DNA nanotechnology: Chemical copying of connectivity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-11

AUTHORS

Lars Henning Eckardt, Kai Naumann, Wolf Matthias Pankau, Michael Rein, Markus Schweitzer, Norbert Windhab, Günter von Kiedrowski

ABSTRACT

Three-dimensional DNA nanoscaffolds such as supramolecular tetrahedra can self-assemble from tris-oligonucleotidyls — synthetic three-armed building blocks in which three identical or non-identical short DNA sequences are connected by a tris-linking backbone1,2. Here we show that the connectivity information contained in these building blocks can be copied by using template-directed tris-linking. This finding is a crucial step towards the replication of nanoarchitectures that are based on tris-oligonucleotidyls and to the realization of artificially self-replicating systems on a nanometre scale. More... »

PAGES

286-286

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/420286a

DOI

http://dx.doi.org/10.1038/420286a

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021780357

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12447432


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