Requirement for Xist in X chromosome inactivation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-01

AUTHORS

G D Penny, G F Kay, S A Sheardown, S Rastan, N Brockdorff

ABSTRACT

The Xist gene has been proposed as a candidate for the X inactivation centre, the master regulatory switch locus that controls X chromosome inactivation. So far this hypothesis has been supported solely by indirect evidence. Here we describe gene targeting of Xist, and provide evidence for its absolute requirement in the process of X chromosome inactivation. More... »

PAGES

131-137

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/379131a0

DOI

http://dx.doi.org/10.1038/379131a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031967155

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8538762


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