Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-12

AUTHORS

Andreas Lüthi, Jean-Paul Laurent, Alexander Figurovt, Dominique Mullert, Melitta Schachnert

ABSTRACT

SYNAPTIC membranes express cell adhesion molecules1. Here we investigate the role of the neural cell adhesion molecules L1 and NCAM in hippocampal long-term potentiation (LTP), a sustained-use-dependent increase in synaptic efficacy that has been impli-cated in learning and memory2. L1 and NCAM mediate cell inter-actions during neural development3 and are strongly expressed in the hippocampus4,5. They cooperate to strengthen L1-dependent cell adhesion6–9 and are coupled to second messenger pathways10–12. We show that LTP in CA1 neurons of rat hippo-campal slices was reduced by application of various L1 and NCAM antibodies, recombinant LI fragments, and upon dissociation of the L1/NCAM complex through oligomannosidic carbohydrates and NCAM peptides. Neither the activation of NMDA (N-methyl-D-aspartate) receptors nor the maintenance of LTP was affected. These results suggest that L1 and NCAM modulate the develop-ment or the stabilization of LTP13. More... »

PAGES

777-779

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/372777a0

DOI

http://dx.doi.org/10.1038/372777a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005371059

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7997264


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Adhesion Molecules, Neuronal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hippocampus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Vitro Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukocyte L1 Antigen Complex", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Long-Term Potentiation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mannose", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, N-Methyl-D-Aspartate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.417570.0", 
          "name": [
            "Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00fcthi", 
        "givenName": "Andreas", 
        "id": "sg:person.015513440604.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015513440604.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.417570.0", 
          "name": [
            "Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Laurent", 
        "givenName": "Jean-Paul", 
        "id": "sg:person.01342406761.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342406761.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.150338.c", 
          "name": [
            "Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Figurovt", 
        "givenName": "Alexander", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.150338.c", 
          "name": [
            "Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mullert", 
        "givenName": "Dominique", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurobiology, Swiss Federal Institute of Technology, CH-8093, H\u00d6nggerbergZurich, Switzerland", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Neurobiology, Swiss Federal Institute of Technology, CH-8093, H\u00d6nggerbergZurich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schachnert", 
        "givenName": "Melitta", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/305427a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046967152", 
          "https://doi.org/10.1038/305427a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/361031a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042608618", 
          "https://doi.org/10.1038/361031a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367455a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009029246", 
          "https://doi.org/10.1038/367455a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1994-12", 
    "datePublishedReg": "1994-12-01", 
    "description": "SYNAPTIC membranes express cell adhesion molecules1. Here we investigate the role of the neural cell adhesion molecules L1 and NCAM in hippocampal long-term potentiation (LTP), a sustained-use-dependent increase in synaptic efficacy that has been impli-cated in learning and memory2. L1 and NCAM mediate cell inter-actions during neural development3 and are strongly expressed in the hippocampus4,5. They cooperate to strengthen L1-dependent cell adhesion6\u20139 and are coupled to second messenger pathways10\u201312. We show that LTP in CA1 neurons of rat hippo-campal slices was reduced by application of various L1 and NCAM antibodies, recombinant LI fragments, and upon dissociation of the L1/NCAM complex through oligomannosidic carbohydrates and NCAM peptides. Neither the activation of NMDA (N-methyl-D-aspartate) receptors nor the maintenance of LTP was affected. These results suggest that L1 and NCAM modulate the develop-ment or the stabilization of LTP13.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/372777a0", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6508", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "372"
      }
    ], 
    "keywords": [
      "long-term potentiation", 
      "hippocampal long-term potentiation", 
      "neural cell adhesion molecule L1", 
      "cell adhesion molecule L1", 
      "adhesion molecule L1", 
      "maintenance of LTP", 
      "molecule L1", 
      "CA1 neurons", 
      "NMDA receptors", 
      "synaptic efficacy", 
      "dependent increase", 
      "synaptic membranes", 
      "NCAM antibodies", 
      "potentiation", 
      "NCAM", 
      "mediate cell", 
      "oligomannosidic carbohydrates", 
      "neurons", 
      "antibodies", 
      "efficacy", 
      "receptors", 
      "NCAM peptides", 
      "activation", 
      "slices", 
      "cells", 
      "impli", 
      "peptides", 
      "L1", 
      "role", 
      "increase", 
      "carbohydrates", 
      "maintenance", 
      "membrane", 
      "results", 
      "fragments", 
      "dissociation", 
      "stabilization", 
      "complexes", 
      "molecules1", 
      "learning", 
      "applications", 
      "cell adhesion molecules1", 
      "adhesion molecules1", 
      "memory2", 
      "NCAM mediate cell", 
      "neural development3", 
      "development3", 
      "L1-dependent cell adhesion6", 
      "cell adhesion6", 
      "adhesion6", 
      "second messenger pathways10", 
      "messenger pathways10", 
      "pathways10", 
      "rat hippo-campal slices", 
      "hippo-campal slices", 
      "recombinant LI fragments", 
      "Li fragments", 
      "L1/NCAM complex", 
      "NCAM complex", 
      "stabilization of LTP13", 
      "LTP13"
    ], 
    "name": "Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM", 
    "pagination": "777-779", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005371059"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/372777a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "7997264"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/372777a0", 
      "https://app.dimensions.ai/details/publication/pub.1005371059"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_255.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/372777a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/372777a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/372777a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/372777a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/372777a0'


 

This table displays all metadata directly associated to this object as RDF triples.

214 TRIPLES      22 PREDICATES      103 URIs      90 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/372777a0 schema:about N416546169cc14769af5584a931996dfe
2 N416f1b7444dd4830b37d62228e505b42
3 N6d396022dbe244e99511ad86fb11745c
4 N8a6726e1c2d649f992ce58fe57507ba1
5 N8adf02b8e4c1421eb12ada4906a01263
6 N97c39053313046e6ab7bba969be23a40
7 N9edc6454a6224f79996e4db42efa4b6a
8 Ncb01c81b0b9e410fbde80f140c1b9c92
9 Nde8059351b6446fa8397a42a8f8fc455
10 Nfb562ff6394f4bf6939d91146ec40680
11 anzsrc-for:06
12 anzsrc-for:0601
13 anzsrc-for:11
14 anzsrc-for:1109
15 schema:author Nd5d3cbb581124f8fbdadbc6f17219482
16 schema:citation sg:pub.10.1038/305427a0
17 sg:pub.10.1038/361031a0
18 sg:pub.10.1038/367455a0
19 schema:datePublished 1994-12
20 schema:datePublishedReg 1994-12-01
21 schema:description SYNAPTIC membranes express cell adhesion molecules1. Here we investigate the role of the neural cell adhesion molecules L1 and NCAM in hippocampal long-term potentiation (LTP), a sustained-use-dependent increase in synaptic efficacy that has been impli-cated in learning and memory2. L1 and NCAM mediate cell inter-actions during neural development3 and are strongly expressed in the hippocampus4,5. They cooperate to strengthen L1-dependent cell adhesion6–9 and are coupled to second messenger pathways10–12. We show that LTP in CA1 neurons of rat hippo-campal slices was reduced by application of various L1 and NCAM antibodies, recombinant LI fragments, and upon dissociation of the L1/NCAM complex through oligomannosidic carbohydrates and NCAM peptides. Neither the activation of NMDA (N-methyl-D-aspartate) receptors nor the maintenance of LTP was affected. These results suggest that L1 and NCAM modulate the develop-ment or the stabilization of LTP13.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree false
25 schema:isPartOf Nd1012a31300447bdaf00247dbb009f23
26 Nfa375f585383478f9ffcdbabed7befe4
27 sg:journal.1018957
28 schema:keywords CA1 neurons
29 L1
30 L1-dependent cell adhesion6
31 L1/NCAM complex
32 LTP13
33 Li fragments
34 NCAM
35 NCAM antibodies
36 NCAM complex
37 NCAM mediate cell
38 NCAM peptides
39 NMDA receptors
40 activation
41 adhesion molecule L1
42 adhesion molecules1
43 adhesion6
44 antibodies
45 applications
46 carbohydrates
47 cell adhesion molecule L1
48 cell adhesion molecules1
49 cell adhesion6
50 cells
51 complexes
52 dependent increase
53 development3
54 dissociation
55 efficacy
56 fragments
57 hippo-campal slices
58 hippocampal long-term potentiation
59 impli
60 increase
61 learning
62 long-term potentiation
63 maintenance
64 maintenance of LTP
65 mediate cell
66 membrane
67 memory2
68 messenger pathways10
69 molecule L1
70 molecules1
71 neural cell adhesion molecule L1
72 neural development3
73 neurons
74 oligomannosidic carbohydrates
75 pathways10
76 peptides
77 potentiation
78 rat hippo-campal slices
79 receptors
80 recombinant LI fragments
81 results
82 role
83 second messenger pathways10
84 slices
85 stabilization
86 stabilization of LTP13
87 synaptic efficacy
88 synaptic membranes
89 schema:name Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM
90 schema:pagination 777-779
91 schema:productId N2eadc1e9690d49709630943ef9c3dd83
92 N4f8f1b12ce1a4ba8b82fd598da8ac1c6
93 N6510aac73337438c9b993f516c1da655
94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005371059
95 https://doi.org/10.1038/372777a0
96 schema:sdDatePublished 2021-11-01T18:00
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N900f91a21fbf45c49ad3c216efb074fd
99 schema:url https://doi.org/10.1038/372777a0
100 sgo:license sg:explorer/license/
101 sgo:sdDataset articles
102 rdf:type schema:ScholarlyArticle
103 N0c9d9b837510418da278c49e449be660 rdf:first N11e9f2fe46644d779de2a5aa6fcbb0c4
104 rdf:rest Nbd4868fdf23f42df82d987f51d866f64
105 N11e9f2fe46644d779de2a5aa6fcbb0c4 schema:affiliation grid-institutes:grid.150338.c
106 schema:familyName Mullert
107 schema:givenName Dominique
108 rdf:type schema:Person
109 N2eadc1e9690d49709630943ef9c3dd83 schema:name dimensions_id
110 schema:value pub.1005371059
111 rdf:type schema:PropertyValue
112 N416546169cc14769af5584a931996dfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Leukocyte L1 Antigen Complex
114 rdf:type schema:DefinedTerm
115 N416f1b7444dd4830b37d62228e505b42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Hippocampus
117 rdf:type schema:DefinedTerm
118 N4f8f1b12ce1a4ba8b82fd598da8ac1c6 schema:name pubmed_id
119 schema:value 7997264
120 rdf:type schema:PropertyValue
121 N51583c119e504be29a69e718040aea28 schema:affiliation grid-institutes:grid.150338.c
122 schema:familyName Figurovt
123 schema:givenName Alexander
124 rdf:type schema:Person
125 N6510aac73337438c9b993f516c1da655 schema:name doi
126 schema:value 10.1038/372777a0
127 rdf:type schema:PropertyValue
128 N6923a26e574f43608dcb348c2f0b1e1c schema:affiliation grid-institutes:None
129 schema:familyName Schachnert
130 schema:givenName Melitta
131 rdf:type schema:Person
132 N6d396022dbe244e99511ad86fb11745c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Rats
134 rdf:type schema:DefinedTerm
135 N8a6726e1c2d649f992ce58fe57507ba1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Receptors, N-Methyl-D-Aspartate
137 rdf:type schema:DefinedTerm
138 N8adf02b8e4c1421eb12ada4906a01263 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Animals
140 rdf:type schema:DefinedTerm
141 N900f91a21fbf45c49ad3c216efb074fd schema:name Springer Nature - SN SciGraph project
142 rdf:type schema:Organization
143 N97c39053313046e6ab7bba969be23a40 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Recombinant Proteins
145 rdf:type schema:DefinedTerm
146 N9edc6454a6224f79996e4db42efa4b6a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name In Vitro Techniques
148 rdf:type schema:DefinedTerm
149 Nab5c5c094e464fe992eadd7db840d3ab rdf:first N51583c119e504be29a69e718040aea28
150 rdf:rest N0c9d9b837510418da278c49e449be660
151 Nbd4868fdf23f42df82d987f51d866f64 rdf:first N6923a26e574f43608dcb348c2f0b1e1c
152 rdf:rest rdf:nil
153 Ncb01c81b0b9e410fbde80f140c1b9c92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Cell Adhesion Molecules, Neuronal
155 rdf:type schema:DefinedTerm
156 Nd1012a31300447bdaf00247dbb009f23 schema:volumeNumber 372
157 rdf:type schema:PublicationVolume
158 Nd5d3cbb581124f8fbdadbc6f17219482 rdf:first sg:person.015513440604.46
159 rdf:rest Ndb50ffd0d7694e4f9df41d636215835c
160 Ndb50ffd0d7694e4f9df41d636215835c rdf:first sg:person.01342406761.07
161 rdf:rest Nab5c5c094e464fe992eadd7db840d3ab
162 Nde8059351b6446fa8397a42a8f8fc455 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Mannose
164 rdf:type schema:DefinedTerm
165 Nfa375f585383478f9ffcdbabed7befe4 schema:issueNumber 6508
166 rdf:type schema:PublicationIssue
167 Nfb562ff6394f4bf6939d91146ec40680 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Long-Term Potentiation
169 rdf:type schema:DefinedTerm
170 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
171 schema:name Biological Sciences
172 rdf:type schema:DefinedTerm
173 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
174 schema:name Biochemistry and Cell Biology
175 rdf:type schema:DefinedTerm
176 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
177 schema:name Medical and Health Sciences
178 rdf:type schema:DefinedTerm
179 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
180 schema:name Neurosciences
181 rdf:type schema:DefinedTerm
182 sg:journal.1018957 schema:issn 0028-0836
183 1476-4687
184 schema:name Nature
185 schema:publisher Springer Nature
186 rdf:type schema:Periodical
187 sg:person.01342406761.07 schema:affiliation grid-institutes:grid.417570.0
188 schema:familyName Laurent
189 schema:givenName Jean-Paul
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342406761.07
191 rdf:type schema:Person
192 sg:person.015513440604.46 schema:affiliation grid-institutes:grid.417570.0
193 schema:familyName Lüthi
194 schema:givenName Andreas
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015513440604.46
196 rdf:type schema:Person
197 sg:pub.10.1038/305427a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046967152
198 https://doi.org/10.1038/305427a0
199 rdf:type schema:CreativeWork
200 sg:pub.10.1038/361031a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042608618
201 https://doi.org/10.1038/361031a0
202 rdf:type schema:CreativeWork
203 sg:pub.10.1038/367455a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009029246
204 https://doi.org/10.1038/367455a0
205 rdf:type schema:CreativeWork
206 grid-institutes:None schema:alternateName Department of Neurobiology, Swiss Federal Institute of Technology, CH-8093, HÖnggerbergZurich, Switzerland
207 schema:name Department of Neurobiology, Swiss Federal Institute of Technology, CH-8093, HÖnggerbergZurich, Switzerland
208 rdf:type schema:Organization
209 grid-institutes:grid.150338.c schema:alternateName Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland
210 schema:name Department of Pharmacology, Centre Medical Universitaire, CH-12114, Geneve, Switzerland
211 rdf:type schema:Organization
212 grid-institutes:grid.417570.0 schema:alternateName Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland
213 schema:name Pharma Division, Preclinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland
214 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...