HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1993-03-25

AUTHORS

Giuseppe Pantaleo, Cecilia Graziosi, James F. Demarest, Luca Butini, Maria Montroni, Cecil H. Fox, Jan M. Orenstein, Donald P. Kotler, Anthony S. Fauci

ABSTRACT

PRIMARY infection with the human immunodeficiency virus (HIV) is generally followed by a burst of viraemia with or without clinical symptoms1–3. This in turn is followed by a prolonged period of clinical latency. During this period there is little, if any, detectable viraemia, the numbers of infected cells in the blood are very low, and it is extremely difficult to demonstrate virus expression in these cells4. We have analysed viral burden and levels of virus replication simultaneously in the blood and lymphoid organs of the same individuals at various stages of HIV disease. Here we report that in early-stage disease there is a dichotomy between the levels of viral burden and virus replication in peripheral blood versus lymphoid organs. HIV disease is active in the lymphoid tissue throughout the period of clinical latency, even at times when minimal viral activity is demonstrated in blood. More... »

PAGES

355-358

Journal

TITLE

Nature

ISSUE

6418

VOLUME

362

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/362355a0

DOI

http://dx.doi.org/10.1038/362355a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041590783

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8455722


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acquired Immunodeficiency Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenoids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dendritic Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Seropositivity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV-1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Situ Hybridization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inclusion Bodies, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymph Nodes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphoid Tissue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microscopy, Electron", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Palatine Tonsil", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.419681.3", 
          "name": [
            "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pantaleo", 
        "givenName": "Giuseppe", 
        "id": "sg:person.0637727703.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637727703.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.419681.3", 
          "name": [
            "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Graziosi", 
        "givenName": "Cecilia", 
        "id": "sg:person.01172126244.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172126244.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.419681.3", 
          "name": [
            "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Demarest", 
        "givenName": "James F.", 
        "id": "sg:person.01354470044.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354470044.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7010.6", 
          "name": [
            "Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Butini", 
        "givenName": "Luca", 
        "id": "sg:person.01246743210.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246743210.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy", 
          "id": "http://www.grid.ac/institutes/grid.7010.6", 
          "name": [
            "Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Montroni", 
        "givenName": "Maria", 
        "id": "sg:person.01216422405.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216422405.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neuropathology, Yale University School of Medicine, 06510, New Haven, Connecticut, USA", 
          "id": "http://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Neuropathology, Yale University School of Medicine, 06510, New Haven, Connecticut, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fox", 
        "givenName": "Cecil H.", 
        "id": "sg:person.0105300523.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105300523.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pathology, George Washington University, 20037, Washington, DC, USA", 
          "id": "http://www.grid.ac/institutes/grid.253615.6", 
          "name": [
            "Department of Pathology, George Washington University, 20037, Washington, DC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Orenstein", 
        "givenName": "Jan M.", 
        "id": "sg:person.01220363220.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220363220.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St Luke's-Roosevelt Hospital Center, 10025, New York, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.240873.a", 
          "name": [
            "St Luke's-Roosevelt Hospital Center, 10025, New York, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kotler", 
        "givenName": "Donald P.", 
        "id": "sg:person.01360762105.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360762105.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA", 
          "id": "http://www.grid.ac/institutes/grid.419681.3", 
          "name": [
            "Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fauci", 
        "givenName": "Anthony S.", 
        "id": "sg:person.01314336573.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314336573.76"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1993-03-25", 
    "datePublishedReg": "1993-03-25", 
    "description": "PRIMARY infection with the human immunodeficiency virus (HIV) is generally followed by a burst of viraemia with or without clinical symptoms1\u20133. This in turn is followed by a prolonged period of clinical latency. During this period there is little, if any, detectable viraemia, the numbers of infected cells in the blood are very low, and it is extremely difficult to demonstrate virus expression in these cells4. We have analysed viral burden and levels of virus replication simultaneously in the blood and lymphoid organs of the same individuals at various stages of HIV disease. Here we report that in early-stage disease there is a dichotomy between the levels of viral burden and virus replication in peripheral blood versus lymphoid organs. HIV disease is active in the lymphoid tissue throughout the period of clinical latency, even at times when minimal viral activity is demonstrated in blood.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/362355a0", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6418", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "362"
      }
    ], 
    "keywords": [
      "human immunodeficiency virus", 
      "viral burden", 
      "HIV disease", 
      "lymphoid organs", 
      "lymphoid tissue", 
      "clinical latency", 
      "virus replication", 
      "early-stage disease", 
      "HIV infection", 
      "immunodeficiency virus", 
      "peripheral blood", 
      "primary infection", 
      "detectable viraemia", 
      "virus expression", 
      "latent stage", 
      "disease", 
      "viral activity", 
      "blood", 
      "infected cells", 
      "viraemia", 
      "infection", 
      "burden", 
      "same individual", 
      "organs", 
      "tissue", 
      "period", 
      "latency", 
      "virus", 
      "levels", 
      "replication", 
      "cells4", 
      "cells", 
      "expression", 
      "individuals", 
      "stage", 
      "activity", 
      "bursts", 
      "number", 
      "time", 
      "turn", 
      "dichotomy"
    ], 
    "name": "HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease", 
    "pagination": "355-358", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1041590783"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/362355a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8455722"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/362355a0", 
      "https://app.dimensions.ai/details/publication/pub.1041590783"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_253.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/362355a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/362355a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/362355a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/362355a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/362355a0'


 

This table displays all metadata directly associated to this object as RDF triples.

258 TRIPLES      20 PREDICATES      88 URIs      79 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/362355a0 schema:about N0674eaec0d5e4659996459a23fab5dff
2 N21d770efff6142768216fb66ea785e2f
3 N52264e97635241a48e242815800cfe39
4 N5338665f8a9f42ae991598eadf18d93e
5 N5516966143304346850d23f7d60fd651
6 N6287bf02e3a44278a4731a6a228f971d
7 N6ff7ff029fc549bfbba46104b7b44234
8 N8b96fc89b3cc4725a9835b20cb42b90a
9 Na932ba5fc6e3430babe5002e557ea53d
10 Nb2c196c047dd4ae7b27699983450163b
11 Nb4efe0d250544e6f9e3a13149958b670
12 Nb60e4b01985e49fc81400adfe603034e
13 Nbbf76b1caa6448a7b0c74d0d536fc375
14 Ndcf62515268649178e4c4564725d4917
15 Nde320a6ea64a43469fba2d90160022d9
16 Ndfba4dfc94e4446e8885ede2de9fc6e9
17 Ne899b42600974990aa9aa5945344dd58
18 Nf291c7ff1eb148448007dcf6bd59bbe6
19 Nf4eaec8a249f424aad0ac11b6bb93c93
20 Nf54fb404a38642528f7712dacf5865ef
21 Nf8a89cb23f2e4169a603c9cbd4ca6665
22 anzsrc-for:11
23 anzsrc-for:1103
24 anzsrc-for:1108
25 schema:author N25d1de7ab0a54a248dc6929ec94debe0
26 schema:datePublished 1993-03-25
27 schema:datePublishedReg 1993-03-25
28 schema:description PRIMARY infection with the human immunodeficiency virus (HIV) is generally followed by a burst of viraemia with or without clinical symptoms1–3. This in turn is followed by a prolonged period of clinical latency. During this period there is little, if any, detectable viraemia, the numbers of infected cells in the blood are very low, and it is extremely difficult to demonstrate virus expression in these cells4. We have analysed viral burden and levels of virus replication simultaneously in the blood and lymphoid organs of the same individuals at various stages of HIV disease. Here we report that in early-stage disease there is a dichotomy between the levels of viral burden and virus replication in peripheral blood versus lymphoid organs. HIV disease is active in the lymphoid tissue throughout the period of clinical latency, even at times when minimal viral activity is demonstrated in blood.
29 schema:genre article
30 schema:isAccessibleForFree false
31 schema:isPartOf N1da5d98c2598459890ba2039ea2eeafa
32 N759dd59b737b49598d658e21076a052d
33 sg:journal.1018957
34 schema:keywords HIV disease
35 HIV infection
36 activity
37 blood
38 burden
39 bursts
40 cells
41 cells4
42 clinical latency
43 detectable viraemia
44 dichotomy
45 disease
46 early-stage disease
47 expression
48 human immunodeficiency virus
49 immunodeficiency virus
50 individuals
51 infected cells
52 infection
53 latency
54 latent stage
55 levels
56 lymphoid organs
57 lymphoid tissue
58 number
59 organs
60 period
61 peripheral blood
62 primary infection
63 replication
64 same individual
65 stage
66 time
67 tissue
68 turn
69 viraemia
70 viral activity
71 viral burden
72 virus
73 virus expression
74 virus replication
75 schema:name HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
76 schema:pagination 355-358
77 schema:productId N3d7cbfb4fffd4711a7dd73a73878740b
78 N5c561ee454254078b184295b70604d5b
79 Nc7c06aacb65b41979aef683913ab0f1e
80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041590783
81 https://doi.org/10.1038/362355a0
82 schema:sdDatePublished 2022-10-01T06:29
83 schema:sdLicense https://scigraph.springernature.com/explorer/license/
84 schema:sdPublisher N75d38a4bdf9f4f5d92bf223a6eacfff0
85 schema:url https://doi.org/10.1038/362355a0
86 sgo:license sg:explorer/license/
87 sgo:sdDataset articles
88 rdf:type schema:ScholarlyArticle
89 N0674eaec0d5e4659996459a23fab5dff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Lymph Nodes
91 rdf:type schema:DefinedTerm
92 N0d726e7f88b048f687e56b0775198d5a rdf:first sg:person.01246743210.19
93 rdf:rest Nf6c020a7dd144e14aec734b5a2a411f9
94 N0feceaa5b4304e58875442cab27de371 rdf:first sg:person.0105300523.17
95 rdf:rest N4a145b941a8f4b1eac321226ad64ab55
96 N1abbaa72c6b448ebafb746ed35ffd9cb rdf:first sg:person.01172126244.96
97 rdf:rest Ncbc56bd5ae6e4d22926b56d7db497baf
98 N1da5d98c2598459890ba2039ea2eeafa schema:issueNumber 6418
99 rdf:type schema:PublicationIssue
100 N21d770efff6142768216fb66ea785e2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name HIV Infections
102 rdf:type schema:DefinedTerm
103 N25d1de7ab0a54a248dc6929ec94debe0 rdf:first sg:person.0637727703.69
104 rdf:rest N1abbaa72c6b448ebafb746ed35ffd9cb
105 N3d7cbfb4fffd4711a7dd73a73878740b schema:name dimensions_id
106 schema:value pub.1041590783
107 rdf:type schema:PropertyValue
108 N4a145b941a8f4b1eac321226ad64ab55 rdf:first sg:person.01220363220.67
109 rdf:rest N7cf78c590c4d426787f7a26a820defde
110 N52264e97635241a48e242815800cfe39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Blood
112 rdf:type schema:DefinedTerm
113 N5338665f8a9f42ae991598eadf18d93e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Child, Preschool
115 rdf:type schema:DefinedTerm
116 N5516966143304346850d23f7d60fd651 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Lymphoid Tissue
118 rdf:type schema:DefinedTerm
119 N5c561ee454254078b184295b70604d5b schema:name doi
120 schema:value 10.1038/362355a0
121 rdf:type schema:PropertyValue
122 N6287bf02e3a44278a4731a6a228f971d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Palatine Tonsil
124 rdf:type schema:DefinedTerm
125 N6ff7ff029fc549bfbba46104b7b44234 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Dendritic Cells
127 rdf:type schema:DefinedTerm
128 N759dd59b737b49598d658e21076a052d schema:volumeNumber 362
129 rdf:type schema:PublicationVolume
130 N75d38a4bdf9f4f5d92bf223a6eacfff0 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 N7cf78c590c4d426787f7a26a820defde rdf:first sg:person.01360762105.15
133 rdf:rest N81d65cf60e5048e5b4ec724044257f54
134 N81d65cf60e5048e5b4ec724044257f54 rdf:first sg:person.01314336573.76
135 rdf:rest rdf:nil
136 N8b96fc89b3cc4725a9835b20cb42b90a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Microscopy, Electron
138 rdf:type schema:DefinedTerm
139 Na932ba5fc6e3430babe5002e557ea53d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Inclusion Bodies, Viral
141 rdf:type schema:DefinedTerm
142 Nb2c196c047dd4ae7b27699983450163b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Adult
144 rdf:type schema:DefinedTerm
145 Nb4efe0d250544e6f9e3a13149958b670 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Lymphocytes
147 rdf:type schema:DefinedTerm
148 Nb60e4b01985e49fc81400adfe603034e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Acquired Immunodeficiency Syndrome
150 rdf:type schema:DefinedTerm
151 Nbbf76b1caa6448a7b0c74d0d536fc375 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name HIV-1
153 rdf:type schema:DefinedTerm
154 Nc7c06aacb65b41979aef683913ab0f1e schema:name pubmed_id
155 schema:value 8455722
156 rdf:type schema:PropertyValue
157 Ncbc56bd5ae6e4d22926b56d7db497baf rdf:first sg:person.01354470044.43
158 rdf:rest N0d726e7f88b048f687e56b0775198d5a
159 Ndcf62515268649178e4c4564725d4917 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Humans
161 rdf:type schema:DefinedTerm
162 Nde320a6ea64a43469fba2d90160022d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Polymerase Chain Reaction
164 rdf:type schema:DefinedTerm
165 Ndfba4dfc94e4446e8885ede2de9fc6e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name DNA, Viral
167 rdf:type schema:DefinedTerm
168 Ne899b42600974990aa9aa5945344dd58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Male
170 rdf:type schema:DefinedTerm
171 Nf291c7ff1eb148448007dcf6bd59bbe6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Female
173 rdf:type schema:DefinedTerm
174 Nf4eaec8a249f424aad0ac11b6bb93c93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name HIV Seropositivity
176 rdf:type schema:DefinedTerm
177 Nf54fb404a38642528f7712dacf5865ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Adenoids
179 rdf:type schema:DefinedTerm
180 Nf6c020a7dd144e14aec734b5a2a411f9 rdf:first sg:person.01216422405.00
181 rdf:rest N0feceaa5b4304e58875442cab27de371
182 Nf8a89cb23f2e4169a603c9cbd4ca6665 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name In Situ Hybridization
184 rdf:type schema:DefinedTerm
185 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
186 schema:name Medical and Health Sciences
187 rdf:type schema:DefinedTerm
188 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
189 schema:name Clinical Sciences
190 rdf:type schema:DefinedTerm
191 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
192 schema:name Medical Microbiology
193 rdf:type schema:DefinedTerm
194 sg:journal.1018957 schema:issn 0028-0836
195 1476-4687
196 schema:name Nature
197 schema:publisher Springer Nature
198 rdf:type schema:Periodical
199 sg:person.0105300523.17 schema:affiliation grid-institutes:grid.47100.32
200 schema:familyName Fox
201 schema:givenName Cecil H.
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105300523.17
203 rdf:type schema:Person
204 sg:person.01172126244.96 schema:affiliation grid-institutes:grid.419681.3
205 schema:familyName Graziosi
206 schema:givenName Cecilia
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172126244.96
208 rdf:type schema:Person
209 sg:person.01216422405.00 schema:affiliation grid-institutes:grid.7010.6
210 schema:familyName Montroni
211 schema:givenName Maria
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216422405.00
213 rdf:type schema:Person
214 sg:person.01220363220.67 schema:affiliation grid-institutes:grid.253615.6
215 schema:familyName Orenstein
216 schema:givenName Jan M.
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220363220.67
218 rdf:type schema:Person
219 sg:person.01246743210.19 schema:affiliation grid-institutes:grid.7010.6
220 schema:familyName Butini
221 schema:givenName Luca
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246743210.19
223 rdf:type schema:Person
224 sg:person.01314336573.76 schema:affiliation grid-institutes:grid.419681.3
225 schema:familyName Fauci
226 schema:givenName Anthony S.
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314336573.76
228 rdf:type schema:Person
229 sg:person.01354470044.43 schema:affiliation grid-institutes:grid.419681.3
230 schema:familyName Demarest
231 schema:givenName James F.
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354470044.43
233 rdf:type schema:Person
234 sg:person.01360762105.15 schema:affiliation grid-institutes:grid.240873.a
235 schema:familyName Kotler
236 schema:givenName Donald P.
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360762105.15
238 rdf:type schema:Person
239 sg:person.0637727703.69 schema:affiliation grid-institutes:grid.419681.3
240 schema:familyName Pantaleo
241 schema:givenName Giuseppe
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637727703.69
243 rdf:type schema:Person
244 grid-institutes:grid.240873.a schema:alternateName St Luke's-Roosevelt Hospital Center, 10025, New York, New York, USA
245 schema:name St Luke's-Roosevelt Hospital Center, 10025, New York, New York, USA
246 rdf:type schema:Organization
247 grid-institutes:grid.253615.6 schema:alternateName Department of Pathology, George Washington University, 20037, Washington, DC, USA
248 schema:name Department of Pathology, George Washington University, 20037, Washington, DC, USA
249 rdf:type schema:Organization
250 grid-institutes:grid.419681.3 schema:alternateName Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA
251 schema:name Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland, USA
252 rdf:type schema:Organization
253 grid-institutes:grid.47100.32 schema:alternateName Department of Neuropathology, Yale University School of Medicine, 06510, New Haven, Connecticut, USA
254 schema:name Department of Neuropathology, Yale University School of Medicine, 06510, New Haven, Connecticut, USA
255 rdf:type schema:Organization
256 grid-institutes:grid.7010.6 schema:alternateName Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy
257 schema:name Department of Internal Medicine, University of Ancona, 60020, Ancona, Italy
258 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...