Crystal structure of a yeast TBP/TATA-box complex View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1993-10

AUTHORS

Youngchang Kim, James. H. Geiger, Steven Hahn, Paul B. Sigler

ABSTRACT

The 2.5 Å crystal structure of a TATA-box complex with yeast TBP shows that the eight base pairs of the TATA box bind to the concave surface of TBP by bending towards the major groove with unprecedented severity. This produces a wide open, underwound, shallow minor groove which forms a primarily hydrophobic interface with the entire under-surface of the TBP saddle. The severe bend and a positive writhe radically alter the trajectory of the flanking B-form DNA. More... »

PAGES

512-520

Journal

TITLE

Nature

ISSUE

6446

VOLUME

365

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/365512a0

DOI

http://dx.doi.org/10.1038/365512a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045509514

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8413604


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Computer Graphics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crystallography, X-Ray", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytochrome c Group", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytochromes c", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrogen Bonding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nucleic Acid Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Promoter Regions, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Binding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Structure-Activity Relationship", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "TATA Box", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factor TFIIA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factor TFIID", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA", 
          "id": "http://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Youngchang", 
        "id": "sg:person.01002444173.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002444173.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA", 
          "id": "http://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Geiger", 
        "givenName": "James. H.", 
        "id": "sg:person.0617426552.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617426552.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fred Hutchinson Cancer Research Center, 98104, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.270240.3", 
          "name": [
            "Fred Hutchinson Cancer Research Center, 98104, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hahn", 
        "givenName": "Steven", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA", 
          "id": "http://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sigler", 
        "givenName": "Paul B.", 
        "id": "sg:person.01307025762.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307025762.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/295294a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006376603", 
          "https://doi.org/10.1038/295294a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/352497a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050561734", 
          "https://doi.org/10.1038/352497a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/335321a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028596523", 
          "https://doi.org/10.1038/335321a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/359505a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031788927", 
          "https://doi.org/10.1038/359505a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/360040a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051223059", 
          "https://doi.org/10.1038/360040a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1993-10", 
    "datePublishedReg": "1993-10-01", 
    "description": "The 2.5 \u00c5 crystal structure of a TATA-box complex with yeast TBP shows that the eight base pairs of the TATA box bind to the concave surface of TBP by bending towards the major groove with unprecedented severity. This produces a wide open, underwound, shallow minor groove which forms a primarily hydrophobic interface with the entire under-surface of the TBP saddle. The severe bend and a positive writhe radically alter the trajectory of the flanking B-form DNA.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/365512a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6446", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "365"
      }
    ], 
    "keywords": [
      "shallow minor groove", 
      "yeast TBP", 
      "B-form DNA", 
      "base pairs", 
      "major groove", 
      "minor groove", 
      "hydrophobic interface", 
      "crystal structure", 
      "TBP", 
      "complexes", 
      "binds", 
      "DNA", 
      "unprecedented severity", 
      "severe bend", 
      "concave surface", 
      "groove", 
      "structure", 
      "pairs", 
      "writhe", 
      "bend", 
      "surface", 
      "trajectories", 
      "interface", 
      "severity", 
      "saddle"
    ], 
    "name": "Crystal structure of a yeast TBP/TATA-box complex", 
    "pagination": "512-520", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1045509514"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/365512a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8413604"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/365512a0", 
      "https://app.dimensions.ai/details/publication/pub.1045509514"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T20:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_218.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/365512a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/365512a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/365512a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/365512a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/365512a0'


 

This table displays all metadata directly associated to this object as RDF triples.

213 TRIPLES      21 PREDICATES      77 URIs      64 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/365512a0 schema:about N00a7b862b6e04f6d9587ee18f28ef8b2
2 N0299e86906f14761a6cab4f554b6f9ca
3 N046e4931de864dc5bef1090fd67e7f32
4 N21fb54a81580418db0aa9d2c36a2f099
5 N25299dd5493e4883b6611d8f0ea63cce
6 N31aa6b95be984981a6609d86ef17921d
7 N503a11da58034607a9e60248518aefaf
8 N59eb6a295eb046cd9222dd9a08f527ed
9 N6ddebb661dc6405395f6ace39c988f77
10 N6e2bbeb3f3f040378e1fd174e89f0a73
11 N76c61c4c8a34470ab55dd1fd642918fe
12 N7a4fc86cf8774185ade3ff0bfddb03a5
13 N7c68cd8e3a044c39bd7722585995feba
14 N8e1a522493b34dc4ac853f373d7ac741
15 N9da9c309459a4cc5869ac7b9559ab001
16 Na6b93e0a95e74bc79bb3dc4cc24a2029
17 Nb833df1fdbfa4804970a67de828ef430
18 Nb97f59cbcc4147858ab4f90d745948b9
19 Nc8fef7ea1d004a38988ade0810f23faf
20 Nf7e910431c4c44629ea932dc203e2717
21 Nfe6a07837164479d8ed666481a88da3e
22 anzsrc-for:03
23 anzsrc-for:0306
24 schema:author N14ed376bf8b04900b533988251e8e740
25 schema:citation sg:pub.10.1038/295294a0
26 sg:pub.10.1038/335321a0
27 sg:pub.10.1038/352497a0
28 sg:pub.10.1038/359505a0
29 sg:pub.10.1038/360040a0
30 schema:datePublished 1993-10
31 schema:datePublishedReg 1993-10-01
32 schema:description The 2.5 Å crystal structure of a TATA-box complex with yeast TBP shows that the eight base pairs of the TATA box bind to the concave surface of TBP by bending towards the major groove with unprecedented severity. This produces a wide open, underwound, shallow minor groove which forms a primarily hydrophobic interface with the entire under-surface of the TBP saddle. The severe bend and a positive writhe radically alter the trajectory of the flanking B-form DNA.
33 schema:genre article
34 schema:isAccessibleForFree false
35 schema:isPartOf N9a693c766cfd4de382a6483ba155898a
36 Nd137cc53c700448790e06b480f55ab01
37 sg:journal.1018957
38 schema:keywords B-form DNA
39 DNA
40 TBP
41 base pairs
42 bend
43 binds
44 complexes
45 concave surface
46 crystal structure
47 groove
48 hydrophobic interface
49 interface
50 major groove
51 minor groove
52 pairs
53 saddle
54 severe bend
55 severity
56 shallow minor groove
57 structure
58 surface
59 trajectories
60 unprecedented severity
61 writhe
62 yeast TBP
63 schema:name Crystal structure of a yeast TBP/TATA-box complex
64 schema:pagination 512-520
65 schema:productId Na414eab6deab48cfb42b9dac4f5a6955
66 Ndd402e9f7bc94a30a928efe0653e95d6
67 Nea5b64fb14f941a29741a3ea5c014ff5
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045509514
69 https://doi.org/10.1038/365512a0
70 schema:sdDatePublished 2022-11-24T20:47
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher N97f33cd1a8a2431cb3c61c3bcfc4fb9c
73 schema:url https://doi.org/10.1038/365512a0
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N00a7b862b6e04f6d9587ee18f28ef8b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Transcription Factor TFIID
79 rdf:type schema:DefinedTerm
80 N0299e86906f14761a6cab4f554b6f9ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Structure-Activity Relationship
82 rdf:type schema:DefinedTerm
83 N046e4931de864dc5bef1090fd67e7f32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Nucleic Acid Conformation
85 rdf:type schema:DefinedTerm
86 N13cc6f6bcaf848d9b08d10b1c4327c50 rdf:first sg:person.0617426552.55
87 rdf:rest N754ca0fa0cac45bfbcf0a8992153c680
88 N14ed376bf8b04900b533988251e8e740 rdf:first sg:person.01002444173.53
89 rdf:rest N13cc6f6bcaf848d9b08d10b1c4327c50
90 N21fb54a81580418db0aa9d2c36a2f099 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Recombinant Proteins
92 rdf:type schema:DefinedTerm
93 N25299dd5493e4883b6611d8f0ea63cce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Computer Graphics
95 rdf:type schema:DefinedTerm
96 N2da6e2c7bb4e4043bceabd1cdf6851d8 schema:affiliation grid-institutes:grid.270240.3
97 schema:familyName Hahn
98 schema:givenName Steven
99 rdf:type schema:Person
100 N31aa6b95be984981a6609d86ef17921d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Protein Binding
102 rdf:type schema:DefinedTerm
103 N503a11da58034607a9e60248518aefaf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Transcription Factor TFIIA
105 rdf:type schema:DefinedTerm
106 N59eb6a295eb046cd9222dd9a08f527ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Promoter Regions, Genetic
108 rdf:type schema:DefinedTerm
109 N6ddebb661dc6405395f6ace39c988f77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Protein Conformation
111 rdf:type schema:DefinedTerm
112 N6e2bbeb3f3f040378e1fd174e89f0a73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Hydrogen Bonding
114 rdf:type schema:DefinedTerm
115 N754ca0fa0cac45bfbcf0a8992153c680 rdf:first N2da6e2c7bb4e4043bceabd1cdf6851d8
116 rdf:rest N7b107ffd24fb467daa27dec0ff6aad22
117 N76c61c4c8a34470ab55dd1fd642918fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Cytochromes c
119 rdf:type schema:DefinedTerm
120 N7a4fc86cf8774185ade3ff0bfddb03a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name TATA Box
122 rdf:type schema:DefinedTerm
123 N7b107ffd24fb467daa27dec0ff6aad22 rdf:first sg:person.01307025762.45
124 rdf:rest rdf:nil
125 N7c68cd8e3a044c39bd7722585995feba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Cytochrome c Group
127 rdf:type schema:DefinedTerm
128 N8e1a522493b34dc4ac853f373d7ac741 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Amino Acid Sequence
130 rdf:type schema:DefinedTerm
131 N97f33cd1a8a2431cb3c61c3bcfc4fb9c schema:name Springer Nature - SN SciGraph project
132 rdf:type schema:Organization
133 N9a693c766cfd4de382a6483ba155898a schema:volumeNumber 365
134 rdf:type schema:PublicationVolume
135 N9da9c309459a4cc5869ac7b9559ab001 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Transcription Factors
137 rdf:type schema:DefinedTerm
138 Na414eab6deab48cfb42b9dac4f5a6955 schema:name doi
139 schema:value 10.1038/365512a0
140 rdf:type schema:PropertyValue
141 Na6b93e0a95e74bc79bb3dc4cc24a2029 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Crystallography, X-Ray
143 rdf:type schema:DefinedTerm
144 Nb833df1fdbfa4804970a67de828ef430 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Saccharomyces cerevisiae Proteins
146 rdf:type schema:DefinedTerm
147 Nb97f59cbcc4147858ab4f90d745948b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Base Sequence
149 rdf:type schema:DefinedTerm
150 Nc8fef7ea1d004a38988ade0810f23faf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name DNA
152 rdf:type schema:DefinedTerm
153 Nd137cc53c700448790e06b480f55ab01 schema:issueNumber 6446
154 rdf:type schema:PublicationIssue
155 Ndd402e9f7bc94a30a928efe0653e95d6 schema:name pubmed_id
156 schema:value 8413604
157 rdf:type schema:PropertyValue
158 Nea5b64fb14f941a29741a3ea5c014ff5 schema:name dimensions_id
159 schema:value pub.1045509514
160 rdf:type schema:PropertyValue
161 Nf7e910431c4c44629ea932dc203e2717 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Saccharomyces cerevisiae
163 rdf:type schema:DefinedTerm
164 Nfe6a07837164479d8ed666481a88da3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Molecular Sequence Data
166 rdf:type schema:DefinedTerm
167 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
168 schema:name Chemical Sciences
169 rdf:type schema:DefinedTerm
170 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
171 schema:name Physical Chemistry (incl. Structural)
172 rdf:type schema:DefinedTerm
173 sg:journal.1018957 schema:issn 0028-0836
174 1476-4687
175 schema:name Nature
176 schema:publisher Springer Nature
177 rdf:type schema:Periodical
178 sg:person.01002444173.53 schema:affiliation grid-institutes:grid.47100.32
179 schema:familyName Kim
180 schema:givenName Youngchang
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002444173.53
182 rdf:type schema:Person
183 sg:person.01307025762.45 schema:affiliation grid-institutes:grid.47100.32
184 schema:familyName Sigler
185 schema:givenName Paul B.
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307025762.45
187 rdf:type schema:Person
188 sg:person.0617426552.55 schema:affiliation grid-institutes:grid.47100.32
189 schema:familyName Geiger
190 schema:givenName James. H.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617426552.55
192 rdf:type schema:Person
193 sg:pub.10.1038/295294a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006376603
194 https://doi.org/10.1038/295294a0
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/335321a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028596523
197 https://doi.org/10.1038/335321a0
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/352497a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050561734
200 https://doi.org/10.1038/352497a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/359505a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031788927
203 https://doi.org/10.1038/359505a0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/360040a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051223059
206 https://doi.org/10.1038/360040a0
207 rdf:type schema:CreativeWork
208 grid-institutes:grid.270240.3 schema:alternateName Fred Hutchinson Cancer Research Center, 98104, Seattle, Washington, USA
209 schema:name Fred Hutchinson Cancer Research Center, 98104, Seattle, Washington, USA
210 rdf:type schema:Organization
211 grid-institutes:grid.47100.32 schema:alternateName Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA
212 schema:name Department of Molecular Biophysics and Biochemistry and the Howard Hughes Medical Institute, Yale University, 06510, New Haven, Connecticut, USA
213 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...