Mining the human genome using microarrays of open reading frames View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-11

AUTHORS

Sharron G. Penn, David R. Rank, David K. Hanzel, David L. Barker

ABSTRACT

To test the hypothesis that the human genome project will uncover many genes not previously discovered by sequencing of expressed sequence tags (ESTs), we designed and produced a set of microarrays using probes based on open reading frames (ORFs) in 350 Mb of finished and draft human sequence. Our approach aims to identify all genes directly from genomic sequence by querying gene expression. We analysed genomic sequence with a suite of ORF prediction programs, selected approximately one ORF per gene, amplified the ORFs from genomic DNA and arrayed the amplicons onto treated glass slides. Of the first 10,000 arrayed ORFs, 31% are completely novel and 29% are similar, but not identical, to sequences in public databases. Approximately one-half of these are expressed in the tissues we queried by microarray. Subsequent verification by other techniques confirmed expression of several of the novel genes. Expressed sequence tags (ESTs) have yielded vast amounts of data, but our results indicate that many genes in the human genome will only be found by genomic sequencing. More... »

PAGES

315

References to SciGraph publications

Journal

TITLE

Nature Genetics

ISSUE

3

VOLUME

26

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/81613

DOI

http://dx.doi.org/10.1038/81613

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043900588

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11062470


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Expressed Sequence Tags", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Profiling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Human Genome Project", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotide Array Sequence Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Open Reading Frames", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organ Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Homology, Nucleic Acid", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "GE Healthcare (United States)", 
          "id": "https://www.grid.ac/institutes/grid.474545.3", 
          "name": [
            "Advanced Research Team, Molecular Dynamics Inc., Sunnyvale, California, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Penn", 
        "givenName": "Sharron G.", 
        "id": "sg:person.01056332353.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056332353.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "GE Healthcare (United States)", 
          "id": "https://www.grid.ac/institutes/grid.474545.3", 
          "name": [
            "Advanced Research Team, Molecular Dynamics Inc., Sunnyvale, California, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rank", 
        "givenName": "David R.", 
        "id": "sg:person.01031427155.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031427155.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "GE Healthcare (United States)", 
          "id": "https://www.grid.ac/institutes/grid.474545.3", 
          "name": [
            "Advanced Research Team, Molecular Dynamics Inc., Sunnyvale, California, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanzel", 
        "givenName": "David K.", 
        "id": "sg:person.01311654475.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311654475.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Illumina (United States)", 
          "id": "https://www.grid.ac/institutes/grid.185669.5", 
          "name": [
            "Illumina, Inc., San Diego, California, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barker", 
        "givenName": "David L.", 
        "id": "sg:person.01005020520.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005020520.83"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ng0497supp-415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007964487", 
          "https://doi.org/10.1038/ng0497supp-415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0497supp-415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007964487", 
          "https://doi.org/10.1038/ng0497supp-415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.88.24.11261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013591162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(05)80360-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013618994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/22.24.5156", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021104151"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0968-0004(99)01375-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023773805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1996.0298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034621866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(94)90415-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042493955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1020700117665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046969501", 
          "https://doi.org/10.1023/a:1020700117665"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/990031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048671863", 
          "https://doi.org/10.1038/990031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/990031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048671863", 
          "https://doi.org/10.1038/990031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0166-2236(98)01264-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049340285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-510x(95)00208-j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052688042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082415674", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083203603", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2000-11", 
    "datePublishedReg": "2000-11-01", 
    "description": "To test the hypothesis that the human genome project will uncover many genes not previously discovered by sequencing of expressed sequence tags (ESTs), we designed and produced a set of microarrays using probes based on open reading frames (ORFs) in 350 Mb of finished and draft human sequence. Our approach aims to identify all genes directly from genomic sequence by querying gene expression. We analysed genomic sequence with a suite of ORF prediction programs, selected approximately one ORF per gene, amplified the ORFs from genomic DNA and arrayed the amplicons onto treated glass slides. Of the first 10,000 arrayed ORFs, 31% are completely novel and 29% are similar, but not identical, to sequences in public databases. Approximately one-half of these are expressed in the tissues we queried by microarray. Subsequent verification by other techniques confirmed expression of several of the novel genes. Expressed sequence tags (ESTs) have yielded vast amounts of data, but our results indicate that many genes in the human genome will only be found by genomic sequencing.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/81613", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1103138", 
        "issn": [
          "1061-4036", 
          "1546-1718"
        ], 
        "name": "Nature Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "name": "Mining the human genome using microarrays of open reading frames", 
    "pagination": "315", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d11d9945f8408a9d094a2b79f33f27b7ad4c892e047b0f37c2c80d6570cca636"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11062470"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9216904"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/81613"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1043900588"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/81613", 
      "https://app.dimensions.ai/details/publication/pub.1043900588"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87082_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/ng1100_315"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/81613'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/81613'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/81613'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/81613'


 

This table displays all metadata directly associated to this object as RDF triples.

189 TRIPLES      21 PREDICATES      56 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/81613 schema:about N04d9a46d63f84c4a959d868055c5d9e0
2 N48e07cc0223d4f1585769bf914fec085
3 N5f865b509ad74e6b941e3bd928050d18
4 N68f10b5592c34a39ac671a70693cc720
5 N749a3d3db29e47b69c6c0a356fc1ebc1
6 N774a2e0459404391a26d161281559df3
7 N7fbc7b8a23b94ca8a142555ba9f00036
8 N95688225d5554ff08ba157ee0c56db46
9 N9bac6a52e3fb498da248c12dd2a82d85
10 Na7d71ff2164c446c80f9206e83de701c
11 Nbc24d0636be0409a9a913d47f3a4fbeb
12 Nd17342adf92a4377b817bc9e262f0ec0
13 Nd359cebf53564c55a392f1a3fb2088bd
14 Ne599ed0f5ff94f40a7e3178e7c9faa52
15 anzsrc-for:06
16 anzsrc-for:0604
17 schema:author N4868460361f549739c1fffae7df3e662
18 schema:citation sg:pub.10.1023/a:1020700117665
19 sg:pub.10.1038/990031
20 sg:pub.10.1038/ng0497supp-415
21 https://app.dimensions.ai/details/publication/pub.1082415674
22 https://app.dimensions.ai/details/publication/pub.1083203603
23 https://doi.org/10.1006/geno.1996.0298
24 https://doi.org/10.1016/0022-510x(95)00208-j
25 https://doi.org/10.1016/0896-6273(94)90415-4
26 https://doi.org/10.1016/s0022-2836(05)80360-2
27 https://doi.org/10.1016/s0166-2236(98)01264-8
28 https://doi.org/10.1016/s0968-0004(99)01375-4
29 https://doi.org/10.1073/pnas.88.24.11261
30 https://doi.org/10.1093/nar/22.24.5156
31 schema:datePublished 2000-11
32 schema:datePublishedReg 2000-11-01
33 schema:description To test the hypothesis that the human genome project will uncover many genes not previously discovered by sequencing of expressed sequence tags (ESTs), we designed and produced a set of microarrays using probes based on open reading frames (ORFs) in 350 Mb of finished and draft human sequence. Our approach aims to identify all genes directly from genomic sequence by querying gene expression. We analysed genomic sequence with a suite of ORF prediction programs, selected approximately one ORF per gene, amplified the ORFs from genomic DNA and arrayed the amplicons onto treated glass slides. Of the first 10,000 arrayed ORFs, 31% are completely novel and 29% are similar, but not identical, to sequences in public databases. Approximately one-half of these are expressed in the tissues we queried by microarray. Subsequent verification by other techniques confirmed expression of several of the novel genes. Expressed sequence tags (ESTs) have yielded vast amounts of data, but our results indicate that many genes in the human genome will only be found by genomic sequencing.
34 schema:genre research_article
35 schema:inLanguage en
36 schema:isAccessibleForFree false
37 schema:isPartOf N0f4b496f65bb4be9980d64a3542559d8
38 Nbe014126746343019911bec7ed992251
39 sg:journal.1103138
40 schema:name Mining the human genome using microarrays of open reading frames
41 schema:pagination 315
42 schema:productId N03aa4269f4164e45bc0011b7169d63e5
43 N1b62b262ba96468682e24895b7e9b6c0
44 N388f5ad59d1a40aa9f067b90e2776066
45 N64731960318d4080907bedd2a79fde43
46 N892ff708c63a44629897b9ba76dc3a88
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043900588
48 https://doi.org/10.1038/81613
49 schema:sdDatePublished 2019-04-11T12:22
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher N947a2eba8fde4c4ea852f01259c5c1a9
52 schema:url https://www.nature.com/articles/ng1100_315
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N00dc825ebe3e4110976bead50cdd0f47 rdf:first sg:person.01005020520.83
57 rdf:rest rdf:nil
58 N03aa4269f4164e45bc0011b7169d63e5 schema:name nlm_unique_id
59 schema:value 9216904
60 rdf:type schema:PropertyValue
61 N04d9a46d63f84c4a959d868055c5d9e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Models, Genetic
63 rdf:type schema:DefinedTerm
64 N0f4b496f65bb4be9980d64a3542559d8 schema:issueNumber 3
65 rdf:type schema:PublicationIssue
66 N1b62b262ba96468682e24895b7e9b6c0 schema:name pubmed_id
67 schema:value 11062470
68 rdf:type schema:PropertyValue
69 N388f5ad59d1a40aa9f067b90e2776066 schema:name readcube_id
70 schema:value d11d9945f8408a9d094a2b79f33f27b7ad4c892e047b0f37c2c80d6570cca636
71 rdf:type schema:PropertyValue
72 N4868460361f549739c1fffae7df3e662 rdf:first sg:person.01056332353.82
73 rdf:rest N9855ebd44e8c42529704542afa9f80f0
74 N48e07cc0223d4f1585769bf914fec085 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Polymerase Chain Reaction
76 rdf:type schema:DefinedTerm
77 N5f865b509ad74e6b941e3bd928050d18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Gene Expression Profiling
79 rdf:type schema:DefinedTerm
80 N64731960318d4080907bedd2a79fde43 schema:name doi
81 schema:value 10.1038/81613
82 rdf:type schema:PropertyValue
83 N68f10b5592c34a39ac671a70693cc720 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Human Genome Project
85 rdf:type schema:DefinedTerm
86 N749a3d3db29e47b69c6c0a356fc1ebc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Genome, Human
88 rdf:type schema:DefinedTerm
89 N774a2e0459404391a26d161281559df3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Oligonucleotide Array Sequence Analysis
91 rdf:type schema:DefinedTerm
92 N7a5ee56c999e4ae1a51f6a758c818035 rdf:first sg:person.01311654475.38
93 rdf:rest N00dc825ebe3e4110976bead50cdd0f47
94 N7fbc7b8a23b94ca8a142555ba9f00036 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Sequence Analysis, DNA
96 rdf:type schema:DefinedTerm
97 N892ff708c63a44629897b9ba76dc3a88 schema:name dimensions_id
98 schema:value pub.1043900588
99 rdf:type schema:PropertyValue
100 N947a2eba8fde4c4ea852f01259c5c1a9 schema:name Springer Nature - SN SciGraph project
101 rdf:type schema:Organization
102 N95688225d5554ff08ba157ee0c56db46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Exons
104 rdf:type schema:DefinedTerm
105 N9855ebd44e8c42529704542afa9f80f0 rdf:first sg:person.01031427155.88
106 rdf:rest N7a5ee56c999e4ae1a51f6a758c818035
107 N9bac6a52e3fb498da248c12dd2a82d85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Expressed Sequence Tags
109 rdf:type schema:DefinedTerm
110 Na7d71ff2164c446c80f9206e83de701c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Organ Specificity
112 rdf:type schema:DefinedTerm
113 Nbc24d0636be0409a9a913d47f3a4fbeb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Open Reading Frames
115 rdf:type schema:DefinedTerm
116 Nbe014126746343019911bec7ed992251 schema:volumeNumber 26
117 rdf:type schema:PublicationVolume
118 Nd17342adf92a4377b817bc9e262f0ec0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Humans
120 rdf:type schema:DefinedTerm
121 Nd359cebf53564c55a392f1a3fb2088bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Sequence Homology, Nucleic Acid
123 rdf:type schema:DefinedTerm
124 Ne599ed0f5ff94f40a7e3178e7c9faa52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Cell Line
126 rdf:type schema:DefinedTerm
127 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
128 schema:name Biological Sciences
129 rdf:type schema:DefinedTerm
130 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
131 schema:name Genetics
132 rdf:type schema:DefinedTerm
133 sg:journal.1103138 schema:issn 1061-4036
134 1546-1718
135 schema:name Nature Genetics
136 rdf:type schema:Periodical
137 sg:person.01005020520.83 schema:affiliation https://www.grid.ac/institutes/grid.185669.5
138 schema:familyName Barker
139 schema:givenName David L.
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005020520.83
141 rdf:type schema:Person
142 sg:person.01031427155.88 schema:affiliation https://www.grid.ac/institutes/grid.474545.3
143 schema:familyName Rank
144 schema:givenName David R.
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031427155.88
146 rdf:type schema:Person
147 sg:person.01056332353.82 schema:affiliation https://www.grid.ac/institutes/grid.474545.3
148 schema:familyName Penn
149 schema:givenName Sharron G.
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056332353.82
151 rdf:type schema:Person
152 sg:person.01311654475.38 schema:affiliation https://www.grid.ac/institutes/grid.474545.3
153 schema:familyName Hanzel
154 schema:givenName David K.
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311654475.38
156 rdf:type schema:Person
157 sg:pub.10.1023/a:1020700117665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046969501
158 https://doi.org/10.1023/a:1020700117665
159 rdf:type schema:CreativeWork
160 sg:pub.10.1038/990031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048671863
161 https://doi.org/10.1038/990031
162 rdf:type schema:CreativeWork
163 sg:pub.10.1038/ng0497supp-415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007964487
164 https://doi.org/10.1038/ng0497supp-415
165 rdf:type schema:CreativeWork
166 https://app.dimensions.ai/details/publication/pub.1082415674 schema:CreativeWork
167 https://app.dimensions.ai/details/publication/pub.1083203603 schema:CreativeWork
168 https://doi.org/10.1006/geno.1996.0298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034621866
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/0022-510x(95)00208-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1052688042
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/0896-6273(94)90415-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042493955
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/s0022-2836(05)80360-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013618994
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/s0166-2236(98)01264-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049340285
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/s0968-0004(99)01375-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023773805
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1073/pnas.88.24.11261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013591162
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1093/nar/22.24.5156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021104151
183 rdf:type schema:CreativeWork
184 https://www.grid.ac/institutes/grid.185669.5 schema:alternateName Illumina (United States)
185 schema:name Illumina, Inc., San Diego, California, USA.
186 rdf:type schema:Organization
187 https://www.grid.ac/institutes/grid.474545.3 schema:alternateName GE Healthcare (United States)
188 schema:name Advanced Research Team, Molecular Dynamics Inc., Sunnyvale, California, USA.
189 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...