Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-04

AUTHORS

Xi He, Jean-Pierre Saint-Jeannet, James R. Woodgett, Harold E. Varmus, Igor B. Dawid

ABSTRACT

Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal. More... »

PAGES

617-622

Journal

TITLE

Nature

ISSUE

6523

VOLUME

374

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/374617a0

DOI

http://dx.doi.org/10.1038/374617a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046370946

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7715701


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blastocyst", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium-Calmodulin-Dependent Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryo, Nonmammalian", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibroblast Growth Factor 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen Synthase Kinase 3", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen Synthase Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultraviolet Rays", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Xenopus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "He", 
        "givenName": "Xi", 
        "id": "sg:person.07570713717.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07570713717.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France", 
          "id": "http://www.grid.ac/institutes/grid.463826.d", 
          "name": [
            "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
            "Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saint-Jeannet", 
        "givenName": "Jean-Pierre", 
        "id": "sg:person.01337326303.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337326303.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada", 
          "id": "http://www.grid.ac/institutes/grid.415224.4", 
          "name": [
            "Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Woodgett", 
        "givenName": "James R.", 
        "id": "sg:person.0731233037.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731233037.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varmus", 
        "givenName": "Harold E.", 
        "id": "sg:person.01341456311.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341456311.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.420089.7", 
          "name": [
            "Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dawid", 
        "givenName": "Igor B.", 
        "id": "sg:person.0646120604.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646120604.07"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/362557a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005693149", 
          "https://doi.org/10.1038/362557a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367076a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000706869", 
          "https://doi.org/10.1038/367076a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/359609a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022638232", 
          "https://doi.org/10.1038/359609a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367080a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046890704", 
          "https://doi.org/10.1038/367080a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/363133a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015578449", 
          "https://doi.org/10.1038/363133a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/357252a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023099265", 
          "https://doi.org/10.1038/357252a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-04", 
    "datePublishedReg": "1995-04-01", 
    "description": "Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/374617a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6523", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "374"
      }
    ], 
    "keywords": [
      "glycogen synthase kinase-3", 
      "synthase kinase-3", 
      "GSK-3", 
      "dorsal differentiation", 
      "kinase 3", 
      "vertebrate pattern formation", 
      "GSK-3 mutants", 
      "early Xenopus development", 
      "GSK-3 activity", 
      "Drosophila development", 
      "dorsoventral patterning", 
      "Xenopus development", 
      "Xenopus embryos", 
      "differentiation", 
      "pattern formation", 
      "ventral differentiation", 
      "wingless", 
      "ventralization", 
      "shaggy", 
      "mutants", 
      "embryos", 
      "patterning", 
      "development", 
      "role", 
      "suppression", 
      "activity", 
      "formation", 
      "signals", 
      "products", 
      "results"
    ], 
    "name": "Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos", 
    "pagination": "617-622", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046370946"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/374617a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "7715701"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/374617a0", 
      "https://app.dimensions.ai/details/publication/pub.1046370946"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_269.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/374617a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/374617a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/374617a0'


 

This table displays all metadata directly associated to this object as RDF triples.

217 TRIPLES      21 PREDICATES      78 URIs      63 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/374617a0 schema:about N073a43eec5d04c38888f9a8f1e428b96
2 N099a2ac3881e48d09150e3ab06334359
3 N0ffa286af8b9495c88d61f2e42dd4f8a
4 N176cc7d5aa5d4b7b93a2626a2c0d70bf
5 N387a37e9e6c74a05bef3bdd947678ead
6 N3d5b0ba9e5724c5c82fa72932c3017cd
7 N4b0e391dae6547bbb926cb67cffd393f
8 N4faabb3c47294f0fb971c33ce30eea47
9 N5626bc9fa1764f08be21f2e623ba08cf
10 N8aa338419d084024ab6b33a425347b51
11 N8dc86f74258741d5bb2f7be29038f42d
12 N99fa197f781849f0b47f39e981a109fb
13 Na6e8343a254747dc927f952094956e52
14 Nc7d822a30cdf4f7cb5b143fdc0dff3e2
15 Nf14805620c724d9e9f6e4973f2cb045b
16 anzsrc-for:06
17 anzsrc-for:0601
18 anzsrc-for:0604
19 schema:author N2d9154ff88074c6ea3d05cb846b561a1
20 schema:citation sg:pub.10.1038/357252a0
21 sg:pub.10.1038/359609a0
22 sg:pub.10.1038/362557a0
23 sg:pub.10.1038/363133a0
24 sg:pub.10.1038/367076a0
25 sg:pub.10.1038/367080a0
26 schema:datePublished 1995-04
27 schema:datePublishedReg 1995-04-01
28 schema:description Glycogen synthase kinase 3 (GSK-3) is homologous to the product of the Drosophila gene shaggy (zeste-white 3), which is required for signalling by wingless during Drosophila development. To test whether GSK-3 is also involved in vertebrate pattern formation, its role was investigated during early Xenopus development. It was found that dominant-negative GSK-3 mutants induced dorsal differentiation, whereas wild-type GSK-3 induced ventralization. These results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of GSK-3 activity by a wingless/wnt-related signal.
29 schema:genre article
30 schema:isAccessibleForFree false
31 schema:isPartOf Nc3aaefdd427446259a94e6f575754a25
32 Nd14d91c780ef406fb43ffbcf8e085372
33 sg:journal.1018957
34 schema:keywords Drosophila development
35 GSK-3
36 GSK-3 activity
37 GSK-3 mutants
38 Xenopus development
39 Xenopus embryos
40 activity
41 development
42 differentiation
43 dorsal differentiation
44 dorsoventral patterning
45 early Xenopus development
46 embryos
47 formation
48 glycogen synthase kinase-3
49 kinase 3
50 mutants
51 pattern formation
52 patterning
53 products
54 results
55 role
56 shaggy
57 signals
58 suppression
59 synthase kinase-3
60 ventral differentiation
61 ventralization
62 vertebrate pattern formation
63 wingless
64 schema:name Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
65 schema:pagination 617-622
66 schema:productId N3b895d7781eb4c4f856762333039545f
67 N3fa2cef6d85447d88d147cfdaa6a1939
68 Neaf6351135574d539334e3b3dd983963
69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046370946
70 https://doi.org/10.1038/374617a0
71 schema:sdDatePublished 2022-12-01T06:21
72 schema:sdLicense https://scigraph.springernature.com/explorer/license/
73 schema:sdPublisher N2e36fc6ab0674df9979a1dc17959e505
74 schema:url https://doi.org/10.1038/374617a0
75 sgo:license sg:explorer/license/
76 sgo:sdDataset articles
77 rdf:type schema:ScholarlyArticle
78 N073a43eec5d04c38888f9a8f1e428b96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Glycogen Synthase Kinases
80 rdf:type schema:DefinedTerm
81 N099a2ac3881e48d09150e3ab06334359 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Blastocyst
83 rdf:type schema:DefinedTerm
84 N0ffa286af8b9495c88d61f2e42dd4f8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Animals
86 rdf:type schema:DefinedTerm
87 N176cc7d5aa5d4b7b93a2626a2c0d70bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Calcium-Calmodulin-Dependent Protein Kinases
89 rdf:type schema:DefinedTerm
90 N1c51b6da76ae4a90abeebf40e35c012d rdf:first sg:person.0731233037.88
91 rdf:rest N4c45fd7657f941ba82e398283c2c1fd4
92 N2d9154ff88074c6ea3d05cb846b561a1 rdf:first sg:person.07570713717.64
93 rdf:rest N9b5e1db0186d4e13ab6141026dd15074
94 N2e36fc6ab0674df9979a1dc17959e505 schema:name Springer Nature - SN SciGraph project
95 rdf:type schema:Organization
96 N387a37e9e6c74a05bef3bdd947678ead schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Molecular Sequence Data
98 rdf:type schema:DefinedTerm
99 N3b895d7781eb4c4f856762333039545f schema:name dimensions_id
100 schema:value pub.1046370946
101 rdf:type schema:PropertyValue
102 N3d5b0ba9e5724c5c82fa72932c3017cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Xenopus
104 rdf:type schema:DefinedTerm
105 N3fa2cef6d85447d88d147cfdaa6a1939 schema:name pubmed_id
106 schema:value 7715701
107 rdf:type schema:PropertyValue
108 N4b0e391dae6547bbb926cb67cffd393f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name RNA, Messenger
110 rdf:type schema:DefinedTerm
111 N4c45fd7657f941ba82e398283c2c1fd4 rdf:first sg:person.01341456311.48
112 rdf:rest N89c6981213ce4b1ca1ba9ad5b2f7ec2f
113 N4faabb3c47294f0fb971c33ce30eea47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Embryonic Development
115 rdf:type schema:DefinedTerm
116 N5626bc9fa1764f08be21f2e623ba08cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Embryo, Nonmammalian
118 rdf:type schema:DefinedTerm
119 N89c6981213ce4b1ca1ba9ad5b2f7ec2f rdf:first sg:person.0646120604.07
120 rdf:rest rdf:nil
121 N8aa338419d084024ab6b33a425347b51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Glycogen Synthase Kinase 3
123 rdf:type schema:DefinedTerm
124 N8dc86f74258741d5bb2f7be29038f42d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Humans
126 rdf:type schema:DefinedTerm
127 N99fa197f781849f0b47f39e981a109fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Embryonic Induction
129 rdf:type schema:DefinedTerm
130 N9b5e1db0186d4e13ab6141026dd15074 rdf:first sg:person.01337326303.53
131 rdf:rest N1c51b6da76ae4a90abeebf40e35c012d
132 Na6e8343a254747dc927f952094956e52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Ultraviolet Rays
134 rdf:type schema:DefinedTerm
135 Nc3aaefdd427446259a94e6f575754a25 schema:volumeNumber 374
136 rdf:type schema:PublicationVolume
137 Nc7d822a30cdf4f7cb5b143fdc0dff3e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Mutation
139 rdf:type schema:DefinedTerm
140 Nd14d91c780ef406fb43ffbcf8e085372 schema:issueNumber 6523
141 rdf:type schema:PublicationIssue
142 Neaf6351135574d539334e3b3dd983963 schema:name doi
143 schema:value 10.1038/374617a0
144 rdf:type schema:PropertyValue
145 Nf14805620c724d9e9f6e4973f2cb045b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Fibroblast Growth Factor 2
147 rdf:type schema:DefinedTerm
148 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
149 schema:name Biological Sciences
150 rdf:type schema:DefinedTerm
151 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
152 schema:name Biochemistry and Cell Biology
153 rdf:type schema:DefinedTerm
154 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
155 schema:name Genetics
156 rdf:type schema:DefinedTerm
157 sg:journal.1018957 schema:issn 0028-0836
158 1476-4687
159 schema:name Nature
160 schema:publisher Springer Nature
161 rdf:type schema:Periodical
162 sg:person.01337326303.53 schema:affiliation grid-institutes:grid.463826.d
163 schema:familyName Saint-Jeannet
164 schema:givenName Jean-Pierre
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337326303.53
166 rdf:type schema:Person
167 sg:person.01341456311.48 schema:affiliation grid-institutes:None
168 schema:familyName Varmus
169 schema:givenName Harold E.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341456311.48
171 rdf:type schema:Person
172 sg:person.0646120604.07 schema:affiliation grid-institutes:grid.420089.7
173 schema:familyName Dawid
174 schema:givenName Igor B.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646120604.07
176 rdf:type schema:Person
177 sg:person.0731233037.88 schema:affiliation grid-institutes:grid.415224.4
178 schema:familyName Woodgett
179 schema:givenName James R.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731233037.88
181 rdf:type schema:Person
182 sg:person.07570713717.64 schema:affiliation grid-institutes:None
183 schema:familyName He
184 schema:givenName Xi
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07570713717.64
186 rdf:type schema:Person
187 sg:pub.10.1038/357252a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023099265
188 https://doi.org/10.1038/357252a0
189 rdf:type schema:CreativeWork
190 sg:pub.10.1038/359609a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022638232
191 https://doi.org/10.1038/359609a0
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/362557a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005693149
194 https://doi.org/10.1038/362557a0
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/363133a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015578449
197 https://doi.org/10.1038/363133a0
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/367076a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000706869
200 https://doi.org/10.1038/367076a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/367080a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046890704
203 https://doi.org/10.1038/367080a0
204 rdf:type schema:CreativeWork
205 grid-institutes:None schema:alternateName Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
206 schema:name Varmus Laboratory, Bldg 49, Room 4A56, National Cancer Institute, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
207 rdf:type schema:Organization
208 grid-institutes:grid.415224.4 schema:alternateName Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada
209 schema:name Ontario Cancer Institute, M4X 1K9, Toronto, Ontario, Canada
210 rdf:type schema:Organization
211 grid-institutes:grid.420089.7 schema:alternateName Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
212 schema:name Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
213 rdf:type schema:Organization
214 grid-institutes:grid.463826.d schema:alternateName Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France
215 schema:name Centre de Biologie du Developpement, UMR-CNRS 9925, Universite Paul Sabatier, 118 route de Narbonne, 31062, Toulouse cedex, France
216 Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, 20892, Bethesda, Maryland, USA
217 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...