Uncoupling cadherin-based adhesion from wingless signalling in Drosophila View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-10

AUTHORS

B Sanson, P White, J P Vincent

ABSTRACT

The Wnt genes encode secreted glycoproteins used in intercellular communication at multiple steps during development. Signalling by Wingless, the Drosophila Wnt-1 homologue, requires the activity of Armadillo, the homologue of vertebrate beta-catenin, which is a component of the cadherin/catenin complex at adherens junctions. The genetic link between wingless and armadillo suggests that cell fate specification and cell-cell adhesion might be controlled concurrently. For instance, in one extreme view, Wingless could specify cell fate entirely by modulating cell adhesion. Alternatively, it might signal independently of adherens junctions. To distinguish between these alternatives, we have expressed two polypeptides that have opposite effects on cadherin-dependent adhesion: full-length Drosophila E-cadherin and a dominant-negative truncated form. We found that overexpression of either construct mimics wingless phenotypes, thereby uncoupling changes in adhesion from signalling effects. We demonstrate that both constructs titrate Armadillo from a 'signalling' pool which is functionally distinct from the junctional pool. More... »

PAGES

627-630

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/383627a0

DOI

http://dx.doi.org/10.1038/383627a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033143139

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8857539


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Armadillo Domain Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cadherins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Adhesion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drosophila", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drosophila Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peptide Fragments", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Fusion Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Trans-Activators", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wings, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wnt1 Protein", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "MRC Laboratory of Molecular Biology", 
          "id": "https://www.grid.ac/institutes/grid.42475.30", 
          "name": [
            "Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sanson", 
        "givenName": "B", 
        "id": "sg:person.01152606450.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152606450.97"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "White", 
        "givenName": "P", 
        "type": "Person"
      }, 
      {
        "familyName": "Vincent", 
        "givenName": "J P", 
        "id": "sg:person.01324757126.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324757126.36"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1083/jcb.121.5.1133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000917974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.128.5.959", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002244006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.10.6.672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003375997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/332604a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004194453", 
          "https://doi.org/10.1038/332604a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/dbio.1994.1287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004897200"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(94)90069-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008294063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.3.1520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015390779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0959-4388(93)90036-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024345033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0959-4388(93)90036-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024345033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(92)90404-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027699856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0012-1606(76)90108-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028090744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.11.4246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030442469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.59.070190.001321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035150559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.1.1.37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035392157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.132.6.1105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035453621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(94)90057-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038298797"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0955-0674(92)90108-o", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039201826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.134.5.1283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042782159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367080a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046890704", 
          "https://doi.org/10.1038/367080a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.19.8813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048717583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.10.6.659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050929079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1989.tb03563.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079359564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079607522", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082674430", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082680619", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082709342", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082711227", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082731176", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082865624", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082886306", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1996-10", 
    "datePublishedReg": "1996-10-01", 
    "description": "The Wnt genes encode secreted glycoproteins used in intercellular communication at multiple steps during development. Signalling by Wingless, the Drosophila Wnt-1 homologue, requires the activity of Armadillo, the homologue of vertebrate beta-catenin, which is a component of the cadherin/catenin complex at adherens junctions. The genetic link between wingless and armadillo suggests that cell fate specification and cell-cell adhesion might be controlled concurrently. For instance, in one extreme view, Wingless could specify cell fate entirely by modulating cell adhesion. Alternatively, it might signal independently of adherens junctions. To distinguish between these alternatives, we have expressed two polypeptides that have opposite effects on cadherin-dependent adhesion: full-length Drosophila E-cadherin and a dominant-negative truncated form. We found that overexpression of either construct mimics wingless phenotypes, thereby uncoupling changes in adhesion from signalling effects. We demonstrate that both constructs titrate Armadillo from a 'signalling' pool which is functionally distinct from the junctional pool.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/383627a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6601", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "383"
      }
    ], 
    "name": "Uncoupling cadherin-based adhesion from wingless signalling in Drosophila", 
    "pagination": "627-630", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9de3a6c231d305e3ff0b55fc9a24b764881d94c7f4fd07f4583a4c8fabbacc52"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8857539"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/383627a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033143139"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/383627a0", 
      "https://app.dimensions.ai/details/publication/pub.1033143139"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:55", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/383627a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/383627a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/383627a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/383627a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/383627a0'


 

This table displays all metadata directly associated to this object as RDF triples.

233 TRIPLES      21 PREDICATES      76 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/383627a0 schema:about N059c3eba0b0349cc98fbb4e278946272
2 N07e7083278dd4ccfa5d9953fce0b9233
3 N1d3416403dea45498a4bc2633c55c696
4 N2ba3784ac2424c4082535b07167037b3
5 N47c1241b081e4f0494f6fbc2fa345044
6 N6955ad014f4b4429921b91432e86c9df
7 N6f5a2daeb8ac4d10bb5185c52c5642bb
8 N79e3e03cd96347319fbcd577c41f127e
9 N8572493034b444b9a7d43ec9461269a7
10 N8cd3ccf60a284d6fb29eca13758c8bbf
11 N9475698f2459459b95a7bbeec1512b8b
12 Na0dfdedad2314373a622bc6ba95b3e81
13 Naa7375bb180944459b3d3c2b83101e0b
14 Nad10a308b24b4429a32ce8b478af7932
15 Nd86d86c287f34d6aabe3c2a3973c60d2
16 Ndfa6ca97988f437d8714a7bc7139c1af
17 Nfe0a990d444f442c913db6fbf5b8c83f
18 Nfe9801a1840847a6a854dbd5b355420c
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author N86a6e8d2a24744ec8153fa306770160f
22 schema:citation sg:pub.10.1038/332604a0
23 sg:pub.10.1038/367080a0
24 https://app.dimensions.ai/details/publication/pub.1079607522
25 https://app.dimensions.ai/details/publication/pub.1082674430
26 https://app.dimensions.ai/details/publication/pub.1082680619
27 https://app.dimensions.ai/details/publication/pub.1082709342
28 https://app.dimensions.ai/details/publication/pub.1082711227
29 https://app.dimensions.ai/details/publication/pub.1082731176
30 https://app.dimensions.ai/details/publication/pub.1082865624
31 https://app.dimensions.ai/details/publication/pub.1082886306
32 https://doi.org/10.1002/j.1460-2075.1989.tb03563.x
33 https://doi.org/10.1006/dbio.1994.1287
34 https://doi.org/10.1016/0012-1606(76)90108-1
35 https://doi.org/10.1016/0092-8674(92)90404-z
36 https://doi.org/10.1016/0092-8674(94)90069-8
37 https://doi.org/10.1016/0955-0674(92)90108-o
38 https://doi.org/10.1016/0959-4388(93)90036-x
39 https://doi.org/10.1016/0968-0004(94)90057-4
40 https://doi.org/10.1073/pnas.87.11.4246
41 https://doi.org/10.1073/pnas.92.19.8813
42 https://doi.org/10.1074/jbc.271.3.1520
43 https://doi.org/10.1083/jcb.121.5.1133
44 https://doi.org/10.1083/jcb.128.5.959
45 https://doi.org/10.1083/jcb.132.6.1105
46 https://doi.org/10.1083/jcb.134.5.1283
47 https://doi.org/10.1091/mbc.1.1.37
48 https://doi.org/10.1101/gad.10.6.659
49 https://doi.org/10.1101/gad.10.6.672
50 https://doi.org/10.1146/annurev.bi.59.070190.001321
51 schema:datePublished 1996-10
52 schema:datePublishedReg 1996-10-01
53 schema:description The Wnt genes encode secreted glycoproteins used in intercellular communication at multiple steps during development. Signalling by Wingless, the Drosophila Wnt-1 homologue, requires the activity of Armadillo, the homologue of vertebrate beta-catenin, which is a component of the cadherin/catenin complex at adherens junctions. The genetic link between wingless and armadillo suggests that cell fate specification and cell-cell adhesion might be controlled concurrently. For instance, in one extreme view, Wingless could specify cell fate entirely by modulating cell adhesion. Alternatively, it might signal independently of adherens junctions. To distinguish between these alternatives, we have expressed two polypeptides that have opposite effects on cadherin-dependent adhesion: full-length Drosophila E-cadherin and a dominant-negative truncated form. We found that overexpression of either construct mimics wingless phenotypes, thereby uncoupling changes in adhesion from signalling effects. We demonstrate that both constructs titrate Armadillo from a 'signalling' pool which is functionally distinct from the junctional pool.
54 schema:genre research_article
55 schema:inLanguage en
56 schema:isAccessibleForFree false
57 schema:isPartOf N42446e64dc1c4476b26e50aa679ba689
58 Nd1ce20be7a994bc99c7c2770c7af1621
59 sg:journal.1018957
60 schema:name Uncoupling cadherin-based adhesion from wingless signalling in Drosophila
61 schema:pagination 627-630
62 schema:productId N032898bae3eb46ada8d6a52afd25b5b4
63 N4cebd36202b24ed9b4eda808c5a77914
64 N6c173d70e3544c7ca86bc6b77dad7f4e
65 N7e67c0ac4fd94d3b8fa6597127b0174b
66 N7f2ddd4cef0142bdb1347d1d09a71e5e
67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033143139
68 https://doi.org/10.1038/383627a0
69 schema:sdDatePublished 2019-04-11T00:55
70 schema:sdLicense https://scigraph.springernature.com/explorer/license/
71 schema:sdPublisher N064bb1086e584e7bbd2cadd76f3fff71
72 schema:url http://www.nature.com/articles/383627a0
73 sgo:license sg:explorer/license/
74 sgo:sdDataset articles
75 rdf:type schema:ScholarlyArticle
76 N032898bae3eb46ada8d6a52afd25b5b4 schema:name doi
77 schema:value 10.1038/383627a0
78 rdf:type schema:PropertyValue
79 N059c3eba0b0349cc98fbb4e278946272 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Embryonic Induction
81 rdf:type schema:DefinedTerm
82 N064bb1086e584e7bbd2cadd76f3fff71 schema:name Springer Nature - SN SciGraph project
83 rdf:type schema:Organization
84 N07e7083278dd4ccfa5d9953fce0b9233 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Signal Transduction
86 rdf:type schema:DefinedTerm
87 N1d3416403dea45498a4bc2633c55c696 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Wnt1 Protein
89 rdf:type schema:DefinedTerm
90 N2ad8b746b84c4a78807ec9904bd913a9 rdf:first sg:person.01324757126.36
91 rdf:rest rdf:nil
92 N2ba3784ac2424c4082535b07167037b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Peptide Fragments
94 rdf:type schema:DefinedTerm
95 N42446e64dc1c4476b26e50aa679ba689 schema:volumeNumber 383
96 rdf:type schema:PublicationVolume
97 N47c1241b081e4f0494f6fbc2fa345044 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Cadherins
99 rdf:type schema:DefinedTerm
100 N4cebd36202b24ed9b4eda808c5a77914 schema:name pubmed_id
101 schema:value 8857539
102 rdf:type schema:PropertyValue
103 N521bf5430f644bdda4029c776823a180 schema:familyName White
104 schema:givenName P
105 rdf:type schema:Person
106 N6955ad014f4b4429921b91432e86c9df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Drosophila Proteins
108 rdf:type schema:DefinedTerm
109 N6c173d70e3544c7ca86bc6b77dad7f4e schema:name dimensions_id
110 schema:value pub.1033143139
111 rdf:type schema:PropertyValue
112 N6f5a2daeb8ac4d10bb5185c52c5642bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Female
114 rdf:type schema:DefinedTerm
115 N79e3e03cd96347319fbcd577c41f127e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Cell Adhesion
117 rdf:type schema:DefinedTerm
118 N7e67c0ac4fd94d3b8fa6597127b0174b schema:name readcube_id
119 schema:value 9de3a6c231d305e3ff0b55fc9a24b764881d94c7f4fd07f4583a4c8fabbacc52
120 rdf:type schema:PropertyValue
121 N7f2ddd4cef0142bdb1347d1d09a71e5e schema:name nlm_unique_id
122 schema:value 0410462
123 rdf:type schema:PropertyValue
124 N8572493034b444b9a7d43ec9461269a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Wings, Animal
126 rdf:type schema:DefinedTerm
127 N86485e51180046888c4b2d547b2fb50c rdf:first N521bf5430f644bdda4029c776823a180
128 rdf:rest N2ad8b746b84c4a78807ec9904bd913a9
129 N86a6e8d2a24744ec8153fa306770160f rdf:first sg:person.01152606450.97
130 rdf:rest N86485e51180046888c4b2d547b2fb50c
131 N8cd3ccf60a284d6fb29eca13758c8bbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Transcription Factors
133 rdf:type schema:DefinedTerm
134 N9475698f2459459b95a7bbeec1512b8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Animals
136 rdf:type schema:DefinedTerm
137 Na0dfdedad2314373a622bc6ba95b3e81 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Armadillo Domain Proteins
139 rdf:type schema:DefinedTerm
140 Naa7375bb180944459b3d3c2b83101e0b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Proto-Oncogene Proteins
142 rdf:type schema:DefinedTerm
143 Nad10a308b24b4429a32ce8b478af7932 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Drosophila
145 rdf:type schema:DefinedTerm
146 Nd1ce20be7a994bc99c7c2770c7af1621 schema:issueNumber 6601
147 rdf:type schema:PublicationIssue
148 Nd86d86c287f34d6aabe3c2a3973c60d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Recombinant Fusion Proteins
150 rdf:type schema:DefinedTerm
151 Ndfa6ca97988f437d8714a7bc7139c1af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Male
153 rdf:type schema:DefinedTerm
154 Nfe0a990d444f442c913db6fbf5b8c83f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Proteins
156 rdf:type schema:DefinedTerm
157 Nfe9801a1840847a6a854dbd5b355420c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Trans-Activators
159 rdf:type schema:DefinedTerm
160 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
161 schema:name Biological Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
164 schema:name Genetics
165 rdf:type schema:DefinedTerm
166 sg:journal.1018957 schema:issn 0090-0028
167 1476-4687
168 schema:name Nature
169 rdf:type schema:Periodical
170 sg:person.01152606450.97 schema:affiliation https://www.grid.ac/institutes/grid.42475.30
171 schema:familyName Sanson
172 schema:givenName B
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152606450.97
174 rdf:type schema:Person
175 sg:person.01324757126.36 schema:familyName Vincent
176 schema:givenName J P
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324757126.36
178 rdf:type schema:Person
179 sg:pub.10.1038/332604a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004194453
180 https://doi.org/10.1038/332604a0
181 rdf:type schema:CreativeWork
182 sg:pub.10.1038/367080a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046890704
183 https://doi.org/10.1038/367080a0
184 rdf:type schema:CreativeWork
185 https://app.dimensions.ai/details/publication/pub.1079607522 schema:CreativeWork
186 https://app.dimensions.ai/details/publication/pub.1082674430 schema:CreativeWork
187 https://app.dimensions.ai/details/publication/pub.1082680619 schema:CreativeWork
188 https://app.dimensions.ai/details/publication/pub.1082709342 schema:CreativeWork
189 https://app.dimensions.ai/details/publication/pub.1082711227 schema:CreativeWork
190 https://app.dimensions.ai/details/publication/pub.1082731176 schema:CreativeWork
191 https://app.dimensions.ai/details/publication/pub.1082865624 schema:CreativeWork
192 https://app.dimensions.ai/details/publication/pub.1082886306 schema:CreativeWork
193 https://doi.org/10.1002/j.1460-2075.1989.tb03563.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1079359564
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1006/dbio.1994.1287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004897200
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/0012-1606(76)90108-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028090744
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/0092-8674(92)90404-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1027699856
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/0092-8674(94)90069-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008294063
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/0955-0674(92)90108-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1039201826
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/0959-4388(93)90036-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024345033
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/0968-0004(94)90057-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038298797
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1073/pnas.87.11.4246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030442469
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1073/pnas.92.19.8813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048717583
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1074/jbc.271.3.1520 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015390779
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1083/jcb.121.5.1133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000917974
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1083/jcb.128.5.959 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002244006
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1083/jcb.132.6.1105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035453621
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1083/jcb.134.5.1283 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042782159
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1091/mbc.1.1.37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035392157
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1101/gad.10.6.659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050929079
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1101/gad.10.6.672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003375997
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1146/annurev.bi.59.070190.001321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035150559
230 rdf:type schema:CreativeWork
231 https://www.grid.ac/institutes/grid.42475.30 schema:alternateName MRC Laboratory of Molecular Biology
232 schema:name Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK.
233 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...