From structure to function: Approaches and limitations View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-11-01

AUTHORS

J M Thornton, A E Todd, D Milburn, N Borkakoti, C A Orengo

ABSTRACT

This review presents a summary of current approaches to extract functional information from structural data on proteins and their complexes. While structural homologs may reveal possible biochemical functions (which may be hidden at the sequence level), elucidating the exact biological role of a protein in vivo will only be possible by including other results, such as data on expression and localization. More... »

PAGES

991-994

References to SciGraph publications

  • 1994-12. Protein superfamilles and domain superfolds in NATURE
  • 1998-09. Crystal structure of Escherichia coli HdeA in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/80784

    DOI

    http://dx.doi.org/10.1038/80784

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1011891528

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11104008


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