Graft copolymers that exhibit temperature-induced phase transitions over a wide range of pH View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-01

AUTHORS

G Chen, A S Hoffman

ABSTRACT

There are many potential applications of 'intelligent' aqueous polymer systems in medicine, biotechnology, industry and in environmental problems. Many of these polymer systems undergo reversible phase transitions--for example, abrupt changes in volume--in response to external stimuli such as temperature, pH or the nature of the solvent. Most of the polymers studied previously are responsive to only one kind of stimulus. But for some applications, independent responsiveness to several factors, such as temperature and pH, may be required. Here we describe a polymer that undergoes marked solubility changes in water in response to temperature and/or pH changes. The polymer is prepared by grafting temperature-sensitive side chains onto a pH-sensitive backbone. We also find that block copolymers, in which the temperature- and pH-sensitive units alternate along the chain, show similar behaviour. More... »

PAGES

49-52

Journal

TITLE

Nature

ISSUE

6509

VOLUME

373

Author Affiliations

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/373049a0

    DOI

    http://dx.doi.org/10.1038/373049a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1033718293

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7800038


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