Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-04

AUTHORS

Xi He, Jean-Pierre Saint-Jeannet, James R. Woodgett, Harold E. Varmus, Igor B. Dawid

ABSTRACT

Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal. More... »

PAGES

617-622

Journal

TITLE

Nature

ISSUE

6523

VOLUME

374

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/374617a0

DOI

http://dx.doi.org/10.1038/374617a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046370946

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7715701


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blastocyst", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium-Calmodulin-Dependent Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryo, Nonmammalian", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibroblast Growth Factor 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen Synthase Kinase 3", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen Synthase Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultraviolet Rays", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Xenopus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "He", 
        "givenName": "Xi", 
        "id": "sg:person.07570713717.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07570713717.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France", 
          "id": "http://www.grid.ac/institutes/grid.463826.d", 
          "name": [
            "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
            "Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saint-Jeannet", 
        "givenName": "Jean-Pierre", 
        "id": "sg:person.01337326303.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337326303.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada", 
          "id": "http://www.grid.ac/institutes/grid.415224.4", 
          "name": [
            "Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Woodgett", 
        "givenName": "James R.", 
        "id": "sg:person.0731233037.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731233037.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varmus", 
        "givenName": "Harold E.", 
        "id": "sg:person.01341456311.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341456311.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.420089.7", 
          "name": [
            "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dawid", 
        "givenName": "Igor B.", 
        "id": "sg:person.0646120604.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646120604.07"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/367080a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046890704", 
          "https://doi.org/10.1038/367080a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/357252a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023099265", 
          "https://doi.org/10.1038/357252a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367076a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000706869", 
          "https://doi.org/10.1038/367076a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/362557a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005693149", 
          "https://doi.org/10.1038/362557a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/359609a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022638232", 
          "https://doi.org/10.1038/359609a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/363133a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015578449", 
          "https://doi.org/10.1038/363133a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-04", 
    "datePublishedReg": "1995-04-01", 
    "description": "Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/374617a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6523", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "374"
      }
    ], 
    "keywords": [
      "glycogen synthase kinase-3", 
      "synthase kinase-3", 
      "GSK-3", 
      "dorsal differentiation", 
      "kinase 3", 
      "vertebrate pattern formation", 
      "GSK-3 mutants", 
      "early Xenopus development", 
      "GSK-3 activity", 
      "Drosophila development", 
      "dorsoventral patterning", 
      "Xenopus development", 
      "Xenopus embryos", 
      "differentiation", 
      "pattern formation", 
      "ventral differentiation", 
      "wingless", 
      "ventralization", 
      "shaggy", 
      "mutants", 
      "embryos", 
      "patterning", 
      "development", 
      "role", 
      "suppression", 
      "activity", 
      "formation", 
      "signals", 
      "products", 
      "results"
    ], 
    "name": "Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos", 
    "pagination": "617-622", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046370946"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/374617a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "7715701"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/374617a0", 
      "https://app.dimensions.ai/details/publication/pub.1046370946"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_289.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/374617a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/374617a0'


 

This table displays all metadata directly associated to this object as RDF triples.

217 TRIPLES      21 PREDICATES      78 URIs      63 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/374617a0 schema:about N07a55d62984143f8af5892baa98ce1ec
2 N0a6f972b9ffe41bf9e775b5d7ffc5342
3 N0c758d21b2cf41d9bea5886de7d0a22a
4 N3b36294af02644adbde52ff5632506d1
5 N4c7a9966452d4125b6af3ef07d90ef32
6 N8001f41475f1472da038c489a6d4f9af
7 N91b1a4eedae14aecaa3ddf8b3ee13dc5
8 Nc1fbdc59065949dca62dfe781a89d540
9 Nc47dda31c1c24b4b9f210bf9cf850efe
10 Nc6968b1554884259acfda88bb78b6215
11 Nc88f16ba04d1460d8a43378f34fc8565
12 Ncd57a21647114359b264fd8b4a1e7fe5
13 Nd1c1d5bbc66b4d5586a298bb58185426
14 Nd96c8f1ddb924c3e8d35fd3c366a7bf5
15 Nf2ddbbb7f2664ffab12a78f407d0cfbe
16 anzsrc-for:06
17 anzsrc-for:0601
18 anzsrc-for:0604
19 schema:author N0cc39def38c2443bb4302191fd1dd5ca
20 schema:citation sg:pub.10.1038/357252a0
21 sg:pub.10.1038/359609a0
22 sg:pub.10.1038/362557a0
23 sg:pub.10.1038/363133a0
24 sg:pub.10.1038/367076a0
25 sg:pub.10.1038/367080a0
26 schema:datePublished 1995-04
27 schema:datePublishedReg 1995-04-01
28 schema:description Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal.
29 schema:genre article
30 schema:isAccessibleForFree false
31 schema:isPartOf Nd01f26b38d594afa9cbfd618d9968679
32 Nd8a197263e654ffbbcff4ce02b952d46
33 sg:journal.1018957
34 schema:keywords Drosophila development
35 GSK-3
36 GSK-3 activity
37 GSK-3 mutants
38 Xenopus development
39 Xenopus embryos
40 activity
41 development
42 differentiation
43 dorsal differentiation
44 dorsoventral patterning
45 early Xenopus development
46 embryos
47 formation
48 glycogen synthase kinase-3
49 kinase 3
50 mutants
51 pattern formation
52 patterning
53 products
54 results
55 role
56 shaggy
57 signals
58 suppression
59 synthase kinase-3
60 ventral differentiation
61 ventralization
62 vertebrate pattern formation
63 wingless
64 schema:name Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
65 schema:pagination 617-622
66 schema:productId N3af4de465aaa43939d85e2fcd5e4eba3
67 N4fc3fb870beb4126b835ea97229577eb
68 Ncc3f80253bd04dc1bee70199c518edb1
69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046370946
70 https://doi.org/10.1038/374617a0
71 schema:sdDatePublished 2022-09-02T15:47
72 schema:sdLicense https://scigraph.springernature.com/explorer/license/
73 schema:sdPublisher N54a31dacacaa4274872df58546b63a0e
74 schema:url https://doi.org/10.1038/374617a0
75 sgo:license sg:explorer/license/
76 sgo:sdDataset articles
77 rdf:type schema:ScholarlyArticle
78 N07a55d62984143f8af5892baa98ce1ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Molecular Sequence Data
80 rdf:type schema:DefinedTerm
81 N0a6f972b9ffe41bf9e775b5d7ffc5342 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Mutation
83 rdf:type schema:DefinedTerm
84 N0c758d21b2cf41d9bea5886de7d0a22a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Ultraviolet Rays
86 rdf:type schema:DefinedTerm
87 N0cc39def38c2443bb4302191fd1dd5ca rdf:first sg:person.07570713717.64
88 rdf:rest N3cc3969909e541d1975ceef83ed42463
89 N15b3f796f4a044c280d2b7e55b2f2126 rdf:first sg:person.01341456311.48
90 rdf:rest Ndf43ff9e832145eb95bb8cf2c7a45b65
91 N3af4de465aaa43939d85e2fcd5e4eba3 schema:name pubmed_id
92 schema:value 7715701
93 rdf:type schema:PropertyValue
94 N3b36294af02644adbde52ff5632506d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Embryonic Development
96 rdf:type schema:DefinedTerm
97 N3cc3969909e541d1975ceef83ed42463 rdf:first sg:person.01337326303.53
98 rdf:rest Nbe882006ec8c4520afcdd1b61194cbf7
99 N4c7a9966452d4125b6af3ef07d90ef32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Humans
101 rdf:type schema:DefinedTerm
102 N4fc3fb870beb4126b835ea97229577eb schema:name doi
103 schema:value 10.1038/374617a0
104 rdf:type schema:PropertyValue
105 N54a31dacacaa4274872df58546b63a0e schema:name Springer Nature - SN SciGraph project
106 rdf:type schema:Organization
107 N8001f41475f1472da038c489a6d4f9af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name RNA, Messenger
109 rdf:type schema:DefinedTerm
110 N91b1a4eedae14aecaa3ddf8b3ee13dc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Glycogen Synthase Kinases
112 rdf:type schema:DefinedTerm
113 Nbe882006ec8c4520afcdd1b61194cbf7 rdf:first sg:person.0731233037.88
114 rdf:rest N15b3f796f4a044c280d2b7e55b2f2126
115 Nc1fbdc59065949dca62dfe781a89d540 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Embryonic Induction
117 rdf:type schema:DefinedTerm
118 Nc47dda31c1c24b4b9f210bf9cf850efe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Blastocyst
120 rdf:type schema:DefinedTerm
121 Nc6968b1554884259acfda88bb78b6215 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Fibroblast Growth Factor 2
123 rdf:type schema:DefinedTerm
124 Nc88f16ba04d1460d8a43378f34fc8565 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Xenopus
126 rdf:type schema:DefinedTerm
127 Ncc3f80253bd04dc1bee70199c518edb1 schema:name dimensions_id
128 schema:value pub.1046370946
129 rdf:type schema:PropertyValue
130 Ncd57a21647114359b264fd8b4a1e7fe5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Embryo, Nonmammalian
132 rdf:type schema:DefinedTerm
133 Nd01f26b38d594afa9cbfd618d9968679 schema:volumeNumber 374
134 rdf:type schema:PublicationVolume
135 Nd1c1d5bbc66b4d5586a298bb58185426 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Glycogen Synthase Kinase 3
137 rdf:type schema:DefinedTerm
138 Nd8a197263e654ffbbcff4ce02b952d46 schema:issueNumber 6523
139 rdf:type schema:PublicationIssue
140 Nd96c8f1ddb924c3e8d35fd3c366a7bf5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Animals
142 rdf:type schema:DefinedTerm
143 Ndf43ff9e832145eb95bb8cf2c7a45b65 rdf:first sg:person.0646120604.07
144 rdf:rest rdf:nil
145 Nf2ddbbb7f2664ffab12a78f407d0cfbe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Calcium-Calmodulin-Dependent Protein Kinases
147 rdf:type schema:DefinedTerm
148 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
149 schema:name Biological Sciences
150 rdf:type schema:DefinedTerm
151 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
152 schema:name Biochemistry and Cell Biology
153 rdf:type schema:DefinedTerm
154 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
155 schema:name Genetics
156 rdf:type schema:DefinedTerm
157 sg:journal.1018957 schema:issn 0028-0836
158 1476-4687
159 schema:name Nature
160 schema:publisher Springer Nature
161 rdf:type schema:Periodical
162 sg:person.01337326303.53 schema:affiliation grid-institutes:grid.463826.d
163 schema:familyName Saint-Jeannet
164 schema:givenName Jean-Pierre
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337326303.53
166 rdf:type schema:Person
167 sg:person.01341456311.48 schema:affiliation grid-institutes:None
168 schema:familyName Varmus
169 schema:givenName Harold E.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341456311.48
171 rdf:type schema:Person
172 sg:person.0646120604.07 schema:affiliation grid-institutes:grid.420089.7
173 schema:familyName Dawid
174 schema:givenName Igor B.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646120604.07
176 rdf:type schema:Person
177 sg:person.0731233037.88 schema:affiliation grid-institutes:grid.415224.4
178 schema:familyName Woodgett
179 schema:givenName James R.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731233037.88
181 rdf:type schema:Person
182 sg:person.07570713717.64 schema:affiliation grid-institutes:None
183 schema:familyName He
184 schema:givenName Xi
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07570713717.64
186 rdf:type schema:Person
187 sg:pub.10.1038/357252a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023099265
188 https://doi.org/10.1038/357252a0
189 rdf:type schema:CreativeWork
190 sg:pub.10.1038/359609a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022638232
191 https://doi.org/10.1038/359609a0
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/362557a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005693149
194 https://doi.org/10.1038/362557a0
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/363133a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015578449
197 https://doi.org/10.1038/363133a0
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/367076a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000706869
200 https://doi.org/10.1038/367076a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/367080a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046890704
203 https://doi.org/10.1038/367080a0
204 rdf:type schema:CreativeWork
205 grid-institutes:None schema:alternateName Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
206 schema:name Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
207 rdf:type schema:Organization
208 grid-institutes:grid.415224.4 schema:alternateName Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada
209 schema:name Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada
210 rdf:type schema:Organization
211 grid-institutes:grid.420089.7 schema:alternateName Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
212 schema:name Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
213 rdf:type schema:Organization
214 grid-institutes:grid.463826.d schema:alternateName Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France
215 schema:name Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France
216 Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
217 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...