Protein superfamilles and domain superfolds View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-12

AUTHORS

C A Orengo, D T Jones, J M Thornton

ABSTRACT

As the protein sequence and structure databases expand rapidly a better understanding of the relationships between proteins is required. A classification is considered that extends the sequence-based superfamilies to include proteins with similar function and three-dimensional structures but no sequence similarity. So far there are only nine protein folds known to recur in proteins having neither sequence nor functional similarity. These folds dominate the structure database, representing more than 30 per cent of all determined structures. This observation has implications for protein-fold recognition. More... »

PAGES

631-634

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/372631a0

DOI

http://dx.doi.org/10.1038/372631a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041521574

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7990952


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