Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-09

AUTHORS

Min-Hao Kuo, James E. Brownell, Richard E. Sobel, Tamara A. Ranalli, Richard G. Cook, Diane G. Edmondson, Sharon Y. Roth, C. David Allis

ABSTRACT

THE yeast transcriptional adaptor1–3, Gcn5p, is a catalytic subunit of a nuclear (type A) histone acetyltransferase linking histone acetylation to gene activation4–6. Here we report that Gcn5p acetylates histones H3 and H4 non-randomly at specific lysines in the amino-terminal domains. Lysine 14 of H3 and lysines 8 and 16 of H4 are highly preferred acetylation sites for Gcn5p. We also demonstrate that lysine 9 is the preferred position of acetylation in newly synthesized yeast H3 in vivo. This finding, along with the fact that lysines 5 and 12 in H4 are predominant acetylation sites during chromatin assembly of many organisms7–11, indicates that Gcn5p acetylates a distinct set of lysines that do not overlap with those sites characteristically used by type B histone acetyltransferase s for histone deposition and chromatin assembly. More... »

PAGES

269-272

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/383269a0

DOI

http://dx.doi.org/10.1038/383269a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024313273

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8805705


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acetylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acetyltransferases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cattle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chickens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Binding Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fungal Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histone Acetyltransferases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lysine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Substrate Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tetrahymena thermophila", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription, Genetic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Biology, University of Rochester, 14627, Rochester, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.16416.34", 
          "name": [
            "Department of Biology, University of Rochester, 14627, Rochester, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kuo", 
        "givenName": "Min-Hao", 
        "id": "sg:person.0640474631.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640474631.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biology, University of Rochester, 14627, Rochester, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.16416.34", 
          "name": [
            "Department of Biology, University of Rochester, 14627, Rochester, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brownell", 
        "givenName": "James E.", 
        "id": "sg:person.01302364347.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302364347.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Microbiology and Immunology, Baylor College of Medicine, 77030, Houston, Texas, USA", 
          "id": "http://www.grid.ac/institutes/grid.39382.33", 
          "name": [
            "Department of Biology, University of Rochester, 14627, Rochester, New York, USA", 
            "Department of Microbiology and Immunology, Baylor College of Medicine, 77030, Houston, Texas, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sobel", 
        "givenName": "Richard E.", 
        "id": "sg:person.01160325607.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160325607.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biology, University of Rochester, 14627, Rochester, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.16416.34", 
          "name": [
            "Department of Biology, University of Rochester, 14627, Rochester, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ranalli", 
        "givenName": "Tamara A.", 
        "id": "sg:person.01165556153.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165556153.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry and Molecular Biology, M. D. Anderson Cancer Center, 77030, Houston, Texas, USA", 
          "id": "http://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Biochemistry and Molecular Biology, M. D. Anderson Cancer Center, 77030, Houston, Texas, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cook", 
        "givenName": "Richard G.", 
        "id": "sg:person.010356234162.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010356234162.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada", 
          "id": "http://www.grid.ac/institutes/grid.17091.3e", 
          "name": [
            "Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Edmondson", 
        "givenName": "Diane G.", 
        "id": "sg:person.01217521510.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217521510.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada", 
          "id": "http://www.grid.ac/institutes/grid.17091.3e", 
          "name": [
            "Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roth", 
        "givenName": "Sharon Y.", 
        "id": "sg:person.01265634710.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265634710.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biology, University of Rochester, 14627, Rochester, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.16416.34", 
          "name": [
            "Department of Biology, University of Rochester, 14627, Rochester, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Allis", 
        "givenName": "C. David", 
        "id": "sg:person.01044565073.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044565073.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00290718", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049797265", 
          "https://doi.org/10.1007/bf00290718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/382319a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052095488", 
          "https://doi.org/10.1038/382319a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1996-09", 
    "datePublishedReg": "1996-09-01", 
    "description": "THE yeast transcriptional adaptor1\u20133, Gcn5p, is a catalytic subunit of a nuclear (type A) histone acetyltransferase linking histone acetylation to gene activation4\u20136. Here we report that Gcn5p acetylates histones H3 and H4 non-randomly at specific lysines in the amino-terminal domains. Lysine 14 of H3 and lysines 8 and 16 of H4 are highly preferred acetylation sites for Gcn5p. We also demonstrate that lysine 9 is the preferred position of acetylation in newly synthesized yeast H3 in vivo. This finding, along with the fact that lysines 5 and 12 in H4 are predominant acetylation sites during chromatin assembly of many organisms7\u201311, indicates that Gcn5p acetylates a distinct set of lysines that do not overlap with those sites characteristically used by type B histone acetyltransferase s for histone deposition and chromatin assembly.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/383269a0", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6597", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "383"
      }
    ], 
    "keywords": [
      "chromatin assembly", 
      "histone H3", 
      "acetylation sites", 
      "specific lysines", 
      "amino-terminal domain", 
      "histone deposition", 
      "lysine 14", 
      "lysine 9", 
      "yeast H3", 
      "Gcn5p", 
      "catalytic subunit", 
      "histone acetylation", 
      "nuclear histones", 
      "H4", 
      "H3", 
      "distinct sets", 
      "acetylation", 
      "lysine", 
      "assembly", 
      "histones", 
      "sites", 
      "subunits", 
      "vivo", 
      "domain", 
      "preferred position", 
      "findings", 
      "position", 
      "set", 
      "fact", 
      "deposition", 
      "yeast transcriptional adaptor1", 
      "transcriptional adaptor1", 
      "adaptor1", 
      "activation4", 
      "predominant acetylation sites", 
      "organisms7", 
      "type B histone acetyltransferase s", 
      "B histone acetyltransferase s", 
      "histone acetyltransferase s", 
      "acetyltransferase s", 
      "Transcription-linked acetylation"
    ], 
    "name": "Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines", 
    "pagination": "269-272", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1024313273"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/383269a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8805705"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/383269a0", 
      "https://app.dimensions.ai/details/publication/pub.1024313273"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_292.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/383269a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/383269a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/383269a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/383269a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/383269a0'


 

This table displays all metadata directly associated to this object as RDF triples.

246 TRIPLES      22 PREDICATES      89 URIs      79 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/383269a0 schema:about N20c143afb61c424e9390c0a6a1d29fa6
2 N2766a7c695be485882205c270d6da074
3 N2d9cd02c44b6483f8f1c632d3dbce23b
4 N30f319b0e83745ed8cdbeb29a2f57d41
5 N3afb9b6af9254d09a6ce603cf807cafa
6 N4b4bf919633342ea9b2866c8e37c7661
7 N5d79aaabe2b84d7b87c6b70b2adecd8c
8 N73b13cfa466c42419313afb511a89145
9 N9914b93dc5b84c92b55b798432f67633
10 Na7e0044571204c748e3fbb99829870d0
11 Nac328d4bb03d4c09b9b1a967bfcb37ee
12 Nae374d73678f4e28a1cf00e7ef140874
13 Nb0889e57702d43b8bc55a5575921f93a
14 Nb9d9e0d76f2149adb0e07385df4d71d1
15 Nbb9f30d566d04fdd8819ec1440cc9351
16 Nbff19ea1eb084ed6953bbca9a59f9511
17 Ncfbff8962b844ee189cbaeb24e8c8ac7
18 Nf2176ab2d4d540b684f38dd413ae14d7
19 Nf3f6d96e186a48deb5d86356ceceb5c4
20 anzsrc-for:06
21 anzsrc-for:0604
22 schema:author N1d729acbc9b7445f99561b3844a2842d
23 schema:citation sg:pub.10.1007/bf00290718
24 sg:pub.10.1038/382319a0
25 schema:datePublished 1996-09
26 schema:datePublishedReg 1996-09-01
27 schema:description THE yeast transcriptional adaptor1–3, Gcn5p, is a catalytic subunit of a nuclear (type A) histone acetyltransferase linking histone acetylation to gene activation4–6. Here we report that Gcn5p acetylates histones H3 and H4 non-randomly at specific lysines in the amino-terminal domains. Lysine 14 of H3 and lysines 8 and 16 of H4 are highly preferred acetylation sites for Gcn5p. We also demonstrate that lysine 9 is the preferred position of acetylation in newly synthesized yeast H3 in vivo. This finding, along with the fact that lysines 5 and 12 in H4 are predominant acetylation sites during chromatin assembly of many organisms7–11, indicates that Gcn5p acetylates a distinct set of lysines that do not overlap with those sites characteristically used by type B histone acetyltransferase s for histone deposition and chromatin assembly.
28 schema:genre article
29 schema:inLanguage en
30 schema:isAccessibleForFree false
31 schema:isPartOf N1a4b9d81e37a45b49dadb34486aee241
32 Nfa0077d425b64389b983b0731fd1f012
33 sg:journal.1018957
34 schema:keywords B histone acetyltransferase s
35 Gcn5p
36 H3
37 H4
38 Transcription-linked acetylation
39 acetylation
40 acetylation sites
41 acetyltransferase s
42 activation4
43 adaptor1
44 amino-terminal domain
45 assembly
46 catalytic subunit
47 chromatin assembly
48 deposition
49 distinct sets
50 domain
51 fact
52 findings
53 histone H3
54 histone acetylation
55 histone acetyltransferase s
56 histone deposition
57 histones
58 lysine
59 lysine 14
60 lysine 9
61 nuclear histones
62 organisms7
63 position
64 predominant acetylation sites
65 preferred position
66 set
67 sites
68 specific lysines
69 subunits
70 transcriptional adaptor1
71 type B histone acetyltransferase s
72 vivo
73 yeast H3
74 yeast transcriptional adaptor1
75 schema:name Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines
76 schema:pagination 269-272
77 schema:productId N4aeccb38fce1459ca572f71432e368cb
78 Nf9a1cc066a884f6ba12b8c207d281966
79 Nfcccd5672031455dace9f40dad950958
80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024313273
81 https://doi.org/10.1038/383269a0
82 schema:sdDatePublished 2021-12-01T19:10
83 schema:sdLicense https://scigraph.springernature.com/explorer/license/
84 schema:sdPublisher Ne3ec6a4eaf044551812213f822a92856
85 schema:url https://doi.org/10.1038/383269a0
86 sgo:license sg:explorer/license/
87 sgo:sdDataset articles
88 rdf:type schema:ScholarlyArticle
89 N0d94ca8faa1241868ba7d3319e095e86 rdf:first sg:person.010356234162.72
90 rdf:rest Nf3ab59ae810d49f3a51f3ff4b7dcf057
91 N1a4b9d81e37a45b49dadb34486aee241 schema:issueNumber 6597
92 rdf:type schema:PublicationIssue
93 N1d729acbc9b7445f99561b3844a2842d rdf:first sg:person.0640474631.79
94 rdf:rest Ne24e841481644dd59cc2c47ad0fa0f6a
95 N20c143afb61c424e9390c0a6a1d29fa6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Animals
97 rdf:type schema:DefinedTerm
98 N2766a7c695be485882205c270d6da074 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name DNA-Binding Proteins
100 rdf:type schema:DefinedTerm
101 N2a46e55d183847c2a815d4e3f076135a rdf:first sg:person.01265634710.97
102 rdf:rest Nd91d6557dd7d4c1cbf0a3254dc7c39f5
103 N2d9cd02c44b6483f8f1c632d3dbce23b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Molecular Sequence Data
105 rdf:type schema:DefinedTerm
106 N30f319b0e83745ed8cdbeb29a2f57d41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Recombinant Proteins
108 rdf:type schema:DefinedTerm
109 N3afb9b6af9254d09a6ce603cf807cafa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Amino Acid Sequence
111 rdf:type schema:DefinedTerm
112 N4406626bd9d145c586cc18eea1e8d8eb rdf:first sg:person.01165556153.25
113 rdf:rest N0d94ca8faa1241868ba7d3319e095e86
114 N4aeccb38fce1459ca572f71432e368cb schema:name pubmed_id
115 schema:value 8805705
116 rdf:type schema:PropertyValue
117 N4b4bf919633342ea9b2866c8e37c7661 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Chickens
119 rdf:type schema:DefinedTerm
120 N5d79aaabe2b84d7b87c6b70b2adecd8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Transcription, Genetic
122 rdf:type schema:DefinedTerm
123 N73b13cfa466c42419313afb511a89145 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Tetrahymena thermophila
125 rdf:type schema:DefinedTerm
126 N9914b93dc5b84c92b55b798432f67633 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Lysine
128 rdf:type schema:DefinedTerm
129 N994b6f09fcb847d4af865d3ef0300721 rdf:first sg:person.01160325607.88
130 rdf:rest N4406626bd9d145c586cc18eea1e8d8eb
131 Na7e0044571204c748e3fbb99829870d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Cattle
133 rdf:type schema:DefinedTerm
134 Nac328d4bb03d4c09b9b1a967bfcb37ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Fungal Proteins
136 rdf:type schema:DefinedTerm
137 Nae374d73678f4e28a1cf00e7ef140874 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Histone Acetyltransferases
139 rdf:type schema:DefinedTerm
140 Nb0889e57702d43b8bc55a5575921f93a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Protein Kinases
142 rdf:type schema:DefinedTerm
143 Nb9d9e0d76f2149adb0e07385df4d71d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Acetyltransferases
145 rdf:type schema:DefinedTerm
146 Nbb9f30d566d04fdd8819ec1440cc9351 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Saccharomyces cerevisiae
148 rdf:type schema:DefinedTerm
149 Nbff19ea1eb084ed6953bbca9a59f9511 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Substrate Specificity
151 rdf:type schema:DefinedTerm
152 Ncfbff8962b844ee189cbaeb24e8c8ac7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Saccharomyces cerevisiae Proteins
154 rdf:type schema:DefinedTerm
155 Nd91d6557dd7d4c1cbf0a3254dc7c39f5 rdf:first sg:person.01044565073.45
156 rdf:rest rdf:nil
157 Ne24e841481644dd59cc2c47ad0fa0f6a rdf:first sg:person.01302364347.32
158 rdf:rest N994b6f09fcb847d4af865d3ef0300721
159 Ne3ec6a4eaf044551812213f822a92856 schema:name Springer Nature - SN SciGraph project
160 rdf:type schema:Organization
161 Nf2176ab2d4d540b684f38dd413ae14d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Acetylation
163 rdf:type schema:DefinedTerm
164 Nf3ab59ae810d49f3a51f3ff4b7dcf057 rdf:first sg:person.01217521510.67
165 rdf:rest N2a46e55d183847c2a815d4e3f076135a
166 Nf3f6d96e186a48deb5d86356ceceb5c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Histones
168 rdf:type schema:DefinedTerm
169 Nf9a1cc066a884f6ba12b8c207d281966 schema:name doi
170 schema:value 10.1038/383269a0
171 rdf:type schema:PropertyValue
172 Nfa0077d425b64389b983b0731fd1f012 schema:volumeNumber 383
173 rdf:type schema:PublicationVolume
174 Nfcccd5672031455dace9f40dad950958 schema:name dimensions_id
175 schema:value pub.1024313273
176 rdf:type schema:PropertyValue
177 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
178 schema:name Biological Sciences
179 rdf:type schema:DefinedTerm
180 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
181 schema:name Genetics
182 rdf:type schema:DefinedTerm
183 sg:journal.1018957 schema:issn 0028-0836
184 1476-4687
185 schema:name Nature
186 schema:publisher Springer Nature
187 rdf:type schema:Periodical
188 sg:person.010356234162.72 schema:affiliation grid-institutes:grid.240145.6
189 schema:familyName Cook
190 schema:givenName Richard G.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010356234162.72
192 rdf:type schema:Person
193 sg:person.01044565073.45 schema:affiliation grid-institutes:grid.16416.34
194 schema:familyName Allis
195 schema:givenName C. David
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044565073.45
197 rdf:type schema:Person
198 sg:person.01160325607.88 schema:affiliation grid-institutes:grid.39382.33
199 schema:familyName Sobel
200 schema:givenName Richard E.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160325607.88
202 rdf:type schema:Person
203 sg:person.01165556153.25 schema:affiliation grid-institutes:grid.16416.34
204 schema:familyName Ranalli
205 schema:givenName Tamara A.
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165556153.25
207 rdf:type schema:Person
208 sg:person.01217521510.67 schema:affiliation grid-institutes:grid.17091.3e
209 schema:familyName Edmondson
210 schema:givenName Diane G.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217521510.67
212 rdf:type schema:Person
213 sg:person.01265634710.97 schema:affiliation grid-institutes:grid.17091.3e
214 schema:familyName Roth
215 schema:givenName Sharon Y.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265634710.97
217 rdf:type schema:Person
218 sg:person.01302364347.32 schema:affiliation grid-institutes:grid.16416.34
219 schema:familyName Brownell
220 schema:givenName James E.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302364347.32
222 rdf:type schema:Person
223 sg:person.0640474631.79 schema:affiliation grid-institutes:grid.16416.34
224 schema:familyName Kuo
225 schema:givenName Min-Hao
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640474631.79
227 rdf:type schema:Person
228 sg:pub.10.1007/bf00290718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049797265
229 https://doi.org/10.1007/bf00290718
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/382319a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052095488
232 https://doi.org/10.1038/382319a0
233 rdf:type schema:CreativeWork
234 grid-institutes:grid.16416.34 schema:alternateName Department of Biology, University of Rochester, 14627, Rochester, New York, USA
235 schema:name Department of Biology, University of Rochester, 14627, Rochester, New York, USA
236 rdf:type schema:Organization
237 grid-institutes:grid.17091.3e schema:alternateName Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada
238 schema:name Zoology Department, University of British Columbia, 6270 University Boulevard, V6T1Z4, Vancouver, BC, Canada
239 rdf:type schema:Organization
240 grid-institutes:grid.240145.6 schema:alternateName Department of Biochemistry and Molecular Biology, M. D. Anderson Cancer Center, 77030, Houston, Texas, USA
241 schema:name Department of Biochemistry and Molecular Biology, M. D. Anderson Cancer Center, 77030, Houston, Texas, USA
242 rdf:type schema:Organization
243 grid-institutes:grid.39382.33 schema:alternateName Department of Microbiology and Immunology, Baylor College of Medicine, 77030, Houston, Texas, USA
244 schema:name Department of Biology, University of Rochester, 14627, Rochester, New York, USA
245 Department of Microbiology and Immunology, Baylor College of Medicine, 77030, Houston, Texas, USA
246 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...