Crystal structure of the nucleosome core particle at 2.8 Å resolution View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-09

AUTHORS

Karolin Luger, Armin W. Mäder, Robin K. Richmond, David F. Sargent, Timothy J. Richmond

ABSTRACT

The X-ray crystal structure of the nucleosome core particle of chromatin shows in atomic detail how the histone protein octamer is assembled and how 146 base pairs of DNA are organized into a superhelix around it. Both histone/histone and histone/DNA interactions depend on the histone fold domains and additional, well ordered structure elements extending from this motif. Histone amino-terminal tails pass over and between the gyres of the DNA superhelix to contact neighbouring particles. The lack of uniformity between multiple histone/DNA-binding sites causes the DNA to deviate from ideal superhelix geometry. More... »

PAGES

251

Journal

TITLE

Nature

ISSUE

6648

VOLUME

389

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/38444

    DOI

    http://dx.doi.org/10.1038/38444

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010210236

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/9305837


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    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/38444'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/38444'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/38444'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/38444'


     

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