lower than in whites. More... »

PAGES

ajg2009575

References to SciGraph publications

  • 2008-02. Evolution of Crohn’s disease-associated Nod2 mutations in IMMUNOGENETICS
  • 2004-07. Optimising the diagnostic value of Anti-Saccharomyces cerevisiae-antibodies (ASCA) in Crohn’s disease in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2003-01. Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2007-06. Prevalence of CARD15/NOD2 Mutations in Caucasian Healthy People in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2001-05. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease in NATURE
  • 2001-03. Diagnostic value of anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2005-10. Impact of Race and Ethnicity on Inflammatory Bowel Disease in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2006-05. Inflammatory Bowel Disease Characteristics Among African Americans, Hispanics, and Non-Hispanic Whites: Characterization of a Large North American Cohort in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2001-05. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease in NATURE
  • 2004-11. A Prospective Comparative Study of ASCA and pANCA in Chinese and Caucasian IBD Patients in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2004-12. Differential Effects of NOD2 Variants on Crohn's Disease Risk and Phenotype in Diverse Populations: A Metaanalysis in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2007-02. A Population-Based Case-Control Study of CARD15 and Other Risk Factors in Crohn's Disease and Ulcerative Colitis in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2005-01. Variants of CARD15 are Associated with an Aggressive Clinical Course of Crohn's Disease—An IG-IBD Study in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ajg.2009.575

    DOI

    http://dx.doi.org/10.1038/ajg.2009.575

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1007845176

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19826411


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Historical Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/21", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "History and Archaeology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "African Americans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antibodies, Fungal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Case-Control Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Crohn Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mutation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Nod2 Signaling Adaptor Protein", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Saccharomyces cerevisiae", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sensitivity and Specificity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Young Adult", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dassopoulos", 
            "givenName": "Themistocles", 
            "id": "sg:person.016431435207.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016431435207.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Toronto", 
              "id": "https://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA", 
                "Mount Sinai Hospital IBD Centre, Department of Medicine, University of Toronto, Toronto, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nguyen", 
            "givenName": "Geoffrey C", 
            "id": "sg:person.01120330150.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120330150.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Talor", 
            "givenName": "Monica Vladut", 
            "id": "sg:person.01356355561.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356355561.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Datta", 
            "givenName": "Lisa Wu", 
            "id": "sg:person.0742437133.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742437133.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of North Carolina at Chapel Hill", 
              "id": "https://www.grid.ac/institutes/grid.10698.36", 
              "name": [
                "Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Isaacs", 
            "givenName": "Kim L", 
            "id": "sg:person.01121465153.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121465153.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Pennsylvania", 
              "id": "https://www.grid.ac/institutes/grid.25879.31", 
              "name": [
                "Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lewis", 
            "givenName": "James D", 
            "id": "sg:person.015262716107.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015262716107.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "MedStar Washington Hospital Center", 
              "id": "https://www.grid.ac/institutes/grid.415235.4", 
              "name": [
                "Department of Medicine, Washington Hospital Center, Washington, DC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gold", 
            "givenName": "Michael S", 
            "id": "sg:person.0731375235.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731375235.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Florida", 
              "id": "https://www.grid.ac/institutes/grid.15276.37", 
              "name": [
                "Department of Medicine, University of Florida, Gainesville, Florida, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Valentine", 
            "givenName": "John F", 
            "id": "sg:person.01007154501.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007154501.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Howard University", 
              "id": "https://www.grid.ac/institutes/grid.257127.4", 
              "name": [
                "Department of Medicine, Howard University, Washington, DC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Smoot", 
            "givenName": "Duane T", 
            "id": "sg:person.0771421401.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771421401.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Harris", 
            "givenName": "Mary L", 
            "id": "sg:person.01234556550.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234556550.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Oliva-Hemker", 
            "givenName": "Maria", 
            "id": "sg:person.01267614456.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267614456.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bayless", 
            "givenName": "Theodore M", 
            "id": "sg:person.01000502162.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000502162.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Burek", 
            "givenName": "C Lynne", 
            "id": "sg:person.07606672634.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07606672634.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA", 
                "Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brant", 
            "givenName": "Steven R", 
            "id": "sg:person.016644232277.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016644232277.39"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1111/j.1572-0241.2007.01149.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001274568", 
              "https://doi.org/10.1111/j.1572-0241.2007.01149.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/j.gastro.2003.11.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004273091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.47.4.487", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004745588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2006.00926.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006636141", 
              "https://doi.org/10.1111/j.1572-0241.2006.00926.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200812003-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006850847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200812003-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006850847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200812003-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006850847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.1996.v111.pm8780559", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006910829"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(02)08590-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010754431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.ejhg.5200897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011406469", 
              "https://doi.org/10.1038/sj.ejhg.5200897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.ejhg.5200897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011406469", 
              "https://doi.org/10.1038/sj.ejhg.5200897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.1996.v111.pm8780560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013203466"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2005.40705.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014780630", 
              "https://doi.org/10.1111/j.1572-0241.2005.40705.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2004.40486.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018047226", 
              "https://doi.org/10.1111/j.1572-0241.2004.40486.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.2005.082909", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018299078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200409000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018958470"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200409000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018958470"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mpg.0b013e3180335bb3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019360513"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mpg.0b013e3180335bb3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019360513"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200002000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021029359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200002000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021029359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-003-0557-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021587892", 
              "https://doi.org/10.1007/s00384-003-0557-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.2002.32413", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021871792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200309000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023060757"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200309000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023060757"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.2001.22546", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025520718"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2001.03613.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025593726", 
              "https://doi.org/10.1111/j.1572-0241.2001.03613.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/339432", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026249532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.2002.35393", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028345248"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2005/269076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028822302"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2004.40304.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028921167", 
              "https://doi.org/10.1111/j.1572-0241.2004.40304.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mib.0000217767.98389.20", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029470448"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mib.0000217767.98389.20", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029470448"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.2002.32415", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029624284"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35079114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030806509", 
              "https://doi.org/10.1038/35079114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35079114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030806509", 
              "https://doi.org/10.1038/35079114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00251-008-0274-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030964719", 
              "https://doi.org/10.1007/s00251-008-0274-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00251-008-0274-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030964719", 
              "https://doi.org/10.1007/s00251-008-0274-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35079107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031360950", 
              "https://doi.org/10.1038/35079107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35079107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031360950", 
              "https://doi.org/10.1038/35079107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0022-3476(98)70187-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032936191"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/341124", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032943926"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mcp.2005.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033405794"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mcp.2005.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033405794"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0002769", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033675407"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/gast.2002.34020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034708505"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034922102"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034922102"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200812001-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036740608"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200812001-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036740608"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200102000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036804048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00054725-200102000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036804048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2249.2003.02392.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037117711"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2005.00233.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040810353", 
              "https://doi.org/10.1111/j.1572-0241.2005.00233.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2005.00233.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040810353", 
              "https://doi.org/10.1111/j.1572-0241.2005.00233.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.42.6.788", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041111311"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mib.0000171279.05471.21", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042523868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mib.0000171279.05471.21", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042523868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mib.0000171279.05471.21", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042523868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1572-0241.2006.00504.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043121940", 
              "https://doi.org/10.1111/j.1572-0241.2006.00504.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043702842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043702842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045490322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045490322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0016-5085(92)90317-r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045551170"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20144", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046883242"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20144", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046883242"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.2003.030734", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047153015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.3780060103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049055320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1590-8658(01)80692-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051845687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.52.4.558", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051926100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077040877", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-02", 
        "datePublishedReg": "2010-02-01", 
        "description": "OBJECTIVES: NOD2 mutations and anti-Saccharomyces cerevisiae antibodies (ASCAs) are established risk factors of Crohn's disease (CD) in whites but have not been assessed in African-American (AA) adults with CD.\nMETHODS: AAs with CD and controls were recruited by the Mid-Atlantic African-American IBD Study as part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium. Genotyping for the three common CD NOD2 mutations (Leu1007fsinsC, G908R/2722g>c, and R702W/2104c>t) and ASCA enzyme-linked immunosorbent assays were performed in 183 AA CD patients and in 143 controls. Logistic regression was used to calculate adjusted odds ratios (ORs) for the association between ASCA and disease phenotype.\nRESULTS: ASCA sensitivity and specificity values were 70.5 and 70.4%, respectively. On univariate analysis, ASCA was significantly associated with younger age at diagnosis, ileal involvement, and complicated (stricturing/penetrating) behavior. On multivariate analysis, ASCA titer (per 25 Units) was associated with ileal involvement (OR 1.18, 95% confidence interval (CI): 1.04-1.34), complicated behavior (OR 1.13, 95% CI: 1.01-1.28), and surgery (hazard ratio: 1.11, 95% CI: 1.02-1.21). Cigarette smoking and CD family history were also significantly associated with surgery. NOD2 carriers (all heterozygotes) were more common among CD cases than controls (8.2 vs. 2.1%; OR 4.17%, 95% CI: 1.18-14.69). The NOD2 mutation population attributable risk was 6.2%.\nCONCLUSIONS: In comparison with whites, ASCA in AAs has a similar sensitivity but a lower specificity for CD. ASCA is associated with ileal involvement, complicated behavior, and surgery in AAs with CD. NOD2 is a risk gene for AA CD, although mutation frequency and population attributable risk are much lower than in whites.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/ajg.2009.575", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2690022", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690020", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690023", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690017", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690019", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690021", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2423971", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690024", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1019809", 
            "issn": [
              "0002-9270", 
              "1572-0241"
            ], 
            "name": "The American Journal of Gastroenterology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "105"
          }
        ], 
        "name": "NOD2 Mutations and Anti-Saccharomyces cerevisiae Antibodies Are Risk Factors for Crohn's Disease in African Americans", 
        "pagination": "ajg2009575", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "255edb32aae3e607813a8cb763c40094f9c62c067be3d7133663342bd9c336ac"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "19826411"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0421030"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ajg.2009.575"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1007845176"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ajg.2009.575", 
          "https://app.dimensions.ai/details/publication/pub.1007845176"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T11:29", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000357_0000000357/records_99289_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/ajg2009575"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ajg.2009.575'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ajg.2009.575'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ajg.2009.575'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ajg.2009.575'


     

    This table displays all metadata directly associated to this object as RDF triples.

    423 TRIPLES      21 PREDICATES      95 URIs      36 LITERALS      24 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ajg.2009.575 schema:about N14508946e98049d7b30727bb7f83db61
    2 N1a18e579029b425ea6bacaf39c2c1c52
    3 N217c7cdc2a0d47b8bc9cdaebebcb51eb
    4 N24deed7599f744c9a41f2446a03190c5
    5 N290e751e4afd41cf8bb617af82098832
    6 N365e817329f4460383e95ae9951103f4
    7 N3d04870730a54570b8fe15a6e7704148
    8 N59bc77f8be984239baaaaa4ed06fd272
    9 N70adb11811f542c0a2d0cb0919b60dcb
    10 N7559bd7bae0e462387bf3ddc759da474
    11 N7c9625ca05774003bfd782bf973e2590
    12 N7da1f35f91e748dbab2daf1d7dd87cc4
    13 Na42ad5e00b7a41148e5455c6ec69e54e
    14 Naffe3a65f6614a6ba75777cbcfcb4477
    15 Nfd8537440fd14c958d8eb8262b90346b
    16 anzsrc-for:21
    17 anzsrc-for:2103
    18 schema:author Nf5b48a613f21435b98f6c7ceb3408879
    19 schema:citation sg:pub.10.1007/s00251-008-0274-6
    20 sg:pub.10.1007/s00384-003-0557-1
    21 sg:pub.10.1038/35079107
    22 sg:pub.10.1038/35079114
    23 sg:pub.10.1038/sj.ejhg.5200897
    24 sg:pub.10.1111/j.1572-0241.2001.03613.x
    25 sg:pub.10.1111/j.1572-0241.2004.40304.x
    26 sg:pub.10.1111/j.1572-0241.2004.40486.x
    27 sg:pub.10.1111/j.1572-0241.2005.00233.x
    28 sg:pub.10.1111/j.1572-0241.2005.40705.x
    29 sg:pub.10.1111/j.1572-0241.2006.00504.x
    30 sg:pub.10.1111/j.1572-0241.2006.00926.x
    31 sg:pub.10.1111/j.1572-0241.2007.01149.x
    32 https://app.dimensions.ai/details/publication/pub.1077040877
    33 https://doi.org/10.1002/ibd.20031
    34 https://doi.org/10.1002/ibd.20047
    35 https://doi.org/10.1002/ibd.20144
    36 https://doi.org/10.1002/ibd.20146
    37 https://doi.org/10.1002/ibd.3780060103
    38 https://doi.org/10.1016/0016-5085(92)90317-r
    39 https://doi.org/10.1016/j.mcp.2005.03.001
    40 https://doi.org/10.1016/s0022-3476(98)70187-8
    41 https://doi.org/10.1016/s0140-6736(02)08590-2
    42 https://doi.org/10.1016/s1590-8658(01)80692-7
    43 https://doi.org/10.1053/gast.1996.v111.pm8780559
    44 https://doi.org/10.1053/gast.1996.v111.pm8780560
    45 https://doi.org/10.1053/gast.2001.22546
    46 https://doi.org/10.1053/gast.2002.32413
    47 https://doi.org/10.1053/gast.2002.32415
    48 https://doi.org/10.1053/gast.2002.34020
    49 https://doi.org/10.1053/gast.2002.35393
    50 https://doi.org/10.1053/j.gastro.2003.11.015
    51 https://doi.org/10.1086/339432
    52 https://doi.org/10.1086/341124
    53 https://doi.org/10.1097/00054725-200002000-00002
    54 https://doi.org/10.1097/00054725-200102000-00002
    55 https://doi.org/10.1097/00054725-200309000-00001
    56 https://doi.org/10.1097/00054725-200409000-00005
    57 https://doi.org/10.1097/00054725-200812001-00026
    58 https://doi.org/10.1097/00054725-200812003-00026
    59 https://doi.org/10.1097/01.mib.0000171279.05471.21
    60 https://doi.org/10.1097/01.mib.0000217767.98389.20
    61 https://doi.org/10.1097/mpg.0b013e3180335bb3
    62 https://doi.org/10.1111/j.1365-2249.2003.02392.x
    63 https://doi.org/10.1136/gut.2003.030734
    64 https://doi.org/10.1136/gut.2005.082909
    65 https://doi.org/10.1136/gut.42.6.788
    66 https://doi.org/10.1136/gut.47.4.487
    67 https://doi.org/10.1136/gut.52.4.558
    68 https://doi.org/10.1155/2005/269076
    69 https://doi.org/10.1371/journal.pone.0002769
    70 schema:datePublished 2010-02
    71 schema:datePublishedReg 2010-02-01
    72 schema:description OBJECTIVES: NOD2 mutations and anti-Saccharomyces cerevisiae antibodies (ASCAs) are established risk factors of Crohn's disease (CD) in whites but have not been assessed in African-American (AA) adults with CD. METHODS: AAs with CD and controls were recruited by the Mid-Atlantic African-American IBD Study as part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium. Genotyping for the three common CD NOD2 mutations (Leu1007fsinsC, G908R/2722g>c, and R702W/2104c>t) and ASCA enzyme-linked immunosorbent assays were performed in 183 AA CD patients and in 143 controls. Logistic regression was used to calculate adjusted odds ratios (ORs) for the association between ASCA and disease phenotype. RESULTS: ASCA sensitivity and specificity values were 70.5 and 70.4%, respectively. On univariate analysis, ASCA was significantly associated with younger age at diagnosis, ileal involvement, and complicated (stricturing/penetrating) behavior. On multivariate analysis, ASCA titer (per 25 Units) was associated with ileal involvement (OR 1.18, 95% confidence interval (CI): 1.04-1.34), complicated behavior (OR 1.13, 95% CI: 1.01-1.28), and surgery (hazard ratio: 1.11, 95% CI: 1.02-1.21). Cigarette smoking and CD family history were also significantly associated with surgery. NOD2 carriers (all heterozygotes) were more common among CD cases than controls (8.2 vs. 2.1%; OR 4.17%, 95% CI: 1.18-14.69). The NOD2 mutation population attributable risk was 6.2%. CONCLUSIONS: In comparison with whites, ASCA in AAs has a similar sensitivity but a lower specificity for CD. ASCA is associated with ileal involvement, complicated behavior, and surgery in AAs with CD. NOD2 is a risk gene for AA CD, although mutation frequency and population attributable risk are much lower than in whites.
    73 schema:genre research_article
    74 schema:inLanguage en
    75 schema:isAccessibleForFree true
    76 schema:isPartOf N2045d509fdea4de78f85272bc7e27e58
    77 N8ddfa467b99a451fa7575139005c8b9d
    78 sg:journal.1019809
    79 schema:name NOD2 Mutations and Anti-Saccharomyces cerevisiae Antibodies Are Risk Factors for Crohn's Disease in African Americans
    80 schema:pagination ajg2009575
    81 schema:productId N4cf7f0a63c5a4649a7e9903972834343
    82 N673e1682a88d43e89051298b0a380bf2
    83 Na24d66cae2664f7dbaee0e0c4b84f350
    84 Nd2b28c1dc3a548a6acdffe50a6e1fe51
    85 Nd407092a4241401cb5a4102571af1c9f
    86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007845176
    87 https://doi.org/10.1038/ajg.2009.575
    88 schema:sdDatePublished 2019-04-11T11:29
    89 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    90 schema:sdPublisher N501999a311f541b4ab3832630c989995
    91 schema:url http://www.nature.com/articles/ajg2009575
    92 sgo:license sg:explorer/license/
    93 sgo:sdDataset articles
    94 rdf:type schema:ScholarlyArticle
    95 N14508946e98049d7b30727bb7f83db61 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    96 schema:name African Americans
    97 rdf:type schema:DefinedTerm
    98 N1a18e579029b425ea6bacaf39c2c1c52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Female
    100 rdf:type schema:DefinedTerm
    101 N2045d509fdea4de78f85272bc7e27e58 schema:issueNumber 2
    102 rdf:type schema:PublicationIssue
    103 N217c7cdc2a0d47b8bc9cdaebebcb51eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    104 schema:name Nod2 Signaling Adaptor Protein
    105 rdf:type schema:DefinedTerm
    106 N24deed7599f744c9a41f2446a03190c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Young Adult
    108 rdf:type schema:DefinedTerm
    109 N290e751e4afd41cf8bb617af82098832 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Male
    111 rdf:type schema:DefinedTerm
    112 N2c8834f5f6d94b1594dc23414a9e40fa rdf:first sg:person.01007154501.77
    113 rdf:rest Nd86356343080479591f1e7d7bde2cc5d
    114 N31fb40437bcc4777b73fba3a94602f86 rdf:first sg:person.01121465153.25
    115 rdf:rest N3aba0777559c46248a04060881d88152
    116 N33d43a54335b40e584a63499bc55c124 rdf:first sg:person.01234556550.07
    117 rdf:rest Nfd8e8cf64e06489f9217a1695dee0238
    118 N365e817329f4460383e95ae9951103f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    119 schema:name Adult
    120 rdf:type schema:DefinedTerm
    121 N3aba0777559c46248a04060881d88152 rdf:first sg:person.015262716107.02
    122 rdf:rest N4fc75b84f5134adbbabbf9ac1e2b935d
    123 N3d04870730a54570b8fe15a6e7704148 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name Antibodies, Fungal
    125 rdf:type schema:DefinedTerm
    126 N4cf7f0a63c5a4649a7e9903972834343 schema:name doi
    127 schema:value 10.1038/ajg.2009.575
    128 rdf:type schema:PropertyValue
    129 N4f9172f142c14101949be2638f00d67f rdf:first sg:person.01000502162.86
    130 rdf:rest N6e9b522a9d624458820cea7dcc46d200
    131 N4fc75b84f5134adbbabbf9ac1e2b935d rdf:first sg:person.0731375235.07
    132 rdf:rest N2c8834f5f6d94b1594dc23414a9e40fa
    133 N501999a311f541b4ab3832630c989995 schema:name Springer Nature - SN SciGraph project
    134 rdf:type schema:Organization
    135 N5520829a835b490bbf078449529d6e97 rdf:first sg:person.01120330150.11
    136 rdf:rest N9d7379aa39b144cfa1401b15c7c4dd66
    137 N59bc77f8be984239baaaaa4ed06fd272 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Adolescent
    139 rdf:type schema:DefinedTerm
    140 N673e1682a88d43e89051298b0a380bf2 schema:name dimensions_id
    141 schema:value pub.1007845176
    142 rdf:type schema:PropertyValue
    143 N6e9b522a9d624458820cea7dcc46d200 rdf:first sg:person.07606672634.28
    144 rdf:rest Nc14b4cb05961457a871065827f46890e
    145 N70adb11811f542c0a2d0cb0919b60dcb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    146 schema:name Saccharomyces cerevisiae
    147 rdf:type schema:DefinedTerm
    148 N7559bd7bae0e462387bf3ddc759da474 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Crohn Disease
    150 rdf:type schema:DefinedTerm
    151 N7c9625ca05774003bfd782bf973e2590 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Humans
    153 rdf:type schema:DefinedTerm
    154 N7da1f35f91e748dbab2daf1d7dd87cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    155 schema:name Risk Factors
    156 rdf:type schema:DefinedTerm
    157 N8ddfa467b99a451fa7575139005c8b9d schema:volumeNumber 105
    158 rdf:type schema:PublicationVolume
    159 N9d7379aa39b144cfa1401b15c7c4dd66 rdf:first sg:person.01356355561.51
    160 rdf:rest Nbd84f458e5764633b1960e335b12ac6f
    161 Na24d66cae2664f7dbaee0e0c4b84f350 schema:name nlm_unique_id
    162 schema:value 0421030
    163 rdf:type schema:PropertyValue
    164 Na42ad5e00b7a41148e5455c6ec69e54e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    165 schema:name Mutation
    166 rdf:type schema:DefinedTerm
    167 Naffe3a65f6614a6ba75777cbcfcb4477 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    168 schema:name Sensitivity and Specificity
    169 rdf:type schema:DefinedTerm
    170 Nbd84f458e5764633b1960e335b12ac6f rdf:first sg:person.0742437133.07
    171 rdf:rest N31fb40437bcc4777b73fba3a94602f86
    172 Nc14b4cb05961457a871065827f46890e rdf:first sg:person.016644232277.39
    173 rdf:rest rdf:nil
    174 Nd2b28c1dc3a548a6acdffe50a6e1fe51 schema:name readcube_id
    175 schema:value 255edb32aae3e607813a8cb763c40094f9c62c067be3d7133663342bd9c336ac
    176 rdf:type schema:PropertyValue
    177 Nd407092a4241401cb5a4102571af1c9f schema:name pubmed_id
    178 schema:value 19826411
    179 rdf:type schema:PropertyValue
    180 Nd86356343080479591f1e7d7bde2cc5d rdf:first sg:person.0771421401.25
    181 rdf:rest N33d43a54335b40e584a63499bc55c124
    182 Nf5b48a613f21435b98f6c7ceb3408879 rdf:first sg:person.016431435207.83
    183 rdf:rest N5520829a835b490bbf078449529d6e97
    184 Nfd8537440fd14c958d8eb8262b90346b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    185 schema:name Case-Control Studies
    186 rdf:type schema:DefinedTerm
    187 Nfd8e8cf64e06489f9217a1695dee0238 rdf:first sg:person.01267614456.23
    188 rdf:rest N4f9172f142c14101949be2638f00d67f
    189 anzsrc-for:21 schema:inDefinedTermSet anzsrc-for:
    190 schema:name History and Archaeology
    191 rdf:type schema:DefinedTerm
    192 anzsrc-for:2103 schema:inDefinedTermSet anzsrc-for:
    193 schema:name Historical Studies
    194 rdf:type schema:DefinedTerm
    195 sg:grant.2423971 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    196 rdf:type schema:MonetaryGrant
    197 sg:grant.2690017 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    198 rdf:type schema:MonetaryGrant
    199 sg:grant.2690019 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    200 rdf:type schema:MonetaryGrant
    201 sg:grant.2690020 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    202 rdf:type schema:MonetaryGrant
    203 sg:grant.2690021 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    204 rdf:type schema:MonetaryGrant
    205 sg:grant.2690022 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    206 rdf:type schema:MonetaryGrant
    207 sg:grant.2690023 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    208 rdf:type schema:MonetaryGrant
    209 sg:grant.2690024 http://pending.schema.org/fundedItem sg:pub.10.1038/ajg.2009.575
    210 rdf:type schema:MonetaryGrant
    211 sg:journal.1019809 schema:issn 0002-9270
    212 1572-0241
    213 schema:name The American Journal of Gastroenterology
    214 rdf:type schema:Periodical
    215 sg:person.01000502162.86 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    216 schema:familyName Bayless
    217 schema:givenName Theodore M
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000502162.86
    219 rdf:type schema:Person
    220 sg:person.01007154501.77 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
    221 schema:familyName Valentine
    222 schema:givenName John F
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007154501.77
    224 rdf:type schema:Person
    225 sg:person.01120330150.11 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
    226 schema:familyName Nguyen
    227 schema:givenName Geoffrey C
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120330150.11
    229 rdf:type schema:Person
    230 sg:person.01121465153.25 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
    231 schema:familyName Isaacs
    232 schema:givenName Kim L
    233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121465153.25
    234 rdf:type schema:Person
    235 sg:person.01234556550.07 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    236 schema:familyName Harris
    237 schema:givenName Mary L
    238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234556550.07
    239 rdf:type schema:Person
    240 sg:person.01267614456.23 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    241 schema:familyName Oliva-Hemker
    242 schema:givenName Maria
    243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267614456.23
    244 rdf:type schema:Person
    245 sg:person.01356355561.51 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    246 schema:familyName Talor
    247 schema:givenName Monica Vladut
    248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356355561.51
    249 rdf:type schema:Person
    250 sg:person.015262716107.02 schema:affiliation https://www.grid.ac/institutes/grid.25879.31
    251 schema:familyName Lewis
    252 schema:givenName James D
    253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015262716107.02
    254 rdf:type schema:Person
    255 sg:person.016431435207.83 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    256 schema:familyName Dassopoulos
    257 schema:givenName Themistocles
    258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016431435207.83
    259 rdf:type schema:Person
    260 sg:person.016644232277.39 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    261 schema:familyName Brant
    262 schema:givenName Steven R
    263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016644232277.39
    264 rdf:type schema:Person
    265 sg:person.0731375235.07 schema:affiliation https://www.grid.ac/institutes/grid.415235.4
    266 schema:familyName Gold
    267 schema:givenName Michael S
    268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731375235.07
    269 rdf:type schema:Person
    270 sg:person.0742437133.07 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    271 schema:familyName Datta
    272 schema:givenName Lisa Wu
    273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742437133.07
    274 rdf:type schema:Person
    275 sg:person.07606672634.28 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    276 schema:familyName Burek
    277 schema:givenName C Lynne
    278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07606672634.28
    279 rdf:type schema:Person
    280 sg:person.0771421401.25 schema:affiliation https://www.grid.ac/institutes/grid.257127.4
    281 schema:familyName Smoot
    282 schema:givenName Duane T
    283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771421401.25
    284 rdf:type schema:Person
    285 sg:pub.10.1007/s00251-008-0274-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030964719
    286 https://doi.org/10.1007/s00251-008-0274-6
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1007/s00384-003-0557-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021587892
    289 https://doi.org/10.1007/s00384-003-0557-1
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1038/35079107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031360950
    292 https://doi.org/10.1038/35079107
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1038/35079114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030806509
    295 https://doi.org/10.1038/35079114
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1038/sj.ejhg.5200897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011406469
    298 https://doi.org/10.1038/sj.ejhg.5200897
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1111/j.1572-0241.2001.03613.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025593726
    301 https://doi.org/10.1111/j.1572-0241.2001.03613.x
    302 rdf:type schema:CreativeWork
    303 sg:pub.10.1111/j.1572-0241.2004.40304.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028921167
    304 https://doi.org/10.1111/j.1572-0241.2004.40304.x
    305 rdf:type schema:CreativeWork
    306 sg:pub.10.1111/j.1572-0241.2004.40486.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018047226
    307 https://doi.org/10.1111/j.1572-0241.2004.40486.x
    308 rdf:type schema:CreativeWork
    309 sg:pub.10.1111/j.1572-0241.2005.00233.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040810353
    310 https://doi.org/10.1111/j.1572-0241.2005.00233.x
    311 rdf:type schema:CreativeWork
    312 sg:pub.10.1111/j.1572-0241.2005.40705.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014780630
    313 https://doi.org/10.1111/j.1572-0241.2005.40705.x
    314 rdf:type schema:CreativeWork
    315 sg:pub.10.1111/j.1572-0241.2006.00504.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043121940
    316 https://doi.org/10.1111/j.1572-0241.2006.00504.x
    317 rdf:type schema:CreativeWork
    318 sg:pub.10.1111/j.1572-0241.2006.00926.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006636141
    319 https://doi.org/10.1111/j.1572-0241.2006.00926.x
    320 rdf:type schema:CreativeWork
    321 sg:pub.10.1111/j.1572-0241.2007.01149.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001274568
    322 https://doi.org/10.1111/j.1572-0241.2007.01149.x
    323 rdf:type schema:CreativeWork
    324 https://app.dimensions.ai/details/publication/pub.1077040877 schema:CreativeWork
    325 https://doi.org/10.1002/ibd.20031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043702842
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1002/ibd.20047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045490322
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1002/ibd.20144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046883242
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1002/ibd.20146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034922102
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1002/ibd.3780060103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049055320
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1016/0016-5085(92)90317-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1045551170
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1016/j.mcp.2005.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033405794
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1016/s0022-3476(98)70187-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032936191
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1016/s0140-6736(02)08590-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010754431
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1016/s1590-8658(01)80692-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051845687
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1053/gast.1996.v111.pm8780559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006910829
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1053/gast.1996.v111.pm8780560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013203466
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1053/gast.2001.22546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025520718
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1053/gast.2002.32413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021871792
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1053/gast.2002.32415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029624284
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1053/gast.2002.34020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034708505
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1053/gast.2002.35393 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028345248
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1053/j.gastro.2003.11.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004273091
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1086/339432 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026249532
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1086/341124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032943926
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1097/00054725-200002000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021029359
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1097/00054725-200102000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036804048
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1097/00054725-200309000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023060757
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1097/00054725-200409000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018958470
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1097/00054725-200812001-00026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036740608
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1097/00054725-200812003-00026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006850847
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1097/01.mib.0000171279.05471.21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042523868
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1097/01.mib.0000217767.98389.20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029470448
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1097/mpg.0b013e3180335bb3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019360513
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1111/j.1365-2249.2003.02392.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037117711
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1136/gut.2003.030734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047153015
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1136/gut.2005.082909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018299078
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1136/gut.42.6.788 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041111311
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1136/gut.47.4.487 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004745588
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1136/gut.52.4.558 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051926100
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1155/2005/269076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028822302
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1371/journal.pone.0002769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033675407
    398 rdf:type schema:CreativeWork
    399 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
    400 schema:name Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    401 rdf:type schema:Organization
    402 https://www.grid.ac/institutes/grid.15276.37 schema:alternateName University of Florida
    403 schema:name Department of Medicine, University of Florida, Gainesville, Florida, USA
    404 rdf:type schema:Organization
    405 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
    406 schema:name Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    407 Mount Sinai Hospital IBD Centre, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    408 rdf:type schema:Organization
    409 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
    410 schema:name Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    411 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    412 Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    413 Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    414 rdf:type schema:Organization
    415 https://www.grid.ac/institutes/grid.257127.4 schema:alternateName Howard University
    416 schema:name Department of Medicine, Howard University, Washington, DC, USA
    417 rdf:type schema:Organization
    418 https://www.grid.ac/institutes/grid.25879.31 schema:alternateName University of Pennsylvania
    419 schema:name Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    420 rdf:type schema:Organization
    421 https://www.grid.ac/institutes/grid.415235.4 schema:alternateName MedStar Washington Hospital Center
    422 schema:name Department of Medicine, Washington Hospital Center, Washington, DC, USA
    423 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...